Hypertension-Linked Mutation of α-Adducin Increases CFTR Surface Expression and Activity in HEK and Cultured Rat Distal Convoluted Tubule Cells

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Mondini, Anna ^a   Sassone, Francesca ^a   Civello, Davide Antonio ^a   Garavaglia, Maria Lisa ^a   Bazzini, Claudia ^a   Rodighiero, Simona ^b   Vezzoli, Valeria ^a   Conti, Fabio ^c   Torielli, Lucia ^c   Capasso, Giovanbattista ^d   Paulmichl, Markus ^e   Meyer, Giuliano ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b Fondazione Filarete   (Italy)

^c Prassis Sigma Tau Research Institute   (Italy)

^d SECOND UNIVERSITY OF NAPLES   (Italy)

^e PARACELSUS MEDICAL UNIVERSITY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ADDUCIN; CYCLIC AMP; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; FORSKOLIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL STRAIN HEK293; CELL SURFACE; CHANNEL DENSITY; CHEMICAL PARAMETERS; CHLORIDE CURRENT; CONTROLLED STUDY; EMBRYO; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYPERTENSION; KIDNEY DISTAL TUBULE; KIDNEY TUBULE CELL; MALE; MOLECULAR DYNAMICS; NONHUMAN; PATCH CLAMP; PHOTOACTIVATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEIN RETENTION; RAT; UPREGULATION; WESTERN BLOTTING; WHOLE CELL;

ANIMALS; CALMODULIN-BINDING PROTEINS; CELL MEMBRANE; CELLS, CULTURED; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DISEASE MODELS, ANIMAL; GENE EXPRESSION; HEK293 CELLS; HUMANS; HYPERTENSION; KIDNEY TUBULES, DISTAL; MALE; MUTATION; PATCH-CLAMP TECHNIQUES; PROTEIN BINDING; RATS; SIGNAL TRANSDUCTION;

RATTUS; RATTUS NORVEGICUS;

EID: 84871356223     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052014     Document Type: Article

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