Magnolol inhibits lipopolysaccharide-induced inflammatory response by interfering with TLR4 mediated NF-κB and MAPKs signaling pathways

Journal of Ethnopharmacology

Volumn 145, Issue 1, 2013, Pages 193-199

  Fu, Yunhe ^a   Liu, Bo ^a   Zhang, Naisheng ^a   Liu, Zhicheng ^a   Liang, Dejie ^a   Li, Fengyang ^a   Cao, Yongguo ^a   Feng, Xiaosheng ^b   Zhang, Xichen ^a   Yang, Zhengtao ^a  

^a JILIN UNIVERSITY   (China)

^b Guangdong Institute of Modern Agricultural Group   (China)

Author keywords

Cytokine; Magnolol; MAPK; NF B; TLR4

Indexed keywords

I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MAGNOLOL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 4;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; DRUG MECHANISM; DRUG STRUCTURE; ENZYME DEGRADATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFLAMMATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BIPHENYL COMPOUNDS; CELL SURVIVAL; CELLS, CULTURED; CYTOKINES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; INFLAMMATION; INTERLEUKIN-8; LIGNANS; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MICE; NF-KAPPA B; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TRANSFECTION;

MAGNOLIA OFFICINALIS;

EID: 84871290824     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.10.051     Document Type: Article

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