A novel indole derivative compound GY3 improves glucose and lipid metabolism via activation of AMP-activated protein kinase pathway

European Journal of Pharmacology

Volumn 698, Issue 1-3, 2013, Pages 480-488

  Si, Meimei ^a   Yan, Youyou ^a   Tang, Lei ^b   Wu, Honghai ^a   Yang, Bo ^a   He, Qiaojun ^a   Wu, Haoshu ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b GUIZHOU MEDICAL UNIVERSITY   (China)

Author keywords

AMPK; Diabetes; Fatty liver; Glucose metabolism; Indole derivative compound; Lipid metabolism

Indexed keywords

FATTY ACID; GY 3; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INDOLE DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE; ROSIGLITAZONE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL STRAIN 3T3; CELL STRAIN HEPG2; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; GLUCOSE INTAKE; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPID METABOLISM; LIPID STORAGE; LIVER; MALE; NONHUMAN; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL;

3T3-L1 CELLS; ADIPOCYTES; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CELL DIFFERENTIATION; ENZYME ACTIVATION; FATTY ACIDS, NONESTERIFIED; GLUCOSE; HEP G2 CELLS; HUMANS; INDOLEACETIC ACIDS; INTRACELLULAR SPACE; LIPID METABOLISM; LIVER; MALE; MICE; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TRIGLYCERIDES;

EID: 84871923849     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.10.006     Document Type: Article

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