Tracking Salmonella-specific CD4 T cells in vivo reveals a local mucosal response to a disseminated infection

Immunity

Volumn 16, Issue 3, 2002, Pages 365-377

  McSorley, Stephen J ^a,b   Asch, Sarah ^a   Costalonga, Massimo ^a   Reinhardt, R Lee ^a   Jenkins, Marc K ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; INTERLEUKIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BACTERIUM; CELL ACTIVATION; CELL ASSAY; CELL MIGRATION; CELL PROLIFERATION; CELL SPECIFICITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; IMMUNE RESPONSE; IN VIVO STUDY; INTESTINE; LIVER; LYMPHOID TISSUE; MOUSE; MUCOSA; NONHUMAN; PATHOGENICITY; PEYER PATCH; PRIORITY JOURNAL; SALMONELLA; SALMONELLOSIS; SPLEEN; T LYMPHOCYTE; TIME;

EID: 0036196669     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(02)00289-3     Document Type: Article

References (42)

1. The route of enteric infection in normal mice
2. Revealing the in vivo behavior of CD4+ T cells specific for an antigen expressed in Escherichia coli
3. r) BALB/c mice
4. The relationship of MHC-peptide binding and T cell activation probed using chemically defined MHC class II oligomers
5. Identification of a natural T cell epitope presented by Salmonella-infected macrophages and recognised by T cells from orally immunised mice
6. T cell memory
7. Flagellin, a novel mediator of Salmonella-induced epithelial activation and systemic inflammation: IκBα degradation, induction of nitric oxide synthase, induction of proinflammatory mediators, and cardiovascular dysfunction
8. Generation of gamma interferon responses in murine Peyer's patches following oral immunization
9. Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory response
10. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
11. Salmonella typhimurium aroA- infection in gene-targeted immunodeficient mice: Major role of CD4+ TCR-α β cells and IFN-γ in bacterial clearance independent of intracellular location
12. Intestinal and splenic T cell responses to enteric Listeria monocytogenes infection: Distinct repertoires of responding CD8 T lymphocytes
13. In vivo detection of dendritic cell antigen presentation to CD4+ T cells
14. Mucosal immunity and inflammation. I. Mucosal dendritic cells: Their specialized role in initiating T cell responses
15. Localization of distinct Peyer's patch dendritic cell subsets and their recruitment by chemokines macrophage inflammatory protein (MIP)-3α, MIP-3β, and secondary lymphoid organ chemokine
16. In vivo activation of antigen-specific CD4 T cells
17. Salmonellosis: Host immune responses and bacterial virulence determinants
18. Entry of microbes into the host: Using M cells to break the mucosal barrier
19. Memory CD8+ T cell differentiation: Initial antigen encounter triggers a developmental program in naive cells
20. Amino acids responsible for flagellar shape are distributed in terminal regions of flagellin
21. Visualisation of peptide-specific T cell immunity and peripheral tolerance induction in vivo
22. A natural immunological adjuvant enhances T cell clonal expansion through a CD28-dependent, interleukin (IL)-2-independent mechanism
23. Cassette vectors directing expression of T cell receptor genes in transgenic mice
24. Phenotype, and migration properties of three major subsets of tissue homing T cells in sheep
25. Class II MHC antigen (Ia)-bearing dendritic cells in the epithelium of the rat intestine
26. Igh-6(-/-) (B-cell-deficient) mice fail to mount solid acquired resistance to oral challenge with virulent Salmonella enterica serovar typhimurium and show impaired Th1 T-cell responses to Salmonella antigens
27. Tracking antigen-specific helper T cell responses
28. Antibody is required for protection against virulent but not attenuated Salmonella enterica serovar typhimurium
29. Vaccine efficacy of Salmonella strains expressing glycoprotein 63 with different promoters
30. Characterization of CD4+ T cell responses during natural infection with Salmonella typhimurium
31. Early programming of T cell populations responding to bacterial infection
32. Cutting edge: Role of B lymphocytes in protective immunity against Salmonella typhimurium infection
33. Use of adoptive transfer of T-cell-antigen-receptor-transgenic T cells for the study of T-cell activation in vivo
34. Fluorescent dyes for lymphocyte migration and proliferation studies
35. Organ-specific regulation of the CD8 T cell response to Listeria monocytogenes infection
36. Visualizing the generation of memory CD4 T cells in the whole body
37. Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria
38. Confrontation between intracellular bacteria and the immune system
39. The effect of non-lethal deflagellation on bacterial motility and observations on flagellar regeneration
40. Regulation of host immune responses by modification of Salmonella virulence genes
41. Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes
42. Expression of intestine-specific antigen reveals novel pathways of CD8 T cell tolerance induction