-
1
-
-
0037141021
-
Cathepsin L regulates CD4+ T cell selection independently of its effect on invariant chain: a role in the generation of positively selecting peptide ligands
-
Honey K, Nakagawa T, Peters C, Rudensky A, (2002) Cathepsin L regulates CD4+ T cell selection independently of its effect on invariant chain: a role in the generation of positively selecting peptide ligands. J Exp Med 195: 1349-1358.
-
(2002)
J Exp Med
, vol.195
, pp. 1349-1358
-
-
Honey, K.1
Nakagawa, T.2
Peters, C.3
Rudensky, A.4
-
2
-
-
74549144385
-
Thymoproteasome shapes immunocompetent repertoire of CD8+ T cells
-
Nitta T, Murata S, Sasaki K, Fujii H, Ripen AM, et al. (2010) Thymoproteasome shapes immunocompetent repertoire of CD8+ T cells. Immunity 32: 29-40.
-
(2010)
Immunity
, vol.32
, pp. 29-40
-
-
Nitta, T.1
Murata, S.2
Sasaki, K.3
Fujii, H.4
Ripen, A.M.5
-
3
-
-
65449189283
-
Thymus-specific serine protease regulates positive selection of a subset of CD4+ thymocytes
-
Gommeaux J, Gregoire C, Nguessan P, Richelme M, Malissen M, et al. (2009) Thymus-specific serine protease regulates positive selection of a subset of CD4+ thymocytes. Eur J Immunol 39: 956-964.
-
(2009)
Eur J Immunol
, vol.39
, pp. 956-964
-
-
Gommeaux, J.1
Gregoire, C.2
Nguessan, P.3
Richelme, M.4
Malissen, M.5
-
4
-
-
52149099867
-
Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance
-
Nedjic J, Aichinger M, Emmerich J, Mizushima N, Klein L, (2008) Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance. Nature 455: 396-400.
-
(2008)
Nature
, vol.455
, pp. 396-400
-
-
Nedjic, J.1
Aichinger, M.2
Emmerich, J.3
Mizushima, N.4
Klein, L.5
-
5
-
-
84862490479
-
Autophagy in the thymic epithelium is dispensable for the development of self-tolerance in a novel mouse model
-
Sukseree S, Mildner M, Rossiter H, Pammer J, Zhang CF, et al. (2012) Autophagy in the thymic epithelium is dispensable for the development of self-tolerance in a novel mouse model. PLoS One 7: e38933.
-
(2012)
PLoS One
, vol.7
-
-
Sukseree, S.1
Mildner, M.2
Rossiter, H.3
Pammer, J.4
Zhang, C.F.5
-
6
-
-
0029009977
-
The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
-
Jiang W, Swiggard WJ, Heufler C, Peng M, Mirza A, et al. (1995) The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing. Nature 375: 151-155.
-
(1995)
Nature
, vol.375
, pp. 151-155
-
-
Jiang, W.1
Swiggard, W.J.2
Heufler, C.3
Peng, M.4
Mirza, A.5
-
7
-
-
0037122011
-
Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance
-
Bonifaz L, Bonnyay D, Mahnke K, Rivera M, Nussenzweig MC, et al. (2002) Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance. J Exp Med 196: 1627-1638.
-
(2002)
J Exp Med
, vol.196
, pp. 1627-1638
-
-
Bonifaz, L.1
Bonnyay, D.2
Mahnke, K.3
Rivera, M.4
Nussenzweig, M.C.5
-
8
-
-
0035903326
-
Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo
-
Hawiger D, Inaba K, Dorsett Y, Guo M, Mahnke K, et al. (2001) Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J Exp Med 194: 769-779.
-
(2001)
J Exp Med
, vol.194
, pp. 769-779
-
-
Hawiger, D.1
Inaba, K.2
Dorsett, Y.3
Guo, M.4
Mahnke, K.5
-
9
-
-
60949109504
-
CD205 (DEC-205): a recognition receptor for apoptotic and necrotic self
-
Shrimpton RE, Butler M, Morel AS, Eren E, Hue SS, et al. (2009) CD205 (DEC-205): a recognition receptor for apoptotic and necrotic self. Mol Immunol 46: 1229-1239.
-
(2009)
Mol Immunol
, vol.46
, pp. 1229-1239
-
-
Shrimpton, R.E.1
Butler, M.2
Morel, A.S.3
Eren, E.4
Hue, S.S.5
-
10
-
-
0037328583
-
In vitro evidence for participation of DEC-205 expressed by thymic cortical epithelial cells in clearance of apoptotic thymocytes
-
Small M, Kraal G, (2003) In vitro evidence for participation of DEC-205 expressed by thymic cortical epithelial cells in clearance of apoptotic thymocytes. Int Immunol 15: 197-203.
-
(2003)
Int Immunol
, vol.15
, pp. 197-203
-
-
Small, M.1
Kraal, G.2
-
11
-
-
0033818104
-
A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells
-
Guo M, Gong S, Maric S, Misulovin Z, Pack M, et al. (2000) A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells. Hum Immunol 61: 729-738.
-
(2000)
Hum Immunol
, vol.61
, pp. 729-738
-
-
Guo, M.1
Gong, S.2
Maric, S.3
Misulovin, Z.4
Pack, M.5
-
12
-
-
0028178784
-
T cell receptor antagonist peptides induce positive selection
-
Hogquist KA, Jameson SC, Heath WR, Howard JL, Bevan MJ, et al. (1994) T cell receptor antagonist peptides induce positive selection. Cell 76: 17-27.
-
(1994)
Cell
, vol.76
, pp. 17-27
-
-
Hogquist, K.A.1
Jameson, S.C.2
Heath, W.R.3
Howard, J.L.4
Bevan, M.J.5
-
13
-
-
0031897801
-
Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements
-
Barnden MJ, Allison J, Heath WR, Carbone FR, (1998) Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements. Immunol Cell Biol 76: 34-40.
-
(1998)
Immunol Cell Biol
, vol.76
, pp. 34-40
-
-
Barnden, M.J.1
Allison, J.2
Heath, W.R.3
Carbone, F.R.4
-
14
-
-
0036196669
-
Tracking salmonella-specific CD4 T cells in vivo reveals a local mucosal response to a disseminated infection
-
McSorley SJ, Asch S, Costalonga M, Reinhardt RL, Jenkins MK, (2002) Tracking salmonella-specific CD4 T cells in vivo reveals a local mucosal response to a disseminated infection. Immunity 16: 365-377.
-
(2002)
Immunity
, vol.16
, pp. 365-377
-
-
McSorley, S.J.1
Asch, S.2
Costalonga, M.3
Reinhardt, R.L.4
Jenkins, M.K.5
-
15
-
-
0021256517
-
Monoclonal antibodies to stromal cell types of the mouse thymus
-
Van Vliet E, Melis M, Van Ewijk W, (1984) Monoclonal antibodies to stromal cell types of the mouse thymus. Eur J Immunol 14: 524-529.
-
(1984)
Eur J Immunol
, vol.14
, pp. 524-529
-
-
van Vliet, E.1
Melis, M.2
van Ewijk, W.3
-
16
-
-
84861142913
-
Mesenchymal cells regulate retinoic acid receptor-dependent cortical thymic epithelial cell homeostasis
-
Sitnik KM, Kotarsky K, White AJ, Jenkinson WE, Anderson G, et al. (2012) Mesenchymal cells regulate retinoic acid receptor-dependent cortical thymic epithelial cell homeostasis. J Immunol 188: 4801-4809.
-
(2012)
J Immunol
, vol.188
, pp. 4801-4809
-
-
Sitnik, K.M.1
Kotarsky, K.2
White, A.J.3
Jenkinson, W.E.4
Anderson, G.5
-
17
-
-
78049496246
-
Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells
-
White AJ, Nakamura K, Jenkinson WE, Saini M, Sinclair C, et al. (2010) Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells. J Immunol 185: 4769-4776.
-
(2010)
J Immunol
, vol.185
, pp. 4769-4776
-
-
White, A.J.1
Nakamura, K.2
Jenkinson, W.E.3
Saini, M.4
Sinclair, C.5
-
18
-
-
59849123625
-
Checkpoints in the development of thymic cortical epithelial cells
-
Shakib S, Desanti GE, Jenkinson WE, Parnell SM, Jenkinson EJ, et al. (2009) Checkpoints in the development of thymic cortical epithelial cells. J Immunol 182: 130-137.
-
(2009)
J Immunol
, vol.182
, pp. 130-137
-
-
Shakib, S.1
Desanti, G.E.2
Jenkinson, W.E.3
Parnell, S.M.4
Jenkinson, E.J.5
-
19
-
-
79951715831
-
Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development
-
Lei Y, Ripen AM, Ishimaru N, Ohigashi I, Nagasawa T, et al. (2011) Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development. J Exp Med 208: 383-394.
-
(2011)
J Exp Med
, vol.208
, pp. 383-394
-
-
Lei, Y.1
Ripen, A.M.2
Ishimaru, N.3
Ohigashi, I.4
Nagasawa, T.5
-
21
-
-
71749103257
-
Spatial mapping of thymic stromal microenvironments reveals unique features influencing T lymphoid differentiation
-
Griffith AV, Fallahi M, Nakase H, Gosink M, Young B, et al. (2009) Spatial mapping of thymic stromal microenvironments reveals unique features influencing T lymphoid differentiation. Immunity 31: 999-1009.
-
(2009)
Immunity
, vol.31
, pp. 999-1009
-
-
Griffith, A.V.1
Fallahi, M.2
Nakase, H.3
Gosink, M.4
Young, B.5
-
22
-
-
58149316251
-
Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance
-
Yano M, Kuroda N, Han H, Meguro-Horike M, Nishikawa Y, et al. (2008) Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance. J Exp Med 205: 2827-2838.
-
(2008)
J Exp Med
, vol.205
, pp. 2827-2838
-
-
Yano, M.1
Kuroda, N.2
Han, H.3
Meguro-Horike, M.4
Nishikawa, Y.5
-
23
-
-
75149138278
-
Control of central self-tolerance induction by autoreactive CD4+ thymocytes
-
Irla M, Hollander G, Reith W, (2010) Control of central self-tolerance induction by autoreactive CD4+ thymocytes. Trends Immunol 31: 71-79.
-
(2010)
Trends Immunol
, vol.31
, pp. 71-79
-
-
Irla, M.1
Hollander, G.2
Reith, W.3
-
24
-
-
58849129765
-
Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells
-
Fiorini E, Ferrero I, Merck E, Favre S, Pierres M, et al. (2008) Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells. J Immunol 181: 8199-8203.
-
(2008)
J Immunol
, vol.181
, pp. 8199-8203
-
-
Fiorini, E.1
Ferrero, I.2
Merck, E.3
Favre, S.4
Pierres, M.5
-
25
-
-
45949085887
-
Neural crest origin of perivascular mesenchyme in the adult thymus
-
Muller SM, Stolt CC, Terszowski G, Blum C, Amagai T, et al. (2008) Neural crest origin of perivascular mesenchyme in the adult thymus. J Immunol 180: 5344-5351.
-
(2008)
J Immunol
, vol.180
, pp. 5344-5351
-
-
Muller, S.M.1
Stolt, C.C.2
Terszowski, G.3
Blum, C.4
Amagai, T.5
-
26
-
-
35748941369
-
Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire
-
Gray D, Abramson J, Benoist C, Mathis D, (2007) Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire. J Exp Med 204: 2521-2528.
-
(2007)
J Exp Med
, vol.204
, pp. 2521-2528
-
-
Gray, D.1
Abramson, J.2
Benoist, C.3
Mathis, D.4
-
27
-
-
79953083485
-
Cytokine crosstalk for thymic medulla formation
-
Nitta T, Ohigashi I, Nakagawa Y, Takahama Y, (2011) Cytokine crosstalk for thymic medulla formation. Curr Opin Immunol 23: 190-197.
-
(2011)
Curr Opin Immunol
, vol.23
, pp. 190-197
-
-
Nitta, T.1
Ohigashi, I.2
Nakagawa, Y.3
Takahama, Y.4
-
28
-
-
0027427713
-
CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection
-
Yamashita I, Nagata T, Tada T, Nakayama T, (1993) CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection. Int Immunol 5: 1139-1150.
-
(1993)
Int Immunol
, vol.5
, pp. 1139-1150
-
-
Yamashita, I.1
Nagata, T.2
Tada, T.3
Nakayama, T.4
-
29
-
-
0033120586
-
CD69 expression discriminates MHC-dependent and -independent stages of thymocyte positive selection
-
Hare KJ, Jenkinson EJ, Anderson G, (1999) CD69 expression discriminates MHC-dependent and-independent stages of thymocyte positive selection. J Immunol 162: 3978-3983.
-
(1999)
J Immunol
, vol.162
, pp. 3978-3983
-
-
Hare, K.J.1
Jenkinson, E.J.2
Anderson, G.3
-
30
-
-
84862814979
-
Selection of regulatory T cells in the thymus
-
Hsieh CS, Lee HM, Lio CW, (2012) Selection of regulatory T cells in the thymus. Nat Rev Immunol 12: 157-167.
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 157-167
-
-
Hsieh, C.S.1
Lee, H.M.2
Lio, C.W.3
-
31
-
-
63449108301
-
Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity
-
Ohnmacht C, Pullner A, King SB, Drexler I, Meier S, et al. (2009) Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. J Exp Med 206: 549-559.
-
(2009)
J Exp Med
, vol.206
, pp. 549-559
-
-
Ohnmacht, C.1
Pullner, A.2
King, S.B.3
Drexler, I.4
Meier, S.5
-
32
-
-
0032494112
-
Highly restricted T cell repertoire shaped by a single major histocompatibility complex-peptide ligand in the presence of a single rearranged T cell receptor beta chain
-
Fukui Y, Hashimoto O, Inayoshi A, Gyotoku T, Sano T, et al. (1998) Highly restricted T cell repertoire shaped by a single major histocompatibility complex-peptide ligand in the presence of a single rearranged T cell receptor beta chain. J Exp Med 188: 897-907.
-
(1998)
J Exp Med
, vol.188
, pp. 897-907
-
-
Fukui, Y.1
Hashimoto, O.2
Inayoshi, A.3
Gyotoku, T.4
Sano, T.5
-
33
-
-
0034541172
-
Altered selection of CD4+ T cells by class II MHC bound with dominant and low abundance self-peptides
-
Gaszewska-Mastalarz A, Muranski P, Chmielowski B, Kraj P, Ignatowicz L, (2000) Altered selection of CD4+ T cells by class II MHC bound with dominant and low abundance self-peptides. J Immunol 165: 6099-6106.
-
(2000)
J Immunol
, vol.165
, pp. 6099-6106
-
-
Gaszewska-Mastalarz, A.1
Muranski, P.2
Chmielowski, B.3
Kraj, P.4
Ignatowicz, L.5
-
34
-
-
0030058657
-
The repertoire of T cells shaped by a single MHC/peptide ligand
-
Ignatowicz L, Kappler J, Marrack P, (1996) The repertoire of T cells shaped by a single MHC/peptide ligand. Cell 84: 521-529.
-
(1996)
Cell
, vol.84
, pp. 521-529
-
-
Ignatowicz, L.1
Kappler, J.2
Marrack, P.3
-
35
-
-
0038792101
-
Induction of CD4+/CD25+ regulatory T cells by targeting of antigens to immature dendritic cells
-
Mahnke K, Qian Y, Knop J, Enk AH, (2003) Induction of CD4+/CD25+ regulatory T cells by targeting of antigens to immature dendritic cells. Blood 101: 4862-4869.
-
(2003)
Blood
, vol.101
, pp. 4862-4869
-
-
Mahnke, K.1
Qian, Y.2
Knop, J.3
Enk, A.H.4
-
36
-
-
12144286596
-
In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination
-
Bonifaz LC, Bonnyay DP, Charalambous A, Darguste DI, Fujii S, et al. (2004) In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination. J Exp Med 199: 815-824.
-
(2004)
J Exp Med
, vol.199
, pp. 815-824
-
-
Bonifaz, L.C.1
Bonnyay, D.P.2
Charalambous, A.3
Darguste, D.I.4
Fujii, S.5
-
37
-
-
0036645294
-
Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase
-
Cohen PL, Caricchio R, Abraham V, Camenisch TD, Jennette JC, et al. (2002) Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase. J Exp Med 196: 135-140.
-
(2002)
J Exp Med
, vol.196
, pp. 135-140
-
-
Cohen, P.L.1
Caricchio, R.2
Abraham, V.3
Camenisch, T.D.4
Jennette, J.C.5
-
38
-
-
0034735552
-
The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments
-
Mahnke K, Guo M, Lee S, Sepulveda H, Swain SL, et al. (2000) The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments. J Cell Biol 151: 673-684.
-
(2000)
J Cell Biol
, vol.151
, pp. 673-684
-
-
Mahnke, K.1
Guo, M.2
Lee, S.3
Sepulveda, H.4
Swain, S.L.5
|