Altered selection of CD4+ T cells by class II MHC bound with dominant and low abundance self-peptides

Journal of Immunology

Volumn 165, Issue 11, 2000, Pages 6099-6106

  Gaszewska Mastalarz, A ^a   Muranski, P ^a   Chmielowski, B ^a   Kraj, P ^a   Ignatowicz, L ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; MAJOR HISTOCOMPATIBILITY COMPLEX; MEMORY CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE; THYMUS; TRANSGENIC MOUSE;

EID: 0034541172     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.11.6099     Document Type: Article

References (25)

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17. + T cells, a single class II MHC/peptide complex positively selects TCRs with various antigen specificities
18. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
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23. Self-reactive T cells selected on thymic cortical epithelium are polyclonal and are pathogenic in vivo
24. Minimal level of MHC class II expression is sufficient to abrogate autoreactivity
25. Progression of autoimmune diabetes driven by avidity maturation of a T-cell population