Neutrophils in rheumatoid arthritis: More than simple final effectors

Autoimmunity Reviews

Volumn 9, Issue 8, 2010, Pages 531-535

  Cascao R ^a   Rosario H S ^a   Souto Carneiro, M M ^b   Fonseca, J E ^a,c  

^a INSTITUTO DE MEDICINA MOLECULAR JOÃO LOBO ANTUNES   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c HOSPITAL DE SANTA MARIA   (Portugal)

Author keywords

Apoptosis; Etiopathology; Immune mediators; Neutrophils; Rheumatoid arthritis; ROS

Indexed keywords

B CELL ACTIVATING FACTOR; DISEASE MODIFYING ANTIRHEUMATIC DRUG; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; ONCOSTATIN M; OSTEOCLAST DIFFERENTIATION FACTOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR INHIBITOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

ANTIGEN PRESENTING CELL; APOPTOSIS; BONE EROSION; BONE REMODELING; CHRONIC INFLAMMATION; CYTOKINE PRODUCTION; HUMAN; HYPOXIA; IMMUNOMODULATION; LEUKOCYTE ACTIVATION; LEUKOCYTE MIGRATION; LYMPHOCYTIC INFILTRATION; NEUTROPHIL; NONHUMAN; OSTEOCLAST; RESPIRATORY BURST; REVIEW; RHEUMATOID ARTHRITIS;

ANIMALS; ARTHRITIS, RHEUMATOID; HUMANS; NEUTROPHILS;

EID: 77952742498     PISSN: 15689972     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autrev.2009.12.013     Document Type: Review

References (40)

1. Nathan C. Neutrophils and immunity: challenges and opportunities. Nat Rev Immunol 6 (2006) 173-182
2. Ashcroft G.S., Lei K., Jin W., Longenecker G., Kulkarni A.B., Greenwell-Wild T., et al. Secretory leukocyte protease inhibitor mediates non-redundant functions necessary for normal wound healing. Nat Med 6 (2000) 1147-1153
3. Cross A., Edwards S.W., Bucknall R.C., and Moots R.J. Secretion of oncostatin M by neutrophils in rheumatoid arthritis. Arthritis Rheum 50 (2004) 1430-1436
4. Auer J., Blass M., Schulze-Koops H., Russwurm S., Nagel T., Kalden J.R., et al. Expression and regulation of CCL18 in synovial fluid neutrophils of patients with rheumatoid arthritis. Arthritis Res Ther 9 (2007) R94
5. Kasama T., Kobayashi K., Yajima N., Shiozawa F., Yoda Y., Takeuchi H.T., et al. Expression of vascular endothelial growth factor by synovial fluid neutrophils in rheumatoid arthritis (RA). Clin Exp Immunol 121 (2000) 533-538
6. Cheema G.S., Roschke V., Hilbert D.M., and Stohl W. Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases. Arthritis Rheum 44 (2001) 1313-1319
7. Scapini P., Carletto A., Nardelli B., Calzetti F., Roschke V., Merigo F., et al. Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases. Blood 105 (2005) 830-837
8. Assi L.K., Wong S.H., Ludwig A., Raza K., Gordon C., Salmon M., et al. Tumor necrosis factor alpha activates release of B lymphocyte stimulator by neutrophils infiltrating the rheumatoid joint. Arthritis Rheum 56 (2007) 1776-1786
9. Vossenaar E.R., Nijenhuis S., Helsen M.M., van der Heijden A., Senshu T., van den Berg W.B., et al. Citrullination of synovial proteins in murine models of rheumatoid arthritis. Arthritis Rheum 48 (2003) 2489-2500
10. Eyles J.L., Roberts A.W., Metcalf D., and Wicks I.P. Granulocyte colony-stimulating factor and neutrophils-forgotten mediators of inflammatory disease. Nat Clin Pract Rheumatol 2 (2006) 500-510
11. Anzilotti C., Pratesi F., Tommasi C., and Migliorini P. Peptidylarginine deiminase 4 and citrullination in health and disease. Autoimmun Rev 9 3 (2010) 158-160
12. Hoshino A., Nagao T., Nagi-Miura N., Ohno N., Yasuhara M., Yamamoto K., et al. MPO-ANCA induces IL-17 production by activated neutrophils in vitro via classical complement pathway-dependent manner. J Autoimmun 31 (2008) 79-89
13. Bjorkman L., Dahlgren C., Karlsson A., Brown K.L., and Bylund J. Phagocyte-derived reactive oxygen species as suppressors of inflammatory disease. Arthritis Rheum 58 (2008) 2931-2935
14. Hultqvist M., and Holmdahl R. Ncf1 (p47phox) polymorphism determines oxidative burst and the severity of arthritis in rats and mice. Cell Immunol 233 (2005) 97-101
15. Bylund J., MacDonald K.L., Brown K.L., Mydel P., Collins L.V., Hancock R.E., et al. Enhanced inflammatory responses of chronic granulomatous disease leukocytes involve ROS-independent activation of NF-kappa B. Eur J Immunol 37 (2007) 1087-1096
16. Kitas G.D., Salmon M., Farr M., Young S.P., and Bacon P.A. T-cell functional defects in rheumatoid arthritis: intrinsic or extrinsic?. J Autoimmun 1 (1988) 339-351
17. Cedergren J., Forslund T., Sundqvist T., and Skogh T. Intracellular oxidative activation in synovial fluid neutrophils from patients with rheumatoid arthritis but not from other arthritis patients. J Rheumatol 34 (2007) 2162-2170
18. Robinson J.J., Watson F., Bucknall R.C., and Edwards S.W. Stimulation of neutrophils by insoluble immunoglobulin aggregates from synovial fluid of patients with rheumatoid arthritis. Eur J Clin Invest 22 (1992) 314-318
19. Krumbholz M., Specks U., Wick M., Kalled S.L., Jenne D., and Meinl E. BAFF is elevated in serum of patients with Wegener's granulomatosis. J Autoimmun 25 (2005) 298-302
20. Bostan M., Brasoveanu L.I., Livescu A., Manda G., Neagu M., and Iordachescu D. Effects of synovial fluid on the respiratory burst of granulocytes in rheumatoid arthritis. J Cell Mol Med 5 (2001) 188-194
21. Akgul C., Moulding D.A., and Edwards S.W. Molecular control of neutrophil apoptosis. FEBS Lett 487 (2001) 318-322
22. Sweeney S.E., and Firestein G.S. Rheumatoid arthritis: regulation of synovial inflammation. Int J Biochem Cell Biol 36 (2004) 372-378
23. Andersson A.K., Li C., and Brennan F.M. Recent developments in the immunobiology of rheumatoid arthritis. Arthritis Res Ther 10 (2008) 204
24. Weinmann P., Moura R.A., Caetano-Lopes J.R., Pereira P.A., Canhao H., Queiroz M.V., et al. Delayed neutrophil apoptosis in very early rheumatoid arthritis patients is abrogated by methotrexate therapy. Clin Exp Rheumatol 25 (2007) 885-887
25. Raza K., Scheel-Toellner D., Lee C.Y., Pilling D., Curnow S.J., Falciani F., et al. Synovial fluid leukocyte apoptosis is inhibited in patients with very early rheumatoid arthritis. Arthritis Res Ther 8 (2006) R120
26. Mangan P.R., Harrington L.E., O'Quinn D.B., Helms W.S., Bullard D.C., Elson C.O., et al. Transforming growth factor-beta induces development of the T(H)17 lineage. Nature 441 (2006) 231-234
27. Miranda-Carus M.E., Benito-Miguel M., Balsa A., Cobo-Ibanez T., Perez de Ayala C., Pascual-Salcedo D., et al. Peripheral blood T lymphocytes from patients with early rheumatoid arthritis express RANKL and interleukin-15 on the cell surface and promote osteoclastogenesis in autologous monocytes. Arthritis Rheum 54 (2006) 1151-1164
28. Rouse B.T. Regulatory T cells in health and disease. J Intern Med 262 (2007) 78-95
29. Renshaw S.A., Timmons S.J., Eaton V., Usher L.R., Akil M., Bingle C.D., et al. Inflammatory neutrophils retain susceptibility to apoptosis mediated via the Fas death receptor. J Leukoc Biol 67 (2000) 662-668
30. Kiener P.A., Davis P.M., Rankin B.M., Klebanoff S.J., Ledbetter J.A., Starling G.C., et al. Human monocytic cells contain high levels of intracellular Fas ligand: rapid release following cellular activation. J Immunol 159 (1997) 1594-1598
31. Hasunuma T., Kayagaki N., Asahara H., Motokawa S., Kobata T., Yagita H., et al. Accumulation of soluble Fas in inflamed joints of patients with rheumatoid arthritis. Arthritis Rheum 40 (1997) 80-86
32. Bell A.L., Magill M.K., McKane R., and Irvine A.E. Human blood and synovial fluid neutrophils cultured in vitro undergo programmed cell death which is promoted by the addition of synovial fluid. Ann Rheum Dis 54 (1995) 910-915
33. Parsonage G., Filer A., Bik M., Hardie D., Lax S., Howlett K., et al. Prolonged, granulocyte-macrophage colony-stimulating factor-dependent, neutrophil survival following rheumatoid synovial fibroblast activation by IL-17 and TNFalpha. Arthritis Res Ther 10 (2008) R47
34. Cross A., Barnes T., Bucknall R.C., Edwards S.W., and Moots R.J. Neutrophil apoptosis in rheumatoid arthritis is regulated by local oxygen tensions within joints. J Leukoc Biol 80 (2006) 521-528
35. Wong S.H., Francis N., Chahal H., Raza K., Salmon M., Scheel-Toellner D., et al. Lactoferrin is a survival factor for neutrophils in rheumatoid synovial fluid. Rheumatology (Oxford) 48 (2009) 39-44
36. Iking-Konert C., Ostendorf B., Sander O., Jost M., Wagner C., Joosten L., et al. Transdifferentiation of polymorphonuclear neutrophils to dendritic-like cells at the site of inflammation in rheumatoid arthritis: evidence for activation by T cells. Ann Rheum Dis 64 (2005) 1436-1442
37. Iking-Konert C., Wagner C., Denefleh B., Hug F., Schneider M., Andrassy K., et al. Up-regulation of the dendritic cell marker CD83 on polymorphonuclear neutrophils (PMN): divergent expression in acute bacterial infections and chronic inflammatory disease. Clin Exp Immunol 130 (2002) 501-508
38. Ziolkowska M., Kurowska M., Radzikowska A., Luszczykiewicz G., Wiland P., Dziewczopolski W., et al. High levels of osteoprotegerin and soluble receptor activator of nuclear factor kappa B ligand in serum of rheumatoid arthritis patients and their normalization after anti-tumor necrosis factor alpha treatment. Arthritis Rheum 46 (2002) 1744-1753
39. Pettit A.R., Ji H., von Stechow D., Muller R., Goldring S.R., Choi Y., et al. TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis. Am J Pathol 159 (2001) 1689-1699
40. Poubelle P.E., Chakravarti A., Fernandes M.J., Doiron K., and Marceau A.A. Differential expression of RANK, RANK-L, and osteoprotegerin by synovial fluid neutrophils from patients with rheumatoid arthritis and by healthy human blood neutrophils. Arthritis Res Ther 9 (2007) R25