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Volumn 112, Issue 5, 2011, Pages 1212-1217

The effects of perioperative and intensive care unit sedation on brain organ dysfunction

Author keywords

[No Author keywords available]

Indexed keywords

SEDATIVE AGENT; ANALGESIC AGENT; ANESTHETIC AGENT; HYPNOTIC SEDATIVE AGENT;

EID: 79955476512     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ANE.0b013e318215366d     Document Type: Review
Times cited : (29)

References (85)
  • 1
    • 0004235298 scopus 로고    scopus 로고
    • American Psychiatric Association 4th ed., text rev. Washington, DC: American Psychiatric Association
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th ed., text rev. Washington, DC: American Psychiatric Association, 2000
    • (2000) Diagnostic and Statistical Manual of Mental Disorders
  • 2
    • 0034908863 scopus 로고    scopus 로고
    • Delirium in the intensive care unit: An under-recognized syndrome of organ dysfunction
    • DOI 10.1055/s-2001-13826
    • Ely EW, Siegel MD, Inouye SK. Delirium in the intensive care unit: an under-recognized syndrome of organ dysfunction. Semin Respir Crit Care Med 2001;22:115-26 (Pubitemid 32729506)
    • (2001) Seminars in Respiratory and Critical Care Medicine , vol.22 , Issue.2 , pp. 115-126
    • Ely, E.W.1    Siegel, M.D.2    Inouye, S.K.3
  • 8
    • 64649084172 scopus 로고    scopus 로고
    • The long-term cognitive and functional outcomes of postoperative delirium after cardiac surgery
    • Koster S, Hensens AG, van der PJ. The long-term cognitive and functional outcomes of postoperative delirium after cardiac surgery. Ann Thorac Surg 2009;87:1469-74
    • (2009) Ann Thorac Surg , vol.87 , pp. 1469-1474
    • Koster, S.1    Hensens, A.G.2    Van Der, P.J.3
  • 13
    • 33846296223 scopus 로고    scopus 로고
    • Incidence, risk factors and consequences of ICU delirium
    • DOI 10.1007/s00134-006-0399-8
    • Ouimet S, Kavanagh BP, Gottfried SB, Skrobik Y. Incidence, risk factors and consequences of ICU delirium. Intensive Care Med 2007;33:66-73 (Pubitemid 46115471)
    • (2007) Intensive Care Medicine , vol.33 , Issue.1 , pp. 66-73
    • Ouimet, S.1    Kavanagh, B.P.2    Gottfried, S.B.3    Skrobik, Y.4
  • 17
    • 77249165024 scopus 로고    scopus 로고
    • Association between acute care and critical illness hospitalization and cognitive function in older adults
    • Ehlenbach WJ, Hough CL, Crane PK, Haneuse S, Carson SS, Curtis RJ, Larson EB. Association between acute care and critical illness hospitalization and cognitive function in older adults. JAMA 2010;303:763-70
    • (2010) JAMA , vol.303 , pp. 763-770
    • Ehlenbach, W.J.1    Hough, C.L.2    Crane, P.K.3    Haneuse, S.4    Carson, S.S.5    Curtis, R.J.6    Larson, E.B.7
  • 18
    • 78049351929 scopus 로고    scopus 로고
    • Long-term cognitive impairment and functional disability among survivors of severe sepsis
    • Iwashyna TJ, Ely EW, Smith DS, Langa KM. Long-term cognitive impairment and functional disability among survivors of severe sepsis. JAMA 2010;304:1787-94
    • (2010) JAMA , vol.304 , pp. 1787-1794
    • Iwashyna, T.J.1    Ely, E.W.2    Smith, D.S.3    Langa, K.M.4
  • 22
    • 0034891470 scopus 로고    scopus 로고
    • Delirium in an intensive care unit: A study of risk factors
    • DOI 10.1007/s001340101017
    • Dubois MJ, Bergeron N, Dumont M, Dial S, Skrobik Y. Delirium in an intensive care unit: a study of risk factors. Intensive Care Med 2001;27:1297-304 (Pubitemid 32758927)
    • (2001) Intensive Care Medicine , vol.27 , Issue.8 , pp. 1297-1304
    • Dubois, M.-J.1    Bergeron, N.2    Dumont, M.3    Dial, S.4    Skrobik, Y.5
  • 24
    • 0032211485 scopus 로고    scopus 로고
    • The association of intraoperative factors with the development of postoperative delirium
    • DOI 10.1016/S0002-9343(98)00292-7, PII S0002934398002927
    • Marcantonio ER, Goldman L, Orav EJ, Cook EF, Lee TH. The association of intraoperative factors with the development of postoperative delirium. Am J Med 1998;105:380-4 (Pubitemid 28536222)
    • (1998) American Journal of Medicine , vol.105 , Issue.5 , pp. 380-384
    • Marcantonio, E.R.1    Goldman, L.2    Orav, E.J.3    Cook, E.F.4    Thomas H, L.5
  • 26
    • 1442289922 scopus 로고    scopus 로고
    • Posttraumatic stress disorder and health-related quality of life in long-term survivors of acute respiratory distress syndrome
    • DOI 10.1176/appi.ajp.161.1.45
    • Kapfhammer HP, Rothenhausler HB, Krauseneck T, Stoll C, Schelling G. Posttraumatic stress disorder and health-related quality of life in long-term survivors of acute respiratory distress syndrome. Am J Psychiatry 2004;161:45-52 (Pubitemid 38419306)
    • (2004) American Journal of Psychiatry , vol.161 , Issue.1 , pp. 45-52
    • Kapfhammer, H.P.1    Rothenhausler, H.B.2    Krauseneck, T.3    Stoll, C.4    Schelling, G.5
  • 30
  • 35
    • 77949296405 scopus 로고    scopus 로고
    • The effect of bispectral index monitoring on long-term survival in the B-aware trial
    • Leslie K, Myles PS, Forbes A, Chan MT. The effect of bispectral index monitoring on long-term survival in the B-aware trial. Anesth Analg 2010;110:816-22
    • (2010) Anesth Analg , vol.110 , pp. 816-822
    • Leslie, K.1    Myles, P.S.2    Forbes, A.3    Chan, M.T.4
  • 36
  • 37
    • 2542562742 scopus 로고    scopus 로고
    • Bispectral index monitoring to prevent awareness during anaesthesia: The B-Aware randomised controlled trial
    • DOI 10.1016/S0140-6736(04)16300-9, PII S0140673604163009
    • Myles PS, Leslie K, McNeil J, Forbes A, Chan MT. Bispectral index monitoring to prevent awareness during anaesthesia: the B-Aware randomised controlled trial. Lancet 2004;363:1757-63 (Pubitemid 38698378)
    • (2004) Lancet , vol.363 , Issue.9423 , pp. 1757-1763
    • Myles, P.S.1    Leslie, K.2    McNeil, J.3    Forbes, A.4    Chan, M.T.V.5
  • 38
    • 69549113041 scopus 로고    scopus 로고
    • Preserved memory function during bispectral index-guided anesthesia with sevoflurane for major orthopedic surgery
    • Kerssens C, Gaither JR, Sebel PS. Preserved memory function during bispectral index-guided anesthesia with sevoflurane for major orthopedic surgery. Anesthesiology 2009;111:518-24
    • (2009) Anesthesiology , vol.111 , pp. 518-524
    • Kerssens, C.1    Gaither, J.R.2    Sebel, P.S.3
  • 39
    • 33749044652 scopus 로고    scopus 로고
    • Is depth of anesthesia, as assessed by the Bispectral Index, related to postoperative cognitive dysfunction and recovery?
    • DOI 10.1213/01.ane.0000228870.48028.b5, PII 0000053920060900000020
    • Farag E, Chelune GJ, Schubert A, Mascha EJ. Is depth of anesthesia, as assessed by the bispectral index, related to postoperative cognitive dysfunction and recovery? Anesth Analg 2006;103:633-40 (Pubitemid 44542916)
    • (2006) Anesthesia and Analgesia , vol.103 , Issue.3 , pp. 633-640
    • Farag, E.1    Chelune, G.J.2    Schubert, A.3    Mascha, E.J.4
  • 40
    • 10944222205 scopus 로고    scopus 로고
    • Anesthetic management and one-year mortality after noncardiac surgery
    • DOI 10.1213/01.ANE.0000147519.82841.5E
    • Monk TG, Saini V, Weldon BC, Sigl JC. Anesthetic management and one-year mortality after noncardiac surgery. Anesth Analg 2005;100:4-10 (Pubitemid 40013594)
    • (2005) Anesthesia and Analgesia , vol.100 , Issue.1 , pp. 4-10
    • Monk, T.G.1    Saini, V.2    Weldon, B.C.3    Sigl, J.C.4
  • 41
    • 59649090562 scopus 로고    scopus 로고
    • Mortality within 2 years after surgery in relation to low intraoperative bispectral index values and preexisting malignant disease
    • Lindholm ML, Traff S, Granath F, Greenwald SD, Ekbom A, Lennmarken C, Sandin RH. Mortality within 2 years after surgery in relation to low intraoperative bispectral index values and preexisting malignant disease. Anesth Analg 2009;108:508-12
    • (2009) Anesth Analg , vol.108 , pp. 508-512
    • Lindholm, M.L.1    Traff, S.2    Granath, F.3    Greenwald, S.D.4    Ekbom, A.5    Lennmarken, C.6    Sandin, R.H.7
  • 42
    • 73649119569 scopus 로고    scopus 로고
    • Sedation depth during spinal anesthesia and the development of postoperative delirium in elderly patients undergoing hip fracture repair
    • Sieber FE, Zakriya KJ, Gottschalk A, Blute MR, Lee HB, Rosenberg PB, Mears SC. Sedation depth during spinal anesthesia and the development of postoperative delirium in elderly patients undergoing hip fracture repair. Mayo Clin Proc 2010;85:18-26
    • (2010) Mayo Clin Proc , vol.85 , pp. 18-26
    • Sieber, F.E.1    Zakriya, K.J.2    Gottschalk, A.3    Blute, M.R.4    Lee, H.B.5    Rosenberg, P.B.6    Mears, S.C.7
  • 44
    • 33747622051 scopus 로고    scopus 로고
    • Evidence-based clinical update: General anesthesia and the risk of delirium and postoperative cognitive dysfunction [Mise a jour clinique fondee sur des donnees probantes: L'anesthesie generale et le risque de delire et de dysfonctionnement cognitif postoperatoire]
    • Bryson GL, Wyand A. Evidence-based clinical update: General anesthesia and the risk of delirium and postoperative cognitive dysfunction [Mise a jour clinique fondee sur des donnees probantes: l'anesthesie generale et le risque de delire et de dysfonctionnement cognitif postoperatoire]. Can J Anaesth 2006;53:669-77
    • (2006) Can J Anaesth , vol.53 , pp. 669-677
    • Bryson, G.L.1    Wyand, A.2
  • 45
    • 77954060315 scopus 로고    scopus 로고
    • Design and organization of the dexamethasone, light anesthesia and tight glucose control (DeLiT) trial: A factorial trial evaluating the effects of corticosteroids, glucose control, and depth-of-anesthesia on perioperative inflammation and morbidity from major non-cardiac surgery
    • Abdelmalak B, Maheshwari A, Mascha E, Srivastava S, Marks T, Tang WW, Kurz A, Sessler DI. Design and organization of the dexamethasone, light anesthesia and tight glucose control (DeLiT) trial: a factorial trial evaluating the effects of corticosteroids, glucose control, and depth-of-anesthesia on perioperative inflammation and morbidity from major non-cardiac surgery. BMC Anesthesiol 2010;10:11
    • (2010) BMC Anesthesiol , vol.10 , pp. 11
    • Abdelmalak, B.1    Maheshwari, A.2    Mascha, E.3    Srivastava, S.4    Marks, T.5    Tang, W.W.6    Kurz, A.7    Sessler, D.I.8
  • 46
    • 0031596438 scopus 로고    scopus 로고
    • The use of continuous IV sedation is associated with prolongation of mechanical ventilation
    • Kollef MH, Levy NT, Ahrens TS, Schaiff R, Prentice D, Sherman G. The use of continuous i.v. sedation is associated with prolongation of mechanical ventilation. Chest 1998;114: 541-8 (Pubitemid 28387536)
    • (1998) Chest , vol.114 , Issue.2 , pp. 541-548
    • Kollef, M.H.1    Levy, N.T.2    Ahrens, T.S.3    Schaiff, R.4    Prentice, D.5    Sherman, G.6
  • 47
    • 0034682246 scopus 로고    scopus 로고
    • Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation
    • DOI 10.1056/NEJM200005183422002
    • Kress JP, Pohlman AS, O'Connor MF, Hall JB. Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. N Engl J Med 2000;342:1471-7 (Pubitemid 30318270)
    • (2000) New England Journal of Medicine , vol.342 , Issue.20 , pp. 1471-1477
    • Kress, J.P.1    Pohlman, A.S.2    O'Connor, M.F.3    Hall, J.B.4
  • 48
    • 58149269914 scopus 로고    scopus 로고
    • Presence of electroencephalogram burst suppression in sedated, critically ill patients is associated with increased mortality
    • Watson PL, Shintani AK, Tyson R, Pandharipande PP, Pun BT, Ely EW. Presence of electroencephalogram burst suppression in sedated, critically ill patients is associated with increased mortality. Crit Care Med 2008;36:3171-7
    • (2008) Crit Care Med , vol.36 , pp. 3171-3177
    • Watson, P.L.1    Shintani, A.K.2    Tyson, R.3    Pandharipande, P.P.4    Pun, B.T.5    Ely, E.W.6
  • 49
    • 0037042709 scopus 로고    scopus 로고
    • Quality improvement report: Effect of a scoring system and protocol for sedation on duration of patients' need for ventilator support in a surgical intensive care unit
    • Brattebo G, Hofoss D, Flaatten H, Muri AK, Gjerde S, Plsek PE. Effect of a scoring system and protocol for sedation on duration of patients' need for ventilator support in a surgical intensive care unit. BMJ 2002;324:1386-9 (Pubitemid 34628016)
    • (2002) British Medical Journal , vol.324 , Issue.7350 , pp. 1386-1389
    • Brattebo, G.1    Hofoss, D.2    Flaatten, H.3    Muri, A.K.4    Gjerde, S.5    Plsek, P.E.6
  • 52
    • 75749106589 scopus 로고    scopus 로고
    • A protocol of no sedation for critically ill patients receiving mechanical ventilation: A randomised trial
    • Strom T, Martinussen T, Toft P. A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial. Lancet 2010;375:475-80
    • (2010) Lancet , vol.375 , pp. 475-480
    • Strom, T.1    Martinussen, T.2    Toft, P.3
  • 56
    • 0033678648 scopus 로고    scopus 로고
    • Intensive care unit drug use and subsequent quality of life in acute lung injury patients
    • Nelson BJ, Weinert CR, Bury CL, Marinelli WA, Gross CR. Intensive care unit drug use and subsequent quality of life in acute lung injury patients. Crit Care Med 2000;28:3626-30
    • (2000) Crit Care Med , vol.28 , pp. 3626-3630
    • Nelson, B.J.1    Weinert, C.R.2    Bury, C.L.3    Marinelli, W.A.4    Gross, C.R.5
  • 58
    • 24344437764 scopus 로고    scopus 로고
    • Epidemiology and treatment of psychiatric conditions that develop after critical illness
    • DOI 10.1097/01.ccx.0000168529.23078.64
    • Weinert C. Epidemiology and treatment of psychiatric conditions that develop after critical illness. Curr Opin Crit Care 2005;11:376-80 (Pubitemid 41248313)
    • (2005) Current Opinion in Critical Care , vol.11 , Issue.4 , pp. 376-380
    • Weinert, C.1
  • 59
    • 38149133015 scopus 로고    scopus 로고
    • Post-ICU consequences of patient wakefulness and sedative exposure during mechanical ventilation
    • Weinert CR, Sprenkle M. Post-ICU consequences of patient wakefulness and sedative exposure during mechanical ventilation. Intensive Care Med 2008;34:82-90
    • (2008) Intensive Care Med , vol.34 , pp. 82-90
    • Weinert, C.R.1    Sprenkle, M.2
  • 60
    • 54549116261 scopus 로고    scopus 로고
    • Understanding posttraumatic stress disorder- related symptoms after critical care: The early illness amnesia hypothesis
    • Granja C, Gomes E, Amaro A, Ribeiro O, Jones C, Carneiro A, Costa-Pereira A. Understanding posttraumatic stress disorder- related symptoms after critical care: the early illness amnesia hypothesis. Crit Care Med 2008;36:2801-9
    • (2008) Crit Care Med , vol.36 , pp. 2801-2809
    • Granja, C.1    Gomes, E.2    Amaro, A.3    Ribeiro, O.4    Jones, C.5    Carneiro, A.6    Costa-Pereira, A.7
  • 61
    • 0035107464 scopus 로고    scopus 로고
    • Memory, delusions, and the development of acute posttraumatic stress disorder-related symptoms after intensive care
    • Jones C, Griffiths RD, Humphris G, Skirrow PM. Memory, delusions, and the development of acute posttraumatic stress disorder-related symptoms after intensive care. Crit Care Med 2001;29:573-80 (Pubitemid 32225300)
    • (2001) Critical Care Medicine , vol.29 , Issue.3 , pp. 573-580
    • Jones, C.1    Griffiths, R.D.2    Humphris, G.3    Skirrow, P.M.4
  • 62
    • 34548398881 scopus 로고    scopus 로고
    • Cognitive sequelae in acute respiratory distress syndrome patients with and without recall of the intensive care unit
    • DOI 10.1017/S1355617707070749
    • Larson MJ, Weaver LK, Hopkins RO. Cognitive sequelae in acute respiratory distress syndrome patients with and without recall of the intensive care unit. J Int Neuropsychol Soc 2007;13:595-605 (Pubitemid 350017932)
    • (2007) Journal of the International Neuropsychological Society , vol.13 , Issue.4 , pp. 595-605
    • Larson, M.J.1    Weaver, L.K.2    Hopkins, R.O.3
  • 65
    • 76749158943 scopus 로고    scopus 로고
    • Liberation and animation: Strategies to minimize brain dysfunction in critically ill patients
    • King MS, Render ML, Ely EW, Watson PL. Liberation and animation: strategies to minimize brain dysfunction in critically ill patients. Semin Respir Crit Care Med 2010;31:87-96
    • (2010) Semin Respir Crit Care Med , vol.31 , pp. 87-96
    • King, M.S.1    Render, M.L.2    Ely, E.W.3    Watson, P.L.4
  • 68
    • 20444363574 scopus 로고    scopus 로고
    • Decreased duration of mechanical ventilation when comparing analgesia-based sedation using remifentanil with standard hypnotic-based sedation for up to 10 days in intensive care unit patients: A randomised trial [ISRCTN47583497]
    • Breen D, Karabinis A, Malbrain M, Morais R, Albrecht S, Jarnvig IL, Parkinson P, Kirkham AJ. Decreased duration of mechanical ventilation when comparing analgesia-based sedation using remifentanil with standard hypnotic-based sedation for up to 10 days in intensive care unit patients: a randomised trial [ISRCTN47583497]. Crit Care 2005;9:R200-10
    • (2005) Crit Care , vol.9
    • Breen, D.1    Karabinis, A.2    Malbrain, M.3    Morais, R.4    Albrecht, S.5    Jarnvig, I.L.6    Parkinson, P.7    Kirkham, A.J.8
  • 69
    • 4344582082 scopus 로고    scopus 로고
    • Remifentanil versus morphine analgesia and sedation for mechanically ventilated critically ill patients: A randomized double blind study
    • DOI 10.1097/00000542-200409000-00012
    • Dahaba AA, Grabner T, Rehak PH, List WF, Metzler H. Remifentanil versus morphine analgesia and sedation for mechanically ventilated critically ill patients: a randomized double blind study. Anesthesiology 2004;101:640-6 (Pubitemid 39121643)
    • (2004) Anesthesiology , vol.101 , Issue.3 , pp. 640-646
    • Dahaba, A.A.1    Grabner, T.2    Rehak, P.H.3    List, W.F.4    Metzler, H.5
  • 71
    • 77953076612 scopus 로고    scopus 로고
    • Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: An a priori- designed analysis of the MENDS randomized controlled trial
    • Pandharipande PP, Sanders RD, Girard TD, McGrane S, Thompson JL, Shintani AK, Herr DL, Maze M, Ely EW, MENDS Investigators. Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori- designed analysis of the MENDS randomized controlled trial. Crit Care 2010;14:R38
    • (2010) Crit Care , vol.14
    • Pandharipande, P.P.1    Sanders, R.D.2    Girard, T.D.3    McGrane, S.4    Thompson, J.L.5    Shintani, A.K.6    Herr, D.L.7    Maze, M.8    Ely, E.W.9
  • 73
    • 70350435266 scopus 로고    scopus 로고
    • Prevalence of delirium with dexmedetomidine compared with morphine based therapy after cardiac surgery: A randomized controlled trial (DEXmedetomidine COmpared to Morphine-DEXCOM Study)
    • Shehabi Y, Grant P, Wolfenden H, Hammond N, Bass F, Campbell M, Chen J. Prevalence of delirium with dexmedetomidine compared with morphine based therapy after cardiac surgery: a randomized controlled trial (DEXmedetomidine COmpared to Morphine-DEXCOM Study). Anesthesiology 2009;111:1075-84
    • (2009) Anesthesiology , vol.111 , pp. 1075-1084
    • Shehabi, Y.1    Grant, P.2    Wolfenden, H.3    Hammond, N.4    Bass, F.5    Campbell, M.6    Chen, J.7
  • 75
    • 18944401652 scopus 로고    scopus 로고
    • A multifactorial intervention program reduces the duration of delirium, length of hospitalization, and mortality in delirious patients
    • DOI 10.1111/j.1532-5415.2005.53210.x
    • Lundstrom M, Edlund A, Karlsson S, Brannstrom B, Bucht G, Gustafson Y. A multifactorial intervention program reduces the duration of delirium, length of hospitalization, and mortality in delirious patients. J Am Geriatr Soc 2005;53:622-8 (Pubitemid 41623484)
    • (2005) Journal of the American Geriatrics Society , vol.53 , Issue.4 , pp. 622-628
    • Lundstrom, M.1    Edlund, A.2    Karlsson, S.3    Brannstrom, B.4    Bucht, G.5    Gustafson, Y.6
  • 79
    • 1642415129 scopus 로고    scopus 로고
    • Olanzapine vs haloperidol: Treating delirium in a critical care setting
    • DOI 10.1007/s00134-003-2117-0
    • Skrobik YK, Bergeron N, Dumont M, Gottfried SB. Olanzapine vs haloperidol: treating delirium in a critical care setting. Intensive Care Med 2004;30:444-9 (Pubitemid 38375619)
    • (2004) Intensive Care Medicine , vol.30 , Issue.3 , pp. 444-449
    • Skrobik, Y.K.1    Bergeron, N.2    Dumont, M.3    Gottfried, S.B.4
  • 80
    • 74949114615 scopus 로고    scopus 로고
    • Efficacy and safety of quetiapine in critically ill patients with delirium: A prospective, multicenter, randomized, double-blind, placebo-controlled pilot study
    • Devlin JW, Roberts RJ, Fong JJ, Skrobik Y, Riker RR, Hill NS, Robbins T, Garpestad E. Efficacy and safety of quetiapine in critically ill patients with delirium: a prospective, multicenter, randomized, double-blind, placebo-controlled pilot study. Crit Care Med 2010;38:419-27
    • (2010) Crit Care Med , vol.38 , pp. 419-427
    • Devlin, J.W.1    Roberts, R.J.2    Fong, J.J.3    Skrobik, Y.4    Riker, R.R.5    Hill, N.S.6    Robbins, T.7    Garpestad, E.8
  • 81
    • 35348887919 scopus 로고    scopus 로고
    • Efficacy of risperidone for prevention of postoperative delirium in cardiac surgery
    • Prakanrattana U, Prapaitrakool S. Efficacy of risperidone for prevention of postoperative delirium in cardiac surgery. Anaesth Intensive Care 2007;35:714-9 (Pubitemid 47572095)
    • (2007) Anaesthesia and Intensive Care , vol.35 , Issue.5 , pp. 714-719
    • Prakanrattana, U.1    Prapaitrakool, S.2
  • 83
    • 78649474311 scopus 로고    scopus 로고
    • Effect of rivastigmine as an adjunct to usual care with haloperidol on duration of delirium and mortality in critically ill patients: A multicentre, double-blind, placebo-controlled randomised trial
    • Van Eijk MM, Roes KC, Honing ML, Kuiper MA, Karakus A, van der JM, Spronk PE, van Gool WA, Van Der Mast RC, Kesecioglu J, Slooter AJ. Effect of rivastigmine as an adjunct to usual care with haloperidol on duration of delirium and mortality in critically ill patients: a multicentre, double-blind, placebo-controlled randomised trial. Lancet 2010;376:1829-37
    • (2010) Lancet , vol.376 , pp. 1829-1837
    • Van Eijk, M.M.1    Roes, K.C.2    Honing, M.L.3    Kuiper, M.A.4    Karakus, A.5    Van Der, J.M.6    Spronk, P.E.7    Van Gool, W.A.8    Van Der Mast, R.C.9    Kesecioglu, J.10    Slooter, A.J.11
  • 84
    • 33750113630 scopus 로고    scopus 로고
    • Use of dexmedetomidine to facilitate extubation in surgical intensive-care-unit patients who failed previous weaning attempts following prolonged mechanical ventilation: A pilot study
    • Siobal MS, Kallet RH, Kivett VA, Tang JF. Use of dexmedetomidine to facilitate extubation in surgical intensive-care-unit patients who failed previous weaning attempts following prolonged mechanical ventilation: a pilot study. Respir Care 2006;51:492-6 (Pubitemid 46888380)
    • (2006) Respiratory Care , vol.51 , Issue.5 , pp. 492-496
    • Siobal, M.S.1    Kallet, R.H.2    Kivett, V.A.3    Tang, J.F.4
  • 85
    • 67649450488 scopus 로고    scopus 로고
    • Dexmedetomidine vs. haloperidol in delirious, agitated, intubated patients: A randomised open-label trial
    • Reade MC, O'Sullivan K, Bates S, Goldsmith D, Ainslie WR, Bellomo R. Dexmedetomidine vs. haloperidol in delirious, agitated, intubated patients: a randomised open-label trial. Crit Care 2009;13:R75
    • (2009) Crit Care , vol.13
    • Reade, M.C.1    O'Sullivan, K.2    Bates, S.3    Goldsmith, D.4    Ainslie, W.R.5    Bellomo, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.