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Volumn 195, Issue 1, 2013, Pages 24-32

How to improve housing conditions of laboratory animals: The possibilities of environmental refinement

Author keywords

Animal welfare; Environmental refinement; Housing conditions; Laboratory animals; Standardisation

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL HOUSING; ANIMAL TESTING REFINEMENT; ANIMAL WELFARE; ANIMAL WELLBEING; CAT; DOG; ENVIRONMENTAL ENRICHMENT; ENVIRONMENTAL FACTOR; ETHICS; EXPERIMENTAL ANIMAL; GERBIL; GUINEA PIG; HAMSTER; INTEGRATION; NONHUMAN; PHYSIOLOGY; PRIMATE; RABBIT; REVIEW; SPECIES DIFFERENTIATION; VETERINARY MEDICINE; ANIMAL; SPECIES DIFFERENCE; STANDARDS;

EID: 84871413039     PISSN: 10900233     EISSN: 15322971     Source Type: Journal    
DOI: 10.1016/j.tvjl.2012.09.023     Document Type: Review
Times cited : (98)

References (82)
  • 3
    • 17144373320 scopus 로고    scopus 로고
    • Environmental enrichment for laboratory rodents and rabbits: Requirements of rodents, rabbits and research
    • Enrichment Strategies for Laboratory Animals
    • Baumans V. Environmental enrichment for laboratory rodents and rabbits: Requirements of rodents, rabbits and research. ILAR Journal 2005, 46:162-170.
    • (2005) ILAR Journal , vol.46 , pp. 162-170
    • Baumans, V.1
  • 4
    • 84871418937 scopus 로고    scopus 로고
    • The impact of the environment on laboratory animals
    • Universidade Federal de Sao Paulo, Brazil,
    • Baumans, V., 2010a. The impact of the environment on laboratory animals. In: Animal models as tools in ethical biomedical research, Universidade Federal de Sao Paulo, Brazil, pp. 15-23.
    • (2010) In: Animal models as tools in ethical biomedical research , pp. 15-23
    • Baumans, V.1
  • 5
    • 85179218673 scopus 로고    scopus 로고
    • Animal needs and environmental refinement
    • CRC Press, London, B. Howard, T. Nevalainen, G. Perretta (Eds.) The COST Manual of Laboratory Animal Care and Use
    • Baumans V., Augustsson H., Perretta G. Animal needs and environmental refinement. Refinement, Reduction and Research 2010, 75-100. CRC Press, London. B. Howard, T. Nevalainen, G. Perretta (Eds.).
    • (2010) Refinement, Reduction and Research , pp. 75-100
    • Baumans, V.1    Augustsson, H.2    Perretta, G.3
  • 6
    • 84860412121 scopus 로고    scopus 로고
    • Standardisation of environmental enrichment for laboratory mice and rats: Utilisation, practicality and variation in experimental results
    • Baumans V., Van Loo P.L.P., Pham T.M. Standardisation of environmental enrichment for laboratory mice and rats: Utilisation, practicality and variation in experimental results. Scandinavian Journal of Laboratory Animal Science 2010, 37:1-14.
    • (2010) Scandinavian Journal of Laboratory Animal Science , vol.37 , pp. 1-14
    • Baumans, V.1    Van Loo, P.L.P.2    Pham, T.M.3
  • 9
    • 0002591287 scopus 로고    scopus 로고
    • Effects of experience and environment on the developing and mature brain: Implications for laboratory animal housing
    • Benefiel A.C., Greenough W.T. Effects of experience and environment on the developing and mature brain: Implications for laboratory animal housing. ILAR Journal 1998, 39:5-11.
    • (1998) ILAR Journal , vol.39 , pp. 5-11
    • Benefiel, A.C.1    Greenough, W.T.2
  • 10
    • 84871409173 scopus 로고    scopus 로고
    • The Laboratory Rat: A Natural History. Oxford University. (accessed 25 September 2012).
    • Berdoy, M., 2002. The Laboratory Rat: A Natural History. Oxford University. (accessed 25 September 2012). http://ratlife.org.
    • (2002)
    • Berdoy, M.1
  • 13
    • 0033523043 scopus 로고    scopus 로고
    • Genetics of mouse behavior: Interacitons with laboratory environment
    • Crabbe J.C., Wahlsten D., Dudek B.C. Genetics of mouse behavior: Interacitons with laboratory environment. Science 1999, 284:1670-1672.
    • (1999) Science , vol.284 , pp. 1670-1672
    • Crabbe, J.C.1    Wahlsten, D.2    Dudek, B.C.3
  • 16
    • 84871451236 scopus 로고    scopus 로고
    • FELASA (Federation of European Laboratory Animal Science Associations)
    • Working Group Report. (accessed 22 February 2012).
    • FELASA (Federation of European Laboratory Animal Science Associations), 2006. Working Group Standardization of Enrichment, Working Group Report. (accessed 22 February 2012). http://www.lal.org.uk/pdffiles/FELASA_Enrichment_2006.pdf.
    • (2006) Working Group Standardization of Enrichment
  • 17
    • 78149499566 scopus 로고    scopus 로고
    • Cage-induced stereotypies in female ICR CD-1 mice do not correlate with recurrent perseveration
    • Gross A.N., Engel A.K., Richter S.H., Garner J.P., Wuerbel H. Cage-induced stereotypies in female ICR CD-1 mice do not correlate with recurrent perseveration. Behavioral Brain Research 2011, 216:613-620.
    • (2011) Behavioral Brain Research , vol.216 , pp. 613-620
    • Gross, A.N.1    Engel, A.K.2    Richter, S.H.3    Garner, J.P.4    Wuerbel, H.5
  • 18
    • 78751700064 scopus 로고    scopus 로고
    • A guide to defining and implementing protocols for the welfare assessment of laboratory animals: 11th report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement
    • Hawkins P., Morton D.B., Burman O., Dennison N., Honess P., Jennings M., Lane S., Middleton V., Roughan J.V., Wells S., Westwood K. A guide to defining and implementing protocols for the welfare assessment of laboratory animals: 11th report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement. Laboratory Animals 2011, 45:1-13.
    • (2011) Laboratory Animals , vol.45 , pp. 1-13
    • Hawkins, P.1    Morton, D.B.2    Burman, O.3    Dennison, N.4    Honess, P.5    Jennings, M.6    Lane, S.7    Middleton, V.8    Roughan, J.V.9    Wells, S.10    Westwood, K.11
  • 19
    • 0035173711 scopus 로고    scopus 로고
    • Evaluation of individually ventilated cage systems for laboratory rodents: Cage environment and animal health aspects
    • Hoglund A.U., Renstroem A. Evaluation of individually ventilated cage systems for laboratory rodents: Cage environment and animal health aspects. Laboratory Animals 2001, 35:51-70.
    • (2001) Laboratory Animals , vol.35 , pp. 51-70
    • Hoglund, A.U.1    Renstroem, A.2
  • 21
    • 1642550903 scopus 로고    scopus 로고
    • Comfortable quarters for dogs in research institutions
    • Animal Welfare Institute, Washington, V. Reinhardt, A. Reinhardt (Eds.)
    • Hubrecht R.C. Comfortable quarters for dogs in research institutions. Comfortable Quarters for Laboratory Animals 2002, 56-64. Animal Welfare Institute, Washington. Ninth Ed. V. Reinhardt, A. Reinhardt (Eds.).
    • (2002) Comfortable Quarters for Laboratory Animals , pp. 56-64
    • Hubrecht, R.C.1
  • 24
    • 17144425358 scopus 로고    scopus 로고
    • Environmental enrichment for laboratory rodents
    • Enrichment Strategies for Laboratory Animals
    • Hutchinson E., Avery A., VandeWoude S. Environmental enrichment for laboratory rodents. ILAR Journal 2005, 46:148-161.
    • (2005) ILAR Journal , vol.46 , pp. 148-161
    • Hutchinson, E.1    Avery, A.2    VandeWoude, S.3
  • 25
    • 82955193701 scopus 로고    scopus 로고
    • Environmental enrichment compensates for the effects of stress on disease progression in Tg2576 mice, an Alzheimer's disease model
    • Jeong Y.H., Kim J.M., Lee S.H., Kim H.S., Suh Y.H. Environmental enrichment compensates for the effects of stress on disease progression in Tg2576 mice, an Alzheimer's disease model. Journal of Neurochemistry 2011, 119:1282-1293.
    • (2011) Journal of Neurochemistry , vol.119 , pp. 1282-1293
    • Jeong, Y.H.1    Kim, J.M.2    Lee, S.H.3    Kim, H.S.4    Suh, Y.H.5
  • 26
    • 65549138895 scopus 로고    scopus 로고
    • Refinements in husbandry, care and common procedures for non-human primates. 9th report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement
    • JWGR (Joint Working Group on Refinement)
    • JWGR (Joint Working Group on Refinement) Refinements in husbandry, care and common procedures for non-human primates. 9th report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement. Laboratory Animals 2009, 43:1-47.
    • (2009) Laboratory Animals , vol.43 , pp. 1-47
  • 28
    • 27944460724 scopus 로고    scopus 로고
    • Method developments and assessments of animal welfare in IVC systems
    • Thesis the Royal Veterinary and Agricultural University, Frederiksberg, Denmark.
    • Krohn, T.C., 2002. Method developments and assessments of animal welfare in IVC systems. Thesis the Royal Veterinary and Agricultural University, Frederiksberg, Denmark.
    • (2002)
    • Krohn, T.C.1
  • 29
    • 0037394948 scopus 로고    scopus 로고
    • The impact of cage ventilation on rats housed in IVC systems
    • Krohn T.C., Hansen A.K., Dragsted N. The impact of cage ventilation on rats housed in IVC systems. Laboratory Animals 2003, 37:85-93.
    • (2003) Laboratory Animals , vol.37 , pp. 85-93
    • Krohn, T.C.1    Hansen, A.K.2    Dragsted, N.3
  • 30
    • 80054710822 scopus 로고    scopus 로고
    • How do rats respond to playing radio in the animal facility?
    • Krohn T.C., Salling B., Kornerup Hansen A. How do rats respond to playing radio in the animal facility?. Laboratory Animals 2011, 45:141-144.
    • (2011) Laboratory Animals , vol.45 , pp. 141-144
    • Krohn, T.C.1    Salling, B.2    Kornerup Hansen, A.3
  • 31
    • 80052531716 scopus 로고    scopus 로고
    • Evaluation of social and physical enrichment in modulation of behavioural phenotype in C57BL/6J female mice
    • Kulesskaya N., Rauvala H., Voikar V. Evaluation of social and physical enrichment in modulation of behavioural phenotype in C57BL/6J female mice. PLoS ONE 2011, 6:e24755.
    • (2011) PLoS ONE , vol.6
    • Kulesskaya, N.1    Rauvala, H.2    Voikar, V.3
  • 32
    • 0001798209 scopus 로고    scopus 로고
    • Chronic intermittent stress: a model for the study of long-term stressors
    • CAB International, Oxon, UK
    • Ladewig J. Chronic intermittent stress: a model for the study of long-term stressors. The Biology of Animal Stress 2000, 159-169. CAB International, Oxon, UK.
    • (2000) The Biology of Animal Stress , pp. 159-169
    • Ladewig, J.1
  • 33
    • 2442488908 scopus 로고    scopus 로고
    • From house mouse to mouse house: The behavioural biology of free-living Mus musculus and its implications in the laboratory
    • Latham N., Mason G. From house mouse to mouse house: The behavioural biology of free-living Mus musculus and its implications in the laboratory. Applied Animal Behaviour Science 2004, 86:251-289.
    • (2004) Applied Animal Behaviour Science , vol.86 , pp. 251-289
    • Latham, N.1    Mason, G.2
  • 35
    • 0003035684 scopus 로고    scopus 로고
    • Isolator rodent caging systems (state of the art): A critical view
    • Lipman N.S. Isolator rodent caging systems (state of the art): A critical view. Contemporary Topics in Laboratory Animal Science 1999, 38:9-17.
    • (1999) Contemporary Topics in Laboratory Animal Science , vol.38 , pp. 9-17
    • Lipman, N.S.1
  • 37
    • 17144422477 scopus 로고    scopus 로고
    • Environmental enrichment for nonhuman primates: Theory and application
    • Enrichment Strategies for Laboratory Animals
    • Lutz C.K., Novak M.A. Environmental enrichment for nonhuman primates: Theory and application. ILAR Journal 2005, 46:178-191.
    • (2005) ILAR Journal , vol.46 , pp. 178-191
    • Lutz, C.K.1    Novak, M.A.2
  • 38
    • 0031962359 scopus 로고    scopus 로고
    • Operant studies to determine the strength of preference in laboratory rats for nest-boxes and nesting materials
    • Manser C.E., Broom D.M., Overend P., Morris T.H. Operant studies to determine the strength of preference in laboratory rats for nest-boxes and nesting materials. Laboratory Animals 1998, 32:36-41.
    • (1998) Laboratory Animals , vol.32 , pp. 36-41
    • Manser, C.E.1    Broom, D.M.2    Overend, P.3    Morris, T.H.4
  • 39
    • 0035978954 scopus 로고    scopus 로고
    • Suppression of brain aging and neurodegenerative disorders by dietary restriction and environmental enrichment: Molecular mechanisms
    • Mattson M.P., Duan W., Lee J., Guo Z. Suppression of brain aging and neurodegenerative disorders by dietary restriction and environmental enrichment: Molecular mechanisms. Mechanisms of Ageing and Development 2001, 122:757.
    • (2001) Mechanisms of Ageing and Development , vol.122 , pp. 757
    • Mattson, M.P.1    Duan, W.2    Lee, J.3    Guo, Z.4
  • 41
    • 0035164617 scopus 로고    scopus 로고
    • Estimates of appropriate number of rats: Interaction with housing environment
    • Mering S., Kaliste-Korhonen E., Nevalainen T. Estimates of appropriate number of rats: Interaction with housing environment. Laboratory Animals 2001, 35:80-90.
    • (2001) Laboratory Animals , vol.35 , pp. 80-90
    • Mering, S.1    Kaliste-Korhonen, E.2    Nevalainen, T.3
  • 42
    • 78349291120 scopus 로고    scopus 로고
    • Clinical pathology and cardiovascular paprmeters are not influenced by housing rats under increased environmental complexity
    • Mikkelsen L.F., Sorensen D.B., Krohn T., Lauritzen B., Dragstedt N., Hansen A.K., Ottesen J.L. Clinical pathology and cardiovascular paprmeters are not influenced by housing rats under increased environmental complexity. AnimalWelfare 2010, 19:449-460.
    • (2010) AnimalWelfare , vol.19 , pp. 449-460
    • Mikkelsen, L.F.1    Sorensen, D.B.2    Krohn, T.3    Lauritzen, B.4    Dragstedt, N.5    Hansen, A.K.6    Ottesen, J.L.7
  • 44
    • 0027504206 scopus 로고
    • Refinements in rabbit husbandry-Second report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement (JWGR)
    • Morton D.B. Refinements in rabbit husbandry-Second report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement (JWGR). Laboratory Animals 1993, 27:301-329.
    • (1993) Laboratory Animals , vol.27 , pp. 301-329
    • Morton, D.B.1
  • 45
    • 0344683235 scopus 로고    scopus 로고
    • NRC (National Research Council),The National Academies Press, Washington, DC
    • NRC (National Research Council) Guide for the Care and Use of Laboratory Animals 2011, The National Academies Press, Washington, DC. Eighth Ed.
    • (2011) Guide for the Care and Use of Laboratory Animals
  • 46
    • 17144377275 scopus 로고
    • Environmental enrichment: Increasing the biological relevance of captive environments
    • Newberry R.C. Environmental enrichment: Increasing the biological relevance of captive environments. Applied Animal Behaviour Science 1995, 44:229-243.
    • (1995) Applied Animal Behaviour Science , vol.44 , pp. 229-243
    • Newberry, R.C.1
  • 47
    • 0036069688 scopus 로고    scopus 로고
    • Improving housing conditions for laboratory mice: A review of 'environmental enrichment'
    • Olsson I.A.S., Dahlborn K. Improving housing conditions for laboratory mice: A review of 'environmental enrichment'. Laboratory Animals 2002, 3:243-270.
    • (2002) Laboratory Animals , vol.3 , pp. 243-270
    • Olsson, I.A.S.1    Dahlborn, K.2
  • 49
    • 33847122924 scopus 로고    scopus 로고
    • More than numbers matter: The effect of social factors on behaviour and welfare of laboratory rodents and non-human primates
    • Olsson I.A.S., Westlund K. More than numbers matter: The effect of social factors on behaviour and welfare of laboratory rodents and non-human primates. Applied Animal Behaviour Science 2007, 103:229-254.
    • (2007) Applied Animal Behaviour Science , vol.103 , pp. 229-254
    • Olsson, I.A.S.1    Westlund, K.2
  • 52
    • 0030957691 scopus 로고    scopus 로고
    • Happy animals make good science
    • Poole T.B. Happy animals make good science. Laboratory Animals 1997, 31:116-124.
    • (1997) Laboratory Animals , vol.31 , pp. 116-124
    • Poole, T.B.1
  • 53
    • 0001973790 scopus 로고    scopus 로고
    • Meeting a mammal's psychological needs: Basic principles
    • Smithsonian Institution Press, Washington, DC, USA
    • Poole T.B. Meeting a mammal's psychological needs: Basic principles. Second Nature: Environmental Enrichment for Captive Animals 1998, 94. Smithsonian Institution Press, Washington, DC, USA.
    • (1998) Second Nature: Environmental Enrichment for Captive Animals , pp. 94
    • Poole, T.B.1
  • 54
    • 0036796626 scopus 로고    scopus 로고
    • Rats' preferences for corn versus wood-based bedding and nesting materials
    • Ras T., Van de Ven M., Patterson-Kane E.G., Nelson K. Rats' preferences for corn versus wood-based bedding and nesting materials. Laboratory Animals 2002, 36:420-425.
    • (2002) Laboratory Animals , vol.36 , pp. 420-425
    • Ras, T.1    Van de Ven, M.2    Patterson-Kane, E.G.3    Nelson, K.4
  • 58
    • 0035161089 scopus 로고    scopus 로고
    • Evaluation of individually ventilated cage systems for laboratory rodents: Occupational health aspects
    • Renstroem A., Bjoering G., Hoglund A.U. Evaluation of individually ventilated cage systems for laboratory rodents: Occupational health aspects. Laboratory Animals 2001, 35:42-50.
    • (2001) Laboratory Animals , vol.35 , pp. 42-50
    • Renstroem, A.1    Bjoering, G.2    Hoglund, A.U.3
  • 59
    • 77649241764 scopus 로고    scopus 로고
    • Systematic variation improves reproducibility of animal experiments
    • Richter H., Garner J.P., Auer C., Kunert J., Würbel H. Systematic variation improves reproducibility of animal experiments. Nature Methods 2010, 7:167-168.
    • (2010) Nature Methods , vol.7 , pp. 167-168
    • Richter, H.1    Garner, J.P.2    Auer, C.3    Kunert, J.4    Würbel, H.5
  • 60
    • 0003915885 scopus 로고
    • The Principles of Humane Experimental Technique
    • Methuen, London. Reprinted by UFAW, South Mimms, Potters Bar, Herts UK.
    • Russell, W.M.S., Burch, R.L., 1959. The Principles of Humane Experimental Technique. Methuen, London. Reprinted by UFAW, South Mimms, Potters Bar, Herts UK.
    • (1959)
    • Russell, W.M.S.1    Burch, R.L.2
  • 61
    • 84455194754 scopus 로고    scopus 로고
    • Enrichment materials do not negatively affect reproductive success and offspring survival and weight in mice
    • Shair H.N., Nunez Y., Osman M.M. Enrichment materials do not negatively affect reproductive success and offspring survival and weight in mice. Lab Animal (NY) 2011, 41:14-19.
    • (2011) Lab Animal (NY) , vol.41 , pp. 14-19
    • Shair, H.N.1    Nunez, Y.2    Osman, M.M.3
  • 62
    • 0030899470 scopus 로고    scopus 로고
    • Behavioural demand functions of caged laboratory mice for additional space
    • Sherwin C.M., Nicol C.J. Behavioural demand functions of caged laboratory mice for additional space. Animal Behaviour 1997, 53:67-74.
    • (1997) Animal Behaviour , vol.53 , pp. 67-74
    • Sherwin, C.M.1    Nicol, C.J.2
  • 63
    • 79955759392 scopus 로고    scopus 로고
    • The impact of environmental enrichment in laboratory rats-behavioural and neurochemical aspects
    • Simpson J., Kelly J.P. The impact of environmental enrichment in laboratory rats-behavioural and neurochemical aspects. Behavioral Brain Research 2011, 222:246-264.
    • (2011) Behavioral Brain Research , vol.222 , pp. 246-264
    • Simpson, J.1    Kelly, J.P.2
  • 65
    • 17144380615 scopus 로고    scopus 로고
    • Environmental enrichment for laboratory animals
    • In: Reuter, J.D., Suckow, M.A. (Eds.), Laboratory Animal Medicine and Management, International Veterinary Information Service, B2520.0404.
    • Stewart, K.L., Bayne, K., 2004. Environmental enrichment for laboratory animals. In: Reuter, J.D., Suckow, M.A. (Eds.), Laboratory Animal Medicine and Management, International Veterinary Information Service, B2520.0404.
    • (2004)
    • Stewart, K.L.1    Bayne, K.2
  • 66
    • 77955902088 scopus 로고    scopus 로고
    • An environmental enrichment model for mice
    • Sztainberg Y., Chen A. An environmental enrichment model for mice. Nature Protocols 2010, 5:1535-1539.
    • (2010) Nature Protocols , vol.5 , pp. 1535-1539
    • Sztainberg, Y.1    Chen, A.2
  • 67
    • 0142062154 scopus 로고    scopus 로고
    • Are the effects of different designs on the physiology and behaviour of DBA/2 mice consistent?
    • Tsai P.P., Stelzer H.D., Hedrich H.J., Hackbarth H. Are the effects of different designs on the physiology and behaviour of DBA/2 mice consistent?. Laboratory Animals 2003, 37:314-327.
    • (2003) Laboratory Animals , vol.37 , pp. 314-327
    • Tsai, P.P.1    Stelzer, H.D.2    Hedrich, H.J.3    Hackbarth, H.4
  • 70
    • 0142125401 scopus 로고    scopus 로고
    • Male management: Coping with aggression problems in male laboratory mice
    • Van Loo P.L.P., Van Zutphen L.F.M., Baumans V. Male management: Coping with aggression problems in male laboratory mice. Laboratory Animals 2003, 37:300-313.
    • (2003) Laboratory Animals , vol.37 , pp. 300-313
    • Van Loo, P.L.P.1    Van Zutphen, L.F.M.2    Baumans, V.3
  • 71
    • 1642504300 scopus 로고    scopus 로고
    • The importance of learning young: The use of nesting material in laboratory rats
    • Van Loo P.L.P., Baumans V. The importance of learning young: The use of nesting material in laboratory rats. Laboratory Animals 2004, 38:17-24.
    • (2004) Laboratory Animals , vol.38 , pp. 17-24
    • Van Loo, P.L.P.1    Baumans, V.2
  • 72
    • 13244289836 scopus 로고    scopus 로고
    • Assessment of the use of two commercially available environmental enrichments by laboratory mice by preference testing
    • Van Loo P.L.P., Blom H.J.M., Meijer M.K., Baumans V. Assessment of the use of two commercially available environmental enrichments by laboratory mice by preference testing. Laboratory Animals 2005, 39:58-67.
    • (2005) Laboratory Animals , vol.39 , pp. 58-67
    • Van Loo, P.L.P.1    Blom, H.J.M.2    Meijer, M.K.3    Baumans, V.4
  • 73
    • 37049009717 scopus 로고    scopus 로고
    • Impact of 'living apart together' on postoperative recovery of mice compared with social and individual housing
    • Van Loo P.L.P., Kuin N., Sommer R., Avsaroglu H., Pham T., Baumans V. Impact of 'living apart together' on postoperative recovery of mice compared with social and individual housing. Laboratory Animals 2007, 41:441-455.
    • (2007) Laboratory Animals , vol.41 , pp. 441-455
    • Van Loo, P.L.P.1    Kuin, N.2    Sommer, R.3    Avsaroglu, H.4    Pham, T.5    Baumans, V.6
  • 76
    • 17144389357 scopus 로고    scopus 로고
    • Balancing animal research with animal well-being: Establishment of goals and harmonization of approaches
    • Weed J.L., Raber J.M. Balancing animal research with animal well-being: Establishment of goals and harmonization of approaches. ILAR Journal 2005, 46:118-128.
    • (2005) ILAR Journal , vol.46 , pp. 118-128
    • Weed, J.L.1    Raber, J.M.2
  • 80
    • 0035313968 scopus 로고    scopus 로고
    • Ideal homes? Housing effects on rodent brain and behaviour
    • Würbel H. Ideal homes? Housing effects on rodent brain and behaviour. Trends in Neurosciences 2001, 24:207-211.
    • (2001) Trends in Neurosciences , vol.24 , pp. 207-211
    • Würbel, H.1
  • 81
    • 70350741654 scopus 로고    scopus 로고
    • Environmental enrichment does not disrupt standardisation of animal experiments
    • ALTEX Special Issue
    • Würbel, H., 2007. Environmental enrichment does not disrupt standardisation of animal experiments. ALTEX Special Issue, pp. 70-73.
    • (2007) , pp. 70-73
    • Würbel, H.1
  • 82
    • 70449661650 scopus 로고    scopus 로고
    • Refinement of rodent research through environmental enrichment and systematic randomization
    • refinement and reduction of animals in research: London, UK.
    • Würbel, H., Garner, J.P., 2007. Refinement of rodent research through environmental enrichment and systematic randomization. National centre for the replacement, refinement and reduction of animals in research: London, UK. http://www.Nc3rs.org.uk.
    • (2007) National centre for the replacement
    • Würbel, H.1    Garner, J.P.2


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