A pilot study of cerebral and haemodynamic physiological changes during sedation with dexmedetomidine or propofol in patients with acute brain injury

Anaesthesia and Intensive Care

Volumn 40, Issue 6, 2012, Pages 949-957

  James, M L ^a   Olson, D M ^a,b   Graffagnino, C ^a,b  

^a DUKE UNIVERSITY HOSPITAL   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acute brain injury; Clinical trial; Dexmedetomidine; Human; Microdialysis; Neurocritical care; Propofol; Sedation

Indexed keywords

DEXMEDETOMIDINE; PROPOFOL; HYPNOTIC SEDATIVE AGENT; LACTIC ACID; PYRUVIC ACID;

ADULT; ARTICLE; ARTIFICIAL VENTILATION; BRAIN HEMORRHAGE; BRAIN INJURY; BRAIN METABOLISM; CLINICAL ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; HEMODYNAMIC MONITORING; HEMODYNAMIC PARAMETERS; HUMAN; PHASE 4 CLINICAL TRIAL; RANDOMIZED CONTROLLED TRIAL; SEDATION; SUBARACHNOID HEMORRHAGE; ANESTHESIA LEVEL; BODY TEMPERATURE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; GLASGOW COMA SCALE; INJURY SCALE; INTRACRANIAL PRESSURE; METABOLISM; MICRODIALYSIS; OXIMETRY; PATHOPHYSIOLOGY; PILOT STUDY; PROSPECTIVE STUDY;

BODY TEMPERATURE; BRAIN INJURIES; CONSCIOUSNESS MONITORS; CROSS-OVER STUDIES; DEXMEDETOMIDINE; GLASGOW COMA SCALE; HUMANS; HYPNOTICS AND SEDATIVES; INTRACRANIAL PRESSURE; LACTIC ACID; MICRODIALYSIS; OXIMETRY; PILOT PROJECTS; PROPOFOL; PROSPECTIVE STUDIES; PYRUVIC ACID; RESPIRATION, ARTIFICIAL; TRAUMA SEVERITY INDICES;

EID: 84871871087     PISSN: 0310057X     EISSN: 14480271     Source Type: Journal    
DOI: 10.1177/0310057x1204000605     Document Type: Article

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