Effects of oxidative stress on amyloid precursor protein processing in rat and human platelets

Platelets

Volumn 24, Issue 1, 2013, Pages 26-36

  Ehrlich, Daniela ^a   Hochstrasser, Tanja ^a   Humpel, Christian ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

Alzheimer's disease; APP processing; Hydrogen peroxide; Oxidative stress; Platelets

Indexed keywords

ACTIN; AMYLOID PRECURSOR PROTEIN; GELATINASE A; GLUTATHIONE; HYDROGEN PEROXIDE; PEPTIDE FRAGMENT; SEROTONIN;

ADULT; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOHISTOCHEMISTRY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROCESSING; RAT; THROMBOCYTE; WESTERN BLOTTING;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BLOOD PLATELETS; HUMANS; HYDROGEN PEROXIDE; MATRIX METALLOPROTEINASE 2; OXIDATIVE STRESS; RATS; SEROTONIN;

RATTUS;

EID: 84871799366     PISSN: 09537104     EISSN: 13691635     Source Type: Journal    
DOI: 10.3109/09537104.2012.661104     Document Type: Article

References (55)

1. Bush Al, Martis RN, Rumble B, Moir R, Fuller S, Milward E, Currie J, Ames D, Weidemann A, Fischer P, Multhaup G, Beyreuther K, Masters CL. The amyloid precursor protein of Alzheimer's disease is released by human platelets. J Biol Chem 1990;265:15977-15983.
2. Li QX, Whyte S, Tanner JE, Evin G, Beyreuther K, Masters CL. Secretion of Alzheimer's disease Aß-amyloid peptide by activation of human platelets. Lab Invest 1998;78:461-469.
3. Di Luca M, Colciaghi F, Pastorino L, Borroni B, Padovani A, Cattabeni F. Platelets as a peripheral district where to study pathogenetic mechanisms of alzheimer disease: The case of amyloid precursor protein. Eur J Pharmacol 2000; 405:277-283.
4. Li QX, Fuller SJ, Beyreuther K, Masters CL. The amyloid precursor protein of Alzheimer disease in human brain and blood. J Leukoc Biol. 1999;66:567-574.
5. Evin G, Zhu A, Holsinger RM, Masters CL, Li QX. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets. J Neurosci Res 2003;74:386-392.
6. Canobbio I, Catricalà S, Balduini C, Torti M. Calmodulin regulates the non-amyloidogenic metabolism of amyloid precursor protein in platelets. Biochim Biophys Acta. 2011;13:500-506.
7. Li QX, Berndt MC, Bush AI, Rumble B, Mackenzie I, Friedhuber A, Beyreuther K, Masters CL. Membraneassociated forms of the beta A4 amyloid protein precursor of Alzheimer's disease in human platelet and brain: Surface expression on the activated human platelet. Blood 1994;84:133-142.
8. Tang K, Hynan LS, Baskin F, Rosenberg RN. Platelet amyloid precursor protein processing: A bio-marker for Alzheimer's disease. J Neurol Sci 2006;240:53-58.
9. Skovronsky DM, Lee VM, Praticò D. Amyloid precursor protein and amyloid beta peptide in human platelets. Role of cyclooxygenase and protein kinase C J Biol Chem 2001;20:17036-17043.
10. Li QX, Evin G, Small DH, Multhaup G, Beyreuther K, Masters CL. Proteolytic processing of Alzheimer's disease beta A4 amyloid precursor protein in human platelets. J Biol Chem 1995;270:14140-14147.
11. Chen M, Inestrosa NC, Ross GS, Fernandez HL. Platelets are the principal source of amyloid beta-peptide in human blood. Biochem Biophys Res Commun 1995;213:96-103.
12. Borroni B, Perani D, Broli M, Colciaghi F, Garibotto V, Paghera B, Agosti C, Giubbini R, Di Luca M, Padovani A. Pre-clinical diagnosis of Alzheimer disease combining platelet amyloid precursor protein ratio and rCBF spect analysis. J Neurol 2005;252:1359-1362.
13. Borroni B, Agosti C, Marcello E, Di Luca M, Padovani A. Blood cell markers in Alzheimer disease: Amyloid precursor protein form ratio in platelets. Exp Gerontol 2010;45:53-56.
14. Vignini A, Sartini D, Morganti S, Nanetti L, Luzzi S, Provinciali L, Mazzanti L, Emanuelli M. Platelet amyloid precursor protein isoform expression in Alzheimer's disease: Evidence for peripheral marker. Int J Immunopathol Pharmacol 2011;24: 529-534.
15. Blasko I, Marx F, Grubeck-Loebenstein B, Marksteiner J. Abnormalities of amyloid beta precursor protein expression in platelets of patients with Alzheimer disease: Do we understand them well enough? Arch Neurol 1999;56:889-891.
16. Weidemann A, König G, Bunke D, Fischer P, Salbaum JM, Masters CL, Beyreuther K. Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein. Cell 1989;57:115-126.
17. Pahlsson P, Spitalnik SL. The role of glycosylation in synthesis and secretion of beta-amyloid precursor protein by Chinese hamster ovary cells. Arch Biochem Biophys 1996; 331:177-186.
18. Padovani A, Pastorino L, Borroni B, Colciaghi F, Rozzini L, Monastero R, Perez J, Pettenati C, Mussi M, Parrinello G, et al. Amyloid precursor protein in platelets: A peripheral marker for the diagnosis of sporadic AD. Neurology 2001;57:2243-2248.
19. Borroni B, Agosti C, Marcello E, Di Luca M, Padovani A. Blood cell markers in Alzheimer Disease: Amyloid Precursor Protein form ratio in platelets. Exp Gerontol. 2010;45:53-56.
20. Butterfield DA, Perluigi M, Sultana R. Oxidative stress in Alzheimer's disease brain: New insights from redox proteomics. Eur J Pharmacol 2006;545:39-50.
21. Perry G, Cash AD, Smith MA. Alzheimer disease and oxidative stress. J Biomed Biotechnol 2002;2:120-123.
22. Shaykhalishahi H, Yazdanparast R, Ha HH, Chang YT. Inhibition of H2O2-induced neuroblastoma cell cytotoxicity by triazine derivative, AA3E2. Eur J Pharmacol. 2009;622:1-6.
23. Chetsawang B, Putthaprasart C, Phansuwan-Pujito P, Govitrapong P. Melatonin protects against hydrogen peroxide-iduced cell death signaling in SH-SY5Y cultured cells: Involvement of nuclear factor kappa B, Bax and Bcl-2. J Pineal Res 2006;41: 116-123.
24. Misonou H, Morishima-Kawashima M, Ihara Y. Oxidative stress induces intracellular accumulation of amyloid betaprotein (Abeta) in human neuroblastoma cells. Biochemistry 2000;39:6951-6959.
25. Zhang L, Zhao B, Yew DT, Kusiak JW, Roth GS. Processing of Alzheimer's amyloid precursor protein during H2O2-induced apoptosis in human neuronal cells. Biochem Biophys Res Commun 1997;235:245-848.
26. Hochstrasser T, Ehrlich D, Marksteiner J, Sperner-Unterweger B, Humpel C. Matrix metalloproteinase-2 and epidermal growth factor are decreased in plateletsof Alzheimer patients. Curr Alz Res 2011;Epub ahead of print.
27. Ullrich C, Pirchl M, Humpel C. Hypercholesterolemia in rats impairs the cholinergic system and leads to memory deficits. Mol Cell Neurosci 2010;45:408-417.
28. Pirchl M, Ullrich C, Humpel C. Differential effects of shortand long-term hyperhomocysteinaemia on cholinergic neurons, spatial memory and microbleedings in vivo in rats. E J Neurosci 2010;32:1516-1527.
29. Shattil SJ, Hoxie JA, Cunningham M, Brass LF. Changes in the platelet membrane glycoprotein IIb-IIIa complex during platelet activation. J Biol Chem 1985;260: 11107-11114.
30. Yu Y, Leng T, Yun D, Liu N, Yao J, Dai Y, Yang P, Chen X. Global analysis of the rat and human platelet proteome-the molecular blueprint for illustrating multi-functional platelets and cross-species function evolution. Proteomics 2010;10:2444-2457.
31. Praticò D, Uryu K, Leight S, Trojanoswki JQ, Lee VM. Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis. J Neurosci 2001;21:4183-4187.
32. Clark RA, Klebanoff SJ. Myeloperoxidase-mediated platelet release reaction. J Clin Invest 1979;63:177-183.
33. Henson PM, Johnston RB. Tissue injury in inflammation. Oxidants, proteinases, and cationic proteins. J Clin Invest 1987;79:669-674.
34. Crapo JD. Morphologic changes in pulmonary oxygen toxicity. Annu Rev Physio 1986;48:721-731.
35. Jacob HS, Ingbar SH, Jandl JH. Oxidative hemolysis and erythrocyte metabolism in hereditary acatalasia. J Clin Invest 1965;44:1187-1199.
36. Stone JR, Yang S. Hydrogen peroxide: A signaling messenger. Antioxid Redox Signal 2006;8:243-270.
37. Levine PH, Weinger RS, Simon J, Scoon KL, Krinsky NI. Leukocyte-platelet interaction. Release of hydrogen peroxide by granulocytes as a modulator of platelet reactions. J Clin Invest 1976;57:955-963.
38. Rodvein R, Lindon JN, Levine PH. Physiology and ultrastructure of the blood platelet following exposure to hydrogen peroxide. Br J Haematol 1976;33:19-26.
39. Canoso RT, Rodvien R, Scoon K, Levine PH. Hydrogen peroxide and platelet function. Blood 1974;43:645-656.
40. Lezoualc'h F, Robert SJ. The serotonin 5-HT4 receptor and the amyloid precursor protein processing. Exp Gerontol 2003;38:159-166.
41. Nitsch RM, Wurtman RJ, Growdon JH. Regulation of proteolytic processing of the amyloid beta-protein precursor by first messengers. A novel potential approach for the treatment of Alzheimer's disease. Arzneimittelforschung 1995;45:435-438.
42. Birkedal-Hansen H, Moore WG, Bodden MK, Windsor LJ, Birkedal-Hansen B, DeCarlo A, Engler JA. Matrix metalloproteinases: A review. Crit Rev Oral Biol Med 1993;4: 197-250.
43. Santos-Mart?́nez MJ, Medina C, Jurasz P, Radomski MW. Role of metalloproteinases in platelet function. Thromb Res 2008;121:535-542.
44. Rosenberg GA. Matrixmetalloproteinases and their multiple roles in neurodegenerative diseases. Lancet Neurol 2009;8: 205-216.
45. Roher AE, Kasunic TC, Woods AS, Cotter RJ, Ball MJ, Fridman R. Proteolysis of A beta peptide from Alzheimer disease brain by gelatinase A. Biochem Biophys Res Commun 1994;205:1755-1761.
46. Liao MC, Van Nostrand WE. Degradation of soluble and fibrillar amyloid-protein by matrix metalloproteinase (MT1-MMP) in-vitro. Biochemistry 2010;49:1127-1136.
47. Mlekusch R, Humpel C. Matrix metalloproteinases-2 and-3 are reduced in cerebrospinal fluid with low beta-amyloid1-42 levels. Neurosci Lett 2009;466:135-138.
48. Gralle M, Botelho MG, Wouters FS. Neuroprotective secreted amyloid precursor protein acts by disrupting amyloid precursor protein dimers. J Biol Chem. 2009;29(284):15016-15025.
49. Hilbich C, Mönning U, Grund C, Masters CL, Beyreuther K. Amyloid-like properties of peptides flanking the epitope of amyloid precursor protein-specific monoclonal antibody 22C11. J Biol Chem 1993;268:26571-26577.
50. Quiroz-Baez R, Rojas E, Arias C. Oxidative stress promotes JNK-dependent amyloiogenic processing of normally expressed human APP by differential modification of alpha-, beta-and gamma-secretase expression. Neurochem Int 2009;55:662-670.
51. Casoli T, Di Stefano G, Balietti M, Solazzi M, Giorgetti B, Fattoretti P. Peripheral inflammatory biomarkers of Alzheimer's disease: The role of platelets. Biogerontology 2010;11:627-633.
52. Sorg O. Oxidative stress: A theoretical model or biological reality? C R Biol 2004;327:649-662.
53. Pompella A, Visvikis A, Paolicchi A, De Tata V, Casini AF. The changing faces of glutathione, a cellular protagonist. Biochem Pharmacol 2003;66:1499-1503.
54. Asensi M, Sastre J, Pallardo FV, Lloret A, Lehner M, Garcia-de-la Asuncion J, Viñ a J. Ratio of reduced to oxidized glutathione as indicator of oxidative stress status and DNA damage. Methods Enzymol 1999;299:267-276.
55. Feeney CJ, Frantseva MV, Carlen PL, Pennefather PS, Shulyakova N, Sniffer C, Mills L. Vulnerability of glial cells to hydrogen peroxide in cultured hippocampal slices. Brain Res 2008;1198:1-15.