Orai1 regulates intracellular calcium, arrest, and shape polarization during neutrophil recruitment in shear flow

Blood

Volumn 115, Issue 3, 2010, Pages 657-666

  Schaff, Ulrich Y ^a   Dixit, Neha ^a   Procyk, Emily ^a   Yamayoshi, Itsukyo ^a   Tse, Tiffany ^a   Simon, Scott I ^a  

^a University of California   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; CALCIUM; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 1; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1; PHOSPHOLIPASE C; SMALL INTERFERING RNA; CALCIUM CHANNEL; ORAI1 PROTEIN, HUMAN;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL CYCLE ARREST; CELL POLARITY; CELL SHAPE; CELL STRAIN HL 60; CONTROLLED STUDY; HUMAN; KNOCKOUT MOUSE; MOUSE; NEUTROPHIL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SHEAR FLOW; ANIMAL; CELL CULTURE; CELL MOTION; CELL PROLIFERATION; CIRCULATION; GENETICS; INFLAMMATION; INSTITUTE FOR CANCER RESEARCH MOUSE; INTRACELLULAR SPACE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SHEAR STRENGTH; TRANSGENIC MOUSE;

ANIMALS; BLOOD CIRCULATION; CALCIUM; CALCIUM CHANNELS; CELL MOVEMENT; CELL POLARITY; CELL PROLIFERATION; CELL SHAPE; CELLS, CULTURED; HL-60 CELLS; HUMANS; INFLAMMATION; INTRACELLULAR SPACE; MICE; MICE, INBRED ICR; MICE, TRANSGENIC; NEUTROPHILS; SHEAR STRENGTH;

EID: 77449102708     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-05-224659     Document Type: Article

References (56)

1. Roos J, DiGregorio PJ, Yeromin AV, et al. STIM1, an essential and conserved component of storeoperated Ca2+ channel function. J Cell Biol. 2005;169(3):435-445. (Pubitemid 40686694)
2. Zhang SL, Yu Y, Roos J, et al. STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane. Nature. 2005;437(7060):902-905. (Pubitemid 41486767)
3. Feske S, Gwack Y, Prakriya M, et al. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature. 2006;441(7090): 179-185.
4. Soboloff J, Spassova MA, Tang XD, Hewavitharana T, XuW, Gill DL. Orai1 and STIM reconstitute store-operated calcium channel function. J Biol Chem. 2006;281(30):20661-20665. (Pubitemid 44115407)
5. Gwack Y, Srikanth S, Oh-Hora M, et al. Hair loss and defective T- and B-cell function in mice lacking ORAI1. Mol Cell Biol. 2008;28(17):5209-5222.
6. Hoth M, Penner R. Depletion of intracellular calcium stores activates a calcium current in mast cells. Nature. 1992;355(6358):353-356.
7. Bréchard S, Melchior C, Plancon S, Schenten V, Tschirhart EJ. Store-operated Ca(2+) channels formed by TRPC1, TRPC6 and Orai1 and non-storeoperated channels formed by TRPC3 are involved in the regulation of NADPH oxidase in HL-60 granulocytes. Cell Calcium. 2008;44(5):492-506.
8. McMeekin SR, Dransfield I, Rossi AG, Haslett C, Walker TR. E-selectin permits communication between PAF receptors and TRPC channels in human neutrophils. Blood. 2006;107(12):4938-4945. (Pubitemid 43882648)
9. Heiner I, Eisfeld J, Halaszovich CR, et al. Expression profile of the transient receptor potential (TRP) family in neutrophil granulocytes: evidence for currents through long TRP channel 2 induced by ADP-ribose and NAD. Biochem J. 2003; 371(3):1045-1053. (Pubitemid 36578904)
10. Itagaki K, Kannan KB, Singh BB, Hauser CJ. Cytoskeletal reorganization internalizes multiple transient receptor potential channels and blocks calcium entry into human neutrophils. J Immunol. 2004;172(1):601-607. (Pubitemid 38020518)
11. Krause KH, Campbell KP, Welsh MJ, Lew DP. The calcium signal and neutrophil activation. Clin Biochem. 1990;23(2):159-166.
12. Granfeldt D, Samuelsson M, Karlsson A. Capacitative Ca2+ influx and activation of the neutrophil respiratory burst: different regulation of plasma membrane- and granule-localized NADPH-oxidase. J Leukoc Biol. 2002;71(4):611-617.
13. Demaurex N, Monod A, Lew DP, Krause KH. Characterization of receptor-mediated and store-regulated Ca2+ influx in human neutrophils. Biochem J. 1994;297(3):595-601. (Pubitemid 24056116)
14. Sengeløv H, Kjeldsen L, Diamond MS, Springer TA, Borregaard N. Subcellular localization and dynamics of Mac-1 (alpha m beta 2) in human neutrophils. J Clin Invest. 1993;92(3):1467-1476.
15. Ding ZM, Babensee JE, Simon SI, et al. Relative contribution of LFA-1 and Mac-1 to neutrophil adhesion and migration. J Immunol. 1999;163(9): 5029-5038.
16. Solovjov DA, Pluskota E, Plow EF. Distinct roles for the alpha and beta subunits in the functions of integrin alphaMbeta2. J Biol Chem. 2005;280(2): 1336-1345.
17. Zigmond SH, Slonczewski JL, Wilde MW, Carson M. Polymorphonuclear leukocyte locomotion is insensitive to lowered cytoplasmic calcium levels. Cell Motil Cytoskeleton. 1988;9(2):184-189.
18. Jaconi ME, Theler JM, Schlegel W, Appel RD, Wright SD, Lew PD. Multiple elevations of cytosolic-free Ca2+ in human neutrophils: initiation by adherence receptors of the integrin family. J Cell Biol. 1991;112(6):1249-1257.
19. Bengtsson T, Jaconi ME, Gustafson M, et al. Actin dynamics in human neutrophils during adhesion and phagocytosis is controlled by changes in intracellular free calcium. Eur J Cell Biol. 1993;62(1):49-58.
20. Downey GP, Chan CK, Trudel S, Grinstein S. Actin assembly in electropermeabilized neutrophils: role of intracellular calcium. J Cell Biol. 1990; 110(6):1975-1982.
21. Dewitt S, Hallett MB. Cytosolic free Ca(2+) changes and calpain activation are required for beta integrin-accelerated phagocytosis by human neutrophils. J Cell Biol. 2002;159(1):181-189. (Pubitemid 35191529)
22. Kruskal BA, Shak S, Maxfield FR. Spreading of human neutrophils is immediately preceded by a large increase in cytoplasmic free calcium. Proc Natl Acad Sci U S A. 1986;83(9):2919-2923.
23. Pettit EJ, Hallett MB. Release of 'caged' cytosolic Ca2+ triggers rapid spreading of human neutrophils adherent via integrin engagement. J Cell Sci. 1998;111(15):2209-2215.
24. Lawson MA, Maxfield FR. Ca(2+)- and calcineurindependent recycling of an integrin to the front of migrating neutrophils. Nature. 1995;377(6544):75-79.
25. Eddy RJ, Pierini LM, Matsumura F, Maxfield FR. Ca2+-dependent myosin II activation is required for uropod retraction during neutrophil migration. J Cell Sci. 2000;113(7):1287-1298. (Pubitemid 30229545)
26. Cinamon G, Grabovsky V, Winter E, et al. Novel chemokine functions in lymphocyte migration through vascular endothelium under shear flow. J Leukoc Biol. 2001;69(6):860-866. (Pubitemid 32577884)
27. Cinamon G, Shinder V, Shamri R, Alon R. Chemoattractant signals and beta 2 integrin occupancy at apical endothelial contacts combine with shear stress signals to promote transendothelial neutrophil migration. J Immunol. 2004;173(12):7282-7291. (Pubitemid 39628165)
28. Green CE, Schaff UY, Sarantos MR, Lum AF, Staunton DE, Simon SI. Dynamic shifts in LFA-1 affinity regulate neutrophil rolling, arrest, and transmigration on inflamed endothelium. Blood. 2006;107(5):2101-2111.
29. Schaff UY, Yamayoshi I, Tse T, Griffin D, Kibathi L, Simon SI. Calcium flux in neutrophils synchronizes beta2 integrin adhesive and signaling events that guide inflammatory recruitment. Ann Biomed Eng. 2008;36(4):632-646.
30. Kogan TP, Revelle BM, Tapp S, Scott D, Beck PJ. A single amino acid residue can determine the ligand specificity of E-selectin. J Biol Chem. 1995;270(23):14047-14055.
31. Schaff UY, Xing MM, Lin KK, Pan N, Jeon NL, Simon SI. Vascular mimetics based on microfluidics for imaging the leukocyte-endothelial inflammatory response. Lab Chip. 2007;7(4):448-456. (Pubitemid 46496555)
32. Simon SI, Hu Y, Vestweber D, Smith CW. Neutrophil tethering on E-selectin activates beta 2 integrin binding to ICAM-1 through a mitogenactivated protein kinase signal transduction pathway. J Immunol. 2000;164(8):4348-4358. (Pubitemid 30215098)
33. Gwack Y, Feske S, Srikanth S, Hogan PG, Rao A. Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes. Cell Calcium. 2007;42(2):145-156. (Pubitemid 47029605)
34. Lowell CA, Fumagalli L, Berton G. Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions. J Cell Biol. 1996;133(4):895-910. (Pubitemid 26160989)
35. Bootman MD, Collins TJ, Mackenzie L, Roderick HL, Berridge MJ, Peppiatt CM. 2-aminoethoxydiphenyl borate (2-APB) is a reliable blocker of store-operated Ca2+ entry but an inconsistent inhibitor of InsP3-induced Ca2+ release. FASEB J. 2002;16(10):1145-1150.
36. Zhang H, Schaff UY, Green CE, et al. Impaired integrin-dependent function in Wiskott-Aldrich syndrome protein-deficient murine and human neutrophils. Immunity. 2006;25(2):285-295. (Pubitemid 44224148)
37. Prakriya M, Lewis RS. Potentiation and inhibition of Ca(2+) release-activated Ca(2+) channels by 2-aminoethyldiphenyl borate (2-APB) occurs independently of IP(3) receptors. J Physiol. 2001; 536(1):3-19. (Pubitemid 32952214)
38. Simon SI, Green CE. Molecular mechanics and dynamics of leukocyte recruitment during inflammation. Annu Rev Biomed Eng. 2005;7:151-185. (Pubitemid 41170187)
39. Zarbock A, Lowell CA, Ley K. Spleen tyrosine kinase Syk is necessary for E-selectin-induced alpha (L)beta(2) integrin-mediated rolling on intercellular adhesion molecule-1. Immunity. 2007;26(6):773-783. (Pubitemid 46907666)
40. Ng-Sikorski J, Andersson R, Patarroyo M, Andersson T. Calcium signaling capacity of the CD11b/CD18 integrin on human neutrophils. Exp Cell Res. 1991;195(2):504-508.
41. Schorr W, Swandulla D, Zeilhofer HU. Mechanisms of IL-8-induced Ca2+ signaling in human neutrophil granulocytes. Eur J Immunol. 1999; 29(3):897-904. (Pubitemid 29119069)
42. Petersen M, Williams JD, Hallett MB. Crosslinking of CD11b or CD18 signals release of localized Ca2+ from intracellular stores in neutrophils. Immunology. 1993;80(1):157-159.
43. Feske S. ORAI1 and STIM1 deficiency in human and mice: roles of store-operated Ca2+ entry in the immune system and beyond. Immunol Rev. 2009;231(1):189-209.
44. Sjaastad MD, Lewis RS, Nelson WJ. Mechanisms of integrin-mediated calcium signaling in MDCK cells: regulation of adhesion by IP3- and store-independent calcium influx. Mol Biol Cell. 1996;7(7):1025-1041.
45. Smyth JT, Dehaven WI, Bird GS, Putney JW Jr. Ca2+-store-dependent and -independent reversal of Stim1 localization and function. J Cell Sci. 2008;121(6):762-772.
46. Brandman O, Liou J, Park WS, Meyer T. STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels. Cell. 2007;131(7):1327-1339. (Pubitemid 350297421)
47. Lioudyno MI, Kozak JA, Penna A, et al. Orai1 and STIM1 move to the immunological synapse and are up-regulated during T cell activation. Proc Natl Acad Sci U S A. 2008;105(6):2011-2016.
48. Hellberg C, Molony L, Zheng L, Andersson T. Ca2+ signalling mechanisms of the beta 2 integrin on neutrophils: involvement of phospholipase C gamma 2 and Ins(1,4,5)P3. Biochem J. 1996; 317(Pt 2):403-409.
49. Kanner SB, Grosmaire LS, Ledbetter JA, Damle NK. Beta 2-integrin LFA-1 signaling through phospholipase C-gamma 1 activation. Proc Natl Acad Sci U S A. 1993;90(15):7099-7103.
50. Pasvolsky R, Feigelson SW, Kilic SS, et al. A LAD-III syndrome is associated with defective expression of the Rap-1 activator CalDAG-GEFI in lymphocytes, neutrophils, and platelets. J Exp Med. 2007;204(7):1571-1582. (Pubitemid 47048024)
51. Eierman D, Hellberg C, Sjolander A, Andersson T. Chemotactic factor receptor activation transiently impairs the Ca2+ signaling capacity of beta 2 integrins on human neutrophils. Exp Cell Res. 1994;215(1):90-96. (Pubitemid 24339178)
52. Pettit EJ, Hallett MB. Two distinct Ca2+ storage and release sites in human neutrophils. J Leukoc Biol. 1998;63(2):225-232.
53. Chandy KG, Wulff H, Beeton C, Pennington M, Gutman GA, Cahalan MD. K+ channels as targets for specific immunomodulation. Trends Pharmacol Sci. 2004;25(5):280-289.
54. Fanger CM, Rauer H, Neben AL, et al. Calciumactivated potassium channels sustain calcium signaling in T lymphocytes: selective blockers and manipulated channel expression levels. J Biol Chem. 2001;276(15):12249-12256. (Pubitemid 37385394)
55. DeHaven WI, Smyth JT, Boyles RR, Bird GS, Putney JW Jr. Complex actions of 2-aminoethyldiphenyl borate on store-operated calcium entry. J Biol Chem. 2008;283(28):19265-19273.
56. Kelher MR, Ambruso DR, Elzi DJ, et al. Formyl-Met-Leu-Phe induces calcium-dependent tyrosine phosphorylation of Rel-1 in neutrophils. Cell Calcium. 2003;34(6):445-455.