The cytosolic GH loop regulates the phosphatidylinositol 4,5-bisphosphate-induced gating kinetics of Kir2 channels

Journal of Biological Chemistry

Volumn 287, Issue 50, 2012, Pages 42278-42287

  An, Hai Long ^a,b   Lü, Shou Qin ^d   Li, Jun Wei ^b   Meng, Xuan Yu ^a   Zhan, Yong ^b   Cui, Meng ^a   Long, Mian ^d   Zhang, Hai Lin ^c   Logothetis, Diomedes E ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b HEBEI UNIVERSITY OF TECHNOLOGY   (China)

^c HEBEI MEDICAL UNIVERSITY   (China)

^d INSTITUTE OF MECHANICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSOLIC; ELECTROPHYSIOLOGICAL APPROACH; KIR CHANNEL GATING; MEMBRANE POTENTIALS; MOLECULAR MECHANISM; PHOSPHATIDYLINOSITOL 4; STRUCTURAL ELEMENTS;

ELECTROPHYSIOLOGY; PHOSPHOLIPIDS;

KINETICS;

GLYCINE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.1; LEUCINE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; VALINE;

ARTICLE; CHANNEL GATING; CONTROLLED STUDY; CYTOSOL; MEMBRANE DEPOLARIZATION; MUTATION; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

ANIMALS; ION CHANNEL GATING; KINETICS; MOLECULAR DYNAMICS SIMULATION; MUTATION, MISSENSE; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 84871261368     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.418640     Document Type: Article

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