메뉴 건너뛰기




Volumn 43, Issue 8, 2012, Pages 677-685

Early-onset Alzheimer's Disease: Nonamnestic Subtypes and Type 2 AD

Author keywords

Alzheimer's disease; Amnestic; Apolipoprotein; Dementia; Presenilin

Indexed keywords

APOLIPOPROTEIN E4; PRESENILIN 1; PRESENILIN 2;

EID: 84871645829     PISSN: 01884409     EISSN: 18735487     Source Type: Journal    
DOI: 10.1016/j.arcmed.2012.11.009     Document Type: Review
Times cited : (131)

References (102)
  • 1
    • 0028856460 scopus 로고
    • An English translation of Alzheimer's 1907 paper, Uber eine eigenartige Erkankung der Hirnrinde
    • Alzheimer A., Stelzmann R.A., Schnitzlein H.N., et al. An English translation of Alzheimer's 1907 paper, Uber eine eigenartige Erkankung der Hirnrinde. Clin Anat 1995, 8:429-431.
    • (1995) Clin Anat , vol.8 , pp. 429-431
    • Alzheimer, A.1    Stelzmann, R.A.2    Schnitzlein, H.N.3
  • 2
    • 0014313861 scopus 로고
    • The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects
    • Blessed G., Tomlinson B.E., Roth M. The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Br J Psychiatry 1968, 114:797-811.
    • (1968) Br J Psychiatry , vol.114 , pp. 797-811
    • Blessed, G.1    Tomlinson, B.E.2    Roth, M.3
  • 3
    • 0016942101 scopus 로고
    • Editorial: The prevalence and malignancy of Alzheimer disease. A major killer
    • Katzman R. Editorial: The prevalence and malignancy of Alzheimer disease. A major killer. Arch Neurol 1976, 33:217-218.
    • (1976) Arch Neurol , vol.33 , pp. 217-218
    • Katzman, R.1
  • 4
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G., Drachman D., Folstein M., et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984, 34:939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3
  • 6
    • 33749538565 scopus 로고    scopus 로고
    • [Presenile dementia in memory clinics-incidence rates and clinical features]
    • Bickel H., Burger K., Hampel H., et al. Nervenarzt 2006, 77:1079-1085.
    • (2006) Nervenarzt , vol.77 , pp. 1079-1085
    • Bickel, H.1    Burger, K.2    Hampel, H.3
  • 7
    • 78650372020 scopus 로고    scopus 로고
    • Prevalence and causes of young onset dementia in an English health district
    • Renvoize E., Hanson M., Dale M. Prevalence and causes of young onset dementia in an English health district. Int J Geriatr Psychiatry 2011, 26:106-107.
    • (2011) Int J Geriatr Psychiatry , vol.26 , pp. 106-107
    • Renvoize, E.1    Hanson, M.2    Dale, M.3
  • 9
    • 30844435503 scopus 로고    scopus 로고
    • Early-onset dementia: frequency and causes compared to late-onset dementia
    • McMurtray A., Clark D.G., Christine D., et al. Early-onset dementia: frequency and causes compared to late-onset dementia. Dement Geriatr Cogn Disord 2006, 21:59-64.
    • (2006) Dement Geriatr Cogn Disord , vol.21 , pp. 59-64
    • McMurtray, A.1    Clark, D.G.2    Christine, D.3
  • 10
    • 33745898208 scopus 로고    scopus 로고
    • Family history of dementia in early-onset versus very late-onset Alzheimer's disease
    • McMurtray A.M., Ringman J., Chao S.Z., et al. Family history of dementia in early-onset versus very late-onset Alzheimer's disease. Int J Geriatr Psychiatry 2006, 21:597-598.
    • (2006) Int J Geriatr Psychiatry , vol.21 , pp. 597-598
    • McMurtray, A.M.1    Ringman, J.2    Chao, S.Z.3
  • 11
    • 79951722994 scopus 로고    scopus 로고
    • Early-onset versus late-onset Alzheimer's disease: the case of the missing APOE varepsilon4 allele
    • van der Flier W.M., Pijnenburg Y.A., Fox N.C., et al. Early-onset versus late-onset Alzheimer's disease: the case of the missing APOE varepsilon4 allele. Lancet Neurol 2011, 10:280-288.
    • (2011) Lancet Neurol , vol.10 , pp. 280-288
    • van der Flier, W.M.1    Pijnenburg, Y.A.2    Fox, N.C.3
  • 12
    • 33747059031 scopus 로고    scopus 로고
    • The effect of APOE genotype on clinical phenotype in Alzheimer disease
    • van der Flier W.M., Schoonenboom S.N., Pijnenburg Y.A., et al. The effect of APOE genotype on clinical phenotype in Alzheimer disease. Neurology 2006, 67:526-527.
    • (2006) Neurology , vol.67 , pp. 526-527
    • van der Flier, W.M.1    Schoonenboom, S.N.2    Pijnenburg, Y.A.3
  • 13
    • 32544448231 scopus 로고    scopus 로고
    • Reduced hippocampal volume in non-demented carriers of the apolipoprotein E epsilon4: relation to chronological age and recognition memory
    • Lind J., Larsson A., Persson J., et al. Reduced hippocampal volume in non-demented carriers of the apolipoprotein E epsilon4: relation to chronological age and recognition memory. Neurosci Lett 2006, 396:23-27.
    • (2006) Neurosci Lett , vol.396 , pp. 23-27
    • Lind, J.1    Larsson, A.2    Persson, J.3
  • 14
    • 0347719366 scopus 로고    scopus 로고
    • Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia
    • Reiman E.M., Chen K., Alexander G.E., et al. Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia. Proc Natl Acad Sci USA 2004, 101:284-289.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 284-289
    • Reiman, E.M.1    Chen, K.2    Alexander, G.E.3
  • 15
    • 33845800866 scopus 로고    scopus 로고
    • Apolipoprotein E epsilon4 allele frequency and age at onset of Alzheimer's disease
    • Davidson Y., Gibbons L., Pritchard A., et al. Apolipoprotein E epsilon4 allele frequency and age at onset of Alzheimer's disease. Dement Geriatr Cogn Disord 2007, 23:60-66.
    • (2007) Dement Geriatr Cogn Disord , vol.23 , pp. 60-66
    • Davidson, Y.1    Gibbons, L.2    Pritchard, A.3
  • 16
    • 30344434961 scopus 로고    scopus 로고
    • Apolipoprotein e genotype modifies the phenotype of Alzheimer disease
    • Schott J.M., Ridha B.H., Crutch S.J., et al. Apolipoprotein e genotype modifies the phenotype of Alzheimer disease. Arch Neurol 2006, 63:155-156.
    • (2006) Arch Neurol , vol.63 , pp. 155-156
    • Schott, J.M.1    Ridha, B.H.2    Crutch, S.J.3
  • 17
    • 79958274677 scopus 로고    scopus 로고
    • ApoE E4 is a susceptibility factor in amnestic but not aphasic dementias
    • Rogalski E.J., Rademaker A., Harrison T.M., et al. ApoE E4 is a susceptibility factor in amnestic but not aphasic dementias. Alzheimer Dis Assoc Disord 2011, 25:159-163.
    • (2011) Alzheimer Dis Assoc Disord , vol.25 , pp. 159-163
    • Rogalski, E.J.1    Rademaker, A.2    Harrison, T.M.3
  • 18
    • 79957531921 scopus 로고    scopus 로고
    • Clinical features and APOE genotype of pathologically proven early-onset Alzheimer disease
    • Balasa M., Gelpi E., Antonell A., et al. Clinical features and APOE genotype of pathologically proven early-onset Alzheimer disease. Neurology 2011, 76:1720-1725.
    • (2011) Neurology , vol.76 , pp. 1720-1725
    • Balasa, M.1    Gelpi, E.2    Antonell, A.3
  • 19
    • 32844465332 scopus 로고    scopus 로고
    • Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin-1 gene
    • Larner A.J., Doran M. Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin-1 gene. J Neurol 2006, 253:139-158.
    • (2006) J Neurol , vol.253 , pp. 139-158
    • Larner, A.J.1    Doran, M.2
  • 20
    • 84867328267 scopus 로고    scopus 로고
    • Comparison of clinical characteristics between familial and non-familial early onset Alzheimer's disease
    • Joshi A., Ringman J.M., Lee A.S., et al. Comparison of clinical characteristics between familial and non-familial early onset Alzheimer's disease. J Neurol 2012, 259:2182-2188.
    • (2012) J Neurol , vol.259 , pp. 2182-2188
    • Joshi, A.1    Ringman, J.M.2    Lee, A.S.3
  • 21
    • 79959193198 scopus 로고    scopus 로고
    • Genetic counseling and testing for Alzheimer disease: joint practice guidelines of the American College of Medical Genetics and the National Society of Genetic Counselors
    • Goldman J.S., Hahn S.E., Catania J.W., et al. Genetic counseling and testing for Alzheimer disease: joint practice guidelines of the American College of Medical Genetics and the National Society of Genetic Counselors. Genet Med 2011, 13:597-605.
    • (2011) Genet Med , vol.13 , pp. 597-605
    • Goldman, J.S.1    Hahn, S.E.2    Catania, J.W.3
  • 22
    • 77953861808 scopus 로고    scopus 로고
    • A novel PSEN1 mutation (K239N) associated with Alzheimer's disease with wide range age of onset and slow progression
    • Llado A., Fortea J., Ojea T., et al. A novel PSEN1 mutation (K239N) associated with Alzheimer's disease with wide range age of onset and slow progression. Eur J Neurol 2010, 17:994-996.
    • (2010) Eur J Neurol , vol.17 , pp. 994-996
    • Llado, A.1    Fortea, J.2    Ojea, T.3
  • 23
    • 79961164438 scopus 로고    scopus 로고
    • Alzheimer's genetics in the GWAS era: a continuing story of replications and refutations
    • Bertram L. Alzheimer's genetics in the GWAS era: a continuing story of replications and refutations. Curr Neurol Neurosci Rep 2011, 11:246-253.
    • (2011) Curr Neurol Neurosci Rep , vol.11 , pp. 246-253
    • Bertram, L.1
  • 24
    • 0028915233 scopus 로고
    • Cognitive changes in young-old adults: effect of family history of dementia
    • La Rue A., O'Hara R., Matsuyama S.S., et al. Cognitive changes in young-old adults: effect of family history of dementia. J Clin Exp Neuropsychol 1995, 17:65-70.
    • (1995) J Clin Exp Neuropsychol , vol.17 , pp. 65-70
    • La Rue, A.1    O'Hara, R.2    Matsuyama, S.S.3
  • 25
    • 84855585694 scopus 로고    scopus 로고
    • Autosomal recessive causes likely in early-onset Alzheimer disease
    • Wingo T.S., Lah J.J., Levey A.I., et al. Autosomal recessive causes likely in early-onset Alzheimer disease. Arch Neurol 2012, 69:59-64.
    • (2012) Arch Neurol , vol.69 , pp. 59-64
    • Wingo, T.S.1    Lah, J.J.2    Levey, A.I.3
  • 26
    • 33748588131 scopus 로고    scopus 로고
    • Early-onset Alzheimer disease in families with late-onset Alzheimer disease: a potential important subtype of familial Alzheimer disease
    • Brickell K.L., Steinbart E.J., Rumbaugh M., et al. Early-onset Alzheimer disease in families with late-onset Alzheimer disease: a potential important subtype of familial Alzheimer disease. Arch Neurol 2006, 63:1307-1311.
    • (2006) Arch Neurol , vol.63 , pp. 1307-1311
    • Brickell, K.L.1    Steinbart, E.J.2    Rumbaugh, M.3
  • 27
    • 79851483133 scopus 로고    scopus 로고
    • Meeting the mental health needs of the aging veteran population
    • Sorrell J.M., Durham S. Meeting the mental health needs of the aging veteran population. J Psychosoc Nurs Ment Health Serv 2011, 49:22-25.
    • (2011) J Psychosoc Nurs Ment Health Serv , vol.49 , pp. 22-25
    • Sorrell, J.M.1    Durham, S.2
  • 28
    • 77953306771 scopus 로고    scopus 로고
    • Posttraumatic stress disorder and risk of dementia among US veterans
    • Yaffe K., Vittinghoff E., Lindquist K., et al. Posttraumatic stress disorder and risk of dementia among US veterans. Arch Gen Psychiatry 2010, 67:608-613.
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 608-613
    • Yaffe, K.1    Vittinghoff, E.2    Lindquist, K.3
  • 29
    • 79961158069 scopus 로고    scopus 로고
    • Traumatic brain injury and amyloid-beta pathology: a link to Alzheimer's disease?
    • Johnson V.E., Stewart W., Smith D.H. Traumatic brain injury and amyloid-beta pathology: a link to Alzheimer's disease?. Nat Rev Neurosci 2010, 11:361-370.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 361-370
    • Johnson, V.E.1    Stewart, W.2    Smith, D.H.3
  • 30
    • 84863331086 scopus 로고    scopus 로고
    • Chronic traumatic encephalopathy: neurodegeneration following repetitive concussive and subconcussive brain trauma
    • Baugh C.M., Stamm J.M., Riley D.O., et al. Chronic traumatic encephalopathy: neurodegeneration following repetitive concussive and subconcussive brain trauma. Brain Imaging Behav 2012, 6:244-254.
    • (2012) Brain Imaging Behav , vol.6 , pp. 244-254
    • Baugh, C.M.1    Stamm, J.M.2    Riley, D.O.3
  • 31
    • 84865659788 scopus 로고    scopus 로고
    • Nonamnestic presentations of early-onset Alzheimer's disease
    • Mendez M.F., Lee A.S., Joshi A., et al. Nonamnestic presentations of early-onset Alzheimer's disease. Am J Alzheimers Dis Other Demen 2012, 27:413-420.
    • (2012) Am J Alzheimers Dis Other Demen , vol.27 , pp. 413-420
    • Mendez, M.F.1    Lee, A.S.2    Joshi, A.3
  • 32
    • 34848906841 scopus 로고    scopus 로고
    • Focal cortical presentations of Alzheimer's disease
    • Alladi S., Xuereb J., Bak T., et al. Focal cortical presentations of Alzheimer's disease. Brain 2007, 130:2636-2645.
    • (2007) Brain , vol.130 , pp. 2636-2645
    • Alladi, S.1    Xuereb, J.2    Bak, T.3
  • 33
    • 77950349494 scopus 로고    scopus 로고
    • Early-versus late-onset Alzheimer's disease: more than age alone
    • Koedam E.L., Lauffer V., van der Vlies A.E., et al. Early-versus late-onset Alzheimer's disease: more than age alone. J Alzheimers Dis 2010, 19:1401-1408.
    • (2010) J Alzheimers Dis , vol.19 , pp. 1401-1408
    • Koedam, E.L.1    Lauffer, V.2    van der Vlies, A.E.3
  • 34
    • 44349105859 scopus 로고    scopus 로고
    • Variability in cognitive presentation of Alzheimer's disease
    • Stopford C.L., Snowden J.S., Thompson J.C., et al. Variability in cognitive presentation of Alzheimer's disease. Cortex 2008, 44:185-195.
    • (2008) Cortex , vol.44 , pp. 185-195
    • Stopford, C.L.1    Snowden, J.S.2    Thompson, J.C.3
  • 35
    • 79956142378 scopus 로고    scopus 로고
    • The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • McKhann G.M., Knopman D.S., Chertkow H., et al. The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 2011, 7:263-269.
    • (2011) Alzheimers Dement , vol.7 , pp. 263-269
    • McKhann, G.M.1    Knopman, D.S.2    Chertkow, H.3
  • 37
    • 0036364359 scopus 로고    scopus 로고
    • The solved and unsolved mysteries of the genetics of early-onset Alzheimer's disease
    • Rogaeva E. The solved and unsolved mysteries of the genetics of early-onset Alzheimer's disease. Neuromolecular Med 2002, 2:1-10.
    • (2002) Neuromolecular Med , vol.2 , pp. 1-10
    • Rogaeva, E.1
  • 38
    • 84861488289 scopus 로고    scopus 로고
    • Early onset Alzheimer's disease is associated with a distinct neuropsychological profile
    • Smits L.L., Pijnenburg Y.A., Koedam E.L., et al. Early onset Alzheimer's disease is associated with a distinct neuropsychological profile. J Alzheimers Dis 2012, 30:101-108.
    • (2012) J Alzheimers Dis , vol.30 , pp. 101-108
    • Smits, L.L.1    Pijnenburg, Y.A.2    Koedam, E.L.3
  • 39
    • 84867140476 scopus 로고    scopus 로고
    • Brain networks in posterior cortical atrophy: a single case tractography study and literature review
    • Migliaccio R., Agosta F., Toba M.N., et al. Brain networks in posterior cortical atrophy: a single case tractography study and literature review. Cortex 2012, 48:1298-1309.
    • (2012) Cortex , vol.48 , pp. 1298-1309
    • Migliaccio, R.1    Agosta, F.2    Toba, M.N.3
  • 40
    • 79952823979 scopus 로고    scopus 로고
    • Classification of primary progressive aphasia and its variants
    • Gorno-Tempini M.L., Hillis A.E., Weintraub S., et al. Classification of primary progressive aphasia and its variants. Neurology 2011, 76:1006-1014.
    • (2011) Neurology , vol.76 , pp. 1006-1014
    • Gorno-Tempini, M.L.1    Hillis, A.E.2    Weintraub, S.3
  • 41
    • 80054880527 scopus 로고    scopus 로고
    • Posterior cortical atrophy: evidence for discrete syndromes of early-onset Alzheimer's disease
    • Tsai P.H., Teng E., Liu C., et al. Posterior cortical atrophy: evidence for discrete syndromes of early-onset Alzheimer's disease. Am J Alzheimers Dis Other Demen 2011, 26:413-418.
    • (2011) Am J Alzheimers Dis Other Demen , vol.26 , pp. 413-418
    • Tsai, P.H.1    Teng, E.2    Liu, C.3
  • 42
    • 0036277902 scopus 로고    scopus 로고
    • Posterior cortical atrophy: clinical characteristics and differences compared to Alzheimer's disease
    • Mendez M.F., Ghajarania M., Perryman K.M. Posterior cortical atrophy: clinical characteristics and differences compared to Alzheimer's disease. Dement Geriatr Cogn Disord 2002, 14:33-40.
    • (2002) Dement Geriatr Cogn Disord , vol.14 , pp. 33-40
    • Mendez, M.F.1    Ghajarania, M.2    Perryman, K.M.3
  • 43
    • 33646175716 scopus 로고    scopus 로고
    • What are we seeing? Is posterior cortical atrophy just Alzheimer disease?
    • Tang-Wai D., Mapstone M. What are we seeing? Is posterior cortical atrophy just Alzheimer disease?. Neurology 2006, 66:300-301.
    • (2006) Neurology , vol.66 , pp. 300-301
    • Tang-Wai, D.1    Mapstone, M.2
  • 44
    • 84857997213 scopus 로고    scopus 로고
    • Diagnostic criteria for corticobasal syndrome: a comparative study
    • Mathew R., Bak T.H., Hodges J.R. Diagnostic criteria for corticobasal syndrome: a comparative study. J Neurol Neurosurg Psychiatry 2012, 83:405-410.
    • (2012) J Neurol Neurosurg Psychiatry , vol.83 , pp. 405-410
    • Mathew, R.1    Bak, T.H.2    Hodges, J.R.3
  • 45
    • 84865835722 scopus 로고    scopus 로고
    • Differences between early and late-onset Alzheimer's disease in neuropsychological tests
    • Sa F., Pinto P., Cunha C., et al. Differences between early and late-onset Alzheimer's disease in neuropsychological tests. Front Neurol 2012, 3:81.
    • (2012) Front Neurol , vol.3 , pp. 81
    • Sa, F.1    Pinto, P.2    Cunha, C.3
  • 46
    • 0029976753 scopus 로고    scopus 로고
    • Clinical and neuropsychological differences between patients with earlier and later onset of Alzheimer's disease: a CERAD analysis, Part XII
    • Koss E., Edland S., Fillenbaum G., et al. Clinical and neuropsychological differences between patients with earlier and later onset of Alzheimer's disease: a CERAD analysis, Part XII. Neurology 1996, 46:136-141.
    • (1996) Neurology , vol.46 , pp. 136-141
    • Koss, E.1    Edland, S.2    Fillenbaum, G.3
  • 47
    • 34250312886 scopus 로고    scopus 로고
    • The accurate diagnosis of early-onset dementia
    • Mendez M.F. The accurate diagnosis of early-onset dementia. Int J Psychiatry Med 2006, 36:401-412.
    • (2006) Int J Psychiatry Med , vol.36 , pp. 401-412
    • Mendez, M.F.1
  • 48
    • 33947096956 scopus 로고    scopus 로고
    • The topography of grey matter involvement in early and late onset Alzheimer's disease
    • Frisoni G.B., Pievani M., Testa C., et al. The topography of grey matter involvement in early and late onset Alzheimer's disease. Brain 2007, 130:720-730.
    • (2007) Brain , vol.130 , pp. 720-730
    • Frisoni, G.B.1    Pievani, M.2    Testa, C.3
  • 49
    • 34347373501 scopus 로고    scopus 로고
    • Cognitive differences between early- and late-onset Alzheimer's disease
    • Licht E.A., McMurtray A.M., Saul R.E., et al. Cognitive differences between early- and late-onset Alzheimer's disease. Am J Alzheimers Dis Other Demen 2007, 22:218-222.
    • (2007) Am J Alzheimers Dis Other Demen , vol.22 , pp. 218-222
    • Licht, E.A.1    McMurtray, A.M.2    Saul, R.E.3
  • 50
    • 84857141740 scopus 로고    scopus 로고
    • Working memory, attention, and executive function in Alzheimer's disease and frontotemporal dementia
    • Stopford C.L., Thompson J.C., Neary D., et al. Working memory, attention, and executive function in Alzheimer's disease and frontotemporal dementia. Cortex 2012, 48:429-446.
    • (2012) Cortex , vol.48 , pp. 429-446
    • Stopford, C.L.1    Thompson, J.C.2    Neary, D.3
  • 51
    • 84872686497 scopus 로고    scopus 로고
    • Regional brain volume differences in symptomatic and pre-symptomatic carriers of familial Alzheimer's disease mutations
    • [Epub ahead of print].
    • Lee G.J., Lu P.H., Medina L.D., et al. Regional brain volume differences in symptomatic and pre-symptomatic carriers of familial Alzheimer's disease mutations. J Neurol Neurosurg Psychiatry 2012, [Epub ahead of print].
    • (2012) J Neurol Neurosurg Psychiatry
    • Lee, G.J.1    Lu, P.H.2    Medina, L.D.3
  • 52
    • 33750975078 scopus 로고    scopus 로고
    • Voxel-based analysis of PET amyloid ligand [11C]PIB uptake in Alzheimer disease
    • Kemppainen N.M., Aalto S., Wilson I.A., et al. Voxel-based analysis of PET amyloid ligand [11C]PIB uptake in Alzheimer disease. Neurology 2006, 67:1575-1580.
    • (2006) Neurology , vol.67 , pp. 1575-1580
    • Kemppainen, N.M.1    Aalto, S.2    Wilson, I.A.3
  • 53
    • 0037172826 scopus 로고    scopus 로고
    • Phases of A beta-deposition in the human brain and its relevance for the development of AD
    • Thal D.R., Rub U., Orantes M., et al. Phases of A beta-deposition in the human brain and its relevance for the development of AD. Neurology 2002, 58:1791-1800.
    • (2002) Neurology , vol.58 , pp. 1791-1800
    • Thal, D.R.1    Rub, U.2    Orantes, M.3
  • 54
    • 30444438344 scopus 로고    scopus 로고
    • Voxel-based morphometric comparison between early- and late-onset mild Alzheimer's disease and assessment of diagnostic performance of z score images
    • Ishii K., Kawachi T., Sasaki H., et al. Voxel-based morphometric comparison between early- and late-onset mild Alzheimer's disease and assessment of diagnostic performance of z score images. AJNR Am J Neuroradiol 2005, 26:333-340.
    • (2005) AJNR Am J Neuroradiol , vol.26 , pp. 333-340
    • Ishii, K.1    Kawachi, T.2    Sasaki, H.3
  • 55
    • 0038354732 scopus 로고    scopus 로고
    • Alzheimer's disease: differences in technetium-99m HMPAO SPECT scan findings between early onset and late onset dementia
    • Kemp P.M., Holmes C., Hoffmann S.M., et al. Alzheimer's disease: differences in technetium-99m HMPAO SPECT scan findings between early onset and late onset dementia. J Neurol Neurosurg Psychiatry 2003, 74:715-719.
    • (2003) J Neurol Neurosurg Psychiatry , vol.74 , pp. 715-719
    • Kemp, P.M.1    Holmes, C.2    Hoffmann, S.M.3
  • 56
    • 0026759348 scopus 로고
    • Atrophy of medial temporal lobes on MRI in "probable" Alzheimer's disease and normal ageing: diagnostic value and neuropsychological correlates
    • Scheltens P., Leys D., Barkhof F., et al. Atrophy of medial temporal lobes on MRI in "probable" Alzheimer's disease and normal ageing: diagnostic value and neuropsychological correlates. J Neurol Neurosurg Psychiatry 1992, 55:967-972.
    • (1992) J Neurol Neurosurg Psychiatry , vol.55 , pp. 967-972
    • Scheltens, P.1    Leys, D.2    Barkhof, F.3
  • 57
    • 77249098331 scopus 로고    scopus 로고
    • Increased metabolic vulnerability in early-onset Alzheimer's disease is not related to amyloid burden
    • Rabinovici G.D., Furst A.J., Alkalay A., et al. Increased metabolic vulnerability in early-onset Alzheimer's disease is not related to amyloid burden. Brain 2010, 133:512-528.
    • (2010) Brain , vol.133 , pp. 512-528
    • Rabinovici, G.D.1    Furst, A.J.2    Alkalay, A.3
  • 58
    • 33748689296 scopus 로고    scopus 로고
    • Four subgroups of Alzheimer's disease based on patterns of atrophy using VBM and a unique pattern for early onset disease
    • Shiino A., Watanabe T., Maeda K., et al. Four subgroups of Alzheimer's disease based on patterns of atrophy using VBM and a unique pattern for early onset disease. Neuroimage 2006, 33:17-26.
    • (2006) Neuroimage , vol.33 , pp. 17-26
    • Shiino, A.1    Watanabe, T.2    Maeda, K.3
  • 59
    • 79960145302 scopus 로고    scopus 로고
    • Temporoparietal atrophy: a marker of AD pathology independent of clinical diagnosis
    • Whitwell J.L., Jack C.R., Przybelski S.A., et al. Temporoparietal atrophy: a marker of AD pathology independent of clinical diagnosis. Neurobiol Aging 2011, 32:1531-1541.
    • (2011) Neurobiol Aging , vol.32 , pp. 1531-1541
    • Whitwell, J.L.1    Jack, C.R.2    Przybelski, S.A.3
  • 60
    • 84863560159 scopus 로고    scopus 로고
    • Early-onset Alzheimer disease clinical variants: multivariate analyses of cortical thickness
    • Ridgway G.R., Lehmann M., Barnes J., et al. Early-onset Alzheimer disease clinical variants: multivariate analyses of cortical thickness. Neurology 2012, 79:80-84.
    • (2012) Neurology , vol.79 , pp. 80-84
    • Ridgway, G.R.1    Lehmann, M.2    Barnes, J.3
  • 61
    • 72049128028 scopus 로고    scopus 로고
    • Clinical syndromes associated with posterior atrophy: early age at onset AD spectrum
    • Migliaccio R., Agosta F., Rascovsky K., et al. Clinical syndromes associated with posterior atrophy: early age at onset AD spectrum. Neurology 2009, 73:1571-1578.
    • (2009) Neurology , vol.73 , pp. 1571-1578
    • Migliaccio, R.1    Agosta, F.2    Rascovsky, K.3
  • 62
    • 84864802613 scopus 로고    scopus 로고
    • Ventral and dorsal visual streams in posterior cortical atrophy: a DT MRI study
    • Migliaccio R., Agosta F., Scola E., et al. Ventral and dorsal visual streams in posterior cortical atrophy: a DT MRI study. Neurobiol Aging 2012, 33:2572-2584.
    • (2012) Neurobiol Aging , vol.33 , pp. 2572-2584
    • Migliaccio, R.1    Agosta, F.2    Scola, E.3
  • 63
    • 36348967745 scopus 로고    scopus 로고
    • Precuneus atrophy in early-onset Alzheimer's disease: a morphometric structural MRI study
    • Karas G., Scheltens P., Rombouts S., et al. Precuneus atrophy in early-onset Alzheimer's disease: a morphometric structural MRI study. Neuroradiology 2007, 49:967-976.
    • (2007) Neuroradiology , vol.49 , pp. 967-976
    • Karas, G.1    Scheltens, P.2    Rombouts, S.3
  • 64
    • 84856975210 scopus 로고    scopus 로고
    • Alzheimer's pathology in primary progressive aphasia
    • Rohrer J.D., Rossor M.N., Warren J.D. Alzheimer's pathology in primary progressive aphasia. Neurobiol Aging 2012, 33:744-752.
    • (2012) Neurobiol Aging , vol.33 , pp. 744-752
    • Rohrer, J.D.1    Rossor, M.N.2    Warren, J.D.3
  • 65
    • 78650513587 scopus 로고    scopus 로고
    • EEG abnormalities in early and late onset Alzheimer's disease: understanding heterogeneity
    • de Waal H., Stam C.J., Blankenstein M.A., et al. EEG abnormalities in early and late onset Alzheimer's disease: understanding heterogeneity. J Neurol Neurosurg Psychiatry 2011, 82:67-71.
    • (2011) J Neurol Neurosurg Psychiatry , vol.82 , pp. 67-71
    • de Waal, H.1    Stam, C.J.2    Blankenstein, M.A.3
  • 66
    • 0025299234 scopus 로고
    • Alzheimer's disease. Age at onset and single-photon emission computed tomographic patterns of regional cerebral blood flow
    • Jagust W.J., Reed B.R., Seab J.P., et al. Alzheimer's disease. Age at onset and single-photon emission computed tomographic patterns of regional cerebral blood flow. Arch Neurol 1990, 47:628-633.
    • (1990) Arch Neurol , vol.47 , pp. 628-633
    • Jagust, W.J.1    Reed, B.R.2    Seab, J.P.3
  • 67
    • 23444440165 scopus 로고    scopus 로고
    • Glucose metabolism in early onset versus late onset Alzheimer's disease: an SPM analysis of 120 patients
    • Kim E.J., Cho S.S., Jeong Y., et al. Glucose metabolism in early onset versus late onset Alzheimer's disease: an SPM analysis of 120 patients. Brain 2005, 128:1790-1801.
    • (2005) Brain , vol.128 , pp. 1790-1801
    • Kim, E.J.1    Cho, S.S.2    Jeong, Y.3
  • 68
    • 0037102709 scopus 로고    scopus 로고
    • Differences in cerebral metabolic impairment between early and late onset types of Alzheimer's disease
    • Sakamoto S., Ishii K., Sasaki M., et al. Differences in cerebral metabolic impairment between early and late onset types of Alzheimer's disease. J Neurol Sci 2002, 200:27-32.
    • (2002) J Neurol Sci , vol.200 , pp. 27-32
    • Sakamoto, S.1    Ishii, K.2    Sasaki, M.3
  • 69
    • 6844265569 scopus 로고    scopus 로고
    • Age at onset and regional cerebral glucose metabolism in Alzheimer's disease
    • Yasuno F., Imamura T., Hirono N., et al. Age at onset and regional cerebral glucose metabolism in Alzheimer's disease. Dement Geriatr Cogn Disord 1998, 9:63-67.
    • (1998) Dement Geriatr Cogn Disord , vol.9 , pp. 63-67
    • Yasuno, F.1    Imamura, T.2    Hirono, N.3
  • 70
    • 0026512651 scopus 로고
    • Differences of regional cerebral glucose metabolism between presenile and senile dementia of Alzheimer type
    • Mielke R., Herholz K., Grond M., et al. Differences of regional cerebral glucose metabolism between presenile and senile dementia of Alzheimer type. Neurobiol Aging 1992, 13:93-98.
    • (1992) Neurobiol Aging , vol.13 , pp. 93-98
    • Mielke, R.1    Herholz, K.2    Grond, M.3
  • 71
    • 37249064623 scopus 로고    scopus 로고
    • Positron emission tomography facilitates diagnosis of early-onset Alzheimer's disease
    • McMurtray A.M., Licht E., Yeo T., et al. Positron emission tomography facilitates diagnosis of early-onset Alzheimer's disease. Eur Neurol 2008, 59:31-37.
    • (2008) Eur Neurol , vol.59 , pp. 31-37
    • McMurtray, A.M.1    Licht, E.2    Yeo, T.3
  • 72
    • 0026547582 scopus 로고
    • Familial Alzheimer's disease with the amyloid precursor protein position 717 mutation and sporadic Alzheimer's disease have the same cytoskeletal pathology
    • Lantos P.L., Luthert P.J., Hanger D., et al. Familial Alzheimer's disease with the amyloid precursor protein position 717 mutation and sporadic Alzheimer's disease have the same cytoskeletal pathology. Neurosci Lett 1992, 137:221-224.
    • (1992) Neurosci Lett , vol.137 , pp. 221-224
    • Lantos, P.L.1    Luthert, P.J.2    Hanger, D.3
  • 73
    • 0026665034 scopus 로고
    • Heterogeneity in Alzheimer's disease: progression rate segregated by distinct neuropsychological and cerebral metabolic profiles
    • Mann U.M., Mohr E., Gearing M., et al. Heterogeneity in Alzheimer's disease: progression rate segregated by distinct neuropsychological and cerebral metabolic profiles. J Neurol Neurosurg Psychiatry 1992, 55:956-959.
    • (1992) J Neurol Neurosurg Psychiatry , vol.55 , pp. 956-959
    • Mann, U.M.1    Mohr, E.2    Gearing, M.3
  • 74
    • 77949543957 scopus 로고    scopus 로고
    • Comparison of neuropsychological and FDG-PET findings between early- versus late-onset mild cognitive impairment: a five year longitudinal study
    • Kim S.H., Seo S.W., Yoon D.S., et al. Comparison of neuropsychological and FDG-PET findings between early- versus late-onset mild cognitive impairment: a five year longitudinal study. Dement Geriatr Cogn Disord 2010, 29:213-223.
    • (2010) Dement Geriatr Cogn Disord , vol.29 , pp. 213-223
    • Kim, S.H.1    Seo, S.W.2    Yoon, D.S.3
  • 75
    • 84867655566 scopus 로고    scopus 로고
    • Neuropsychological and neuroimaging markers in early versus late-onset Alzheimer's disease
    • Kaiser N.C., Melrose R.J., Collin Liu C., et al. Neuropsychological and neuroimaging markers in early versus late-onset Alzheimer's disease. Am J Alzheimer's Disease Other Dementias 2012, 27:520-529.
    • (2012) Am J Alzheimer's Disease Other Dementias , vol.27 , pp. 520-529
    • Kaiser, N.C.1    Melrose, R.J.2    Collin Liu, C.3
  • 76
    • 84863197449 scopus 로고    scopus 로고
    • Amyloid burden and metabolic function in early-onset Alzheimer's disease: parietal lobe involvement
    • Ossenkoppele R., Zwan M.D., Tolboom N., et al. Amyloid burden and metabolic function in early-onset Alzheimer's disease: parietal lobe involvement. Brain 2012, 135:2115-2125.
    • (2012) Brain , vol.135 , pp. 2115-2125
    • Ossenkoppele, R.1    Zwan, M.D.2    Tolboom, N.3
  • 77
    • 67651097594 scopus 로고    scopus 로고
    • Dissecting molecular mechanisms in the living brain of dementia patients
    • Barrio J.R., Satyamurthy N., Huang S.C., et al. Dissecting molecular mechanisms in the living brain of dementia patients. Acc Chem Res 2009, 42:842-850.
    • (2009) Acc Chem Res , vol.42 , pp. 842-850
    • Barrio, J.R.1    Satyamurthy, N.2    Huang, S.C.3
  • 78
    • 66549106850 scopus 로고    scopus 로고
    • Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's disease
    • Jack C.R., Lowe V.J., Weigand S.D., et al. Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's disease. Brain 2009, 132:1355-1365.
    • (2009) Brain , vol.132 , pp. 1355-1365
    • Jack, C.R.1    Lowe, V.J.2    Weigand, S.D.3
  • 79
    • 79960210779 scopus 로고    scopus 로고
    • Relationship of amyloid-beta burden with age-at-onset in Alzheimer disease
    • Choo I.H., Lee D.Y., Kim J.W., et al. Relationship of amyloid-beta burden with age-at-onset in Alzheimer disease. Am J Geriatr Psychiatry 2011, 19:627-634.
    • (2011) Am J Geriatr Psychiatry , vol.19 , pp. 627-634
    • Choo, I.H.1    Lee, D.Y.2    Kim, J.W.3
  • 80
    • 55849121534 scopus 로고    scopus 로고
    • Abeta amyloid and glucose metabolism in three variants of primary progressive aphasia
    • Rabinovici G.D., Jagust W.J., Furst A.J., et al. Abeta amyloid and glucose metabolism in three variants of primary progressive aphasia. Ann Neurol 2008, 64:388-401.
    • (2008) Ann Neurol , vol.64 , pp. 388-401
    • Rabinovici, G.D.1    Jagust, W.J.2    Furst, A.J.3
  • 81
    • 80054061066 scopus 로고    scopus 로고
    • Subtypes of progressive aphasia: application of the International Consensus Criteria and validation using beta-amyloid imaging
    • Leyton C.E., Villemagne V.L., Savage S., et al. Subtypes of progressive aphasia: application of the International Consensus Criteria and validation using beta-amyloid imaging. Brain 2011, 134:3030-3043.
    • (2011) Brain , vol.134 , pp. 3030-3043
    • Leyton, C.E.1    Villemagne, V.L.2    Savage, S.3
  • 82
    • 79959699255 scopus 로고    scopus 로고
    • Similar amyloid-beta burden in posterior cortical atrophy and Alzheimer's disease
    • de Souza L.C., Corlier F., Habert M.O., et al. Similar amyloid-beta burden in posterior cortical atrophy and Alzheimer's disease. Brain 2011, 134:2036-2043.
    • (2011) Brain , vol.134 , pp. 2036-2043
    • de Souza, L.C.1    Corlier, F.2    Habert, M.O.3
  • 83
    • 79958163751 scopus 로고    scopus 로고
    • Distinct clinical and metabolic deficits in PCA and AD are not related to amyloid distribution
    • Rosenbloom M.H., Alkalay A., Agarwal N., et al. Distinct clinical and metabolic deficits in PCA and AD are not related to amyloid distribution. Neurology 2011, 76:1789-1796.
    • (2011) Neurology , vol.76 , pp. 1789-1796
    • Rosenbloom, M.H.1    Alkalay, A.2    Agarwal, N.3
  • 84
    • 80051663321 scopus 로고    scopus 로고
    • Neuropathologically defined subtypes of Alzheimer's disease with distinct clinical characteristics: a retrospective study
    • Murray M.E., Graff-Radford N.R., Ross O.A., et al. Neuropathologically defined subtypes of Alzheimer's disease with distinct clinical characteristics: a retrospective study. Lancet Neurol 2011, 10:785-796.
    • (2011) Lancet Neurol , vol.10 , pp. 785-796
    • Murray, M.E.1    Graff-Radford, N.R.2    Ross, O.A.3
  • 85
    • 33846913643 scopus 로고    scopus 로고
    • Early-onset Alzheimer's disease is associated with greater pathologic burden
    • Marshall G.A., Fairbanks L.A., Tekin S., et al. Early-onset Alzheimer's disease is associated with greater pathologic burden. J Geriatr Psychiatry Neurol 2007, 20:29-33.
    • (2007) J Geriatr Psychiatry Neurol , vol.20 , pp. 29-33
    • Marshall, G.A.1    Fairbanks, L.A.2    Tekin, S.3
  • 86
    • 84860633148 scopus 로고    scopus 로고
    • Clinically concordant variations of Alzheimer pathology in aphasic versus amnestic dementia
    • Gefen T., Gasho K., Rademaker A., et al. Clinically concordant variations of Alzheimer pathology in aphasic versus amnestic dementia. Brain 2012, 135:1554-1565.
    • (2012) Brain , vol.135 , pp. 1554-1565
    • Gefen, T.1    Gasho, K.2    Rademaker, A.3
  • 87
    • 82355181107 scopus 로고    scopus 로고
    • TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's syndrome: association with age, hippocampal sclerosis and clinical phenotype
    • Davidson Y.S., Raby S., Foulds P.G., et al. TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's syndrome: association with age, hippocampal sclerosis and clinical phenotype. Acta Neuropathol 2011, 122:703-713.
    • (2011) Acta Neuropathol , vol.122 , pp. 703-713
    • Davidson, Y.S.1    Raby, S.2    Foulds, P.G.3
  • 88
    • 84861183657 scopus 로고    scopus 로고
    • Hippocampal-sparing Alzheimer's disease presenting as corticobasal syndrome
    • Malkani R.G., Dickson D.W., Simuni T. Hippocampal-sparing Alzheimer's disease presenting as corticobasal syndrome. Parkinsonism Relat Disord 2012, 18:683-685.
    • (2012) Parkinsonism Relat Disord , vol.18 , pp. 683-685
    • Malkani, R.G.1    Dickson, D.W.2    Simuni, T.3
  • 89
    • 40349116354 scopus 로고    scopus 로고
    • MRI patterns of atrophy associated with progression to AD in amnestic mild cognitive impairment
    • Whitwell J.L., Shiung M.M., Przybelski S.A., et al. MRI patterns of atrophy associated with progression to AD in amnestic mild cognitive impairment. Neurology 2008, 70:512-520.
    • (2008) Neurology , vol.70 , pp. 512-520
    • Whitwell, J.L.1    Shiung, M.M.2    Przybelski, S.A.3
  • 90
    • 80053654021 scopus 로고    scopus 로고
    • Prediction of MCI to AD conversion, via MRI, CSF biomarkers, and pattern classification
    • e19-27
    • Davatzikos C., Bhatt P., Shaw L.M., et al. Prediction of MCI to AD conversion, via MRI, CSF biomarkers, and pattern classification. Neurobiol Aging 2011, 32:2322. e19-27.
    • (2011) Neurobiol Aging , vol.32 , pp. 2322
    • Davatzikos, C.1    Bhatt, P.2    Shaw, L.M.3
  • 91
    • 70349884191 scopus 로고    scopus 로고
    • CSF biomarker levels in early and late onset Alzheimer's disease
    • Bouwman F.H., Schoonenboom N.S., Verwey N.A., et al. CSF biomarker levels in early and late onset Alzheimer's disease. Neurobiol Aging 2009, 30:1895-1901.
    • (2009) Neurobiol Aging , vol.30 , pp. 1895-1901
    • Bouwman, F.H.1    Schoonenboom, N.S.2    Verwey, N.A.3
  • 92
    • 77956405786 scopus 로고    scopus 로고
    • Could clinical profile influence CSF biomarkers in early-onset Alzheimer disease?
    • Koric L., Felician O., Guedj E., et al. Could clinical profile influence CSF biomarkers in early-onset Alzheimer disease?. Alzheimer Dis Assoc Disord 2010, 24:278-283.
    • (2010) Alzheimer Dis Assoc Disord , vol.24 , pp. 278-283
    • Koric, L.1    Felician, O.2    Guedj, E.3
  • 93
    • 84865529158 scopus 로고    scopus 로고
    • Clinical and biomarker changes in dominantly inherited Alzheimer's disease
    • Bateman R.J., Xiong C., Benzinger T.L., et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. N Engl J Med 2012, 367:795-804.
    • (2012) N Engl J Med , vol.367 , pp. 795-804
    • Bateman, R.J.1    Xiong, C.2    Benzinger, T.L.3
  • 94
    • 84855304100 scopus 로고    scopus 로고
    • Cerebrospinal fluid levels of beta-amyloid 1-42, but not of tau, are fully changed already 5 to 10 years before the onset of Alzheimer dementia
    • Buchhave P., Minthon L., Zetterberg H., et al. Cerebrospinal fluid levels of beta-amyloid 1-42, but not of tau, are fully changed already 5 to 10 years before the onset of Alzheimer dementia. Arch Gen Psychiatry 2012, 69:98-106.
    • (2012) Arch Gen Psychiatry , vol.69 , pp. 98-106
    • Buchhave, P.1    Minthon, L.2    Zetterberg, H.3
  • 95
    • 72049130805 scopus 로고    scopus 로고
    • Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
    • Jack C.R., Knopman D.S., Jagust W.J., et al. Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade. Lancet Neurol 2010, 9:119-128.
    • (2010) Lancet Neurol , vol.9 , pp. 119-128
    • Jack, C.R.1    Knopman, D.S.2    Jagust, W.J.3
  • 96
    • 79956098248 scopus 로고    scopus 로고
    • Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • Sperling R.A., Aisen P.S., Beckett L.A., et al. Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 2011, 7:280-292.
    • (2011) Alzheimers Dement , vol.7 , pp. 280-292
    • Sperling, R.A.1    Aisen, P.S.2    Beckett, L.A.3
  • 97
    • 79957458672 scopus 로고    scopus 로고
    • Neural correlates of cognitive impairment in posterior cortical atrophy
    • Kas A., de Souza L.C., Samri D., et al. Neural correlates of cognitive impairment in posterior cortical atrophy. Brain 2011, 134:1464-1478.
    • (2011) Brain , vol.134 , pp. 1464-1478
    • Kas, A.1    de Souza, L.C.2    Samri, D.3
  • 98
    • 57449106343 scopus 로고    scopus 로고
    • Evidence for a frontoparietal control system revealed by intrinsic functional connectivity
    • Vincent J.L., Kahn I., Snyder A.Z., et al. Evidence for a frontoparietal control system revealed by intrinsic functional connectivity. J Neurophysiol 2008, 100:3328-3342.
    • (2008) J Neurophysiol , vol.100 , pp. 3328-3342
    • Vincent, J.L.1    Kahn, I.2    Snyder, A.Z.3
  • 99
    • 84858068396 scopus 로고    scopus 로고
    • Functional integration of parietal lobe activity in early Alzheimer disease
    • Jacobs H.I., Van Boxtel M.P., Heinecke A., et al. Functional integration of parietal lobe activity in early Alzheimer disease. Neurology 2012, 78:352-360.
    • (2012) Neurology , vol.78 , pp. 352-360
    • Jacobs, H.I.1    Van Boxtel, M.P.2    Heinecke, A.3
  • 100
    • 84856971964 scopus 로고    scopus 로고
    • Different beta-amyloid oligomer assemblies in Alzheimer brains correlate with age of disease onset and impaired cholinergic activity
    • Bao F., Wicklund L., Lacor P.N., et al. Different beta-amyloid oligomer assemblies in Alzheimer brains correlate with age of disease onset and impaired cholinergic activity. Neurobiol Aging 2012, 33:e1-e13.
    • (2012) Neurobiol Aging , vol.33
    • Bao, F.1    Wicklund, L.2    Lacor, P.N.3
  • 101
    • 84866089622 scopus 로고    scopus 로고
    • Distinct patterns of antiamyloid-beta antibodies in typical and atypical Alzheimer disease: distinct patterns of anti-abeta antibodies and AD
    • Dorothee G., Bottlaender M., Moukari E., et al. Distinct patterns of antiamyloid-beta antibodies in typical and atypical Alzheimer disease: distinct patterns of anti-abeta antibodies and AD. Arch Neurol 2012, 69:1181-1185.
    • (2012) Arch Neurol , vol.69 , pp. 1181-1185
    • Dorothee, G.1    Bottlaender, M.2    Moukari, E.3
  • 102
    • 79955449442 scopus 로고    scopus 로고
    • Young-onset dementia: a review of the literature and what it means for clinicians
    • Hunt D.C. Young-onset dementia: a review of the literature and what it means for clinicians. J Psychosoc Nurs Ment Health Serv 2011, 49:28-33.
    • (2011) J Psychosoc Nurs Ment Health Serv , vol.49 , pp. 28-33
    • Hunt, D.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.