Expression of endothelial lipase correlates with the size of neointima in a murine model of vascular remodeling

Journal of Atherosclerosis and Thrombosis

Volumn 19, Issue 12, 2012, Pages 1110-1127

  Sun, Li ^a   Ishida, Tatsuro ^a   Okada, Takeaki ^a   Yasuda, Tomoyuki ^a   Hara, Tetsuya ^a   Toh, Ryuji ^a   Shinohara, Masakazu ^a   Yamashita, Tomoya ^a   Rikitake, Yoshiyuki ^a   Hirata, Ken ichi ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

HDL cholesterol; Inflammation; Oxidative stress; Proliferation; Vascular remodeling

Indexed keywords

ANGIOTENSIN II; CD45 ANTIGEN; CELL ADHESION MOLECULE; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERCELLULAR ADHESION MOLECULE 1; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPID; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; VASCULAR CELL ADHESION MOLECULE 1; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY LIGATION; ARTICLE; CAROTID ARTERY; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; IMMUNOBLOTTING; IMMUNOFLOURESCENCE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; KNOCKOUT MOUSE; MALE; MOUSE; NEOINTIMA; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; REAL TIME POLYMERASE CHAIN REACTION; RIBONUCLEASE PROTECTION ASSAY; TRANSGENIC MOUSE; VASCULAR DISEASE; VASCULAR REMODELING; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING; WOUND HEALING;

ANGIOTENSIN II; ANIMALS; CAROTID ARTERY, COMMON; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INFLAMMATION; LIPASE; LIPOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCYTES, SMOOTH MUSCLE; NEOINTIMA; OXIDATIVE STRESS;

EID: 84871790812     PISSN: 13403478     EISSN: 18803873     Source Type: Journal    
DOI: 10.5551/jat.13110     Document Type: Article

References (36)

1. Hui DY: Intimal hyperplasia in murine models. Curr Drug Targets, 2008; 9: 251-260
2. Kawashima S, Yamashita T, Ozaki M, Ohashi Y, Azumi H, Inoue N, Hirata K, Hayashi Y, Itoh H, Yokoyama M: Endothelial NO synthase overexpression inhibits lesion formation in mouse model of vascular remodeling. Arterioscler Thromb Vasc Biol, 2001; 21: 201-207
3. Abbruzzese TA, Guzman RJ, Martin RL, Yee C, Zarins CK, Dalman RL: Matrix metalloproteinase inhibition limits arterial enlargements in a rodent arteriovenous fistula model. Surgery, 1998; 124: 328-334
4. Kumar A, Lindner V: Remodeling with neointima formation in the mouse carotid artery after cessation of blood flow. Arterioscler Thromb Vasc Biol, 1997; 17: 2238-2244
5. da Cunha V, Martin-McNulty B, Vincelette J, Zhang L, Rutledge JC, Wilson DW, Vergona R, Sullivan ME, Wang YX: Interaction between mild hypercholesterolemia, HDL-cholesterol levels, and angiotensin II in intimal hyperplasia in mice. J Lipid Res, 2006; 47: 476-483
6. Sviridov D, Mukhamedova N, Remaley AT, Chin-Dusting J, Nestel P: Antiatherogenic functionality of high density lipoprotein: how much versus how good. J Atheroscler Thromb, 2008; 15: 52-62
7. Cucina A, Scavo MP, Muzzioli L, Coluccia P, Ceccarini S, Fuso A, Cavallaro A: High density lipoproteins downregulate basic fibroblast growth factor production and release in minimally oxidated-LDL treated smooth muscle cells. Atherosclerosis, 2006; 189: 303-309
8. Navab M, Reddy ST, Van Lenten BJ, Anantharamaiah GM, Fogelman AM: The role of dysfunctional HDL in atherosclerosis. J Lipid Res, 2009; 50: S145-S149
9. Hirata K, Dichek HL, Cioffi JA, Choi SY, Leeper NJ, Quintana L, Kronmal GS, Cooper AD, Quertermous T: Cloning of a unique lipase from endothelial cells extends the lipase gene family. J Biol Chem, 1999; 274: 14170-14175
10. Jaye M, Lynch KJ, Krawiec J, Marchadier D, Maugeais C, Doan K, South V, Amin D, Perrone M, Rader DJ: A novel endothelial-derived lipase that modulates HDL metabolism. Nat Genet, 1999; 21: 424-428
11. Ishida T, Choi S, Kundu RK, Hirata K, Rubin EM, Cooper AD, Quertermous T: Endothelial lipase is a major determinant of HDL level. J Clin Invest, 2003; 111: 347-355
12. Azumi H, Hirata K, Ishida T, Kojima Y, Rikitake Y, Takeuchi S, Inoue N, Kawashima S. Hayashi Y, Itoh H, Quertermous T, Yokoyama M: Immunohistochemical localization of endothelial cell-derived lipase in atherosclerotic human coronary arteries. Cardiovasc Res, 2003; 58: 647-654
13. Hara T, Ishida T, Kojima Y, Tanaka H, Yasuda T, Shinohara M, Toh R, Hirata K: Targeted deletion of endothelial lipase increases HDL particles with anti-inflammatory properties both in vitro and in vivo. J Lipid Res, 2011; 52: 57-67
14. Ishida T, Choi SY, Kundu RK, Spin J, Yamashita T, Hirata K, Kojima Y, Yokoyama M, Cooper AD, Quertermous T: Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-E-deficient mice. J Biol Chem, 2004; 279: 45085-45092
15. Ko KW, Paul A, Ma K, Li L, Chan L: Endothelial lipase modulates HDL but has no effect on atherosclerosis development in apoE-/- and LDLR-/- mice. J Lipid Res, 2005; 46: 2586-2594
16. Sun L, Ishida T, Yasuda T, Kojima Y, Honjo T, Yamamoto Y, Yamamoto H, Ishibashi S, Hirata K, Hayashi Y: RAGE mediates oxidized LDL-induced pro-inflammatory effects and atherosclerosis in non-diabetic LDL receptor-deficient mice. Cardiovasc Res, 2009; 82: 371-381
17. Ishida T, Zheng Z, Dichek HL, Wang H, Moreno I, Yang E, Kundu RK, Talbi S, Hirata K, Leung LL, Quertermous T: Molecular cloning of nonsecreted endothelial cell-derived lipase isoforms. Genomics, 2004; 83: 24-33
18. Zhang LN, Velichko S, Vincelette J, Fitch RM, Vergona R, Sullivan ME, Croze E, Wang YX: Interferon-beta attenuates angiotensin II-accelerated atherosclerosis and vascular remodeling in apolipoprotein E deficient mice. Atherosclerosis, 2008; 197: 204-211
19. Senokuchi T, Matsumura T, Sakai M, Matsuo T, Yano M, Kiritoshi S, Sonoda K, Kukidome D, Nishikawa T, Araki E: Extracellular signal-regulated kinase and p38 mitogenactivated protein kinase mediate macrophage proliferation induced by oxidized low-density lipoprotein. Atherosclerosis, 2004; 176: 233-245
20. Yamada T, Kondo T, Numaguchi Y, Tsuzuki M, Matsubara T, Manabe I, Sata M, Nagai R, Murohara T: Angiotensin II receptor blocker inhibits neointimal hyperplasia through regulation of smooth muscle-like progenitor cells. Arterioscler Thromb Vasc Biol, 2007; 27: 2363-2369
21. Feig JE, Shamir R, Fisher EA: Atheroprotective effects of HDL: beyond reverse cholesterol transport. Curr Drug Targets, 2008; 9: 196-203
22. Badellino KO, Wolfe ML, Reilly MP, Rader DJ: Endothelial lipase concentrations are increased in metabolic syndrome and associated with coronary atherosclerosis. PLoS Med, 2006; 3: e22
23. Badellino KO, Wolfe ML, Reilly MP, Rader DJ: Endothelial lipase is increased in vivo by inflammation in humans. Circulation, 2008; 117: 678-685
24. Paradis ME, Badellino KO, Rader DJ, Deshaies Y, Couture P, Archer WR, Bergeron N, Lamarche B: Endothelial lipase is associated with inflammation in humans. J Lipid Res, 2006; 47: 2808-2813
25. Kojima Y, Ishida T, Sun L, Yasuda T, Toh R, Rikitake Y, Fukuda A, Kume N, Koshiyama H, Taniguchi A, Hirata K: Pitavastatin decreases the expression of endothelial lipase both in vitro and in vivo. Cardiovasc Res, 2010; 87: 385-393
26. Annema W, Tietge UJ: Role of hepatic lipase and endothelial lipase in high-density lipoprotein-mediated reverse cholesterol transport. Curr Atheroscler Rep, 2011; 13: 257-265
27. Yasuda T, Ishida T, Rader DJ: Update on the role of endothelial lipase in HDL metabolism, reverse cholesterol transport, and atherosclerosis. Circ J, 2010; 74: 2263-2270
28. Otera H, Ishida T, Nishiuma T, Kobayashi K, Kotani Y, Yasuda T, Kundu RK, Quertermous T, Hirata K, Nishimura Y: Targeted inactivation of endothelial lipase attenuates lung allergic inflammation through raising plasma HDL level and inhibiting eosinophil infiltration. Am J Physiol Lung Cell Mol Physiol, 2009; 296: L594-L602
29. Strauss JG, Zimmermann R, Hrzenjak A, Zhou Y, Kratky D, Levak-Frank S, Kostner GM, Zechner R, Frank S: Endothelial cell-derived lipase mediates uptake and binding of high-density lipoprotein (HDL) particles and the selective uptake of HDL-associated cholesterol esters independent of its enzymic activity. Biochem J, 2002; 368: 69-79
30. Fuki IV, Blanchard N, Jin W, Marchadier DH, Millar JS, Glick JM, Rader DJ: Endogenously produced endothelial lipase enhances binding and cellular processing of plasma lipoproteins via heparan sulfate proteoglycan-mediated pathway. J Biol Chem, 2003; 278: 34331-34338
31. Tanaka H, Ishida T, Johnston TP, Yasuda T, Ueyama T, Kojima Y, Kundu RK, Quertermous T, Ishikawa Y, Hirata K: Role of endothelial lipase in plasma HDL levels in a murine model of hypertriglyceridemia. J Atheroscler Thromb, 2009; 16: 327-338
32. Kojma Y, Hirata K, Ishida T, Shimokawa Y, Inoue N, Kawashima S, Quertermous T, Yokoyama M: Endothelial lipase modulates monocyte adhesion to the vessel wall. A potential role in inflammation. J Biol Chem, 2004; 279: 54032-54038
33. Ahmed W, Orasanu G, Nehra V, Asatryan L, Rader DJ, Ziouzenkova O, Plutzky J: High-density lipoprotein hydrolysis by endothelial lipase activates PPARalpha: a candidate mechanism for high-density lipoprotein-mediated repression of leukocyte adhesion. Circ Res, 2006; 98: 490-498
34. Qiu G, Hill JS: Endothelial lipase promotes apolipoprotein AI-mediated cholesterol efflux in THP-1 macro-phages. Arterioscler Thromb Vasc Biol, 2009; 29: 84-91
35. Qiu G, Ho AC, Yu W, Hill JS: Suppression of endothelial or lipoprotein lipase in THP-1 macrophages attenuates proinflammatory cytokine secretion. J Lipid Res, 2007; 48: 385-394
36. Riederer M, Lechleitner M, Hrzenjak A, Koefeler H, Desoye G, Heinemann A, Frank S: Endothelial lipase (EL) and EL-generated lysophosphatidylcholines promote IL-8 expression in endothelial cells. Atherosclerosis, 2011; 214: 338-344