Acute Effects of Pomegranate Extract on Postprandial Lipaemia, Vascular Function and Blood Pressure

Plant Foods for Human Nutrition

Volumn 67, Issue 4, 2012, Pages 351-357

  Mathew, Aarati Susan ^a   Capel Williams, Gabriella M ^a   Berry, Sarah E E ^a   Hall, Wendy L ^a,b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Blood pressure; Polyphenols; Pomegranate; Postprandial lipaemia; Vascular function

Indexed keywords

LYTHRACEAE;

CHOLESTEROL; ELLAGITANNIN; PLANT EXTRACT; POLYPHENOL; TANNIN; TRIACYLGLYCEROL;

ADOLESCENT; ADULT; ARTICLE; BLOOD; BLOOD PRESSURE; CARDIOVASCULAR FUNCTION; CHEMISTRY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG EFFECT; GLUCOSE BLOOD LEVEL; HUMAN; HYPERLIPIDEMIA; LIPID DIET; LYTHRACEAE; MALE; PHYSIOLOGY; POSTPRANDIAL STATE; PULSE RATE; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; YOUNG ADULT;

ADOLESCENT; ADULT; BLOOD GLUCOSE; BLOOD PRESSURE; CARDIOVASCULAR PHYSIOLOGICAL PHENOMENA; CHOLESTEROL; CROSS-OVER STUDIES; DIET, HIGH-FAT; HUMANS; HYDROLYZABLE TANNINS; HYPERLIPIDEMIAS; MALE; PLANT EXTRACTS; POLYPHENOLS; POSTPRANDIAL PERIOD; PULSE; PUNICACEAE; SINGLE-BLIND METHOD; TRIGLYCERIDES; YOUNG ADULT;

EID: 84871457204     PISSN: 09219668     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11130-012-0318-9     Document Type: Article

References (25)

1. Clifford MN, Scalbert A (2000) Ellagitannins - nature, occurrence and dietary burden. J Sci Food Agric 80: 1118-1125.
2. Gil MI, Tomás-Barberán FA, Hess-Pierce B, Holcroft DM, Kader AA (2000) Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing. J Agric Food Chem 48: 4581-4589.
3. Mastrodi Salgado J, Baroni Ferreira TR, de Oliveira Biazotto F, Dos Santos Dias CT (2012) Increased antioxidant content in juice enriched with dried extract of pomegranate (Punica granatum) peel. Plant Foods Hum Nutr 67: 39-43.
4. Heber D (2011) Pomegranate ellagitannins. In: Benzie IFF, Wachtel-Galor S (eds), Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press; 2011. Chapter 10.
5. Seeram NP, Zhang Y, McKeever R, Henning SM, Lee RP, Suchard MA, Li Z, Chen S, Thames G, Zerlin A, Nguyen M, Wang D, Dreher M, Heber D (2008) Pomegranate juice and extracts provide similar levels of plasma and urinary ellagitannin metabolites in human subjects. J Med Food 11: 390-394.
6. Seeram NP, Lee R, Heber D (2004) Bioavailability of ellagic acid in human plasma after consumption of ellagitannins from pomegranate (Punica granatum L.) juice. Clin Chim Acta 348: 63-68.
7. Gonzalez-Barrio R, Borges G, Mullen W, Crozier A (2010) Bioavailability of anthocyanins and ellagitannins following consumption of raspberries by healthy humans and subjects with an ileostomy. J Agric Food Chem 58: 3933-3939.
8. Larrosa M, Garcia-Conesa MT, Espin JC, Tomas-Barberan FA (2010) Ellagitannins, ellagic acid and vascular health. Mol Aspects Med 31: 513-539.
9. Seeram NP, Henning SM, Zhang Y, Suchard M, Li Z, Heber D (2006) Pomegranate juice ellagitannin metabolites are present in human plasma and some persist in urine for up to 48 hours. J Nutr 136: 2481-2485.
10. Chong MF, Macdonald R, Lovegrove JA (2010) Fruit polyphenols and CVD risk: A review of human intervention studies. Br J Nutr 104(Suppl 3): S28-S39.
11. McDougall GJ, Kulkarni NN, Stewart D (2008) Current developments on the inhibitory effects of berry polyphenols on digestive enzymes. Biofactors 34: 73-80.
12. Kondo H, Hashizume K, Shibuya Y, Hase T, Murase T (2011) Identification of diacylglycerol acyltransferase inhibitors from Rosa centifolia petals. Lipids 46: 691-700.
13. Heber D, Seeram NP, Wyatt H, Henning SM, Zhang Y, Ogden LG, Dreher M, Hill JO (2007) Safety and antioxidant activity of a pomegranate ellagitannin-enriched polyphenol dietary supplement in overweight individuals with increased waist size. J Agric Food Chem 55: 10050-10054.
14. Millasseau SC, Kelly RP, Ritter JM, Chowienczyk PJ (2003) The vascular impact of aging and vasoactive drugs: Comparison of two digital volume pulse measurements. Am J Hypertens 16: 467-472.
15. Chowienczyk PJ, Kelly RP, MacCallum H, Millasseau SC, Andersson TL, Gosling RG, Ritter JM, Anggard EE (1999) Photoplethysmographic assessment of pulse wave reflection: Blunted response to endothelium-dependent beta2-adrenergic vasodilation in type II diabetes mellitus. J Am Coll Cardiol 34: 2007-2014.
16. Lairon D, Lopez-Miranda J, Williams C (2007) Methodology for studying postprandial lipid metabolism. Eur J Clin Nutr 61: 1145-1161.
17. Robertson MD, Mason AO, Frayn KN (2002) Timing of vagal stimulation affects postprandial lipid metabolism in humans. Am J Clin Nutr 76: 71-77.
18. Rontoyanni VG, Hall WL, Pombo-Rodrigues S, Appleton A, Chung R, Sanders TA (2012) A comparison of the changes in cardiac output and systemic vascular resistance during exercise following high-fat meals containing DHA or EPA. Br J Nutr 108: 492-499.
19. Rontoyanni VG, Chowienczyk PJ, Sanders TA (2010) Postprandial lipaemia does not affect resting haemodynamic responses but does influence cardiovascular reactivity to dynamic exercise. Br J Nutr 104: 863-871.
20. Hall WL, Sanders KA, Sanders TA, Chowienczyk PJ (2008) A high-fat meal enriched with eicosapentaenoic acid reduces postprandial arterial stiffness measured by digital volume pulse analysis in healthy men. J Nutr 138: 287-291.
21. O'Donovan D, Horowitz M, Russo A, Feinle-Bisset C, Murolo N, Gentilcore D, Wishart JM, Morris HA, Jones KL (2004) Effects of lipase inhibition on gastric emptying of, and on the glycaemic, insulin and cardiovascular responses to, a high-fat/carbohydrate meal in type 2 diabetes. Diabetologia 47: 2208-2214.
22. Tai K, Gentilcore D, Jones KL, Banh L, Gilja OH, Hammond AJ, Feinle-Bisset C, Horowitz M, Chapman IM (2011) Orlistat accentuates the fat-induced fall in blood pressure in older adults. Br J Nutr 106: 417-424.
23. Lynn A, Hamadeh H, Leung WC, Russell JM, Barker ME (2012) Effects of pomegranate juice supplementation on pulse wave velocity and blood pressure in healthy young and middle-aged men and women. Plant Foods Hum Nutr 67: 309-314.
24. Aviram M, Dornfeld L (2001) Pomegranate juice consumption inhibits serum angiotensin converting enzyme activity and reduces systolic blood pressure. Atherosclerosis 158: 195-198.
25. Aviram M, Rosenblat M, Gaitini D, Nitecki S, Hoffman A, Dornfeld L, Volkova N, Presser D, Attias J, Liker H, Hayek T (2004) Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation. Clin Nutr 23: 423-433.