DNA hypermethylation in colorectal neoplasms and inflammatory bowel disease: A mini review

Inflammopharmacology

Volumn 14, Issue 5-6, 2006, Pages 204-206

  Maeda, O ^a   Ando, T ^a   Watanabe, O ^a   Ishiguro, K ^a   Ohmiya, N ^a   Niwa, Y ^a   Goto, H ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Colorectal cancer; Fecal DNA; Hypermethylation; Inflammatory bowel disease

Indexed keywords

DNA;

CANCER CELL; CANCER GENETICS; CANCER RISK; CARCINOGENESIS; COLON POLYP; COLORECTAL TUMOR; CONFERENCE PAPER; DNA METHYLATION; ENTERITIS; GENE EXPRESSION; GENE SILENCING; HUMAN; MICROSATELLITE INSTABILITY; POINT MUTATION; PRIORITY JOURNAL; TUMOR GROWTH; TUMOR SUPPRESSOR GENE;

ANIMALS; COLORECTAL NEOPLASMS; DNA METHYLATION; HUMANS; INFLAMMATORY BOWEL DISEASES;

EID: 33845890020     PISSN: 09254692     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10787-006-1540-6     Document Type: Conference Paper

References (30)

1. Ahlquist, D. A., Skoletsky, J. E., Boynton, K. A. et al. (2000). Colorectal cancer screening by detection of altered human DNA in stool: feasibility of a multitarget assay panel, Gastroenterology 119, 1219-1227.
2. Baylin, S. B., Herman, J. G., Graff, J. R. et al. (1998). Alterations in DNA methylation: a fundamental aspect of neoplasia, Adv. Cancer Res. 72, 141-196.
3. Belshaw, N. J., Elliott, G. O., Williams, E. A. et al. (2004). Use of DNA from human stools to detect aberrant CpG island methylation of genes implicated in colorectal cancer, Cancer Epidemiol Biomarkers Prev. 13, 1495-1501.
4. Bird, A. P. (1986). CpG-rich islands and the function of DNA methylation. Nature 321, 209-213.
5. Brenner, D. E. and Rennert, G. (2005). Fecal DNA biomarkers for the detection of colorectal neoplasia: attractive, but is it feasible?, J. Natl. Cancer Inst. 97, 1107-1109.
6. Calistri, D., Rengucci, C., Bocchini, R. et al. (2003). Fecal multiple molecular tests to detect colorectal cancer in stool, Clin. Gastroenterol. Hepatol. 1, 377-383.
7. Chen, W. D., Han, Z. J., Skoletsky, J. et al. (2005). Detection in fecal DNA of colon cancer-specific methylation of the nonexpressed vimentin gene, J. Natl. Cancer Inst. 97, 1124-1132.
8. Ekbom, A., Helmick, C., Zack, M. et al. (1990). Ulcerative colitis and colorectal cancer. A population-based study, N. Engl. J. Med. 323, 1228-1233.
9. Fleisher, A. S., Esteller, M., Wang, S. et al. (1999). Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability, Cancer Res. 59, 1090-1095.
10. Fujii, S., Tominaga, K., Kitajima, K. et al. (2005). Methylation of the oestrogen receptor gene in non-neoplastic epithelium as a marker of colorectal neoplasia risk in longstanding and extensive ulcerative colitis, Gut 54, 1287-1292.
11. Gilbert, J., Gore, S. D., Herman, J. G. et al. (2004). The clinical application of targeting cancer through histone acetylation and hypomethylation, Clin. Cancer Res. 10, 4589-4596.
12. Herman, J. G., Merlo, A., Mao, L. et al. (1995). Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers, Cancer Res. 55, 4525-4530.
13. Herman, J. G., Umar, A., Polyak, K. et al. (1998). Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma, Proc. Natl. Acad Sci. USA 95, 6870-6875.
14. Imperiale, T. F., Ransohoff, D. F., Itzkowitz, S. H. et al. (2004). Fecal DNA versus fecal occult blood for colorectal-cancer screening in an average-risk population, N. Engl. J. Med. 351, 2704-2714.
15. Issa, J. P., Ahuja, N., Toyota, M. et al. (2001). Accelerated age-related CpG island methylation in ulcerative colitis, Cancer Res. 61, 3573-3577.
16. Issa, J. P., Ottaviano, Y. L., Celano, P. et al. (1994). Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon, Nat. Genet. 7, 536-540.
17. Lenhard, K., Bommer, G. T., Asutay, S. et al. (2005). Analysis of promoter methylation in stool: a novel method for the detection of colorectal cancer, Clin. Gastroenterol Hepatol. 3, 142-149.
18. Maeda, O., Ando, T., Watanabe, O., et al. (2006). DNA hypermethylation in colorectal polyps and inflammatory bowel disease, Digestion 73 (suppl 2), 40
19. Matsumura, S., Oue, N., Ito, R. et al. (2003). The promoter methylation status of the DNA repair gene O6-methylguanine-DNA methyltransferase in ulcerative colitis, Virchows Arch. 443, 518-523.
20. Müller, H. M., Oberwalder, M., Fiegl, H. et al. (2004). Methylation changes in faecal DNA: a marker for colorectal cancer screening? Lancet 363, 1283-1285.
21. Osborn, N. K., Zou, H., Molina, J. R. et al. (2006). Aberrant methylation of the eyes absent 4 gene in ulcerative colitis-associated dysplasia, Clin. Gastroenterol Hepatol. 4, 212-218.
22. Petko, Z., Ghiassi, M., Shuber, A. et al. (2005). Aberrantly methylated CDKN2A, MGMT, and MLH1 in colon polyps and in fecal DNA from patients with colorectal polyps, Clin. Cancer Res. 11, 1203-1209.
23. Sakai, T., Toguchida, J., Ohtani, N. et al. (1991). Allele-specific hypermethylation of the retinoblastoma tumor-suppressor gene, Am J. Hum. Genet. 48, 880-888.
24. Sato, F., Harpaz, N., Shibata, D. et al. (2002a). Hypermethylation of the p14(ARF) gene in ulcerative colitis-associated colorectal carcinogenesis, Cancer Res. 62, 1148-1151.
25. Sato, F., Shibata, D., Harpaz, N. et al. (2002b). Aberrant methylation of the HPP1 gene in ulcerative colitis-associated colorectal carcinoma. Cancer Res. 62, 6820-6822.
26. Sharrard, R. M., Royds, J. A., Rogers, S. et al. (1992). Patterns of methylation of the c-myc gene in human colorectal cancer progression, Br. J. Cancer 65, 667-672.
27. Sidransky, D., Tokino, T., Hamilton, S. R. et al. (1992). Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors. Science 256, 102-105.
28. Tagore, K. S., Lawson, M. J., Yucaitis, J. A. et al. (2003). Sensitivity and specificity of a stool DNA multitarget assay panel for the detection of advanced colorectal neoplasia, Clin. Colorectal Cancer. 3, 47-53.
29. Toyota, M., Ahuja, N., Suzuki, H. et al. (1999). Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype, Cancer Res. 59, 5438-5442.
30. Wong, D. J., Barrett, M. T., Stoger, R. et al. (1997). p16INK4a promoter is hypermethylated at a high frequency in esophageal adenocarcinomas, Cancer Res. 57, 2619-2622.