Solvent effects on squid sodium channels are attributable to movements of a flexible protein structure in gating currents and to hydration in a pore

Journal of Physiology

Volumn 522, Issue 3, 2000, Pages 357-373

  Kukita, Fumio ^a  

^a NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHRITOL; GLUCOSE; GLYCEROL; SODIUM CHANNEL; SOLVENT; SUCROSE; ELECTROLYTE;

ANIMAL TISSUE; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; HYDRATION; HYDROPHILICITY; MOLECULAR WEIGHT; NONHUMAN; OSMOLARITY; PRIORITY JOURNAL; PROTEIN STRUCTURE; SODIUM CURRENT; SQUID; VISCOSITY; ELECTRIC POTENTIAL; KINETICS; MEMBRANE POTENTIAL; PROTEIN FUNCTION; SENSITIVITY AND SPECIFICITY; SENSOR; SOLVENT EFFECT;

EID: 0034141990     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.2000.00357.x     Document Type: Article

References (28)

1. ALDRICH, R. W. & STEVENS, C. F. (1987). Voltage-dependent gating of single sodium channels from mammalian neuroblastoma cells. Journal of Neuroscience 7, 418-431.
2. ALICATA, D. A., RAYNER, M. D. & STARKUS, J. G. (1990). Sodium channel activation mechanisms: insights from deuterium oxide substitution. Biophysical Journal 57, 745-758.
3. ARMSTRONG, C. M. & GILLY, W. F. (1979). Fast and slow steps in the activation of sodium channels. Journal of General Physiology 74, 691-711.
4. ARMSTRONG, C. M. & HILLE, B. (1998). Voltage-gated ion channels and electrical excitability. Neuron 20, 371-380.
5. ARMSTRONG, C. M. & MATTESON, D. R. (1984). Sequential models of sodium channel gating. In Current Topics in Membranes and Transport, vol. 22, The Squid Axon, ed. BAKER, P. F., pp. 331-352. Academic Press, London.
6. BÉNITAH, J.-P., RANJAN, R., YAMAGISHI, T., JANECKI, M., TOMASELLI, G. F. & MARBAN, E. (1997). Molecular motions within the pore of voltage-dependent sodium channels. Biophysical Journal 73, 603-613.
7. CONTI, F., INOUE, I., KUKITA, F. & STÜHMER, W. (1984). Pressure dependence of sodium gating currents in the squid giant axon. European Biophysics Journal 11, 137-147.
8. + conductance and selectivity. Science 280, 69-77.
9. GAVISH, B. (1986). Molecular dynamics and transient strain model of enzyme catalysis. In The Fluctuating Enzyme, ed. WELCH, G. R., pp. 263-339. John Wiley & Sons Inc. New York, USA.
10. GUTFREUND, H. (1995). Kinetics for the Life Sciences. Receptors, Transmitters and Catalysts. Cambridge University Press, Cambridge.
11. HODGKIN, A. L. & HUXLEY, A. F. (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve. Journal of Physiology 117, 500-544.
12. KARPLUS, M. & PETSKO, G. A. (1990). Molecular dynamics simulations in biology. Nature 347, 631-639.
13. KRAMERS, H. A. (1940). Brownian motion in a field of force and the diffusion model of chemical reactions. Physica (Urecht) 7, 284-304.
14. KREUSCH, A., PFAFFINGER, P. J., STEVENS, C. F. & CHOE, S. (1998). Crystal structure of the tetramerization domain of the Shaker potassium channel. Nature 392, 945-948.
15. KUKITA, F. (1982). Properties of sodium and potassium channels of the squid giant axon far below 0 °C. Journal of Membrane Biology 68, 151-160.
16. KUKITA, F. (1997). Solvent-dependent rate-limiting steps in the conformational change of sodium channel gating in a squid giant axons. Journal of Physiology 498, 109-133. (Erratum: Journal of Physiology 499, 849).
17. KUKITA, F. (1998). Data acquisition and analysis using NEC PC9800 personal computer and Autonics 204 digitizer in electrophysiological experiments. Journal of the Physiological Society of Japan 60, 171-186 (Japanese).
18. KUKITA, F. & MITAKU, S. (1993). Kinetic analysis of the denaturation process by alcohols of sodium channels in squid giant axon. Journal of Physiology 463, 523-543.
19. KUKITA, F. & YAMAGISHI, S. (1976). Prolongation of the action potential of squid giant axons in viscous solutions. Proceedings of Japan Academy 52, 323-326.
20. KUKITA, F. & YAMAGISHI, S. (1979). Slowing of the time course of the excitation of squid giant axons in viscous solutions. Journal of Membrane Biology 47, 303-325.
21. NODA, M., IKEDA, T., KAYANO, T., SUZUKI, H., TAKESHIMA, H., KURASAKI, M., TAKAHASHI, H. & NUMA, S. (1986). Existence of distinct sodium channel messenger RNAs in rat brain. Nature 320, 188-192.
22. RAYNER, M. D., STARKUS, J. G., RUBEN, P. C. & ALICATA, D. A. (1992). Voltage-sensitive and solvent-sensitive process in ion channel gating. Kinetic effects of hyperosmolar media on activation and deactivation of sodium channels. Biophysical Journal 61, 96-108.
23. STARKUS, J. G., SCHLIEF, T., RAYNER, M. D. & HEINEMANN, S. H. (1995). Unilateral exposure of Shaker B potassium channels to hyperosmolar solutions. Biophysical Journal 69, 860-872.
24. + channel pores revealed by single-and double-cysteine replacements. Journal of General Physiology 110, 59-72.
25. YANO, N., GEORGE, A. L. JR & HORN, R. (1996). Molecular basis of charge movement in voltage-gated sodium channels. Neuron 16, 113-122.
26. ZAKIM, D., KAVECANSKY, J. & SCARLATA, S. (1992). Are membrane enzymes regulated by the viscosity of the membrane environment? Biochemistry 31, 11589-11594.
27. ZAVOICO, G. B. & KUTCHAI, H. (1980). Effects of n-alkanols on the membrane fluidity of chick embryo heart microsomes. Biochimica et Biophysica Acta 600, 263-269.
28. ZIMMERBERG, J. & PARSEGIAN, V. A. (1986). Polymer inaccessible volume changes during opening and closing of a voltage-dependent ionic channel. Nature 323, 36-39.