Potent inhibition of human neutrophil activations by bractelactone, A novel chalcone from Fissistigma bracteolatum

Toxicology and Applied Pharmacology

Volumn 266, Issue 3, 2013, Pages 399-407

  Wu, Yang Chang ^a,b   Sureshbabu, Munisamy ^c   Fang, Yao Ching ^c   Wu, Yi Hsiu ^c   Lan, Yu Hsuan ^b   Chang, Fang Rong ^a   Chang, Ya Wen ^c   Hwang, Tsong Long ^c,d  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^d CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Bractelactone; Calcium; Elastase; Fissistigma bracteolatum; Neutrophils; Superoxide anion

Indexed keywords

ANTIINFLAMMATORY AGENT; BRACTELACTONE; CD11B ANTIGEN; CHALCONE; CYCLIC AMP; ELASTASE; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; THAPSIGARGIN; UNCLASSIFIED DRUG;

ANNONACEAE; ANTIGEN EXPRESSION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHEMICAL STRUCTURE; DRUG ISOLATION; DRUG SYNTHESIS; EXTRACELLULAR CALCIUM; FISSISTIGMA BRACTEOLATUM; HUMAN; HUMAN CELL; LEUKOCYTE ACTIVATION; MEDICINAL PLANT; PROTEIN PHOSPHORYLATION; THIN LAYER CHROMATOGRAPHY;

ADULT; ANNONACEAE; ANTI-INFLAMMATORY AGENTS; ANTIGENS, CD11B; CALCIUM SIGNALING; CHALCONES; HUMANS; IMMUNOBLOTTING; INHIBITORY CONCENTRATION 50; LEUKOCYTES, MONONUCLEAR; MITOGEN-ACTIVATED PROTEIN KINASES; NEUTROPHIL ACTIVATION; NEUTROPHILS; PANCREATIC ELASTASE; PHOSPHORYLATION; PLANT STEMS; REACTIVE OXYGEN SPECIES; SUPEROXIDES; YOUNG ADULT;

FISSISTIGMA BRACTEOLATUM;

EID: 84871875351     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.11.021     Document Type: Article

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