-
1
-
-
0014348401
-
The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase
-
Tenhunen R, Marver HS, Schmid R. The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc Natl Acad Sci USA 1968; 61: 748-55.
-
(1968)
Proc Natl Acad Sci USA
, vol.61
, pp. 748-755
-
-
Tenhunen, R.1
Marver, H.S.2
Schmid, R.3
-
2
-
-
0030923630
-
The heme oxygenase system: A regulator of second messenger gases
-
Maines MD. The heme oxygenase system: a regulator of second messenger gases. Annu Rev Pharmacol Toxicol 1997; 37: 517-54.
-
(1997)
Annu Rev Pharmacol Toxicol
, vol.37
, pp. 517-554
-
-
Maines, M.D.1
-
3
-
-
33645945014
-
Heme oxygenase-1/carbon monoxide: From basic science to therapeutic applications
-
Ryter SW, Alam J, Choi AM. Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications. Physiol Rev 2006; 86: 583-650.
-
(2006)
Physiol Rev
, vol.86
, pp. 583-650
-
-
Ryter, S.W.1
Alam, J.2
Choi, A.M.3
-
4
-
-
61549122310
-
Pleiotropic functions of biliverdin reductase: Cellular signaling and generation of cytoprotective and cytotoxic bilirubin
-
Kapitulnik J, Maines MD. Pleiotropic functions of biliverdin reductase: cellular signaling and generation of cytoprotective and cytotoxic bilirubin. Trends Pharmacol Sci 2009; 30: 129-37.
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 129-137
-
-
Kapitulnik, J.1
Maines, M.D.2
-
5
-
-
0022977615
-
Purification and characterization of the major constitutive form of testicular heme oxygenase. The noninducible isoform
-
Trakshel GM, Kutty RK, Maines MD. Purification and characterization of the major constitutive form of testicular heme oxygenase. The noninducible isoform. J Biol Chem 1986 25; 261: 11131-7.
-
(1986)
J Biol Chem
, vol.25
, Issue.261
, pp. 11131-11137
-
-
Trakshel, G.M.1
Kutty, R.K.2
Maines, M.D.3
-
6
-
-
0030188587
-
Heme oxygenase-1: Function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury
-
Choi AMK, Alam J. Heme oxygenase-1: Function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury. Am J Respir Cell Mol Biol 1996; 15: 9-19.
-
(1996)
Am J Respir Cell Mol Biol
, vol.15
, pp. 9-19
-
-
Choi, A.M.K.1
Alam, J.2
-
7
-
-
0034668216
-
Gene regulation of heme oxygenase-1 as a therapeutic target
-
Immenschuh S, Ramadori G. Gene regulation of heme oxygenase-1 as a therapeutic target. Biochem Pharmacol 2000; 60: 1121-8.
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 1121-1128
-
-
Immenschuh, S.1
Ramadori, G.2
-
8
-
-
0025105624
-
Oxidant stress leads to transcriptional activation of the human heme oxygenase gene in cultured skin fibroblasts
-
Keyse SM, Applegate LA, Tromvoukis Y, Tyrrell RM. Oxidant stress leads to transcriptional activation of the human heme oxygenase gene in cultured skin fibroblasts. Mol Cell Biol 1990; 10: 4967-9.
-
(1990)
Mol Cell Biol
, vol.10
, pp. 4967-4969
-
-
Keyse, S.M.1
Applegate, L.A.2
Tromvoukis, Y.3
Tyrrell, R.M.4
-
9
-
-
0028300334
-
Heme oxygenase 1 mediates an adaptive response to oxidative stress in human skin fibroblasts
-
Vile GF, Basu-Modak S, Waltner C, Tyrrell RM. Heme oxygenase 1 mediates an adaptive response to oxidative stress in human skin fibroblasts. Proc Natl Acad Sci USA 1994 29; 91: 2607-10.
-
(1994)
Proc Natl Acad Sci USA
, vol.29
, Issue.91
, pp. 2607-2610
-
-
Vile, G.F.1
Basu-Modak, S.2
Waltner, C.3
Tyrrell, R.M.4
-
12
-
-
0030886054
-
Reduced stress defense in heme oxygenase 1-deficient cells
-
Poss KD, Tonegawa S. Reduced stress defense in heme oxygenase 1-deficient cells. Proc Natl Acad Sci USA 1997; 94: 10925-30.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 10925-10930
-
-
Poss, K.D.1
Tonegawa, S.2
-
13
-
-
0030886381
-
Heme oxygenase is required for mammalian iron reutilization
-
Poss KD, Tonegawa S. Heme oxygenase is required for mammalian iron reutilization. Proc Natl Acad Sci USA 1997; 94: 10919-24.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 10919-10924
-
-
Poss, K.D.1
Tonegawa, S.2
-
14
-
-
0032893958
-
Oxidative stress causes enhanced endothelial cell injury in human heme oxygenasedeficiency
-
Yachie A, Niida Y, Wada T, et al. Oxidative stress causes enhanced endothelial cell injury in human heme oxygenasedeficiency. J Clin Invest 1999; 103: 129-35.
-
(1999)
J Clin Invest
, vol.103
, pp. 129-135
-
-
Yachie, A.1
Niida, Y.2
Wada, T.3
-
15
-
-
0036151729
-
Heme oxygenase-1 deficiency: The first autopsy case
-
Kawashima A, Oda Y, Yachie A, Koizumi S, Nakanishi I. Heme oxygenase-1 deficiency: the first autopsy case. Hum Pathol 2002; 33: 125-30.
-
(2002)
Hum Pathol
, vol.33
, pp. 125-130
-
-
Kawashima, A.1
Oda, Y.2
Yachie, A.3
Koizumi, S.4
Nakanishi, I.5
-
16
-
-
0031913770
-
Ejaculatory abnormalities in mice with targeted disruption of the gene for heme oxygenase-2
-
Burnett AL, Johns DG, Kriegsfeld LJ, et al. Ejaculatory abnormalities in mice with targeted disruption of the gene for heme oxygenase-2. Nat Med 1998; 4: 84-7.
-
(1998)
Nat Med
, vol.4
, pp. 84-87
-
-
Burnett, A.L.1
Johns, D.G.2
Kriegsfeld, L.J.3
-
17
-
-
2042546096
-
Balancing acts: Molecular control of mammalian iron metabolism
-
Hentze MW, Muckenthaler MU, Andrews NC. Balancing acts: molecular control of mammalian iron metabolism. Cell 2004 30; 117: 285-97.
-
(2004)
Cell
, vol.30
, Issue.117
, pp. 285-297
-
-
Hentze, M.W.1
Muckenthaler, M.U.2
Andrews, N.C.3
-
19
-
-
0022368621
-
Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis
-
Niederau C, Fischer R, Sonnenberg A, Stremmel W, Trampisch HJ, Strohmeyer G. Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis. N Engl J Med 1985; 313: 1256-62.
-
(1985)
N Engl J Med
, vol.313
, pp. 1256-1262
-
-
Niederau, C.1
Fischer, R.2
Sonnenberg, A.3
Stremmel, W.4
Trampisch, H.J.5
Strohmeyer, G.6
-
20
-
-
0033599057
-
Disorders of iron metabolism
-
Andrews NC. Disorders of iron metabolism. N Engl J Med 1999; 341:1986-95.
-
(1999)
N Engl J Med
, vol.341
, pp. 1986-1995
-
-
Andrews, N.C.1
-
21
-
-
0025230751
-
The mRNA-binding protein which controls ferritin and transferrin receptor expression is conserved during evolution
-
Rothenberger S, Mullner EW, Kuhn LC. The mRNA-binding protein which controls ferritin and transferrin receptor expression is conserved during evolution. Nucleic Acids Res 1990; 18: 1175-9.
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 1175-1179
-
-
Rothenberger, S.1
Mullner, E.W.2
Kuhn, L.C.3
-
22
-
-
0030868605
-
Iron-sulfur clusters: Nature's modular, multipurpose structures
-
Beinert H, Holm RH, Munck E. Iron-sulfur clusters: nature's modular, multipurpose structures. Science 1997; 277: 653-9.
-
(1997)
Science
, vol.277
, pp. 653-659
-
-
Beinert, H.1
Holm, R.H.2
Munck, E.3
-
23
-
-
0030624029
-
Regulation of iron metabolism in eukaryotes
-
Rouault T, Klausner R. Regulation of iron metabolism in eukaryotes. Curr Top Cell Regul 1997; 35: 1-19.
-
(1997)
Curr Top Cell Regul
, vol.35
, pp. 1-19
-
-
Rouault, T.1
Klausner, R.2
-
24
-
-
0347988153
-
Blotting analysis of native IRP1: A novel approach to distinguish the different forms of IRP1 in cells and tissues
-
Campanella A, Levi S, Cairo G, Biasiotto G, Arosio P. Blotting analysis of native IRP1: a novel approach to distinguish the different forms of IRP1 in cells and tissues. Biochemistry 2004; 43: 195-204.
-
(2004)
Biochemistry
, vol.43
, pp. 195-204
-
-
Campanella, A.1
Levi, S.2
Cairo, G.3
Biasiotto, G.4
Arosio, P.5
-
25
-
-
0034717027
-
The aconitase function of iron regulatory protein 1. Genetic studies in yeast implicate its role in iron-mediated redox regulation
-
Narahari J, Ma R, Wang M, Walden WE. The aconitase function of iron regulatory protein 1. Genetic studies in yeast implicate its role in iron-mediated redox regulation. J Biol Chem 2000 26; 275: 16227-34.
-
(2000)
J Biol Chem
, vol.26
, Issue.275
, pp. 16227-16234
-
-
Narahari, J.1
Ma, R.2
Wang, M.3
Walden, W.E.4
-
26
-
-
0036358643
-
Activation of iron regulatory protein-1 (IRP1) by oxidative stress
-
Mueller S, Pantopoulos K. Activation of iron regulatory protein-1 (IRP1) by oxidative stress. Methods Enzymol 2002; 348: 324-37.
-
(2002)
Methods Enzymol
, vol.348
, pp. 324-337
-
-
Mueller, S.1
Pantopoulos, K.2
-
27
-
-
1842608845
-
Iron metabolism and the IRE/IRP regulatory system: An update
-
Pantopoulos K. Iron metabolism and the IRE/IRP regulatory system: an update. Ann N Y Acad Sci 2004; 1012: 1-13.
-
(2004)
Ann N Y Acad Sci
, vol.1012
, pp. 1-13
-
-
Pantopoulos, K.1
-
28
-
-
0035933846
-
IRP1 activation by extracellular oxidative stress in the perfused rat liver
-
Mueller S, Pantopoulos K, Hübner CA, Stremmel W, Hentze MW. IRP1 activation by extracellular oxidative stress in the perfused rat liver. J Biol Chem 2001; 276: 23192-6.
-
(2001)
J Biol Chem
, vol.276
, pp. 23192-23196
-
-
Mueller, S.1
Pantopoulos, K.2
Hübner, C.A.3
Stremmel, W.4
Hentze, M.W.5
-
29
-
-
0030942257
-
Differences in the regulation of IRP-1 (iron regulatory protein-1) by extra-and intracelullar oxidative stress
-
Pantopoulos K, Mueller S, Atzberger A, Ansorge W, Stremmel W, Hentze MW. Differences in the regulation of IRP-1 (iron regulatory protein-1) by extra-and intracelullar oxidative stress. J Biol Chem 1997; 272: 9802-8.
-
(1997)
J Biol Chem
, vol.272
, pp. 9802-9808
-
-
Pantopoulos, K.1
Mueller, S.2
Atzberger, A.3
Ansorge, W.4
Stremmel, W.5
Hentze, M.W.6
-
30
-
-
17144445166
-
Myeloperoxidase-derived hypochlorous acid antagonizes the oxidative stress-mediated activation of iron regulatory protein 1
-
Mütze S, Hebling U, Stremmel W, et al. Myeloperoxidase-derived hypochlorous acid antagonizes the oxidative stress-mediated activation of iron regulatory protein 1. J Biol Chem 2003; 278: 40542-9.
-
(2003)
J Biol Chem
, vol.278
, pp. 40542-40549
-
-
Mütze, S.1
Hebling, U.2
Stremmel, W.3
-
31
-
-
0029972895
-
Nitric oxide and oxidative stress (H2O2) control mammalian iron metabolism by different pathways
-
Pantopoulos K, Weiss G, Hentze MW. Nitric oxide and oxidative stress (H2O2) control mammalian iron metabolism by different pathways. Mol Cell Biol 1996; 16: 3781-8.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 3781-3788
-
-
Pantopoulos, K.1
Weiss, G.2
Hentze, M.W.3
-
32
-
-
2342510407
-
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
-
Nemeth E, Rivera S, Gabayan V, et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest 2004; 113: 1271-6.
-
(2004)
J Clin Invest
, vol.113
, pp. 1271-1276
-
-
Nemeth, E.1
Rivera, S.2
Gabayan, V.3
-
33
-
-
13444252281
-
Iron release from macrophages after erythrophagocytosis is upregulated by ferroportin 1 overexpression and down-regulated by hepcidin
-
Knutson MD, Oukka M, Koss LM, Aydemir F, Wessling-Resnick M. Iron release from macrophages after erythrophagocytosis is upregulated by ferroportin 1 overexpression and down-regulated by hepcidin. Proc Natl Acad Sci USA 2005; 102: 1324-8.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 1324-1328
-
-
Knutson, M.D.1
Oukka, M.2
Koss, L.M.3
Aydemir, F.4
Wessling-Resnick, M.5
-
34
-
-
33750133047
-
Regulation of iron metabolism by hepcidin
-
Nemeth E, Ganz T. Regulation of iron metabolism by hepcidin. Annu Rev Nutr 2006; 26: 323-42.
-
(2006)
Annu Rev Nutr
, vol.26
, pp. 323-342
-
-
Nemeth, E.1
Ganz, T.2
-
35
-
-
0035896581
-
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
-
Pigeon C, Ilyin G, Courselaud B, et al. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem 2001; 276: 7811-9.
-
(2001)
J Biol Chem
, vol.276
, pp. 7811-7819
-
-
Pigeon, C.1
Ilyin, G.2
Courselaud, B.3
-
36
-
-
14744278436
-
Anemia of chronic disease
-
Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med 2005; 352: 1011-23.
-
(2005)
N Engl J Med
, vol.352
, pp. 1011-1023
-
-
Weiss, G.1
Goodnough, L.T.2
-
37
-
-
0036791486
-
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
-
Nicolas G, Chauvet C, Viatte L, et al. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest 2002; 110: 1037-44.
-
(2002)
J Clin Invest
, vol.110
, pp. 1037-1044
-
-
Nicolas, G.1
Chauvet, C.2
Viatte, L.3
-
38
-
-
0037564038
-
Expression of hepcidin in hereditary hemochromatosis: Evidence for a regulation in response to the serum transferrin saturation and to non-transferrinbound iron
-
Gehrke SG, Kulaksiz H, Herrmann T, et al. Expression of hepcidin in hereditary hemochromatosis: evidence for a regulation in response to the serum transferrin saturation and to non-transferrinbound iron. Blood 2003; 102: 371-6.
-
(2003)
Blood
, vol.102
, pp. 371-376
-
-
Gehrke, S.G.1
Kulaksiz, H.2
Herrmann, T.3
-
39
-
-
0037460697
-
Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis
-
Bridle KR, Frazer DM, Wilkins SJ, et al. Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis. Lancet 2003; 361: 669-73.
-
(2003)
Lancet
, vol.361
, pp. 669-673
-
-
Bridle, K.R.1
Frazer, D.M.2
Wilkins, S.J.3
-
40
-
-
77449083073
-
Hepcidin suppression and defective iron recycling account for dysregulation of iron homeostasis in heme oxygenase-1 deficiency
-
Kartikasari AE, Wagener FA, Yachie A, Wiegerinck ET, Kemna EH, Winkels DW. Hepcidin suppression and defective iron recycling account for dysregulation of iron homeostasis in heme oxygenase-1 deficiency. J Cell Mol Med 2009; 13: 3091-102.
-
(2009)
J Cell Mol Med
, vol.13
, pp. 3091-3102
-
-
Kartikasari, A.E.1
Wagener, F.A.2
Yachie, A.3
Wiegerinck, E.T.4
Kemna, E.H.5
Winkels, D.W.6
-
41
-
-
0041672570
-
Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation
-
Ganz T. Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation. Blood 2003; 102: 783-8.
-
(2003)
Blood
, vol.102
, pp. 783-788
-
-
Ganz, T.1
-
42
-
-
33744517652
-
Iron, HCV, and liver cancer: Hard metal setting the pace?
-
Mueller S, Afdhal NH, Schuppan D. Iron, HCV, and liver cancer: hard metal setting the pace? Gastroenterology 2006; 130: 2229-34.
-
(2006)
Gastroenterology
, vol.130
, pp. 2229-2234
-
-
Mueller, S.1
Afdhal, N.H.2
Schuppan, D.3
-
43
-
-
0029834842
-
Iron overload in patients with chronic hepatitis C: A clinicopathologic study
-
Haque S, Chandra B, Gerber MA, Lok AS. Iron overload in patients with chronic hepatitis C: a clinicopathologic study. Hum Pathol 1996; 27: 1277-81.
-
(1996)
Hum Pathol
, vol.27
, pp. 1277-1281
-
-
Haque, S.1
Chandra, B.2
Gerber, M.A.3
Lok, A.S.4
-
44
-
-
0041382552
-
Iron as a co-morbid factor in nonhemochromatotic liver disease
-
Bonkovsky HL, Lambrecht RW, Shan Y. Iron as a co-morbid factor in nonhemochromatotic liver disease. Alcohol 2003;30: 137-44.
-
(2003)
Alcohol
, vol.30
, pp. 137-144
-
-
Bonkovsky, H.L.1
Lambrecht, R.W.2
Shan, Y.3
-
45
-
-
0028609224
-
Iron metabolism in inflammation
-
Konijn AM. Iron metabolism in inflammation. Baillieres Clin Haematol 1994; 7: 829-49.
-
(1994)
Baillieres Clin Haematol
, vol.7
, pp. 829-849
-
-
Konijn, A.M.1
-
46
-
-
2442426523
-
An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice
-
Roy CN, Custodio AO, de Graaf J, et al. An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice. Nat Genet 2004; 36: 481-5.
-
(2004)
Nat Genet
, vol.36
, pp. 481-485
-
-
Roy, C.N.1
Custodio, A.O.2
de Graaf, J.3
-
48
-
-
0025969686
-
Regulation of ferritin and heme oxygenase synthesis in rat fibroblasts by different forms of iron
-
Eisenstein RS, Garcia-Mayol D, Pettingell W, Munro HN. Regulation of ferritin and heme oxygenase synthesis in rat fibroblasts by different forms of iron. Proc Natl Acad Sci USA 1991; 88: 688-92.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 688-692
-
-
Eisenstein, R.S.1
Garcia-Mayol, D.2
Pettingell, W.3
Munro, H.N.4
-
49
-
-
0026657174
-
Ferritin: A cytoprotective antioxidant strategem of endothelium
-
Balla G, Jacob HS, Balla J, et al. Ferritin: a cytoprotective antioxidant strategem of endothelium. J Biol Chem 1992; 267: 18148-53.
-
(1992)
J Biol Chem
, vol.267
, pp. 18148-18153
-
-
Balla, G.1
Jacob, H.S.2
Balla, J.3
-
50
-
-
0027255106
-
Oxidative stress resulting from ultraviolet A irradiation of human skin fibroblasts leads to a heme oxygenasedependent increase in ferritin
-
Vile GF, Tyrrell RM. Oxidative stress resulting from ultraviolet A irradiation of human skin fibroblasts leads to a heme oxygenasedependent increase in ferritin. J Biol Chem 1993; 268: 14678-81.
-
(1993)
J Biol Chem
, vol.268
, pp. 14678-14681
-
-
Vile, G.F.1
Tyrrell, R.M.2
-
51
-
-
0345688910
-
Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages
-
Knutson MD, Vafa MR, Haile DJ, Wessling-Resnick M. Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages. Blood 2003; 102: 4191-7.
-
(2003)
Blood
, vol.102
, pp. 4191-4197
-
-
Knutson, M.D.1
Vafa, M.R.2
Haile, D.J.3
Wessling-Resnick, M.4
-
52
-
-
41649110613
-
Sequential regulation of ferroportin expression after erythrophagocytosis in murine macrophages: Early mRNA induction by haem, followed by iron-dependent protein expression
-
Delaby C, Pilard N, Puy H, Canonne-Hergaux F. Sequential regulation of ferroportin expression after erythrophagocytosis in murine macrophages: early mRNA induction by haem, followed by iron-dependent protein expression. Biochem J 2008; 411: 123-31.
-
(2008)
Biochem J
, vol.411
, pp. 123-131
-
-
Delaby, C.1
Pilard, N.2
Puy, H.3
Canonne-Hergaux, F.4
-
53
-
-
77953713414
-
Heme controls ferroportin 1(FPN1) transcription involving Bach1, Nrf2 and MARE/ARE sequence motif at position-7007 of the FPN1 promoter
-
Marro S, Chiabrando D, Messana E, et al. Heme controls ferroportin 1(FPN1) transcription involving Bach1, Nrf2 and MARE/ARE sequence motif at position-7007 of the FPN1 promoter. Haematologica 2010; 95: 1261-8.
-
(2010)
Haematologica
, vol.95
, pp. 1261-1268
-
-
Marro, S.1
Chiabrando, D.2
Messana, E.3
-
54
-
-
0023876497
-
Iron metabolism in the erythrophagocytosing Kupffer cell
-
Kondo H, Saito K, Grasso JP, Aisen P. Iron metabolism in the erythrophagocytosing Kupffer cell. Hepatology 1988; 8: 32-8.
-
(1988)
Hepatology
, vol.8
, pp. 32-38
-
-
Kondo, H.1
Saito, K.2
Grasso, J.P.3
Aisen, P.4
-
55
-
-
0032031707
-
Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase-2
-
Dennery PA, Spitz DR, Yang G, et al. Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase-2. J Clin Invest 1998; 101: 1001-11.
-
(1998)
J Clin Invest
, vol.101
, pp. 1001-1011
-
-
Dennery, P.A.1
Spitz, D.R.2
Yang, G.3
-
56
-
-
37349070339
-
Heme oxygenase-1 deficiency accelerates formation of arterial thrombosis through oxidative damage to the endothelium, which is rescued by inhaled carbon monoxide
-
True AL, Olive M, Boehm M, et al. Heme oxygenase-1 deficiency accelerates formation of arterial thrombosis through oxidative damage to the endothelium, which is rescued by inhaled carbon monoxide. Circ Res 2007; 101: 893-901.
-
(2007)
Circ Res
, vol.101
, pp. 893-901
-
-
True, A.L.1
Olive, M.2
Boehm, M.3
-
57
-
-
12244304860
-
Resistance to hyperoxia with heme oxygenase-1 disruption: Role of iron
-
Dennery PA, Visner G, Weng YH, et al. Resistance to hyperoxia with heme oxygenase-1 disruption: role of iron. Free Radic Biol Med 2003; 34: 124-33.
-
(2003)
Free Radic Biol Med
, vol.34
, pp. 124-133
-
-
Dennery, P.A.1
Visner, G.2
Weng, Y.H.3
-
58
-
-
66049098514
-
Myeloid heme oxygenase-1 regulates innate immunity and autoimmunity by modulating IFN-beta production
-
Tzima S, Victoratos P, Kranidioti K, Alexiou M, Kollias G. Myeloid heme oxygenase-1 regulates innate immunity and autoimmunity by modulating IFN-beta production. J Exp Med 2009; 206: 1167-79.
-
(2009)
J Exp Med
, vol.206
, pp. 1167-1179
-
-
Tzima, S.1
Victoratos, P.2
Kranidioti, K.3
Alexiou, M.4
Kollias, G.5
-
59
-
-
0031915553
-
Expression pattern of heme oxygenase isoenzymes 1 and 2 in normal and stress-exposed rat liver
-
Bauer I, Wanner GA, Rensing H, et al. Expression pattern of heme oxygenase isoenzymes 1 and 2 in normal and stress-exposed rat liver. Hepatology 1998; 27: 829-38.
-
(1998)
Hepatology
, vol.27
, pp. 829-838
-
-
Bauer, I.1
Wanner, G.A.2
Rensing, H.3
-
60
-
-
0032921697
-
Nitric oxide mediates the lipopolysaccharide dependent upregulation of the heme oxygenase-1 gene expression in cultured rat Kupffer cells
-
Immenschuh S, Tan M, Ramadori G. Nitric oxide mediates the lipopolysaccharide dependent upregulation of the heme oxygenase-1 gene expression in cultured rat Kupffer cells. J Hepatol 1999;30: 61-9.
-
(1999)
J Hepatol
, vol.30
, pp. 61-69
-
-
Immenschuh, S.1
Tan, M.2
Ramadori, G.3
-
61
-
-
0041967387
-
Different faces of the heme-heme oxygenase system in inflammation
-
Wagener FA, Volk HD, Willis D, et al. Different faces of the heme-heme oxygenase system in inflammation. Pharmacol Rev 2003; 55: 551-71.
-
(2003)
Pharmacol Rev
, vol.55
, pp. 551-571
-
-
Wagener, F.A.1
Volk, H.D.2
Willis, D.3
-
64
-
-
0036074141
-
Lipopolysaccharides in liver injury: Molecular mechanisms of Kupffer cell activation
-
Su GL. Lipopolysaccharides in liver injury: molecular mechanisms of Kupffer cell activation. Am J Physiol Gastrointest Liver Physiol 2002; 283: G256-65.
-
(2002)
Am J Physiol Gastrointest Liver Physiol
, vol.283
-
-
Su, G.L.1
-
65
-
-
33644544110
-
The liver as an immunological organ
-
Racanelli V, Rehermann B. The liver as an immunological organ. Hepatology 2006; 43: S54-62.
-
(2006)
Hepatology
, vol.43
, pp. 54-62
-
-
Racanelli, V.1
Rehermann, B.2
-
66
-
-
61949261267
-
Inflammatory pathways in liver homeostasis and liver injury
-
Tacke F, Luedde T, Trautwein C. Inflammatory pathways in liver homeostasis and liver injury. Clin Rev Allergy Immunol 2009; 36: 4-12.
-
(2009)
Clin Rev Allergy Immunol
, vol.36
, pp. 4-12
-
-
Tacke, F.1
Luedde, T.2
Trautwein, C.3
-
67
-
-
0036127426
-
Heme oxygenase-1 mediates the antiinflammatory effect of interleukin-10 in mice
-
Lee TS, Chau LY. Heme oxygenase-1 mediates the antiinflammatory effect of interleukin-10 in mice. Nat Med 2002; 8: 240-6.
-
(2002)
Nat Med
, vol.8
, pp. 240-246
-
-
Lee, T.S.1
Chau, L.Y.2
-
68
-
-
4344566310
-
Heme oxygenase-1 modulates early inflammatory responses: Evidence from the heme oxygenase-1-deficient mouse
-
Kapturczak MH, Wasserfall C, Brusko T, et al. Heme oxygenase-1 modulates early inflammatory responses: evidence from the heme oxygenase-1-deficient mouse. Am J Pathol 2004; 165: 1045-53.
-
(2004)
Am J Pathol
, vol.165
, pp. 1045-1053
-
-
Kapturczak, M.H.1
Wasserfall, C.2
Brusko, T.3
-
69
-
-
33846924300
-
How many transcription factors does it take to turn on the heme oxygenase-1 gene?
-
Alam J, Cook JL. How many transcription factors does it take to turn on the heme oxygenase-1 gene? Am J Respir Cell Mol Biol 2007; 36: 166-74.
-
(2007)
Am J Respir Cell Mol Biol
, vol.36
, pp. 166-174
-
-
Alam, J.1
Cook, J.L.2
-
70
-
-
33645530745
-
Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis
-
Thimmulappa RK, Lee H, Rangasamy T, et al. Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis. J Clin Invest 2006; 116: 984-95.
-
(2006)
J Clin Invest
, vol.116
, pp. 984-995
-
-
Thimmulappa, R.K.1
Lee, H.2
Rangasamy, T.3
-
71
-
-
57349116768
-
Coordinate regulation of enzyme markers for inflammation and for protection against oxidants and electrophiles
-
Liu H, Dinkova-Kostova AT, Talalay P. Coordinate regulation of enzyme markers for inflammation and for protection against oxidants and electrophiles. Proc Natl Acad Sci USA 2008; 105: 15926-31.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 15926-15931
-
-
Liu, H.1
Dinkova-Kostova, A.T.2
Talalay, P.3
-
72
-
-
33847050801
-
Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
-
Kensler TW, Wakabayashi N, Biswal S. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu Rev Pharmacol Toxicol 2007; 47: 89-116.
-
(2007)
Annu Rev Pharmacol Toxicol
, vol.47
, pp. 89-116
-
-
Kensler, T.W.1
Wakabayashi, N.2
Biswal, S.3
-
73
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant response elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
Itoh K, Wakabayashi N, Katoh Y, et al. Keap1 represses nuclear activation of antioxidant response elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev 1999; 13: 76-86.
-
(1999)
Genes Dev
, vol.13
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
-
74
-
-
14044254798
-
Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation
-
Kobayashi M, Yamamoto M. Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation. Antioxid Redox Signal 2005; 7: 385-94.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 385-394
-
-
Kobayashi, M.1
Yamamoto, M.2
-
75
-
-
77649265091
-
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
-
Komatsu M, Kurokawa H, Waguri S, et al. The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1. Nat Cell Biol 2010; 12: 213-23.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 213-223
-
-
Komatsu, M.1
Kurokawa, H.2
Waguri, S.3
-
76
-
-
0027953712
-
Differential effects of metalloporphyrins on messenger RNA levels of d-aminolevulinate synthase and heme oxygenase
-
Cable EE, Pepe JA, Karamtsios NC, Lambrecht RW, Bonkovsky HL. Differential effects of metalloporphyrins on messenger RNA levels of d-aminolevulinate synthase and heme oxygenase. J Clin Invest 1994; 94: 649-54.
-
(1994)
J Clin Invest
, vol.94
, pp. 649-654
-
-
Cable, E.E.1
Pepe, J.A.2
Karamtsios, N.C.3
Lambrecht, R.W.4
Bonkovsky, H.L.5
-
77
-
-
8544284074
-
The antioxidant defense protein heme oxygenase 1 is a novel target for statins in endothelial cells
-
Grosser N, Hemmerle A, Berndt G, et al. The antioxidant defense protein heme oxygenase 1 is a novel target for statins in endothelial cells. Free Radic Biol Med 2004; 37: 2064-2071.
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 2064-2071
-
-
Grosser, N.1
Hemmerle, A.2
Berndt, G.3
-
78
-
-
33750532308
-
Regulation of inflammation and redox signaling by dietary polyphenols
-
Rahman I, Biswas SK, Kirkham PA. Regulation of inflammation and redox signaling by dietary polyphenols. Biochem Pharmacol 2006; 72: 1439-52.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 1439-1452
-
-
Rahman, I.1
Biswas, S.K.2
Kirkham, P.A.3
-
79
-
-
34250753928
-
Activation of endothelial nitric oxide synthase by dietary isoflavones: Role of NO in Nrf2-mediated antioxidant gene expression
-
Mann GE, Rowlands DJ, Li FY, de Winter P, Siow RC. Activation of endothelial nitric oxide synthase by dietary isoflavones: role of NO in Nrf2-mediated antioxidant gene expression. Cardiovasc Res 2007; 75: 261-74.
-
(2007)
Cardiovasc Res
, vol.75
, pp. 261-274
-
-
Mann, G.E.1
Rowlands, D.J.2
Li, F.Y.3
de Winter, P.4
Siow, R.C.5
-
80
-
-
34347392509
-
Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf2 pathways
-
Yao P, Nussler A, Liu L, et al. Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf2 pathways. J Hepatol 2007; 47: 253-61.
-
(2007)
J Hepatol
, vol.47
, pp. 253-261
-
-
Yao, P.1
Nussler, A.2
Liu, L.3
-
81
-
-
67049145006
-
The protective role of HO-1 and its generated products (CO, bilirubin, and Fe) in ethanol-induced human hepatocyte damage
-
Yao P, Hao L, Nussler N, et al. The protective role of HO-1 and its generated products (CO, bilirubin, and Fe) in ethanol-induced human hepatocyte damage. Am J Physiol Gastrointest Liver Physiol 2009; 296: G1318-23.
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.296
-
-
Yao, P.1
Hao, L.2
Nussler, N.3
-
82
-
-
0032528947
-
Transcriptional activation of the haem oxygenase-1 gene by cGMP via a cAMP response element/activator protein-1 element in primary cultures of rat hepatocytes
-
Immenschuh S, Hinke V, Ohlmann A, Gifhorn-Katz S, Katz N, Jungermann K, Kietzmann T. Transcriptional activation of the haem oxygenase-1 gene by cGMP via a cAMP response element/activator protein-1 element in primary cultures of rat hepatocytes. Biochem J 1998; 334: 141-6.
-
(1998)
Biochem J
, vol.334
, pp. 141-146
-
-
Immenschuh, S.1
Hinke, V.2
Ohlmann, A.3
Gifhorn-Katz, S.4
Katz, N.5
Jungermann, K.6
Kietzmann, T.7
-
83
-
-
0031956516
-
The rat heme oxygenase-1 gene is transcriptionally induced via the protein kinase A signaling pathway in rat hepatocyte cultures
-
Immenschuh S, Kietzmann T, Hinke V, Wiederhold M, Katz N, Muller-Eberhard U. The rat heme oxygenase-1 gene is transcriptionally induced via the protein kinase A signaling pathway in rat hepatocyte cultures. Mol Pharmacol 1998; 53: 483-91.
-
(1998)
Mol Pharmacol
, vol.53
, pp. 483-491
-
-
Immenschuh, S.1
Kietzmann, T.2
Hinke, V.3
Wiederhold, M.4
Katz, N.5
Muller-Eberhard, U.6
-
84
-
-
77950625277
-
The antiinflammatory effects of adiponectin are mediated via a heme oxygenase-1-dependent pathway in rat Kupffer cells
-
Mandal P, Park PH, McMullen MR, Pratt BT, Nagy LE. The antiinflammatory effects of adiponectin are mediated via a heme oxygenase-1-dependent pathway in rat Kupffer cells. Hepatology 2010; 51: 1420-9.
-
(2010)
Hepatology
, vol.51
, pp. 1420-1429
-
-
Mandal, P.1
Park, P.H.2
McMullen, M.R.3
Pratt, B.T.4
Nagy, L.E.5
-
85
-
-
0037386113
-
Kupffer-cell specific induction of heme oxygenase 1 (hsp32) by the atrial natriuretic peptide--role of cGMP
-
Kiemer AK, Gerwig T, Gerbes AL, Meissner H, Bilzer M, Vollmar AM. Kupffer-cell specific induction of heme oxygenase 1 (hsp32) by the atrial natriuretic peptide--role of cGMP. J Hepatol; 38: 490-8.
-
J Hepatol
, vol.38
, pp. 490-498
-
-
Kiemer, A.K.1
Gerwig, T.2
Gerbes, A.L.3
Meissner, H.4
Bilzer, M.5
Vollmar, A.M.6
-
86
-
-
20444459893
-
Heme oxygenase-1 gene activation by the NAD(P)H oxidase inhibitor 4-(2-aminoethyl) benzenesulfonyl fluoride via a protein kinase B, p38-dependent signaling pathway in monocytes
-
Wijayanti N, Kietzmann T, Immenschuh S. Heme oxygenase-1 gene activation by the NAD(P)H oxidase inhibitor 4-(2-aminoethyl) benzenesulfonyl fluoride via a protein kinase B, p38-dependent signaling pathway in monocytes. J Biol Chem 2005; 280: 21820-9.
-
(2005)
J Biol Chem
, vol.280
, pp. 21820-21829
-
-
Wijayanti, N.1
Kietzmann, T.2
Immenschuh, S.3
-
87
-
-
77950601100
-
Therapeutic RNA manipulation in liver disease
-
Kerr TA, Davidson NO. Therapeutic RNA manipulation in liver disease. Hepatology 2010; 51: 1055-61.
-
(2010)
Hepatology
, vol.51
, pp. 1055-1061
-
-
Kerr, T.A.1
Davidson, N.O.2
-
88
-
-
0033452790
-
Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury
-
Amersi F, Buelow R, Kato H, et al. Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury. J Clin Invest 1999; 104: 1631-9.
-
(1999)
J Clin Invest
, vol.104
, pp. 1631-1639
-
-
Amersi, F.1
Buelow, R.2
Kato, H.3
-
89
-
-
56149124383
-
Heme oxygenase-1 suppresses hepatitis C virus replication and increases resistance of hepatocytes to oxidant injury
-
Zhu Z, Wilson AT, Mathahs MM, et al. Heme oxygenase-1 suppresses hepatitis C virus replication and increases resistance of hepatocytes to oxidant injury. Hepatology 2008; 48: 1430-9.
-
(2008)
Hepatology
, vol.48
, pp. 1430-1439
-
-
Zhu, Z.1
Wilson, A.T.2
Mathahs, M.M.3
-
90
-
-
34848878881
-
Reciprocal effects of micro-RNA-122 on expression of heme oxygenase-1 and hepatitis C virus genes in human hepatocytes
-
Shan Y, Zheng J, Lambrecht RW, Bonkovsky HL. Reciprocal effects of micro-RNA-122 on expression of heme oxygenase-1 and hepatitis C virus genes in human hepatocytes. Gastroenterology 2007; 133: 1166-74.
-
(2007)
Gastroenterology
, vol.133
, pp. 1166-1174
-
-
Shan, Y.1
Zheng, J.2
Lambrecht, R.W.3
Bonkovsky, H.L.4
-
91
-
-
77951460055
-
MicroRNA-196 represses Bach1 protein and hepatitis C virus gene expression in human hepatoma cells expressing hepatitis C viral proteins
-
Hou W, Tian Q, Zheng J, Bonkovsky HL. MicroRNA-196 represses Bach1 protein and hepatitis C virus gene expression in human hepatoma cells expressing hepatitis C viral proteins. Hepatology 2010; 51: 1494-504.
-
(2010)
Hepatology
, vol.51
, pp. 1494-1504
-
-
Hou, W.1
Tian, Q.2
Zheng, J.3
Bonkovsky, H.L.4
-
94
-
-
0036828783
-
Course and outcome of hepatitis C
-
Hoofnagle JH. Course and outcome of hepatitis C. Hepatology 2002; 36: S21-9.
-
(2002)
Hepatology
, vol.36
-
-
Hoofnagle, J.H.1
-
95
-
-
70349567521
-
Alcoholic liver disease and hepatitis C: A frequently underestimated combination
-
Mueller S, Millonig G, Seitz HK. Alcoholic liver disease and hepatitis C: a frequently underestimated combination. World J Gastroenterol 2009; 15: 3462-71.
-
(2009)
World J Gastroenterol
, vol.15
, pp. 3462-3471
-
-
Mueller, S.1
Millonig, G.2
Seitz, H.K.3
-
96
-
-
34848825909
-
Antiviral activity and hepatoprotection by heme oxygenase-1 in hepatitis B virus infection
-
Protzer U, Seyfried S, Quasdorff M, et al. Antiviral activity and hepatoprotection by heme oxygenase-1 in hepatitis B virus infection. Gastroenterology 2007; 133: 1156-65.
-
(2007)
Gastroenterology
, vol.133
, pp. 1156-1165
-
-
Protzer, U.1
Seyfried, S.2
Quasdorff, M.3
-
97
-
-
21744438136
-
Hepatitis C virus-core and non structural proteins lead to different effects on cellular antioxidant defenses
-
Abdalla MY, Ahmad IM, Spitz DR, Schmidt WN, Britigan BE. Hepatitis C virus-core and non structural proteins lead to different effects on cellular antioxidant defenses. J Med Virol 2005; 76: 489-97.
-
(2005)
J Med Virol
, vol.76
, pp. 489-497
-
-
Abdalla, M.Y.1
Ahmad, I.M.2
Spitz, D.R.3
Schmidt, W.N.4
Britigan, B.E.5
-
98
-
-
4444238755
-
Down-regulation of heme oxygenase-1 by hepatitis C virus infection in vivo and by the in vitro expression of hepatitis C core protein
-
Abdalla MY, Britigan BE, Wen F, et al. Down-regulation of heme oxygenase-1 by hepatitis C virus infection in vivo and by the in vitro expression of hepatitis C core protein. J Infect Dis 2004; 190: 1109-18.
-
(2004)
J Infect Dis
, vol.190
, pp. 1109-1118
-
-
Abdalla, M.Y.1
Britigan, B.E.2
Wen, F.3
-
99
-
-
33744942680
-
HCV proteins increase expression of heme oxygenase-1 (HO-1) and decrease expression of Bach1 in human hepatoma cells
-
Ghaziani T, Shan Y, Lambrecht RW, et al. HCV proteins increase expression of heme oxygenase-1 (HO-1) and decrease expression of Bach1 in human hepatoma cells. J Hepatol 2006; 45: 5-12.
-
(2006)
J Hepatol
, vol.45
, pp. 5-12
-
-
Ghaziani, T.1
Shan, Y.2
Lambrecht, R.W.3
-
100
-
-
75449117083
-
The heme oxygenase 1 product biliverdin interferes with hepatitis C virus replication by increasing antiviral interferon response
-
Lehmann E, El-Tantawy WH, Ocker M, et al. The heme oxygenase 1 product biliverdin interferes with hepatitis C virus replication by increasing antiviral interferon response. Hepatology 2010; 51: 398-404.
-
(2010)
Hepatology
, vol.51
, pp. 398-404
-
-
Lehmann, E.1
El-Tantawy, W.H.2
Ocker, M.3
-
102
-
-
0032451389
-
Alcoholic liver disease: Proposed recommendationss for the American College of Gastroenterology
-
McCullough AJ, O'Connor JFB. Alcoholic liver disease: proposed recommendationss for the American College of Gastroenterology. Am J Gastroenterol 1998; 93: 2022-36.
-
(1998)
Am J Gastroenterol
, vol.93
, pp. 2022-2036
-
-
McCullough, A.J.1
O'Connor, J.F.B.2
-
103
-
-
0036288123
-
Is obesity an independent risk factor for hepatocellular carcinoma in cirrhosis?
-
Nair S, Mason A, Eason J, Loss G, Perrillo RP. Is obesity an independent risk factor for hepatocellular carcinoma in cirrhosis? Hepatology 2002; 36: 150-5.
-
(2002)
Hepatology
, vol.36
, pp. 150-155
-
-
Nair, S.1
Mason, A.2
Eason, J.3
Loss, G.4
Perrillo, R.P.5
-
104
-
-
0042034405
-
Ethanol toxicity and nutritional status
-
In: Kotsonis F, Mackey M, Eds., 2nd ed. London. New York: Taylor and Francis
-
Seitz HK, Suter P. Ethanol toxicity and nutritional status. In: Kotsonis F, Mackey M, Eds. Nutritional Toxicology. 2nd ed. London. New York: Taylor and Francis; 2002. pp. 122-54.
-
(2002)
Nutritional Toxicology
, pp. 122-154
-
-
Seitz, H.K.1
Suter, P.2
-
105
-
-
0032185432
-
Alcoholic liver injury involves activation of Kupffer cells by endotoxin
-
Thurman RG. II. Alcoholic liver injury involves activation of Kupffer cells by endotoxin. Am J Physiol 1998; 275: G605-11.
-
(1998)
Am J Physiol
, vol.275
-
-
Thurman II, R.G.1
-
106
-
-
0034676629
-
Cytokines in alcoholic and nonalcoholic steatohepatitis
-
Tilg H, Diehl AM. Cytokines in alcoholic and nonalcoholic steatohepatitis. N Engl J Med 2000; 343: 1467-76.
-
(2000)
N Engl J Med
, vol.343
, pp. 1467-1476
-
-
Tilg, H.1
Diehl, A.M.2
-
107
-
-
0035834684
-
Stabilization of tumor necrosis factor alpha mRNA by chronic ethanol: Role of A + U-rich elements and p38 mitogen-activated protein kinase signaling pathway
-
Kishore R, McMullen MR, Nagy LE. Stabilization of tumor necrosis factor alpha mRNA by chronic ethanol: role of A + U-rich elements and p38 mitogen-activated protein kinase signaling pathway. J Biol Chem 2001; 276: 41930-7.
-
(2001)
J Biol Chem
, vol.276
, pp. 41930-41937
-
-
Kishore, R.1
McMullen, M.R.2
Nagy, L.E.3
-
108
-
-
0037376674
-
Oxidant signals and oxidative stress
-
Finkel T. Oxidant signals and oxidative stress. Curr Opin Cell Biol 2003; 15: 247-54.
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 247-254
-
-
Finkel, T.1
-
109
-
-
0041302377
-
The fatderived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
-
Xu A, Wang Y, Keshaw H, Xu LY, Lam KS, Cooper GJ. The fatderived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 2003; 112: 91-100.
-
(2003)
J Clin Invest
, vol.112
, pp. 91-100
-
-
Xu, A.1
Wang, Y.2
Keshaw, H.3
Xu, L.Y.4
Lam, K.S.5
Cooper, G.J.6
-
110
-
-
24144496133
-
Role of adiponectin in the protective action of dietary saturated fat against alcoholic fatty liver in mice
-
You M, Considine RV, Leone TC, Kelly DP, Crabb DW. Role of adiponectin in the protective action of dietary saturated fat against alcoholic fatty liver in mice. Hepatology 2005; 42: 568-77.
-
(2005)
Hepatology
, vol.42
, pp. 568-577
-
-
You, M.1
Considine, R.V.2
Leone, T.C.3
Kelly, D.P.4
Crabb, D.W.5
-
111
-
-
33645804223
-
Adiponectin normalizes LPS-stimulated TNF-alpha production by rat Kupffer cells after chronic ethanol feeding
-
Thakur V, Pritchard MT, McMullen MR, Nagy LE. Adiponectin normalizes LPS-stimulated TNF-alpha production by rat Kupffer cells after chronic ethanol feeding. Am J Physiol Gastrointest Liver Physiol 2006; 290: G998-1007.
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
, pp. 998-1007
-
-
Thakur, V.1
Pritchard, M.T.2
McMullen, M.R.3
Nagy, L.E.4
-
112
-
-
0033373209
-
Iron primes hepatic macrophages for NF-kappaB activation in alcoholic liver injury
-
Tsukamoto H, Lin M, Ohata M, Giulivi C, French SW, Brittenham G. Iron primes hepatic macrophages for NF-kappaB activation in alcoholic liver injury. Am J Physiol 1999; 277: G1240-50.
-
(1999)
Am J Physiol
, vol.277
-
-
Tsukamoto, H.1
Lin, M.2
Ohata, M.3
Giulivi, C.4
French, S.W.5
Brittenham, G.6
-
113
-
-
21644472266
-
Increased lipopolysaccharide sensitivity in alcoholic fatty livers is independent of leptin deficiency and toll-like receptor 4 (TLR4) or TLR2 mRNA expression
-
Romics L, Jr., Mandrekar P, Kodys K, et al. Increased lipopolysaccharide sensitivity in alcoholic fatty livers is independent of leptin deficiency and toll-like receptor 4 (TLR4) or TLR2 mRNA expression. Alcohol Clin Exp Res 2005; 29: 1018-26.
-
(2005)
Alcohol Clin Exp Res
, vol.29
, pp. 1018-1026
-
-
Romics Jr., L.1
Mandrekar, P.2
Kodys, K.3
-
114
-
-
34447134884
-
Heme oxygenase-1 upregulated by Ginkgo biloba extract: Potential protection against ethanol-induced oxidative liver damage
-
Yao P, Li K, Song F, et al. Heme oxygenase-1 upregulated by Ginkgo biloba extract: potential protection against ethanol-induced oxidative liver damage. Food Chem Toxicol 2007; 45: 1333-42.
-
(2007)
Food Chem Toxicol
, vol.45
, pp. 1333-1342
-
-
Yao, P.1
Li, K.2
Song, F.3
-
115
-
-
77649189669
-
Curcumin alleviates ethanol-induced hepatocytes oxidative damage involving heme oxygenase-1 induction
-
Bao W, Li K, Rong S, et al. Curcumin alleviates ethanol-induced hepatocytes oxidative damage involving heme oxygenase-1 induction. J Ethnopharmacol 2010; 128: 549-53.
-
(2010)
J Ethnopharmacol
, vol.128
, pp. 549-553
-
-
Bao, W.1
Li, K.2
Rong, S.3
-
116
-
-
77950625277
-
The antiinflammatory effects of adiponectin are mediated via a heme oxygenase-1-dependent pathway in rat Kupffer cells
-
Mandal P, Park PH, McMullen MR, Pratt BT, Nagy LE. The antiinflammatory effects of adiponectin are mediated via a heme oxygenase-1-dependent pathway in rat Kupffer cells. Hepatology 2010; 51: 1420-9.
-
(2010)
Hepatology
, vol.51
, pp. 1420-1429
-
-
Mandal, P.1
Park, P.H.2
McMullen, M.R.3
Pratt, B.T.4
Nagy, L.E.5
-
117
-
-
0035083842
-
Nonalcoholic steatohepatitis: Definition and pathology
-
Brunt EM. Nonalcoholic steatohepatitis: definition and pathology. Semin Liver Dis 2001; 21: 3-16.
-
(2001)
Semin Liver Dis
, vol.21
, pp. 3-16
-
-
Brunt, E.M.1
-
119
-
-
0036829092
-
AGA technical review on nonalcoholic fatty liver disease
-
Sanyal AJ. AGA technical review on nonalcoholic fatty liver disease. Gastroenterology 2002; 123: 1705-25.
-
(2002)
Gastroenterology
, vol.123
, pp. 1705-1725
-
-
Sanyal, A.J.1
-
121
-
-
0023801758
-
Alcohol-like liver disease in nonalcoholics. A clinical and histologic comparison with alcoholinduced liver injury
-
Diehl AM, Goodman Z, Ishak KG. Alcohol-like liver disease in nonalcoholics. A clinical and histologic comparison with alcoholinduced liver injury. Gastroenterology 1988; 95: 1056-62.
-
(1988)
Gastroenterology
, vol.95
, pp. 1056-1062
-
-
Diehl, A.M.1
Goodman, Z.2
Ishak, K.G.3
-
122
-
-
0037129380
-
Nonalcoholic fatty liver disease
-
Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002; 346: 1221-31.
-
(2002)
N Engl J Med
, vol.346
, pp. 1221-1231
-
-
Angulo, P.1
-
123
-
-
0033231294
-
Association of nonalcoholic fatty liver disease with insulin resistance
-
Marchesini G, Brizi M, Morselli-Labate AM, et al. Association of nonalcoholic fatty liver disease with insulin resistance. Am J Med 1999; 107: 450-5.
-
(1999)
Am J Med
, vol.107
, pp. 450-455
-
-
Marchesini, G.1
Brizi, M.2
Morselli-Labate, A.M.3
-
124
-
-
0030061922
-
IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha-and obesity-induced insulin resistance
-
Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha-and obesity-induced insulin resistance. Science 1996; 271: 665-8.
-
(1996)
Science
, vol.271
, pp. 665-668
-
-
Hotamisligil, G.S.1
Peraldi, P.2
Budavari, A.3
Ellis, R.4
White, M.F.5
Spiegelman, B.M.6
-
125
-
-
0036154816
-
NASH: From liver diseases to metabolic disorders and back to clinical hepatology
-
Marchesini G, Forlani G. NASH: from liver diseases to metabolic disorders and back to clinical hepatology. Hepatology 2002; 35: 497-9.
-
(2002)
Hepatology
, vol.35
, pp. 497-499
-
-
Marchesini, G.1
Forlani, G.2
-
126
-
-
0035084699
-
Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities
-
Sanyal AJ, Campbell-Sargent C, Mirshahi F, et al. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology 2001; 120: 1183-92.
-
(2001)
Gastroenterology
, vol.120
, pp. 1183-1192
-
-
Sanyal, A.J.1
Campbell-Sargent, C.2
Mirshahi, F.3
-
127
-
-
0344011135
-
Antioxidant paraoxonase 1 activity in the metabolic syndrome
-
Senti M, Tomas M, Fito M, et al. Antioxidant paraoxonase 1 activity in the metabolic syndrome. J Clin Endocrinol Metab 2003; 88: 5422-6.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 5422-5426
-
-
Senti, M.1
Tomas, M.2
Fito, M.3
-
128
-
-
14844288046
-
Heme oxygenase-1 levels and oxidative stress-related parameters in non-alcoholic fatty liver disease patients
-
Malaguarnera L, Madeddu R, Palio E, Arena N, Malaguarnera M. Heme oxygenase-1 levels and oxidative stress-related parameters in non-alcoholic fatty liver disease patients. J Hepatol 2005; 42: 585-91.
-
(2005)
J Hepatol
, vol.42
, pp. 585-591
-
-
Malaguarnera, L.1
Madeddu, R.2
Palio, E.3
Arena, N.4
Malaguarnera, M.5
-
129
-
-
69049107570
-
Effect of dietary fat to produce non-alcoholic fatty liver in the rat
-
Ahmed U, Redgrave TG, Oates PS. Effect of dietary fat to produce non-alcoholic fatty liver in the rat. J Gastroenterol Hepatol 2009; 24: 1463-71.
-
(2009)
J Gastroenterol Hepatol
, vol.24
, pp. 1463-1471
-
-
Ahmed, U.1
Redgrave, T.G.2
Oates, P.S.3
-
130
-
-
75149160667
-
Heme oxygenase-1 protects against steatohepatitis in both cultured hepatocytes and mice
-
Yu J, Chu ES, Wang R, et al. Heme oxygenase-1 protects against steatohepatitis in both cultured hepatocytes and mice. Gastroenterology 2010; 138: 694-704.
-
(2010)
Gastroenterology
, vol.138
, pp. 694-704
-
-
Yu, J.1
Chu, E.S.2
Wang, R.3
-
131
-
-
72649103895
-
Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis
-
Chowdhry S, Nazmy MH, Meakin PJ, et al. Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis. Free Radic Biol Med 2010; 48: 357-71.
-
(2010)
Free Radic Biol Med
, vol.48
, pp. 357-371
-
-
Chowdhry, S.1
Nazmy, M.H.2
Meakin, P.J.3
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