Targeted inactivation of endothelial lipase attenuates lung allergic inflammation through raising plasma HDL level and inhibiting eosinophil infiltration

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 296, Issue 4, 2009, Pages

  Otera, Hiroshi ^a   Ishida, Tatsuro ^a   Nishiuma, Teruaki ^a   Kobayashi, Kazuyuki ^a   Kotani, Yoshikazu ^a   Yasuda, Tomoyuki ^a   Kundu, Ramendra K ^b   Quertermous, Thomas ^b   Hirata, Ken Ichi ^a   Nishimura, Yoshihiro ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adhesion molecule; Allergy; Cholesterol; Endothelium; High density lipoprotein

Indexed keywords

CYTOKINE; ENDOTHELIAL LIPASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; OVALBUMIN; PHOSPHOLIPASE; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; LIPG PROTEIN, MOUSE; TRIACYLGLYCEROL LIPASE;

ADENOVIRUS; ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; BREATHING MUSCLE; CELL ASSAY; CELL CULTURE; CELL PROTECTION; CELL SURFACE; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; ENDOTHELIUM CELL; EOSINOPHIL COUNT; FEMALE; HUMAN; HUMAN CELL; IMMUNOMODULATION; IN VITRO STUDY; KNOCKOUT MOUSE; LIGAND BINDING; LOEFFLER PNEUMONIA; LUNG ALVEOLUS CELL TYPE 2; LUNG ALVEOLUS EPITHELIUM; LUNG ENDOTHELIUM; LUNG LAVAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; UPREGULATION; WILD TYPE; ANIMAL; BLOOD; BRONCHUS HYPERREACTIVITY; CELL ADHESION; CELL MOTION; CELL STRAIN COS1; CERCOPITHECUS; CYTOLOGY; ENDOTHELIUM; ENZYMOLOGY; EOSINOPHIL; GENE TARGETING; GENETICS; HYPERSENSITIVITY; IMMUNOLOGY; LUNG; METABOLISM; MOUSE MUTANT; PATHOLOGY; PNEUMONIA;

ANIMALS; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; CELL ADHESION; CELL MOVEMENT; CERCOPITHECUS AETHIOPS; CHOLESTEROL, HDL; COS CELLS; ENDOTHELIUM; EOSINOPHILS; GENE TARGETING; HUMANS; HYPERSENSITIVITY; LIPASE; LUNG; MICE; MICE, KNOCKOUT; OVALBUMIN; PNEUMONIA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 65549156671     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.90530.2008     Document Type: Article

References (51)

1. Ahmed W, Orasanu G, Nehra V, Asatryan L, Rader DJ, Ziouzenkova O, Plutzky J. High-density lipoprotein hydrolysis by endothelial lipase activates PPARalpha: a candidate mechanism for high-density lipoprotein-mediated repression of leukocyte adhesion. Circ Res 98: 490-498, 2006. (Pubitemid 43755307)
2. Barter PJ, Nicholls S, Rye KA, Anantharamaiah GM, Navab M, Fogelman AM. Antiinflammatory properties of HDL. Circ Res 95: 764-772, 2004. (Pubitemid 39390578)
3. Broedl UC, Maugeais C, Marchadier D, Glick JM, Rader DJ. Effects of nonlipolytic ligand function of endothelial lipase on high density lipoprotein metabolism in vivo. J Biol Chem 278: 40688-40693, 2003. (Pubitemid 37280882)
4. Canonica GW. Treating asthma as an inflammatory disease. Chest 130: 21S-28S, 2006.
5. Castelli WP, Garrison RJ, Wilson PW, Abbott RD, Kalousdian S, Kannel WB. Incidence of coronary heart disease and lipoprotein cholesterol levels. The Framingham Study. JAMA 256: 2835-2838, 1986.
6. Chihara J, Yamamoto T, Kayaba H, Kakazu T, Kurachi D, Yamamoto J, Iwasa S, Iida K, Urayama O, Kobayashi Y. Degranulation of eosinophils mediated by intercellular adhesion molecule-1 and its ligands is involved in adhesion molecule expression on endothelial cells-selective induction of VCAM-1. J Allergy Clin Immunol 103: S452-S456, 1999. (Pubitemid 29296020)
7. Cirillo DJ, Agrawal Y, Cassano PA. Lipids and pulmonary function in the Third National Health and Nutrition Examination Survey. Am J Epidemiol 155: 842-848, 2002. (Pubitemid 34456995)
8. Cockerill GW, McDonald MC, Mota-Filipe H, Cuzzocrea S, Miller NE, Thiemermann C. High density lipoproteins reduce organ injury and organ dysfunction in a rat model of hemorrhagic shock. FASEB J 15: 1941-1952, 2001. (Pubitemid 32848798)
9. Cockerill GW, Rye KA, Gamble JR, Vadas MA, Barter PJ. Highdensity lipoproteins inhibit cytokine-induced expression of endothelial cell adhesion molecules. Arterioscler Thromb Vasc Biol 15: 1987-1994, 1995.
10. Dobrina A, Menegazzi R, Carlos TM, Nardon E, Cramer R, Zacchi T, Harlan JM, Patriarca P. Mechanisms of eosinophil adherence to cultured vascular endothelial cells. Eosinophils bind to the cytokine-induced ligand vascular cell adhesion molecule-1 via the very late activation antigen-4 integrin receptor. J Clin Invest 88: 20-26, 1991.
11. Doucet C, Brouty-Boye D, Pottin-Clemenceau C, Jasmin C, Canonica GW, Azzarone B. IL-4 and IL-13 specifically increase adhesion molecule and inflammatory cytokine expression in human lung fibroblasts. Int Immunol 10: 1421-1433, 1998. (Pubitemid 28451436)
12. Fuki IV, Blanchard N, Jin W, Marchadier DH, Millar JS, Glick JM, Rader DJ. Endogenously produced endothelial lipase enhances binding and cellular processing of plasma lipoproteins via heparan sulfate proteoglycan- mediated pathway. J Biol Chem 278: 34331-34338, 2003. (Pubitemid 37553277)
13. Gao JX, Issekutz AC. Expression of VCAM-1 and VLA-4 dependent T-lymphocyte adhesion to dermal fibroblasts stimulated with proinflammatory cytokines. Immunology 89: 375-383, 1996.
14. Gilliland FD, Berhane KT, Li YF, Gauderman WJ, McConnell R, Peters J. Children's lung function and antioxidant vitamin, fruit, juice, and vegetable intake. Am J Epidemiol 158: 576-584, 2003. (Pubitemid 37093233)
15. Gordon T, Castelli WP, Hjortland MC, Kannel WB, Dawber TR. High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study. Am J Med 62: 707-714, 1977. (Pubitemid 8110784)
16. Hirata K, Dichek HL, Cioffi JA, Choi SY, Leeper NJ, Quintana L, Kronmal GS, Cooper AD, Quertermous T. Cloning of a unique lipase from endothelial cells extends the lipase gene family. J Biol Chem 274: 14170-14175, 1999. (Pubitemid 129518726)
17. Hirata K, Ishida T, Matsushita H, Tsao PS, Quertermous T. Regulated expression of endothelial cell-derived lipase. Biochem Biophys Res Commun 272: 90-93, 2000. (Pubitemid 30444903)
18. Hu G, Cassano PA. Antioxidant nutrients and pulmonary function: the Third National Health and Nutrition Examination Survey (NHANES III). Am J Epidemiol 151: 975-981, 2000.
19. Ishida T, Choi S, Kundu RK, Hirata K, Rubin EM, Cooper AD, Quertermous T. Endothelial lipase is a major determinant of HDL level. J Clin Invest 111: 347-355, 2003. (Pubitemid 36182211)
20. Ishida T, Choi SY, Kundu RK, Spin J, Yamashita T, Hirata K, Kojima Y, Yokoyama M, Cooper AD, Quertermous T. Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-Edeficient mice. J Biol Chem 279: 45085-45092, 2004. (Pubitemid 39430923)
21. Jaye M, Lynch KJ, Krawiec J, Marchadier D, Maugeais C, Doan K, South V, Amin D, Perrone M, Rader DJ. A novel endothelial-derived lipase that modulates HDL metabolism. Nat Genet 21: 424-428, 1999. (Pubitemid 29159582)
22. Jia GQ, Gonzalo JA, Hidalgo A, Wagner D, Cybulsky M, Gutierrez- Ramos JC. Selective eosinophil transendothelial migration triggered by eotaxin via modulation of Mac-1/ICAM-1 and VLA-4/VCAM-1 interactions. Int Immunol 11: 1-10, 1999. (Pubitemid 29037583)
23. Jin W, Sun GS, Marchadier D, Octtaviani E, Glick JM, Rader DJ. Endothelial cells secrete triglyceride lipase and phospholipase activities in response to cytokines as a result of endothelial lipase. Circ Res 92: 644-650, 2003. (Pubitemid 36417699)
24. Kitayama J, Fuhlbrigge RC, Puri KD, Springer TA. P-selectin, L-selectin, and alpha 4 integrin have distinct roles in eosinophil tethering and arrest on vascular endothelial cells under physiological flow conditions. J Immunol 159: 3929-3939, 1997.
25. Kojma Y, Hirata K, Ishida T, Shimokawa Y, Inoue N, Kawashima S, Quertermous T, Yokoyama M. Endothelial lipase modulates monocyte adhesion to the vessel wall. A potential role in inflammation. J Biol Chem 279: 54032-54038, 2004. (Pubitemid 40053136)
26. Kolleck I, Schlame M, Fechner H, Looman AC, Wissel H, Rustow B. HDL is the major source of vitamin E for type II pneumocytes. Free Radic Biol Med 27: 882-890, 1999. (Pubitemid 29454592)
27. Kudlacz E, Whitney C, Andresen C, Duplantier A, Beckius G, Chupak L, Klein A, Kraus K, Milici A. Pulmonary eosinophilia in a murine model of allergic inflammation is attenuated by small molecule alpha4beta1 antagonists. J Pharmacol Exp Ther 301: 747-752, 2002. (Pubitemid 34429992)
28. Levine DM, Parker TS, Donnelly TM, Walsh A, Rubin AL. In vivo protection against endotoxin by plasma high density lipoprotein. Proc Natl Acad Sci USA 90: 12040-12044, 1993.
29. Martin TR. Recognition of bacterial endotoxin in the lungs. Am J Respir Cell Mol Biol 23: 128-132, 2000.
30. Matsuoka T, Hirata M, Tanaka H, Takahashi Y, Murata T, Kabashima K, Sugimoto Y, Kobayashi T, Ushikubi F, Aze Y, Eguchi N, Urade Y, Yoshida N, Kimura K, Mizoguchi A, Honda Y, Nagai H, Narumiya S. Prostaglandin D2 as a mediator of allergic asthma. Science 287: 2013-2017, 2000. (Pubitemid 30158677)
31. McCoy MG, Sun GS, Marchadier D, Maugeais C, Glick JM, Rader DJ. Characterization of the lipolytic activity of endothelial lipase. J Lipid Res 43: 921-929, 2002. (Pubitemid 34602614)
32. O'Connell BJ, Genest J Jr. High-density lipoproteins and endothelial function. Circulation 104: 1978-1983, 2001.
33. Paradis ME, Badellino KO, Rader DJ, Deshaies Y, Couture P, Archer WR, Bergeron N, Lamarche B. Endothelial lipase is associated with inflammation in humans. J Lipid Res 47: 2808-2813, 2006.
34. Park SH, Park JH, Kang JS, Kang YH. Involvement of transcription factors in plasma HDL protection against TNF-alpha-induced vascular cell adhesion molecule-1 expression. Int J Biochem Cell Biol 35: 168-182, 2003.
35. Patel KD. Eosinophil tethering to interleukin-4-activated endothelial cells requires both P-selectin and vascular cell adhesion molecule-1. Blood 92: 3904-3911, 1998.
36. Qiu G, Ho AC, Yu W, Hill JS. Suppression of endothelial or lipoprotein lipase in THP-1 macrophages attenuates proinflammatory cytokine secretion. J Lipid Res 48: 385-394, 2007. (Pubitemid 46220605)
37. Schäfer T, Ring J. Epidemiology of allergic diseases. Allergy 52, Suppl 38: 14-22; discussion 35-36, 1997. (Pubitemid 27261293)
38. Schäfer T, Ruhdorfer S, Weigl L, Wessner D, Heinrich J, Doring A, Wichmann HE, Ring J. Intake of unsaturated fatty acids and HDL cholesterol levels are associated with manifestations of atopy in adults. Clin Exp Allergy 33: 1360-1367, 2003. (Pubitemid 37289931)
39. Strath M, Warren DJ, Sanderson CJ. Detection of eosinophils using an eosinophil peroxidase assay. Its use as an assay for eosinophil differentiation factors. J Immunol Methods 83: 209-215, 1985. (Pubitemid 16225442)
40. Strauss JG, Zimmermann R, Hrzenjak A, Zhou Y, Kratky D, Levak- Frank S, Kostner GM, Zechner R, Frank S. Endothelial cell-derived lipase mediates uptake and binding of high-density lipoprotein (HDL) particles and the selective uptake of HDL-associated cholesterol esters independent of its enzymic activity. Biochem J 368: 69-79, 2002. (Pubitemid 35463410)
41. Sugatani J, Miwa M, Komiyama Y, Ito S. High-density lipoprotein inhibits the synthesis of platelet-activating factor in human vascular endothelial cells. J Lipid Mediat Cell Signal 13: 73-88, 1996. (Pubitemid 26032174)
42. Syed F, Panettieri RA Jr, Tliba O, Huang C, Li K, Bracht M, Amegadzie B, Griswold D, Li L, Amrani Y. The effect of IL-13 and IL-13R130Q, a naturally occurring IL-13 polymorphism, on the gene expression of human airway smooth muscle cells. Respir Res 6: 9, 2005. (Pubitemid 41358059)
43. Thiemermann C, Patel NS, Kvale EO, Cockerill GW, Brown PA, Stewart KN, Cuzzocrea S, Britti D, Mota-Filipe H, Chatterjee PK. High density lipoprotein (HDL) reduces renal ischemia/reperfusion injury. J Am Soc Nephrol 14: 1833-1843, 2003. (Pubitemid 36750478)
44. Tiffany HL, Alkhatib G, Combadiere C, Berger EA, Murphy PM. CC chemokine receptors 1 and 3 are differentially regulated by IL-5 during maturation of eosinophilic HL-60 cells. J Immunol 160: 1385-1392, 1998. (Pubitemid 28093439)
45. Tomkinson A, Cieslewicz G, Duez C, Larson KA, Lee JJ, Gelfand EW. Temporal association between airway hyperresponsiveness and airway eosinophilia in ovalbumin-sensitized mice. Am J Respir Crit Care Med 163: 721-730, 2001. (Pubitemid 32230836)
46. Troisi RJ, Willett WC, Weiss ST, Trichopoulos D, Rosner B, Speizer FE. A prospective study of diet and adult-onset asthma. Am J Respir Crit Care Med 151: 1401-1408, 1995.
47. Ulevitch RJ, Johnston AR, Weinstein DB. New function for high density lipoproteins. Isolation and characterization of a bacterial lipopolysaccharide- high density lipoprotein complex formed in rabbit plasma. J Clin Invest 67: 827-837, 1981.
48. Voyno-Yasenetskaya TA, Dobbs LG, Erickson SK, Hamilton RL. Low density lipoprotein- and high density lipoprotein-mediated signal transduction and exocytosis in alveolar type II cells. Proc Natl Acad Sci USA 90: 4256-4260, 1993.
49. Wang X, Jin W, Rader DJ. Upregulation of macrophage endothelial lipase by toll-like receptors 4 and 3 modulates macrophage interleukin-10 and -12 production. Circ Res 100: 1008-1015, 2007. (Pubitemid 46598925)
50. Zhang Y, Zanotti I, Reilly MP, Glick JM, Rothblat GH, Rader DJ. Overexpression of apolipoprotein A-I promotes reverse transport of cholesterol from macrophages to feces in vivo. Circulation 108: 661-663, 2003. (Pubitemid 36999247)
51. Zuberi RI, Hsu DK, Kalayci O, Chen HY, Sheldon HK, Yu L, Apgar JR, Kawakami T, Lilly CM, Liu FT. Critical role for galectin-3 in airway inflammation and bronchial hyperresponsiveness in a murine model of asthma. Am J Pathol 165: 2045-2053, 2004. (Pubitemid 39578382)