Functional analysis of a mutant form of the receptor tyrosine kinase Tie2 causing venous malformations

Journal of Molecular Medicine

Volumn 83, Issue 1, 2005, Pages 58-63

  Morris, Paul N ^a,e   Dunmore, Benjamin J ^b   Tadros, Amir ^a   Marchuk, Douglas A ^c   Darland, Diane C ^d   D'Amore, Patricia A ^d   Brindle, Nicholas P J ^a,f  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c DUKE UNIVERSITY   (United States)

^d SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^e University of Leicester ^*

^f UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Apoptosis; Endothelial cell; Tie2

Indexed keywords

ANGIOPOIETIN RECEPTOR; MUTANT PROTEIN; PROTEIN TYROSINE KINASE;

APOPTOSIS; ARTICLE; CELL MIGRATION; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MUTAGENESIS; MUTANT; PROTEIN EXPRESSION; PROTEIN FUNCTION; SMOOTH MUSCLE FIBER; VEIN MALFORMATION; WILD TYPE;

AMINO ACID SUBSTITUTION; APOPTOSIS; ENDOTHELIUM, VASCULAR; HUMANS; POINT MUTATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, TIE-2; SIGNAL TRANSDUCTION; VEINS;

EID: 12844251216     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-004-0601-9     Document Type: Article

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