Exome Capture Sequencing of Adenoma Reveals Genetic Alterations in Multiple Cellular Pathways at the Early Stage of Colorectal Tumorigenesis

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Zhou, Donger ^a,b   Yang, Liu ^a,b   Zheng, Liangtao ^a,b   Ge, Weiting ^a,b   Li, Dan ^a,b   Zhang, Yong ^c   Hu, Xueda ^c   Gao, Zhibo ^c   Xu, Jinghong ^b   Huang, Yanqin ^a,b   Hu, Hanguang ^a,b   Zhang, Hang ^a,b   Zhang, Hao ^c   Liu, Mingming ^c   Yang, Huanming ^c   Zheng, Lei ^b,d   Zheng, Shu ^a,b  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c BGI SHENZHEN   (China)

^d JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOACYL TRANSFER RNA; BIOLOGICAL MARKER; CALCIUM; CHEMOKINE; CYTOKINE; CYTOKINE RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GLYCOLIPID; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; UBIQUITIN; WNT PROTEIN;

AGED; ARTICLE; BIRC6 GENE; CALCIUM SIGNALING; CARCINOGENESIS; CDH20 GENE; CELL ADHESION; COL4A6 GENE; COLORECTAL ADENOMA; COLORECTAL CARCINOGENESIS; COLORECTAL CARCINOMA; CONTROLLED STUDY; EFR3A GENE; EXOME; EXOME CAPTURE SEQUENCING; FTHL17 GENE; GENE; GENE IDENTIFICATION; GENE MUTATION; GENETIC VARIABILITY; GLCCI1 GENE; GLUCONEOGENESIS; GLYCOLYSIS; HUMAN; HUMAN TISSUE; KRTHB4 GENE; LAMA3 GENE; LIPID METABOLISM; MAJOR CLINICAL STUDY; MALE; MOLECULAR EVOLUTION; MUTATIONAL ANALYSIS; NMBR GENE; NRXN3 GENE; OR6X1 GENE; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; RBFOX1 GENE; RNA SYNTHESIS; SEQUENCE ANALYSIS; SLC15A3 GENE; TUMOR SUPPRESSOR GENE;

ADENOCARCINOMA; ADENOMA; AGED; CELL ADHESION; CELL TRANSFORMATION, NEOPLASTIC; CHROMOSOME MAPPING; COLORECTAL NEOPLASMS; EXOME; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC VARIATION; GENOME, HUMAN; HUMANS; MALE; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA;

EID: 84871726922     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053310     Document Type: Article

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