Antibodies against the extracellular domain of human Notch1 receptor reveal the critical role of epidermal-growth-factor-like repeats 25-26 in ligand binding and receptor activation

Biochemical Journal

Volumn 449, Issue 2, 2013, Pages 519-530

  Sharma, Ankur ^a   Rangarajan, Annapoorni ^a   Dighe, Rajan R ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

Abruptex; Antibody; Epidermal growth factor like repeat (ELR); Jagged Delta like; Ligand binding site; Notch1

Indexed keywords

ANTIBODY; CALCIUM; FC RECEPTOR; JAGGED1; MONOCLONAL ANTIBODY; NOTCH1 RECEPTOR; POLYCLONAL ANTIBODY;

ARTICLE; BINDING AFFINITY; BINDING SITE; DISSOCIATION; FLOW CYTOMETRY; FUCOSYLATION; GLYCOSYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIGAND BINDING; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; SURFACE PLASMON RESONANCE;

AMINO ACID SEQUENCE; ANTIBODIES; BINDING SITES; BINDING, COMPETITIVE; CALCIUM; EPIDERMAL GROWTH FACTOR; FLOW CYTOMETRY; GLYCOSYLATION; HEK293 CELLS; HUMANS; IMMUNOBLOTTING; KINETICS; LIGANDS; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDES; PROTEIN BINDING; RECEPTOR, NOTCH1; REPETITIVE SEQUENCES, AMINO ACID; SEQUENCE HOMOLOGY, AMINO ACID;

METAZOA;

EID: 84871448957     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20121153     Document Type: Article

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