STAT1 activation by venous malformations mutant Tie2-R849W antagonizes VEGF-A-mediated angiogenic response partly via reduced bFGF production

Angiogenesis

Volumn 16, Issue 1, 2013, Pages 207-222

  Huang, Yi Hsien ^a   Wu, Ming Ping ^b,c   Pan, Shin Chen ^d   Su, Wu Chou ^a   Chen, Yi Wen ^a   Wu, Li Wha ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b CHI MEI MEDICAL CENTER   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

STAT1; STAT3; Tie2; Tie2 R849W; Venous malformations

Indexed keywords

ANGIOPOIETIN RECEPTOR; FIBROBLAST GROWTH FACTOR 2; MATRIGEL; SHORT HAIRPIN RNA; STAT1 PROTEIN; TYROSINE; VASCULOTROPIN A;

ARTICLE; BINDING SITE; BLOOD VESSEL; CELL FUNCTION; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EMBRYO; ENDOTHELIUM CELL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN TISSUE; NEUROPHYSIOLOGICAL RECRUITMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; TRANSCRIPTION INITIATION SITE; VEIN MALFORMATION;

BASE SEQUENCE; CELL MOVEMENT; CELL NUCLEUS; ENDOTHELIAL CELLS; FIBROBLAST GROWTH FACTOR 2; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; MYOCYTES, SMOOTH MUSCLE; NEOVASCULARIZATION, PHYSIOLOGIC; NEUTRALIZATION TESTS; PHOSPHORYLATION; PHOSPHOTYROSINE; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN TRANSPORT; RECEPTOR, TIE-2; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR MALFORMATIONS;

EID: 84871613282     PISSN: 09696970     EISSN: 15737209     Source Type: Journal    
DOI: 10.1007/s10456-012-9313-x     Document Type: Article

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