-
2
-
-
70049112901
-
Guidelines for the diagnosis and treatment of pulmonary hypertension: The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT)
-
Galiè N, Hoeper MM, Humbert M, et al. Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur Heart J. 2009 ; 30 (20). 2493-2537
-
(2009)
Eur Heart J
, vol.30
, Issue.20
, pp. 2493-2537
-
-
Galiè, N.1
Hoeper, M.M.2
Humbert, M.3
-
3
-
-
62749192201
-
A meta-analysis of randomized controlled trials in pulmonary arterial hypertension
-
Galiè N, Manes A, Negro L, Palazzini M, Bacchi-Reggiani ML, Branzi A. A meta-analysis of randomized controlled trials in pulmonary arterial hypertension. Eur Heart J. 2009 ; 30 (4). 394-403
-
(2009)
Eur Heart J
, vol.30
, Issue.4
, pp. 394-403
-
-
Galiè, N.1
Manes, A.2
Negro, L.3
Palazzini, M.4
Bacchi-Reggiani, M.L.5
Branzi, A.6
-
4
-
-
75149192272
-
Nitric oxide, oxidative stress and inflammation in pulmonary arterial hypertension
-
Crosswhite P, Sun Z. Nitric oxide, oxidative stress and inflammation in pulmonary arterial hypertension. J Hypertens. 2010 ; 28 (2). 201-212
-
(2010)
J Hypertens
, vol.28
, Issue.2
, pp. 201-212
-
-
Crosswhite, P.1
Sun, Z.2
-
5
-
-
34548415037
-
The importance of endothelin-1 for vascular dysfunction in cardiovascular disease
-
Böhm F, Pernow J. The importance of endothelin-1 for vascular dysfunction in cardiovascular disease. Cardiovasc Res. 2007 ; 76 (1). 8-18
-
(2007)
Cardiovasc Res
, vol.76
, Issue.1
, pp. 8-18
-
-
Böhm, F.1
Pernow, J.2
-
6
-
-
70349260424
-
Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats
-
Csiszar A, Labinskyy N, Olson S, et al. Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats. Hypertension. 2009 ; 54 (3). 668-675
-
(2009)
Hypertension
, vol.54
, Issue.3
, pp. 668-675
-
-
Csiszar, A.1
Labinskyy, N.2
Olson, S.3
-
7
-
-
10744220901
-
Serotonin receptor antagonist inhibits monocrotaline-induced pulmonary hypertension and prolongs survival in rats
-
Hironaka E, Hongo M, Sakai A, et al. Serotonin receptor antagonist inhibits monocrotaline-induced pulmonary hypertension and prolongs survival in rats. Cardiovasc Res. 2003 ; 60 (3). 692-699
-
(2003)
Cardiovasc Res
, vol.60
, Issue.3
, pp. 692-699
-
-
Hironaka, E.1
Hongo, M.2
Sakai, A.3
-
8
-
-
77952192354
-
Idiopathic pulmonary arterial hypertension
-
Firth AL, Mandel J, Yuan JX. Idiopathic pulmonary arterial hypertension. Dis Model Mech. 2010 ; 3 (5-6). 268-273
-
(2010)
Dis Model Mech
, vol.3
, Issue.56
, pp. 268-273
-
-
Firth, A.L.1
Mandel, J.2
Yuan, J.X.3
-
9
-
-
33846013945
-
ATP-sensitive potassium channel openers and 2,3-dimethyl-2-butylamine derivatives
-
Wang H, Tang Y, Wang L, Long CL, Zhang YL. ATP-sensitive potassium channel openers and 2,3-dimethyl-2-butylamine derivatives. Curr Med Chem. 2007 ; 14 (2). 133-155
-
(2007)
Curr Med Chem
, vol.14
, Issue.2
, pp. 133-155
-
-
Wang, H.1
Tang, Y.2
Wang, L.3
Long, C.L.4
Zhang, Y.L.5
-
10
-
-
59849087929
-
Activation of ATP-sensitive potassium channels protects vascular endothelial cells from hypertension and renal injury induced by hyperuricemia
-
Long CL, Qin XC, Pan ZY, et al. Activation of ATP-sensitive potassium channels protects vascular endothelial cells from hypertension and renal injury induced by hyperuricemia. J Hypertens. 2008 ; 26 (12). 2326-2338
-
(2008)
J Hypertens
, vol.26
, Issue.12
, pp. 2326-2338
-
-
Long, C.L.1
Qin, X.C.2
Pan, Z.Y.3
-
11
-
-
77958498187
-
Activation of SUR2B/Kir6.1 subtype of adenosine triphosphate-sensitive potassium channel improves pressure overload induced cardiac remodeling via protecting endothelial function
-
Tang Y, Long CL, Wang RH, Cui W, Wang H. Activation of SUR2B/Kir6.1 subtype of adenosine triphosphate-sensitive potassium channel improves pressure overload induced cardiac remodeling via protecting endothelial function. J Cardiovasc Pharmacol. 2010 ; 56 (4). 345-353
-
(2010)
J Cardiovasc Pharmacol
, vol.56
, Issue.4
, pp. 345-353
-
-
Tang, Y.1
Long, C.L.2
Wang, R.H.3
Cui, W.4
Wang, H.5
-
12
-
-
14344259289
-
A new ATP-sensitive potassium channel opener reduces blood pressure and reverses cardiovascular remodeling in experimental hypertension
-
Wang H, Long CL, Zhang YL. A new ATP-sensitive potassium channel opener reduces blood pressure and reverses cardiovascular remodeling in experimental hypertension. J Pharmacol Exp Ther. 2005 ; 312 (3). 1326-1333
-
(2005)
J Pharmacol Exp Ther
, vol.312
, Issue.3
, pp. 1326-1333
-
-
Wang, H.1
Long, C.L.2
Zhang, Y.L.3
-
13
-
-
77957603729
-
Targeting hypertension with a new ATP sensitive potassium channel opener iptakalim
-
Pan Z, Huang J, Cui W, Long C, Zhang Y, Wang H. Targeting hypertension with a new ATP sensitive potassium channel opener iptakalim. J Cardiovasc Pharmacol. 2010 ; 56 (3). 215-228
-
(2010)
J Cardiovasc Pharmacol
, vol.56
, Issue.3
, pp. 215-228
-
-
Pan, Z.1
Huang, J.2
Cui, W.3
Long, C.4
Zhang, Y.5
Wang, H.6
-
14
-
-
0037282533
-
Pharmacological characteristics of the novel antihypertensive drug, iptakalim hydrochloride, and its molecular mechanisms
-
Pharmacological characteristics of the novel antihypertensive drug, iptakalim hydrochloride, and its molecular mechanisms. Drug Dev Res. 2003 ; 58: 65-68
-
(2003)
Drug Dev Res
, vol.58
, pp. 65-68
-
-
-
15
-
-
67651124964
-
KATP activation prevents progression of cardiac hypertrophy to failure induced by pressure overload via protecting endothelial function
-
Gao S, Long CL, Wang RH, Wang H. KATP activation prevents progression of cardiac hypertrophy to failure induced by pressure overload via protecting endothelial function. Cardiovasc Res. 2009 ; 83 (3). 444-456
-
(2009)
Cardiovasc Res
, vol.83
, Issue.3
, pp. 444-456
-
-
Gao, S.1
Long, C.L.2
Wang, R.H.3
Wang, H.4
-
16
-
-
4243059647
-
Effects of iptakalim hydrochloride, a novel KATP channel opener, on pulmonary vascular remodeling in hypoxic rats
-
Xie WP, Wang H, Wang H, Hu G. Effects of iptakalim hydrochloride, a novel KATP channel opener, on pulmonary vascular remodeling in hypoxic rats. Life Sci. 2004 ; 75 (17). 2065-2076
-
(2004)
Life Sci
, vol.75
, Issue.17
, pp. 2065-2076
-
-
Xie, W.P.1
Wang, H.2
Wang, H.3
Hu, G.4
-
17
-
-
15744397784
-
Anti-proliferating effect of iptakalim, a novel KATP channel opener, in cultured rabbit pulmonary arterial smooth muscle cells
-
Xie W, Wang H, Ding J, Wang H, Hu G.. Anti-proliferating effect of iptakalim, a novel KATP channel opener, in cultured rabbit pulmonary arterial smooth muscle cells. Eur J Pharmacol. 2005 ; 511 (2-3). 81-87
-
(2005)
Eur J Pharmacol
, vol.511
, Issue.23
, pp. 81-87
-
-
Xie, W.1
Wang, H.2
Ding, J.3
Wang, H.4
Hu, G.5
-
18
-
-
40149089375
-
Iptakalim inhibited endothelin-1-induced proliferation of human pulmonary arterial smooth muscle cells through the activation of KATP channel
-
Zhu Y, Zhang S, Xie W, Li Q, Zhou Y, Wang H. Iptakalim inhibited endothelin-1-induced proliferation of human pulmonary arterial smooth muscle cells through the activation of KATP channel. Vasc Pharmacol. 2008 ; 48 (2-3). 92-99
-
(2008)
Vasc Pharmacol
, vol.48
, Issue.23
, pp. 92-99
-
-
Zhu, Y.1
Zhang, S.2
Xie, W.3
Li, Q.4
Zhou, Y.5
Wang, H.6
-
19
-
-
71949129187
-
Animal models of pulmonary arterial hypertension: The hope for etiological discovery and pharmacological cure
-
Stenmark KR, Meyrick B, Galie N, Mooi WJ, McMurtry IF. Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure. Am J Physiol Lung Cell Mol Physiol. 2009 ; 297 (6). L1013 - L1032
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.297
, Issue.6
-
-
Stenmark, K.R.1
Meyrick, B.2
Galie, N.3
Mooi, W.J.4
McMurtry, I.F.5
-
20
-
-
34247899006
-
Animal models of pulmonary arterial hypertension
-
Naeije R, Dewachter L. Animal models of pulmonary arterial hypertension. Rev Mal Respir. 2007 ; 24 (4 pt 1). 481-496
-
(2007)
Rev Mal Respir
, vol.24
, Issue.4 PART 1
, pp. 481-496
-
-
Naeije, R.1
Dewachter, L.2
-
21
-
-
0043028479
-
Inflammation in pulmonary arterial hypertension
-
Dorfmüller P, Perros F, Balabanian K, Humbert M. Inflammation in pulmonary arterial hypertension. Eur Respir J. 2003 ; 22 (2). 358-363
-
(2003)
Eur Respir J
, vol.22
, Issue.2
, pp. 358-363
-
-
Dorfmüller, P.1
Perros, F.2
Balabanian, K.3
Humbert, M.4
-
22
-
-
0032474287
-
Endothelin A receptor blockade improves nitric oxide-mediated vasodilation in monocrotaline-induced pulmonary hypertension
-
Prié S, Stewart DJ, Dupuis J. Endothelin A receptor blockade improves nitric oxide-mediated vasodilation in monocrotaline-induced pulmonary hypertension. Circulation. 1998 ; 97 (21). 2169-2174
-
(1998)
Circulation
, vol.97
, Issue.21
, pp. 2169-2174
-
-
Prié, S.1
Stewart, D.J.2
Dupuis, J.3
-
23
-
-
33644541826
-
Genistein, a phytoestrogen, attenuates monocrotaline-induced pulmonary hypertension
-
Homma N, Morio Y, Takahashi H, et al. Genistein, a phytoestrogen, attenuates monocrotaline-induced pulmonary hypertension. Respiration. 2006 ; 73 (1). 105-112
-
(2006)
Respiration
, vol.73
, Issue.1
, pp. 105-112
-
-
Homma, N.1
Morio, Y.2
Takahashi, H.3
-
24
-
-
73349135641
-
Tadalafil, a long-acting inhibitor of PDE5, improves pulmonary hemodynamics and survival rate of monocrotaline-induced pulmonary artery hypertension in rats
-
Sawamura F, Kato M, Fujita K, Nakazawa T, Beardsworth A. Tadalafil, a long-acting inhibitor of PDE5, improves pulmonary hemodynamics and survival rate of monocrotaline-induced pulmonary artery hypertension in rats. J Pharmacol Sci. 2009 ; 111 (3). 235-243
-
(2009)
J Pharmacol Sci
, vol.111
, Issue.3
, pp. 235-243
-
-
Sawamura, F.1
Kato, M.2
Fujita, K.3
Nakazawa, T.4
Beardsworth, A.5
-
25
-
-
33846117876
-
Protecting endothelial function: A novel therapeutic target of ATP-sensitive potassium channel openers
-
Minamino T, Hori M. Protecting endothelial function: a novel therapeutic target of ATP-sensitive potassium channel openers. Cardiovasc Res. 2007 ; 73 (3). 448-449
-
(2007)
Cardiovasc Res
, vol.73
, Issue.3
, pp. 448-449
-
-
Minamino, T.1
Hori, M.2
-
26
-
-
33846116157
-
A new ATP-sensitive potassium channel opener protects endothelial function in cultured aortic endothelial cells
-
Wang H, Long C, Duan Z, Shi C, Jia G, Zhang Y. A new ATP-sensitive potassium channel opener protects endothelial function in cultured aortic endothelial cells. Cardiovasc Res. 2007 ; 73 (3). 497-503
-
(2007)
Cardiovasc Res
, vol.73
, Issue.3
, pp. 497-503
-
-
Wang, H.1
Long, C.2
Duan, Z.3
Shi, C.4
Jia, G.5
Zhang, Y.6
-
28
-
-
38149109703
-
Recent advances in natriuretic peptide research
-
Woodard Ge, Rosado JA.. Recent advances in natriuretic peptide research. J Cell Mol Med. 2007 ; 11 (6). 1263-1271
-
(2007)
J Cell Mol Med
, vol.11
, Issue.6
, pp. 1263-1271
-
-
Ge, W.1
Rosado, J.A.2
-
29
-
-
0345707647
-
Regulatory effects of iNOS on acute lung inflammatory responses in mice
-
Speyer CL, Neff TA, Warner RL, et al. Regulatory effects of iNOS on acute lung inflammatory responses in mice. Am J Pathol. 2003 ; 163 (6). 2319-2328
-
(2003)
Am J Pathol
, vol.163
, Issue.6
, pp. 2319-2328
-
-
Speyer, C.L.1
Neff, T.A.2
Warner, R.L.3
-
30
-
-
72749124664
-
Mediators released from LPS-challenged lungs induce inflammatory responses in liver vascular endothelial cells and neutrophilic leukocytes
-
Markovic N, McCaig LA, Stephen J, et al. Mediators released from LPS-challenged lungs induce inflammatory responses in liver vascular endothelial cells and neutrophilic leukocytes. Am J Physiol Gastrointest Liver Physiol. 2009 ; 297 (6). G1066 - G1076
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.297
, Issue.6
-
-
Markovic, N.1
McCaig, L.A.2
Stephen, J.3
-
31
-
-
20344365090
-
Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats
-
Guignabert C, Raffestin B, Benferhat R, et al. Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats. Circulation. 2005 ; 111 (21). 2812-2819
-
(2005)
Circulation
, vol.111
, Issue.21
, pp. 2812-2819
-
-
Guignabert, C.1
Raffestin, B.2
Benferhat, R.3
-
32
-
-
0033564747
-
Nitric oxide synthases in the failing human heart: A doubled-edged sword?
-
Drexler H. Nitric oxide synthases in the failing human heart: a doubled-edged sword?. Circulation. 1999 ; 99 (23). 2972-2975
-
(1999)
Circulation
, vol.99
, Issue.23
, pp. 2972-2975
-
-
Drexler, H.1
-
33
-
-
0027418514
-
Porcine ventricular endocardial cells in culture express the inducible form of nitric oxide synthase
-
Smith JA, Radomski MW, Schulz R, Moncada S, Lewis MJ. Porcine ventricular endocardial cells in culture express the inducible form of nitric oxide synthase. Br J Pharmacol. 1993 ; 108 (4). 1107-1110
-
(1993)
Br J Pharmacol
, vol.108
, Issue.4
, pp. 1107-1110
-
-
Smith, J.A.1
Radomski, M.W.2
Schulz, R.3
Moncada, S.4
Lewis, M.J.5
-
34
-
-
0030754628
-
Inhibition of constitutive nitric oxide synthase (NOS) by nitric oxide generated by inducible NOS after lipopolysaccharide administration provokes renal dysfunction in rats
-
Schwartz D, Mendonca M, Schwartz I, et al. Inhibition of constitutive nitric oxide synthase (NOS) by nitric oxide generated by inducible NOS after lipopolysaccharide administration provokes renal dysfunction in rats. J Clin Invest. 1997 ; 100 (2). 439-448
-
(1997)
J Clin Invest
, vol.100
, Issue.2
, pp. 439-448
-
-
Schwartz, D.1
Mendonca, M.2
Schwartz, I.3
-
35
-
-
68249150556
-
Serial noninvasive assessment of apoptosis during right ventricular disease progression in rats
-
Campian ME, Verberne HJ, Hardziyenka M, et al. Serial noninvasive assessment of apoptosis during right ventricular disease progression in rats. J Nucl Med. 2009 ; 50 (8). 1371-1377
-
(2009)
J Nucl Med
, vol.50
, Issue.8
, pp. 1371-1377
-
-
Campian, M.E.1
Verberne, H.J.2
Hardziyenka, M.3
-
36
-
-
0033593596
-
Modulation of cytokine-induced cardiac myocyte apoptosis by nitric oxide, Bak, and Bcl-x
-
Ing DJ, Zang J, Dzau VJ, Webster KA, Bishopric NH. Modulation of cytokine-induced cardiac myocyte apoptosis by nitric oxide, Bak, and Bcl-x. Circ Res. 1999 ; 84 (1). 21-33
-
(1999)
Circ Res
, vol.84
, Issue.1
, pp. 21-33
-
-
Ing, D.J.1
Zang, J.2
Dzau, V.J.3
Webster, K.A.4
Bishopric, N.H.5
-
37
-
-
63849121398
-
Role of oxidative and nitrosative stress biomarkers in chronic heart failure
-
Eleuteri E, Magno F, Gnemmi I, et al. Role of oxidative and nitrosative stress biomarkers in chronic heart failure. Front Biosci. 2009 ; 14: 2230-2237
-
(2009)
Front Biosci
, vol.14
, pp. 2230-2237
-
-
Eleuteri, E.1
Magno, F.2
Gnemmi, I.3
-
38
-
-
77649337086
-
Role of apoptosis in pulmonary hypertension: From experimental models to clinical trials
-
Jurasz P, Courtman D, Babaie S, Stewart DJ. Role of apoptosis in pulmonary hypertension: from experimental models to clinical trials. Pharmacol Ther. 2010 ; 126 (1). 1-8
-
(2010)
Pharmacol Ther
, vol.126
, Issue.1
, pp. 1-8
-
-
Jurasz, P.1
Courtman, D.2
Babaie, S.3
Stewart, D.J.4
-
39
-
-
67649844313
-
Inflammation, growth factors, and pulmonary vascular remodeling
-
Hassoun PM, Mouthon L, Barberà JA, et al. Inflammation, growth factors, and pulmonary vascular remodeling. J Am Coll Cardiol. 2009 ; 54 (1 suppl). S10 - S19
-
(2009)
J Am Coll Cardiol
, vol.54
, Issue.1 SUPPL.
-
-
Hassoun, P.M.1
Mouthon, L.2
Barberà, J.A.3
-
40
-
-
77951742414
-
L-arginine enhances nitrative stress and exacerbates tumor necrosis factor-alpha toxicity to human endothelial cells in culture: Prevention by propofol
-
Xia Z, Luo T, Liu HM, et al. L-arginine enhances nitrative stress and exacerbates tumor necrosis factor-alpha toxicity to human endothelial cells in culture: prevention by propofol. J Cardiovasc Pharmacol. 2010 ; 55 (4). 358-367
-
(2010)
J Cardiovasc Pharmacol
, vol.55
, Issue.4
, pp. 358-367
-
-
Xia, Z.1
Luo, T.2
Liu, H.M.3
-
41
-
-
77957125679
-
Peroxynitrite mediates right-ventricular dysfunction in nitric oxide-exposed juvenile rats
-
Jankov RP, Lewis P, Kantores C, et al. Peroxynitrite mediates right-ventricular dysfunction in nitric oxide-exposed juvenile rats. Free Radic Biol Med. 2010 ; 49 (9). 1453-1467
-
(2010)
Free Radic Biol Med
, vol.49
, Issue.9
, pp. 1453-1467
-
-
Jankov, R.P.1
Lewis, P.2
Kantores, C.3
-
42
-
-
8644277006
-
Reactive oxygen species in vascular biology: Implications in hypertension
-
Touyz RM, Schiffrin EL. Reactive oxygen species in vascular biology: implications in hypertension. Histochem Cell Biol. 2004 ; 122 (4). 339-352
-
(2004)
Histochem Cell Biol
, vol.122
, Issue.4
, pp. 339-352
-
-
Touyz, R.M.1
Schiffrin, E.L.2
-
43
-
-
25144453937
-
NADPH oxidase and endothelial cell function
-
Ray R, Shah AM. NADPH oxidase and endothelial cell function. Clin Sci (Lond). 2005 ; 109 (3). 217-226
-
(2005)
Clin Sci (Lond)
, vol.109
, Issue.3
, pp. 217-226
-
-
Ray, R.1
Shah, A.M.2
-
44
-
-
34547828784
-
Right-ventricular failure is associated with increased mitochondrial complex II activity and production of reactive oxygen species
-
Redout EM, Wagner MJ, Zuidwijk MJ, et al. Right-ventricular failure is associated with increased mitochondrial complex II activity and production of reactive oxygen species. Cardiovasc Res. 2007 ; 75 (4). 770-781
-
(2007)
Cardiovasc Res
, vol.75
, Issue.4
, pp. 770-781
-
-
Redout, E.M.1
Wagner, M.J.2
Zuidwijk, M.J.3
|