-
1
-
-
0025200567
-
Primary structure of Torpedo marmorata chloride channel isolated by expression cloning in Xenopus oocytes
-
Jentsch TJ, Steinmeyer K, Schwarz G (1990) Primary structure of Torpedo marmorata chloride channel isolated by expression cloning in Xenopus oocytes. Nature 348:510-514
-
(1990)
Nature
, vol.348
, pp. 510-514
-
-
Jentsch, T.J.1
Steinmeyer, K.2
Schwarz, G.3
-
2
-
-
0031022816
-
Subunit stoichiometry of human muscle chloride channels
-
Fahlke C, Knittle T, Gurnett CA, Campbell KP, George AL Jr (1997) Subunit stoichiometry of human muscle chloride channels. J Gen Physiol 109:93-104
-
(1997)
J Gen Physiol
, vol.109
, pp. 93-104
-
-
Fahlke, C.1
Knittle, T.2
Gurnett, C.A.3
Campbell, K.P.4
George Jr., A.L.5
-
3
-
-
2442568774
-
Selectively reduced expression of thick ascending limb Tamm-Horsfall protein in hypothyroid kidneys
-
Schmitt R, Kahl T, Mutig K, Bachmann S (2004) Selectively reduced expression of thick ascending limb Tamm-Horsfall protein in hypothyroid kidneys. Histochem Cell Biol 121:319-327
-
(2004)
Histochem Cell Biol
, vol.121
, pp. 319-327
-
-
Schmitt, R.1
Kahl, T.2
Mutig, K.3
Bachmann, S.4
-
4
-
-
0032921415
-
The muscle chloride channel ClC-1 has a double-barreled appearance that is differentially affected in dominant and recessive myotonia
-
Saviane C, Conti F, Pusch M (1999) The muscle chloride channel ClC-1 has a double-barreled appearance that is differentially affected in dominant and recessive myotonia. J Gen Physiol 113:457-468
-
(1999)
J Gen Physiol
, vol.113
, pp. 457-468
-
-
Saviane, C.1
Conti, F.2
Pusch, M.3
-
5
-
-
0035951822
-
Pores formed by single subunits in mixed dimers of different CLC chloride channels
-
Weinreich F, Jentsch TJ (2001) Pores formed by single subunits in mixed dimers of different CLC chloride channels. J Biol Chem 276:2347-2353
-
(2001)
J Biol Chem
, vol.276
, pp. 2347-2353
-
-
Weinreich, F.1
Jentsch, T.J.2
-
6
-
-
0036083537
-
Molecular structure and physiological function of chloride channels
-
Jentsch TJ, Stein V, Weinreich F, Zdebik AA (2002) Molecular structure and physiological function of chloride channels. Physiol Rev 82:503-568
-
(2002)
Physiol Rev
, vol.82
, pp. 503-568
-
-
Jentsch, T.J.1
Stein, V.2
Weinreich, F.3
Zdebik, A.A.4
-
7
-
-
0029743660
-
Two physically distinct pores in the dimeric ClC-0 chloride channel
-
Ludewig U, Pusch M, Jentsch TJ (1996) Two physically distinct pores in the dimeric ClC-0 chloride channel. Nature 383:340-343
-
(1996)
Nature
, vol.383
, pp. 340-343
-
-
Ludewig, U.1
Pusch, M.2
Jentsch, T.J.3
-
8
-
-
0030840713
-
Independent gating of single pores in CLC-0 chloride channels
-
Ludewig U, Pusch M, Jentsch TJ (1997) Independent gating of single pores in CLC-0 chloride channels. Biophys J 73:789-797
-
(1997)
Biophys J
, vol.73
, pp. 789-797
-
-
Ludewig, U.1
Pusch, M.2
Jentsch, T.J.3
-
9
-
-
0020440405
-
Open-state substructure of single chloride channels from Torpedo electroplax
-
Miller C (1982) Open-state substructure of single chloride channels from Torpedo electroplax. Philos Trans R Soc Lond B Biol Sci 299:401-411
-
(1982)
Philos Trans R Soc Lond B Biol Sci
, vol.299
, pp. 401-411
-
-
Miller, C.1
-
10
-
-
0037122805
-
X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity
-
Dutzler R, Campbell EB, Cadene M, Chait BT, MacKinnon R (2002) X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity. Nature 415:287-294
-
(2002)
Nature
, vol.415
, pp. 287-294
-
-
Dutzler, R.1
Campbell, E.B.2
Cadene, M.3
Chait, B.T.4
MacKinnon, R.5
-
11
-
-
0035969520
-
Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion
-
Estevez R, Boettger T, Stein V, Birkenhager R, Otto E, Hildebrandt F, Jentsch TJ (2001) Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion. Nature 414:558-561
-
(2001)
Nature
, vol.414
, pp. 558-561
-
-
Estevez, R.1
Boettger, T.2
Stein, V.3
Birkenhager, R.4
Otto, E.5
Hildebrandt, F.6
Jentsch, T.J.7
-
12
-
-
9144241252
-
Investigations of pharmacologic properties of the renal CLC-K1 chloride channel co-expressed with barttin by the use of 2-(p-Chlorophenoxy)propionic acid derivatives and other structurally unrelated chloride channels blockers
-
Liantonio A, Pusch M, Picollo A, Guida P, De Luca A, Pierno S, Fracchiolla G, Loiodice F, Tortorella P, Conte CD (2004) Investigations of pharmacologic properties of the renal CLC-K1 chloride channel co-expressed with barttin by the use of 2-(p-Chlorophenoxy)propionic acid derivatives and other structurally unrelated chloride channels blockers. J Am Soc Nephrol 15:13-20
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 13-20
-
-
Liantonio, A.1
Pusch, M.2
Picollo, A.3
Guida, P.4
De Luca, A.5
Pierno, S.6
Fracchiolla, G.7
Loiodice, F.8
Tortorella, P.9
Conte, C.D.10
-
13
-
-
0036452353
-
Barttin increases surface expression and changes current properties of ClC-K channels
-
Waldegger S, Jeck N, Barth P, Peters M, Vitzthum H, Wolf K, Kurtz A, Konrad M, Seyberth HW (2002) Barttin increases surface expression and changes current properties of ClC-K channels. Pflugers Arch 444:411-418
-
(2002)
Pflugers Arch
, vol.444
, pp. 411-418
-
-
Waldegger, S.1
Jeck, N.2
Barth, P.3
Peters, M.4
Vitzthum, H.5
Wolf, K.6
Kurtz, A.7
Konrad, M.8
Seyberth, H.W.9
-
14
-
-
0037418859
-
Gating the selectivity filter in ClC chloride channels
-
Dutzler R, Campbell EB, MacKinnon R (2003) Gating the selectivity filter in ClC chloride channels. Science 300:108-112
-
(2003)
Science
, vol.300
, pp. 108-112
-
-
Dutzler, R.1
Campbell, E.B.2
MacKinnon, R.3
-
15
-
-
0345767047
-
A conserved pore-lining glutamate as a voltage- and chloride-dependent gate in the ClC-2 chloride channel
-
Niemeyer MI, Cid LP, Zuniga L, Catalan M, Sepulveda FV (2003) A conserved pore-lining glutamate as a voltage- and chloride-dependent gate in the ClC-2 chloride channel. J Physiol 553:873-879
-
(2003)
J Physiol
, vol.553
, pp. 873-879
-
-
Niemeyer, M.I.1
Cid, L.P.2
Zuniga, L.3
Catalan, M.4
Sepulveda, F.V.5
-
16
-
-
2642687664
-
The swelling-activated chloride channel ClC-2, the chloride channel ClC-3, and ClC-5, a chloride channel mutated in kidney stone disease, are expressed in distinct subpopulations of renal epithelial cells
-
Obermuller N, Gretz N, Kriz W, Reilly RF, Witzgall R (1998) The swelling-activated chloride channel ClC-2, the chloride channel ClC-3, and ClC-5, a chloride channel mutated in kidney stone disease, are expressed in distinct subpopulations of renal epithelial cells. J Clin Invest 101:635-642
-
(1998)
J Clin Invest
, vol.101
, pp. 635-642
-
-
Obermuller, N.1
Gretz, N.2
Kriz, W.3
Reilly, R.F.4
Witzgall, R.5
-
17
-
-
0031888077
-
Characteristics of rabbit ClC-2 current expressed in Xenopus oocytes and its contribution to volume regulation
-
Furukawa T, Ogura T, Katayama Y, Hiraoka M (1998) Characteristics of rabbit ClC-2 current expressed in Xenopus oocytes and its contribution to volume regulation. Am J Physiol 274:C500-C512
-
(1998)
Am J Physiol
, vol.274
-
-
Furukawa, T.1
Ogura, T.2
Katayama, Y.3
Hiraoka, M.4
-
18
-
-
4944241868
-
Plasmodium induces swelling-activated ClC-2 anion channels in the host erythrocyte
-
Huber SM, Duranton C, Henke G, Van De SC, Heussler V, Shumilina E, Sandu CD, Tanneur V, Brand V, Kasinathan RS, Lang KS, Kremsner PG, Hubner CA, Rust MB, Dedek K, Jentsch TJ, Lang F (2004) Plasmodium induces swelling-activated ClC-2 anion channels in the host erythrocyte. J Biol Chem 279:41444-41452
-
(2004)
J Biol Chem
, vol.279
, pp. 41444-41452
-
-
Huber, S.M.1
Duranton, C.2
Henke, G.3
Van De, S.C.4
Heussler, V.5
Shumilina, E.6
Sandu, C.D.7
Tanneur, V.8
Brand, V.9
Kasinathan, R.S.10
Lang, K.S.11
Kremsner, P.G.12
Hubner, C.A.13
Rust, M.B.14
Dedek, K.15
Jentsch, T.J.16
Lang, F.17
-
19
-
-
0035868910
-
Male germ cells and photoreceptors, both dependent on close cell-cell interactions, degenerate upon ClC-2 Cl(-) channel disruption
-
Bosl MR, Stein V, Hubner C, Zdebik AA, Jordt SE, Mukhopadhyay AK, Davidoff MS, Holstein AF, Jentsch TJ (2001) Male germ cells and photoreceptors, both dependent on close cell-cell interactions, degenerate upon ClC-2 Cl(-) channel disruption. EMBO J 20:1289-1299
-
(2001)
EMBO J
, vol.20
, pp. 1289-1299
-
-
Bosl, M.R.1
Stein, V.2
Hubner, C.3
Zdebik, A.A.4
Jordt, S.E.5
Mukhopadhyay, A.K.6
Davidoff, M.S.7
Holstein, A.F.8
Jentsch, T.J.9
-
20
-
-
0035998271
-
CLC-3 deficiency leads to phenotypes similar to human neuronal ceroid lipofuscinosis
-
Yoshikawa M, Uchida S, Ezaki J, Rai T, Hayama A, Kobayashi K, Kida Y, Noda M, Koike M, Uchiyama Y, Marumo F, Kominami E, Sasaki S (2002) CLC-3 deficiency leads to phenotypes similar to human neuronal ceroid lipofuscinosis. Genes Cells 7:597-605
-
(2002)
Genes Cells
, vol.7
, pp. 597-605
-
-
Yoshikawa, M.1
Uchida, S.2
Ezaki, J.3
Rai, T.4
Hayama, A.5
Kobayashi, K.6
Kida, Y.7
Noda, M.8
Koike, M.9
Uchiyama, Y.10
Marumo, F.11
Kominami, E.12
Sasaki, S.13
-
21
-
-
0035951282
-
Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man
-
Kornak U, Kasper D, Bosl MR, Kaiser E, Schweizer M, Schulz A, Friedrich W, Delling G, Jentsch TJ (2001) Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man. Cell 104:205-215
-
(2001)
Cell
, vol.104
, pp. 205-215
-
-
Kornak, U.1
Kasper, D.2
Bosl, M.R.3
Kaiser, E.4
Schweizer, M.5
Schulz, A.6
Friedrich, W.7
Delling, G.8
Jentsch, T.J.9
-
22
-
-
0942290526
-
Inherited hypercalciuric syndromes: Dent's disease (CLC-5) and familial hypomagnesemia with hypercalciuria (paracellin-1)
-
Knohl SJ, Scheinman SJ (2004) Inherited hypercalciuric syndromes: Dent's disease (CLC-5) and familial hypomagnesemia with hypercalciuria (paracellin-1). Semin Nephrol 24:55-60
-
(2004)
Semin Nephrol
, vol.24
, pp. 55-60
-
-
Knohl, S.J.1
Scheinman, S.J.2
-
23
-
-
0037386323
-
Novel truncating mutations in the ClC-5 chloride channel gene in patients with Dent's disease
-
Carballo-Trujillo I, Garcia-Nieto V, Moya-Angeler FJ, Anton-Gamero M, Loris C, Mendez-Alvarez S, Claverie-Martin F (2003) Novel truncating mutations in the ClC-5 chloride channel gene in patients with Dent's disease. Nephrol Dial Transplant 18:717-723
-
(2003)
Nephrol Dial Transplant
, vol.18
, pp. 717-723
-
-
Carballo-Trujillo, I.1
Garcia-Nieto, V.2
Moya-Angeler, F.J.3
Anton-Gamero, M.4
Loris, C.5
Mendez-Alvarez, S.6
Claverie-Martin, F.7
-
24
-
-
0242690915
-
De novo insertion of an Alu sequence in the coding region of the CLCN5 gene results in Dent's disease
-
Claverie-Martin F, Gonzalez-Acosta H, Flores C, Anton-Gamero M, Garcia-Nieto V (2003) De novo insertion of an Alu sequence in the coding region of the CLCN5 gene results in Dent's disease. Hum Genet 113:480-485
-
(2003)
Hum Genet
, vol.113
, pp. 480-485
-
-
Claverie-Martin, F.1
Gonzalez-Acosta, H.2
Flores, C.3
Anton-Gamero, M.4
Garcia-Nieto, V.5
-
25
-
-
0032953770
-
Intra-renal and subcellular distribution of the human chloride channel, CLC-5, reveals a pathophysiological basis for Dent's disease
-
Devuyst O, Christie PT, Courtoy PJ, Beauwens R, Thakker RV (1999) Intra-renal and subcellular distribution of the human chloride channel, CLC-5, reveals a pathophysiological basis for Dent's disease. Hum Mol Genet 8:247-257
-
(1999)
Hum Mol Genet
, vol.8
, pp. 247-257
-
-
Devuyst, O.1
Christie, P.T.2
Courtoy, P.J.3
Beauwens, R.4
Thakker, R.V.5
-
26
-
-
0034676433
-
ClC-5 Cl- -channel disruption impairs endocytosis in a mouse model for Dent's disease
-
Piwon N, Gunther W, Schwake M, Bosl MR, Jentsch TJ (2000) ClC-5 Cl- -channel disruption impairs endocytosis in a mouse model for Dent's disease. Nature 408:369-373
-
(2000)
Nature
, vol.408
, pp. 369-373
-
-
Piwon, N.1
Gunther, W.2
Schwake, M.3
Bosl, M.R.4
Jentsch, T.J.5
-
27
-
-
0034642297
-
Mice lacking renal chloride channel, CLC-5, are a model for Dent's disease, a nephrolithiasis disorder associated with defective receptor-mediated endocytosis
-
Wang SS, Devuyst O, Courtoy PJ, Wang XT, Wang H, Wang Y, Thakker RV, Guggino S, Guggino WB (2000) Mice lacking renal chloride channel, CLC-5, are a model for Dent's disease, a nephrolithiasis disorder associated with defective receptor-mediated endocytosis. Hum Mol Genet 9:2937-2945
-
(2000)
Hum Mol Genet
, vol.9
, pp. 2937-2945
-
-
Wang, S.S.1
Devuyst, O.2
Courtoy, P.J.3
Wang, X.T.4
Wang, H.5
Wang, Y.6
Thakker, R.V.7
Guggino, S.8
Guggino, W.B.9
-
28
-
-
0038153196
-
Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules
-
Christensen EI, Devuyst O, Dom G, Nielsen R, Van der SP, Verroust P, Leruth M, Guggino WB, Courtoy PJ (2003) Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules. Proc Natl Acad Sci USA 100:8472-8477
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8472-8477
-
-
Christensen, E.I.1
Devuyst, O.2
Dom, G.3
Nielsen, R.4
Van der, S.P.5
Verroust, P.6
Leruth, M.7
Guggino, W.B.8
Courtoy, P.J.9
-
29
-
-
0029609597
-
Cloning and functional expression of rat CLC-5, a chloride channel related to kidney disease
-
Steinmeyer K, Schwappach B, Bens M, Vandewalle A, Jentsch TJ (1995) Cloning and functional expression of rat CLC-5, a chloride channel related to kidney disease. J Biol Chem 270:31172-31177
-
(1995)
J Biol Chem
, vol.270
, pp. 31172-31177
-
-
Steinmeyer, K.1
Schwappach, B.2
Bens, M.3
Vandewalle, A.4
Jentsch, T.J.5
-
30
-
-
0037378408
-
Altered polarity and expression of H+-ATPase without ultrastructural changes in kidneys of Dent's disease patients
-
Moulin P, Igarashi T, Van der SP, Cosyns JP, Verroust P, Thakker RV, Scheinman SJ, Courtoy PJ, Devuyst O (2003) Altered polarity and expression of H+-ATPase without ultrastructural changes in kidneys of Dent's disease patients. Kidney Int 63:1285-1295
-
(2003)
Kidney Int
, vol.63
, pp. 1285-1295
-
-
Moulin, P.1
Igarashi, T.2
Van der, S.P.3
Cosyns, J.P.4
Verroust, P.5
Thakker, R.V.6
Scheinman, S.J.7
Courtoy, P.J.8
Devuyst, O.9
-
31
-
-
32044456999
-
Disruption of clc-5 leads to a redistribution of annexin A2 and promotes calcium crystal agglomeration in collecting duct epithelial cells
-
Carr G, Simmons NL, Sayer JA (2006) Disruption of clc-5 leads to a redistribution of annexin A2 and promotes calcium crystal agglomeration in collecting duct epithelial cells. Cell Mol Life Sci 63:367-377
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 367-377
-
-
Carr, G.1
Simmons, N.L.2
Sayer, J.A.3
-
32
-
-
11244331526
-
Nedd4-2 functionally interacts with ClC-5: Involvement in constitutive albumin endocytosis in proximal tubule cells
-
Hryciw DH, Ekberg J, Lee A, Lensink IL, Kumar S, Guggino WB, Cook DI, Pollock CA, Poronnik P (2004) Nedd4-2 functionally interacts with ClC-5: involvement in constitutive albumin endocytosis in proximal tubule cells. J Biol Chem 279:54996-55007
-
(2004)
J Biol Chem
, vol.279
, pp. 54996-55007
-
-
Hryciw, D.H.1
Ekberg, J.2
Lee, A.3
Lensink, I.L.4
Kumar, S.5
Guggino, W.B.6
Cook, D.I.7
Pollock, C.A.8
Poronnik, P.9
-
33
-
-
0028292022
-
Two isoforms of a chloride channel predominantly expressed in thick ascending limb of Henle's loop and collecting ducts of rat kidney
-
Adachi S, Uchida S, Ito H, Hata M, Hiroe M, Marumo F, Sasaki S (1994) Two isoforms of a chloride channel predominantly expressed in thick ascending limb of Henle's loop and collecting ducts of rat kidney. J Biol Chem 269:17677-17683
-
(1994)
J Biol Chem
, vol.269
, pp. 17677-17683
-
-
Adachi, S.1
Uchida, S.2
Ito, H.3
Hata, M.4
Hiroe, M.5
Marumo, F.6
Sasaki, S.7
-
34
-
-
0028832124
-
Localization and functional characterization of rat kidney-specific chloride channel, ClC-K1
-
Uchida S, Sasaki S, Nitta K, Uchida K, Horita S, Nihei H, Marumo F (1995) Localization and functional characterization of rat kidney-specific chloride channel, ClC-K1. J Clin Invest 95:104-113
-
(1995)
J Clin Invest
, vol.95
, pp. 104-113
-
-
Uchida, S.1
Sasaki, S.2
Nitta, K.3
Uchida, K.4
Horita, S.5
Nihei, H.6
Marumo, F.7
-
35
-
-
0028360729
-
Two highly homologous members of the ClC chloride channel family in both rat and human kidney
-
Kieferle S, Fong P, Bens M, Vandewalle A, Jentsch TJ (1994) Two highly homologous members of the ClC chloride channel family in both rat and human kidney. Proc Natl Acad Sci USA 91:6943-6947
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 6943-6947
-
-
Kieferle, S.1
Fong, P.2
Bens, M.3
Vandewalle, A.4
Jentsch, T.J.5
-
36
-
-
0141817688
-
Parallel down-regulation of chloride channel CLC-K1 and barttin mRNA in the thin ascending limb of the rat nephron by furosemide
-
Wolf K, Meier-Meitinger M, Bergler T, Castrop H, Vitzthum H, Riegger GA, Kurtz A, Kramer BK (2003) Parallel down-regulation of chloride channel CLC-K1 and barttin mRNA in the thin ascending limb of the rat nephron by furosemide. Pflugers Arch 446:665-671
-
(2003)
Pflugers Arch
, vol.446
, pp. 665-671
-
-
Wolf, K.1
Meier-Meitinger, M.2
Bergler, T.3
Castrop, H.4
Vitzthum, H.5
Riegger, G.A.6
Kurtz, A.7
Kramer, B.K.8
-
37
-
-
0036065957
-
Human CLC-KB gene promoter drives the EGFP expression in the specific distal nephron segments and inner ear
-
Kobayashi K, Uchida S, Okamura HO, Marumo F, Sasaki S (2002) Human CLC-KB gene promoter drives the EGFP expression in the specific distal nephron segments and inner ear. J Am Soc Nephrol 13:1992-1998
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 1992-1998
-
-
Kobayashi, K.1
Uchida, S.2
Okamura, H.O.3
Marumo, F.4
Sasaki, S.5
-
38
-
-
0033811259
-
Overexpression of chloride channel CLC-K2 mRNA in the renal medulla of Dahl salt-sensitive rats
-
Castrop H, Kramer BK, Riegger GA, Kurtz A, Wolf K (2000) Overexpression of chloride channel CLC-K2 mRNA in the renal medulla of Dahl salt-sensitive rats. J Hypertens 18:1289-1295
-
(2000)
J Hypertens
, vol.18
, pp. 1289-1295
-
-
Castrop, H.1
Kramer, B.K.2
Riegger, G.A.3
Kurtz, A.4
Wolf, K.5
-
39
-
-
0036156502
-
Nephron specific regulation of chloride channel CLC-K2 mRNA in the rat
-
Vitzthum H, Castrop H, Meier-Meitinger M, Riegger GA, Kurtz A, Kramer BK, Wolf K (2002) Nephron specific regulation of chloride channel CLC-K2 mRNA in the rat. Kidney Int 61:547-554
-
(2002)
Kidney Int
, vol.61
, pp. 547-554
-
-
Vitzthum, H.1
Castrop, H.2
Meier-Meitinger, M.3
Riegger, G.A.4
Kurtz, A.5
Kramer, B.K.6
Wolf, K.7
-
40
-
-
0030851745
-
Localization and induction by dehydration of ClC-K chloride channels in the rat kidney
-
Vandewalle A, Cluzeaud F, Bens M, Kieferle S, Steinmeyer K, Jentsch TJ (1997) Localization and induction by dehydration of ClC-K chloride channels in the rat kidney. Am J Physiol 272:F678-F688
-
(1997)
Am J Physiol
, vol.272
-
-
Vandewalle, A.1
Cluzeaud, F.2
Bens, M.3
Kieferle, S.4
Steinmeyer, K.5
Jentsch, T.J.6
-
42
-
-
0033798255
-
Severely impaired urine-concentrating ability in mice lacking the CLC-K1 chloride channel
-
Uchida S, Marumo F (2000) Severely impaired urine-concentrating ability in mice lacking the CLC-K1 chloride channel. Exp Nephrol 8:361-365
-
(2000)
Exp Nephrol
, vol.8
, pp. 361-365
-
-
Uchida, S.1
Marumo, F.2
-
43
-
-
0042166134
-
Molecular mechanisms of Bartter syndrome caused by mutations in the BSND gene
-
Hayama A, Rai T, Sasaki S, Uchida S (2003) Molecular mechanisms of Bartter syndrome caused by mutations in the BSND gene. Histochem Cell Biol 119:485-493
-
(2003)
Histochem Cell Biol
, vol.119
, pp. 485-493
-
-
Hayama, A.1
Rai, T.2
Sasaki, S.3
Uchida, S.4
-
44
-
-
0033914432
-
Mutations in the chloride channel gene CLCNKB as a cause of classic Bartter syndrome
-
Konrad M, Vollmer M, Lemmink HH, van den Heuvel LP, Jeck N, Vargas-Poussou R, Lakings A, Ruf R, Deschenes G, Antignac C, Guay-Woodford L, Knoers NV, Seyberth HW, Feldmann D, Hildebrandt F (2000) Mutations in the chloride channel gene CLCNKB as a cause of classic Bartter syndrome. J Am Soc Nephrol 11:1449-1459
-
(2000)
J Am Soc Nephrol
, vol.11
, pp. 1449-1459
-
-
Konrad, M.1
Vollmer, M.2
Lemmink, H.H.3
van den Heuvel, L.P.4
Jeck, N.5
Vargas-Poussou, R.6
Lakings, A.7
Ruf, R.8
Deschenes, G.9
Antignac, C.10
Guay-Woodford, L.11
Knoers, N.V.12
Seyberth, H.W.13
Feldmann, D.14
Hildebrandt, F.15
-
45
-
-
2542446285
-
Activating mutation of the renal epithelial chloride channel ClC-Kb predisposing to hypertension
-
Jeck N, Waldegger S, Lampert A, Boehmer C, Waldegger P, Lang PA, Wissinger B, Friedrich B, Risler T, Moehle R, Lang UE, Zill P, Bondy B, Schaeffeler E, Asante-Poku S, Seyberth H, Schwab M, Lang F (2004) Activating mutation of the renal epithelial chloride channel ClC-Kb predisposing to hypertension. Hypertension 43:1175-1181
-
(2004)
Hypertension
, vol.43
, pp. 1175-1181
-
-
Jeck, N.1
Waldegger, S.2
Lampert, A.3
Boehmer, C.4
Waldegger, P.5
Lang, P.A.6
Wissinger, B.7
Friedrich, B.8
Risler, T.9
Moehle, R.10
Lang, U.E.11
Zill, P.12
Bondy, B.13
Schaeffeler, E.14
Asante-Poku, S.15
Seyberth, H.16
Schwab, M.17
Lang, F.18
-
46
-
-
0347362500
-
A common sequence variation of the CLCNKB gene strongly activates ClC-Kb chloride channel activity
-
Jeck N, Waldegger P, Doroszewicz J, Seyberth H, Waldegger S (2004) A common sequence variation of the CLCNKB gene strongly activates ClC-Kb chloride channel activity. Kidney Int 65:190-197
-
(2004)
Kidney Int
, vol.65
, pp. 190-197
-
-
Jeck, N.1
Waldegger, P.2
Doroszewicz, J.3
Seyberth, H.4
Waldegger, S.5
-
47
-
-
0035203716
-
The cystic fibrosis transmembrane conductance regulator (CFTR) inhibits ENaC through an increase in the intracellular Cl- concentration
-
Konig J, Schreiber R, Voelcker T, Mall M, Kunzelmann K (2001) The cystic fibrosis transmembrane conductance regulator (CFTR) inhibits ENaC through an increase in the intracellular Cl- concentration. EMBO Rep 2:1047-1051
-
(2001)
EMBO Rep
, vol.2
, pp. 1047-1051
-
-
Konig, J.1
Schreiber, R.2
Voelcker, T.3
Mall, M.4
Kunzelmann, K.5
-
48
-
-
0037279932
-
ENaC is inhibited by an increase in the intracellular Cl(-) concentration mediated through activation of Cl(-) channels
-
Kunzelmann K (2003) ENaC is inhibited by an increase in the intracellular Cl(-) concentration mediated through activation of Cl(-) channels. Pflugers Arch 445:504-512
-
(2003)
Pflugers Arch
, vol.445
, pp. 504-512
-
-
Kunzelmann, K.1
-
49
-
-
0037067771
-
Cystic fibrosis transmembrane conductance regulator-dependent up-regulation of Kir1.1 (ROMK) renal K+ channels by the epithelial sodium channel
-
Konstas AA, Koch JP, Tucker SJ, Korbmacher C (2002) Cystic fibrosis transmembrane conductance regulator-dependent up-regulation of Kir1.1 (ROMK) renal K+ channels by the epithelial sodium channel. J Biol Chem 277:25377-25384
-
(2002)
J Biol Chem
, vol.277
, pp. 25377-25384
-
-
Konstas, A.A.1
Koch, J.P.2
Tucker, S.J.3
Korbmacher, C.4
-
50
-
-
4344588934
-
Cyclic AMP promotes growth and secretion in human polycystic kidney epithelial cells
-
Belibi FA, Reif G, Wallace DP, Yamaguchi T, Olsen L, Li H, Helmkamp GM Jr, Grantham JJ (2004) Cyclic AMP promotes growth and secretion in human polycystic kidney epithelial cells. Kidney Int 66:964-973
-
(2004)
Kidney Int
, vol.66
, pp. 964-973
-
-
Belibi, F.A.1
Reif, G.2
Wallace, D.P.3
Yamaguchi, T.4
Olsen, L.5
Li, H.6
Helmkamp Jr., G.M.7
Grantham, J.J.8
-
51
-
-
0031741078
-
PKD and CF: An interesting family provides insight into the molecular pathophysiology of polycystic kidney disease
-
Cotton CU, Avner ED (1998) PKD and CF: An interesting family provides insight into the molecular pathophysiology of polycystic kidney disease. Am J Kidney Dis 32:1081-1083
-
(1998)
Am J Kidney Dis
, vol.32
, pp. 1081-1083
-
-
Cotton, C.U.1
Avner, E.D.2
-
52
-
-
0035079421
-
Role of CFTR in autosomal recessive polycystic kidney disease
-
Nakanishi K, Sweeney WE, Jr., Macrae DK, Cotton CU, Avner ED (2001) Role of CFTR in autosomal recessive polycystic kidney disease. J Am Soc Nephrol 12:719-725
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 719-725
-
-
Nakanishi, K.1
Sweeney Jr., W.E.2
Macrae, D.K.3
Cotton, C.U.4
Avner, E.D.5
-
54
-
-
0035827526
-
Regulation of human CLC-3 channels by multifunctional Ca2+/ calmodulin-dependent protein kinase
-
Huang P, Liu J, Di A, Robinson NC, Musch MW, Kaetzel MA, Nelson DJ (2001) Regulation of human CLC-3 channels by multifunctional Ca2+/ calmodulin-dependent protein kinase. J Biol Chem 276:20093-20100
-
(2001)
J Biol Chem
, vol.276
, pp. 20093-20100
-
-
Huang, P.1
Liu, J.2
Di, A.3
Robinson, N.C.4
Musch, M.W.5
Kaetzel, M.A.6
Nelson, D.J.7
-
55
-
-
0031709885
-
Mutations in a novel gene, VMD2, encoding a protein of unknown properties cause juvenile-onset vitelliform macular dystrophy (Best's disease)
-
Marquardt A, Stohr H, Passmore LA, Kramer F, Rivera A, Weber BH (1998) Mutations in a novel gene, VMD2, encoding a protein of unknown properties cause juvenile-onset vitelliform macular dystrophy (Best's disease). Hum Mol Genet 7:1517-1525
-
(1998)
Hum Mol Genet
, vol.7
, pp. 1517-1525
-
-
Marquardt, A.1
Stohr, H.2
Passmore, L.A.3
Kramer, F.4
Rivera, A.5
Weber, B.H.6
-
56
-
-
0842345301
-
Two bestrophins cloned from Xenopus laevis oocytes express Ca(2+)-activated Cl(-) currents
-
Qu Z, Wei RW, Mann W, Hartzell HC (2003) Two bestrophins cloned from Xenopus laevis oocytes express Ca(2+)-activated Cl(-) currents. J Biol Chem 278:49563-49572
-
(2003)
J Biol Chem
, vol.278
, pp. 49563-49572
-
-
Qu, Z.1
Wei, R.W.2
Mann, W.3
Hartzell, H.C.4
-
57
-
-
0037133670
-
The vitelliform macular dystrophy protein defines a new family of chloride channels
-
Sun H, Tsunenari T, Yau KW, Nathans J (2002) The vitelliform macular dystrophy protein defines a new family of chloride channels. Proc Natl Acad Sci USA 99:4008-4013
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 4008-4013
-
-
Sun, H.1
Tsunenari, T.2
Yau, K.W.3
Nathans, J.4
-
58
-
-
0037497058
-
Chloride currents in acutely isolated Xenopus retinal pigment epithelial cells
-
Hartzell HC, Qu Z (2003) Chloride currents in acutely isolated Xenopus retinal pigment epithelial cells. J Physiol 549:453-469
-
(2003)
J Physiol
, vol.549
, pp. 453-469
-
-
Hartzell, H.C.1
Qu, Z.2
-
59
-
-
0142071743
-
Structure-function analysis of the bestrophin family of anion channels
-
Tsunenari T, Sun H, Williams J, Cahill H, Smallwood P, Yau KW, Nathans J (2003) Structure-function analysis of the bestrophin family of anion channels. J Biol Chem 278:41114-41125
-
(2003)
J Biol Chem
, vol.278
, pp. 41114-41125
-
-
Tsunenari, T.1
Sun, H.2
Williams, J.3
Cahill, H.4
Smallwood, P.5
Yau, K.W.6
Nathans, J.7
-
60
-
-
33744470320
-
Ca2+-activated Cl- current from human bestrophin-4 in excised membrane patches
-
Tsunenari T, Nathans J, Yau KW (2006) Ca2+-activated Cl- current from human bestrophin-4 in excised membrane patches. J Gen Physiol 127:749-754
-
(2006)
J Gen Physiol
, vol.127
, pp. 749-754
-
-
Tsunenari, T.1
Nathans, J.2
Yau, K.W.3
-
61
-
-
8844258805
-
The role of bestrophin in airway epithelial ion transport
-
Duta V, Szkotak AJ, Nahirney D, Duszyk M (2004) The role of bestrophin in airway epithelial ion transport. FEBS Lett 577:551-554
-
(2004)
FEBS Lett
, vol.577
, pp. 551-554
-
-
Duta, V.1
Szkotak, A.J.2
Nahirney, D.3
Duszyk, M.4
-
62
-
-
2542495760
-
A novel Cl channel related to Drosophila flightless locus
-
Suzuki M, Mizuno A (2004) A novel Cl channel related to Drosophila flightless locus. J Biol Chem 279:22461-22468
-
(2004)
J Biol Chem
, vol.279
, pp. 22461-22468
-
-
Suzuki, M.1
Mizuno, A.2
-
63
-
-
0032895194
-
A novel p64-related Cl-channel: Subcellular distribution and nephron segment-specific expression
-
Edwards JC (1999) A novel p64-related Cl-channel: Subcellular distribution and nephron segment-specific expression. Am J Physiol 276:F398-F408
-
(1999)
Am J Physiol
, vol.276
-
-
Edwards, J.C.1
|