The promoter of Rv0560c is induced by salicylate and structurally-related compounds in Mycobacterium tuberculosis

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Schuessler, Dorothée L ^a,b   Parish, Tanya ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; AMINOSALICYLIC ACID; BACTERIAL PROTEIN; BENZOIC ACID; FENOFIBRATE; GEMFIBROZIL; MENADIONE; METHYLTRANSFERASE; RV 0560C; RV 0561C; SALICYLIC ACID; UNCLASSIFIED DRUG; BETA GALACTOSIDASE; IRON; SALICYLIC ACID DERIVATIVE;

ARTICLE; BINDING SITE; CONSENSUS SEQUENCE; DOSE RESPONSE; ENERGY METABOLISM; GENE EXPRESSION; GENE MUTATION; IRON DEPLETION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHENOTYPE; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; AMINO ACID SEQUENCE; APRAXIA; BIOSYNTHESIS; DNA SEQUENCE; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; MULTIDRUG RESISTANCE; MUTATION; NUCLEOTIDE SEQUENCE; REPORTER GENE;

CORYNEBACTERINEAE; MYCOBACTERIUM TUBERCULOSIS;

AMINO ACID SEQUENCE; APRAXIA, IDEOMOTOR; BACTERIAL PROTEINS; BASE SEQUENCE; BETA-GALACTOSIDASE; CONSENSUS SEQUENCE; DRUG RESISTANCE, MULTIPLE, BACTERIAL; GENE EXPRESSION REGULATION, BACTERIAL; GENES, REPORTER; IRON; MOLECULAR SEQUENCE DATA; MUTATION; MYCOBACTERIUM TUBERCULOSIS; PROMOTER REGIONS, GENETIC; SALICYLATES; SEQUENCE ANALYSIS, DNA;

EID: 84859220964     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034471     Document Type: Article

References (59)

1. WHO (2009) Global tuberculosis control: Epidemiology, strategy, financing. World Health Organization report.
2. Russell DG, Barry CE, Flynn JL, (2010) Tuberculosis: what we don't know can, and does, hurt us. Science 328: 852-856.
3. Ulrichs T, Kaufmann SH, (2006) New insights into the function of granulomas in human tuberculosis. J Pathol 208: 261-269.
4. Young M, Mukamolova GV, Kaprelyants AS, (2005) Mycobacterial dormancy and its relation to persistence. In: Parish T, editors. Mycobacterium: Molecular Microbiology: Horizon bioscience pp. 265-320.
5. Stewart GR, Papatheodorou I, Young D, (2005) The stress response. In: Parish T, editors. Mycobacterium: Molecular Microbiology: Horizon Bioscience pp. 245-265.
6. Weinberg ED, (1999) The role of iron in protozoan and fungal infectious diseases. J Eukaryot Microbiol 46: 231-238.
7. Weinberg ED, (2009) Iron availability and infection. Biochim Biophys Acta 1790: 600-605.
8. Barclay R, Ratledge C, (1988) Mycobactins and exochelins of Mycobacterium tuberculosis, M. bovis, M. africanum and other related species. J Gen Microbiol 134: 771-776.
9. Ratledge C, Ewing M, (1996) The occurrence of carboxymycobactin, the siderophore of pathogenic mycobacteria, as a second extracellular siderophore in Mycobacterium smegmatis. Microbiology 142: 2207-2212.
10. De Voss JJ, Rutter K, Schroeder BG, Su H, Zhu Y, et al. (2000) The salicylate-derived mycobactin siderophores of Mycobacterium tuberculosis are essential for growth in macrophages. Proc Natl Acad Sci U S A 97: 1252-1257.
11. Rodriguez GM, Voskuil MI, Gold B, Schoolnik GK, Smith I, (2002) ideR, An essential gene in Mycobacterium tuberculosis: role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress response. Infect Immun 70: 3371-3381.
12. Schnappinger D, Ehrt S, Voskuil MI, Liu Y, Mangan JA, et al. (2003) Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: insights into the phagosomal environment. J Exp Med 198: 693-704.
13. Bacon J, Dover LG, Hatch KA, Zhang Y, Gomes JM, et al. (2007) Lipid composition and transcriptional response of Mycobacterium tuberculosis grown under iron-limitation in continuous culture: identification of a novel wax ester. Microbiology 153: 1435-1444.
14. Quadri LE, Sello J, Keating TA, Weinreb PH, Walsh CT, (1998) Identification of a Mycobacterium tuberculosis gene cluster encoding the biosynthetic enzymes for assembly of the virulence-conferring siderophore mycobactin. Chem Biol 5: 631-645.
15. Harrison AJ, Yu M, Gardenborg T, Middleditch M, Ramsay RJ, et al. (2006) The structure of MbtI from Mycobacterium tuberculosis, the first enzyme in the biosynthesis of the siderophore mycobactin, reveals it to be a salicylate synthase. J Bacteriol 188: 6081-6091.
16. Zwahlen J, Kolappan S, Zhou R, Kisker C, Tonge PJ, (2007) Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis. Biochemistry 46: 954-964.
17. Ratledge C, Marshall BJ, (1972) Iron transport in Mycobacterium smegmatis: the role of mycobactin. Biochim Biophys Acta 279: 58-74.
18. Ratledge C, Winder FG, (1962) The accumulation of salicylic acid by mycobacteria during growth on an iron-deficient medium. Biochem J 84: 501-506.
19. Ratledge C, (2004) Iron, mycobacteria and tuberculosis. Tuberculosis (Edinb) 84: 110-130.
20. Schaller A, Sun Z, Yang Y, Somoskovi A, Zhang Y, (2002) Salicylate reduces susceptibility of Mycobacterium tuberculosis to multiple antituberculosis drugs. Antimicrob Ag Chemother 46: 2636-2639.
21. Price CT, Lee IR, Gustafson JE, (2000) The effects of salicylate on bacteria. Int J Biochem Cell Biol 32: 1029-1043.
22. Rosner JL, (1985) Nonheritable resistance to chloramphenicol and other antibiotics induced by salicylates and other chemotactic repellents in Escherichia coli K-12. Proc Natl Acad Sci U S A 82: 8771-8774.
23. Gustafson JE, Candelaria PV, Fisher SA, Goodridge JP, Lichocik TM, et al. (1999) Growth in the presence of salicylate increases fluoroquinolone resistance in Staphylococcus aureus. Antimicrob Agents Chemother 43: 990-992.
24. Shen Z, Pu XY, Zhang Q, (2011) Salicylate functions as an efflux pump inducer and promotes the emergence of fluoroquinolone-resistant mutants in Campylobacter jejuni. Appl Environ Microbiol 77: 7128-7133.
25. Denkin S, Byrne S, Jie C, Zhang Y, (2005) Gene expression profiling analysis of Mycobacterium tuberculosis genes in response to salicylate. Arch Microbiol 184: 152-157.
26. Sun Z, Cheng SJ, Zhang H, Zhang Y, (2001) Salicylate uniquely induces a 27-kDa protein in tubercle bacillus. FEMS Microbiol Lett 203: 211-216.
27. Garbe TR, (2004) Co-induction of methyltransferase Rv0560c by naphthoquinones and fibric acids suggests attenuation of isoprenoid quinone action in Mycobacterium tuberculosis. Can J Microbiol 50: 771-778.
28. Starck J, Kallenius G, Marklund BI, Andersson DI, Akerlund T, (2004) Comparative proteome analysis of Mycobacterium tuberculosis grown under aerobic and anaerobic conditions. Microbiology 150: 3821-3829.
29. Carroll P, James J, (2008) Assaying promoter activity using LacZ and GFP as reporters. Methods in Molecular Biology pp. 265-277.
30. Blokpoel MC, O'Toole R, Smeulders MJ, Williams HD, (2003) Development and application of unstable GFP variants to kinetic studies of mycobacterial gene expression. J Microbiol Methods 54: 203-211.
31. Manganelli R, Provvedi R, Rodrigue S, Beaucher J, Gaudreau L, et al. (2004) Sigma factors and global gene regulation in Mycobacterium tuberculosis. J Bacteriol 186: 895-902.
32. Bashyam MD, Tyagi AK, (1998) Identification and analysis of "extended -10" promoters from mycobacteria. J Bacteriol 180: 2568-2573.
33. Papavinasasundaram KG, Anderson C, Brooks PC, Thomas NA, Movahedzadeh F, et al. (2001) Slow induction of RecA by DNA damage in Mycobacterium tuberculosis. Microbiology 147: 3271-3279.
34. Agarwal N, Tyagi AK, (2003) Role of 5′-TGN-3′ motif in the interaction of mycobacterial RNA polymerase with a promoter of 'extended -10' class. FEMS Microbiol Lett 225: 75-83.
35. Amin AG, Goude R, Shi L, Zhang J, Chatterjee D, et al. (2008) EmbA is an essential arabinosyltransferase in Mycobacterium tuberculosis. Microbiology 154: 240-248.
36. Carroll P, Schreuder LJ, Muwanguzi-Karugaba J, Wiles S, Robertson BD, et al. (2010) Sensitive detection of gene expression in mycobacteria under replicating and non-replicating conditions using optimized far-red reporters. PLoS ONE 5: e9823.
37. Fivian-Hughes AS, Davis EO, (2010) Analyzing the regulatory role of the HigA antitoxin within Mycobacterium tuberculosis. J Bacteriol 192: 4348-4356.
38. Rickman L, Scott C, Hunt DM, Hutchinson T, Menendez MC, et al. (2005) A member of the cAMP receptor protein family of transcription regulators in Mycobacterium tuberculosis is required for virulence in mice and controls transcription of the rpfA gene coding for a resuscitation promoting factor. Mol Microbiol 56: 1274-1286.
39. Triccas JA, Britton WJ, Gicquel B, (2001) Isolation of strong expression signals of Mycobacterium tuberculosis. Microbiology 147: 1253-1258.
40. Agarwal N, Raghunand TR, Bishai WR, (2006) Regulation of the expression of whiB1 in Mycobacterium tuberculosis: role of cAMP receptor protein. Microbiology 152: 2749-2756.
41. Chauhan S, Sharma D, Singh A, Surolia A, Tyagi JS, (2011) Comprehensive insights into Mycobacterium tuberculosis DevR (DosR) regulon activation switch. Nucl Ac Res 39: 7400-7414.
42. Ehrt S, Guo XV, Hickey CM, Ryou M, Monteleone M, et al. (2005) Controlling gene expression in mycobacteria with anhydrotetracycline and Tet repressor. Nucl Ac Res 33: e21.
43. Blokpoel MC, Murphy HN, O'Toole R, Wiles S, Runn ES, et al. (2005) Tetracycline-inducible gene regulation in mycobacteria. Nucl Ac Res 33: e22.
44. Forti F, Crosta A, Ghisotti D, (2009) Pristinamycin-inducible gene regulation in mycobacteria. J Biotechnol 140: 270-277.
45. Carroll P, Faray-Kele MC, Parish T, (2011) Identifying vulnerable pathways in Mycobacterium tuberculosis by using a knock-down approach. Appl Environ Microbiol 77: 5040-5043.
46. Carroll P, Muttucumaru DGN, Parish T, (2005) Use of a tetracycline-inducible system for conditional expression in Mycobacterium tuberculosis and Mycobacterium smegmatis. Appl Environ Microbiol 71: 3077-3084.
47. Cole ST, Brosch R, Parkhill J, Garnier T, Churcher C, et al. (1998) Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393: 537-544.
48. Collins MD, Jones D, (1981) Distribution of isoprenoid quinone structural types in bacteria and their taxonomic implication. Microbiol Rev 45: 316-354.
49. Collins MD, Pirouz T, Goodfellow M, Minnikin DE, (1977) Distribution of menaquinones in actinomycetes and corynebacteria. J Gen Microbiol 100: 221-230.
50. Weinstein EA, Yano T, Li LS, Avarbock D, Avarbock A, et al. (2005) Inhibitors of type II NADH:menaquinone oxidoreductase represent a class of antitubercular drugs. Proc Natl Acad Sci U S A 102: 4548-4553.
51. Kurosu M, Crick DC, (2009) MenA is a promising drug target for developing novel lead molecules to combat Mycobacterium tuberculosis. Med Chem 5: 197-207.
52. Honaker RW, Dhiman RK, Narayanasamy P, Crick DC, Voskuil MI, (2010) DosS responds to a reduced electron transport system to induce the Mycobacterium tuberculosis DosR regulon. J Bacteriol 192: 6447-6455.
53. Balazsi G, Heath AP, Shi L, Gennaro ML, (2008) The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol Syst Biol 4: 225.
54. Holsclaw CM, Sogi KM, Gilmore SA, Schelle MW, Leavell MD, et al. (2008) Structural characterization of a novel sulfated menaquinone produced by stf3 from Mycobacterium tuberculosis. ACS Chem Biol 3: 619-624.
55. Pomposiello PJ, Bennik MH, Demple B, (2001) Genome-wide transcriptional profiling of the Escherichia coli responses to superoxide stress and sodium salicylate. J Bacteriol 183: 3890-3902.
56. Alekshun MN, Levy SB, (1997) Regulation of chromosomally mediated multiple antibiotic resistance: the mar regulon. Antimicrob Ag Chemother 41: 2067-2075.
57. Dussurget O, Timm J, Gomez M, Gold B, Yu S, et al. (1999) Transcriptional control of the iron-responsive fxbA gene by the mycobacterial regulator IdeR. J Bacteriol 181: 3402-3408.
58. Parish T, Stoker NG, (1998) Electroporation of mycobacteria. Methods Mol Biol 101: 129-144.
59. Miller JH, eds. (1972) Experiments in Molecular Genetics Cold Spring Harbor Cold Spring Harbor Press.