메뉴 건너뛰기




Volumn 25, Issue 1, 2013, Pages 114-118

Osteoarthritis, inflammation and obesity

Author keywords

Adipokines; inflammation; metabolic syndrome; obesity; osteoarthritis

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; BIOLOGICAL MARKER; CHEMERIN; COLLAGENASE 3; CXCL9 CHEMOKINE; CYCLOOXYGENASE 2; FIBROBLAST GROWTH FACTOR 2; GELATINASE B; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; INTERSTITIAL COLLAGENASE; LEPTIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; NITRIC OXIDE; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PROSTAGLANDIN E2; RESISTIN; STROMELYSIN; TOLL LIKE RECEPTOR 4;

EID: 84871252069     PISSN: 10408711     EISSN: 15316963     Source Type: Journal    
DOI: 10.1097/BOR.0b013e32835a9414     Document Type: Review
Times cited : (221)

References (48)
  • 1
    • 72149116709 scopus 로고    scopus 로고
    • Risk factors for onset of osteoarthritis of the knee in older adults: A systematic review and meta-analysis
    • Blagojevic M, Jinks C, Jeffery A, Jordan KP. Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis. Osteoarthritis Cartilage 2010; 18:24-33.
    • (2010) Osteoarthritis Cartilage , vol.18 , pp. 24-33
    • Blagojevic, M.1    Jinks, C.2    Jeffery, A.3    Jordan, K.P.4
  • 3
    • 78650983649 scopus 로고    scopus 로고
    • Role of proinflammatory cytokines in the pathophysiology of osteoarthritis
    • Kapoor M, Martel-Pelletier J, Lajeunesse D, et al. Role of proinflammatory cytokines in the pathophysiology of osteoarthritis. Nat Rev Rheumatol 2011; 7:33-42.
    • (2011) Nat Rev Rheumatol , vol.7 , pp. 33-42
    • Kapoor, M.1    Martel-Pelletier, J.2    Lajeunesse, D.3
  • 4
    • 77950302564 scopus 로고    scopus 로고
    • Association between weight or body mass index and hand osteoarthritis: A systematic review
    • Yusuf E, Nelissen RG, Ioan-Facsinay A, et al. Association between weight or body mass index and hand osteoarthritis: a systematic review. Ann Rheum Dis 2010; 69:761-765.
    • (2010) Ann Rheum Dis , vol.69 , pp. 761-765
    • Yusuf, E.1    Nelissen, R.G.2    Ioan-Facsinay, A.3
  • 5
    • 78650982382 scopus 로고    scopus 로고
    • Obesity punches above its weight in osteoarthritis
    • Aspden RM. Obesity punches above its weight in osteoarthritis. Nat Rev Rheumatol 2011; 7:65-68.
    • (2011) Nat Rev Rheumatol , vol.7 , pp. 65-68
    • Aspden, R.M.1
  • 6
    • 33750344131 scopus 로고    scopus 로고
    • Obesity and osteoarthritis: More complex than predicted!
    • Pottie P, Presle N, Terlain B, et al. Obesity and osteoarthritis: more complex than predicted! Ann Rheum Dis 2006; 65:1403-1405.
    • (2006) Ann Rheum Dis , vol.65 , pp. 1403-1405
    • Pottie, P.1    Presle, N.2    Terlain, B.3
  • 7
    • 80052409973 scopus 로고    scopus 로고
    • What's new in our understanding of the role ofadipokines in rheumatic diseases?
    • Gomez R, Conde J, Scotece M, et al. What's new in our understanding of the role ofadipokines in rheumatic diseases? Nat Rev Rheumatol 2011; 7:528-536.
    • (2011) Nat Rev Rheumatol , vol.7 , pp. 528-536
    • Gomez, R.1    Conde, J.2    Scotece, M.3
  • 8
    • 70349780614 scopus 로고    scopus 로고
    • Knee osteoarthritis in obese women with cardiometabolic clustering
    • Sowers M, Karvonen-Gutierrez CA, Palmieri-Smith R, et al. Knee osteoarthritis in obese women with cardiometabolic clustering. Arthritis Rheum 2009; 61:1328-1336.
    • (2009) Arthritis Rheum , vol.61 , pp. 1328-1336
    • Sowers, M.1    Karvonen-Gutierrez, C.A.2    Palmieri-Smith, R.3
  • 9
    • 79959341732 scopus 로고    scopus 로고
    • Osteoarthritis: An update with relevance for clinical practice
    • Bijlsma JW, Berenbaum F, Lafeber FP. Osteoarthritis: an update with relevance for clinical practice. Lancet 2011;377:2115-2126.
    • (2011) Lancet , vol.377 , pp. 2115-2126
    • Bijlsma, J.W.1    Berenbaum, F.2    Lafeber, F.P.3
  • 10
    • 84855993582 scopus 로고    scopus 로고
    • Biomechanical factors in osteoarthritis
    • Guilak F. Biomechanical factors in osteoarthritis. Best Pract Res Clin Rheu-matol 2011; 25:815-823.
    • (2011) Best Pract Res Clin Rheu-matol , vol.25 , pp. 815-823
    • Guilak, F.1
  • 11
    • 84868665627 scopus 로고    scopus 로고
    • Induction of the chemokine IL-8/Kc by the articular cartilage: Possible influence on osteoarthritis
    • in press
    • Chauffier K, Laiguillon MC, Bougault C, et al. Induction of the chemokine IL-8/Kc by the articular cartilage: possible influence on osteoarthritis. Joint Bone Spine 2012 (in press).
    • (2012) Joint Bone Spine
    • Chauffier, K.1    Laiguillon, M.C.2    Bougault, C.3
  • 12
    • 80052044389 scopus 로고    scopus 로고
    • Role of heme oxygenase-1 in inflammatory response induced by mechanical stretch in synovial cells
    • Takao M, Okinaga T, Ariyoshi W, et al. Role of heme oxygenase-1 in inflammatory response induced by mechanical stretch in synovial cells. Inflamm Res 2011; 60:861-867.
    • (2011) Inflamm Res , vol.60 , pp. 861-867
    • Takao, M.1    Okinaga, T.2    Ariyoshi, W.3
  • 13
    • 79955917012 scopus 로고    scopus 로고
    • Combined effects of TNF-alpha, IL-1beta, and HIF-1alpha on MMP-2 production in ACL fibroblasts under mechanical stretch: An in vitro study
    • Wang Y, Tang Z, Xue R, et al. Combined effects of TNF-alpha, IL-1beta, and HIF-1alpha on MMP-2 production in ACL fibroblasts under mechanical stretch: an in vitro study. J Orthop Res 2011; 29:1008-1014.
    • (2011) J Orthop Res , vol.29 , pp. 1008-1014
    • Wang, Y.1    Tang, Z.2    Xue, R.3
  • 14
    • 39749159713 scopus 로고    scopus 로고
    • Phenotypic characterization of osteoblasts from the sclerotic zones of osteoarthritic subchondral bone
    • Sanchez C, Deberg MA, Bellahcene A, et al. Phenotypic characterization of osteoblasts from the sclerotic zones of osteoarthritic subchondral bone. Arthritis Rheum 2008; 58:442-455.
    • (2008) Arthritis Rheum , vol.58 , pp. 442-455
    • Sanchez, C.1    Deberg, M.A.2    Bellahcene, A.3
  • 15
    • 84866178774 scopus 로고    scopus 로고
    • Regulation of subchondral bone osteoblast metabolism by cyclic compression
    • Sanchez C, Pesesse L, Gabay O, et al. Regulation of subchondral bone osteoblast metabolism by cyclic compression. Arthritis Rheum 2012; 64:1193-1203.
    • (2012) Arthritis Rheum , vol.64 , pp. 1193-1203
    • Sanchez, C.1    Pesesse, L.2    Gabay, O.3
  • 16
    • 84860517649 scopus 로고    scopus 로고
    • High dietary fat and the development of osteoarthritis in a rabbit model
    • Brunner AM, Henn CM, Drewniak EI, et al. High dietary fat and the development of osteoarthritis in a rabbit model. Osteoarthritis Cartilage 2012; 20:584-592.
    • (2012) Osteoarthritis Cartilage , vol.20 , pp. 584-592
    • Brunner, A.M.1    Henn, C.M.2    Drewniak, E.I.3
  • 17
    • 84869056284 scopus 로고    scopus 로고
    • Diet-induced obesity significantly increasestheseverity of posttraumaticarthritis in mice
    • Louer CR, Furman BD, Huebner JL, et al. Diet-induced obesity significantly increasestheseverity of posttraumaticarthritis in mice. Arthritis Rheum 2012; 64:3220-3230.
    • (2012) Arthritis Rheum , vol.64 , pp. 3220-3230
    • Louer, C.R.1    Furman, B.D.2    Huebner, J.L.3
  • 18
    • 82755190435 scopus 로고    scopus 로고
    • High-fatdietacceleratesprogression of osteoarthritis after meniscal/ligamentous injury
    • Mooney RA, Sampson ER, Lerea J, et al. High-fatdietacceleratesprogression of osteoarthritis after meniscal/ligamentous injury. Arthritis Res Ther 2011; 13:R198.
    • (2011) Arthritis Res Ther , vol.13
    • Mooney, R.A.1    Sampson, E.R.2    Lerea, J.3
  • 19
    • 84866174268 scopus 로고    scopus 로고
    • Metabolic stress-induced inflammation plays a major role in the development of osteoarthritis in mice
    • Gierman LM, van der Ham F, Koudijs A, et al. Metabolic stress-induced inflammation plays a major role in the development of osteoarthritis in mice. Arthritis Rheum 2012; 64:1172-1181.
    • (2012) Arthritis Rheum , vol.64 , pp. 1172-1181
    • Gierman, L.M.1    Van Der Ham, F.2    Koudijs, A.3
  • 20
    • 84856368496 scopus 로고    scopus 로고
    • Induction of osteoarthritis and metabolic inflammation by a very high-fat diet in mice: Effects of short-term exercise
    • Griffin TM, Huebner JL, Kraus VB, et al. Induction of osteoarthritis and metabolic inflammation by a very high-fat diet in mice: effects of short-term exercise. Arthritis Rheum 2012; 64:443-453.
    • (2012) Arthritis Rheum , vol.64 , pp. 443-453
    • Griffin, T.M.1    Huebner, J.L.2    Kraus, V.B.3
  • 21
    • 84857985148 scopus 로고    scopus 로고
    • Thecellularand signaling networks linking the immune system and metabolism in disease
    • Osborn O, Olefsky JM. Thecellularand signaling networks linking the immune system and metabolism in disease. Nat Med 2012; 18:363-374.
    • (2012) Nat Med , vol.18 , pp. 363-374
    • Osborn, O.1    Olefsky, J.M.2
  • 22
    • 84860425185 scopus 로고    scopus 로고
    • Adipokines and osteoarthritis: Novel molecules involved in the pathogenesis and progression of disease
    • Conde J, Scotece M, Gomez R, et al. Adipokines and osteoarthritis: novel molecules involved in the pathogenesis and progression of disease. Arthritis 2011; 2011:203901.
    • (2011) Arthritis , vol.2011 , pp. 203901
    • Conde, J.1    Scotece, M.2    Gomez, R.3
  • 23
    • 74249094016 scopus 로고    scopus 로고
    • Adipokines in arthritis: New kids on the block
    • Gabay O, Berenbaum F. Adipokines in arthritis: new kids on the block. Curr Rheumatol Rev 2009; 5:226-232.
    • (2009) Curr Rheumatol Rev , vol.5 , pp. 226-232
    • Gabay, O.1    Berenbaum, F.2
  • 24
    • 84861634211 scopus 로고    scopus 로고
    • The relationship between hand osteoarthritis and serum leptin concentration in participants ofthe Third National Health and Nutrition Examination Survey
    • Massengale M, Reichmann WM, Losina E, et al. The relationship between hand osteoarthritis and serum leptin concentration in participants ofthe Third National Health and Nutrition Examination Survey. Arthritis Res Ther 2012; 14:R132.
    • (2012) Arthritis Res Ther , vol.14
    • Massengale, M.1    Reichmann, W.M.2    Losina, E.3
  • 25
    • 78049314118 scopus 로고    scopus 로고
    • Chemerin: Atthe crossroads of inflammation and obesity
    • Ernst MC, Sinal CJ. Chemerin: atthe crossroads of inflammation and obesity. Trends Endocrinol Metab 2010; 21:660-667.
    • (2010) Trends Endocrinol Metab , vol.21 , pp. 660-667
    • Ernst, M.C.1    Sinal, C.J.2
  • 26
    • 79954611129 scopus 로고    scopus 로고
    • Chemerin/Chem R23 pathway: A system beyond chemokines
    • Iannone F, Lapadula G. Chemerin/Chem R23 pathway: a system beyond chemokines. Arthritis Res Ther 2011; 13:104.
    • (2011) Arthritis Res Ther , vol.13 , pp. 104
    • Iannone, F.1    Lapadula, G.2
  • 27
    • 84863012616 scopus 로고    scopus 로고
    • Association of chemerin levels in synovial fluid with the severity of knee osteoarthritis
    • Huang K, Du G, Li L, et al. Association of chemerin levels in synovial fluid with the severity of knee osteoarthritis. Biomarkers 2012; 17:16-20.
    • (2012) Biomarkers , vol.17 , pp. 16-20
    • Du Huang, K.G.1    Li, L.2
  • 28
    • 78650591267 scopus 로고    scopus 로고
    • Human articularchondrocytes express Chem R23 and chemerin; Chem R23 promotes inflammatory signalling upon binding the ligand chemerin(21-157)
    • Berg V, Sveinbjornsson B, Bendiksen S, et al. Human articularchondrocytes express Chem R23 and chemerin; Chem R23 promotes inflammatory signalling upon binding the ligand chemerin(21-157). Arthritis Res Ther 2010; 12:R228.
    • (2010) Arthritis Res Ther , vol.12
    • Berg, V.1    Sveinbjornsson, B.2    Bendiksen, S.3
  • 29
    • 82155168595 scopus 로고    scopus 로고
    • Chemerin induces CCL2 and TLR4 in synovial fibroblasts of patients with rheumatoid arthritis and osteoarthritis
    • Eisinger K, Bauer S, Schaffler A, et al. Chemerin induces CCL2 and TLR4 in synovial fibroblasts of patients with rheumatoid arthritis and osteoarthritis. Exp Mol Pathol 2012; 92:90-96.
    • (2012) Exp Mol Pathol , vol.92 , pp. 90-96
    • Eisinger, K.1    Bauer, S.2    Schaffler, A.3
  • 30
    • 0242552925 scopus 로고    scopus 로고
    • Evidence for a key role of leptin in osteoarthritis
    • Dumond H, Presle N, Terlain B, et al. Evidence for a key role of leptin in osteoarthritis. Arthritis Rheum 2003; 48:3118-3129.
    • (2003) Arthritis Rheum , vol.48 , pp. 3118-3129
    • Dumond, H.1    Presle, N.2    Terlain, B.3
  • 31
    • 84857239741 scopus 로고    scopus 로고
    • Leptin produced byjointwhite adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases
    • Hui W, Litherland GJ, Elias MS, et al. Leptin produced byjointwhite adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases. Ann Rheum Dis 2012; 71:455-462.
    • (2012) Ann Rheum Dis , vol.71 , pp. 455-462
    • Hui, W.1    Litherland, G.J.2    Elias, M.S.3
  • 32
    • 43949131087 scopus 로고    scopus 로고
    • Crucial role of visfatin/pre-B cell colony-enhancing factor in matrixdegradation and prostaglandin E2 synthesis in chondrocytes: Possible influence on osteoarthritis
    • Gosset M, Berenbaum F, Salvat C, et al. Crucial role of visfatin/pre-B cell colony-enhancing factor in matrixdegradation and prostaglandin E2 synthesis in chondrocytes: possible influence on osteoarthritis. Arthritis Rheum 2008; 58:1399-1409.
    • (2008) Arthritis Rheum , vol.58 , pp. 1399-1409
    • Gosset, M.1    Berenbaum, F.2    Salvat, C.3
  • 33
    • 84860356619 scopus 로고    scopus 로고
    • Proinflammatory actions of visfatin/nicotinamide phosphoribosyltransferase (Nampt) involve regulation of insulin signaling pathway and Nampt enzymatic activity
    • Jacques C, Holzenberger M, Mladenovic Z, et al. Proinflammatory actions of visfatin/nicotinamide phosphoribosyltransferase (Nampt) involve regulation of insulin signaling pathway and Nampt enzymatic activity. J Biol Chem 2012; 287:15100-15108.
    • (2012) J Biol Chem , vol.287 , pp. 15100-15108
    • Jacques, C.1    Holzenberger, M.2    Mladenovic, Z.3
  • 34
    • 84856291934 scopus 로고    scopus 로고
    • Extracellular nicotinamide phosphoribosyltransfer-ase (NAMPTvisfatin) inhibits insulin-like growth factor-1 signaling and pro-teoglycan synthesis in human articularchondrocytes
    • Yammani RR, Loeser RF. Extracellular nicotinamide phosphoribosyltransfer- ase (NAMPT/visfatin) inhibits insulin-like growth factor-1 signaling and pro-teoglycan synthesis in human articularchondrocytes. Arthritis Res Ther2012; 14:R23.
    • (2012) Arthritis Res Ther , vol.14
    • Yammani, R.R.1    Loeser, R.F.2
  • 36
    • 80051944902 scopus 로고    scopus 로고
    • Association between the chondrocyte phenotype and the expression of adipokines and their receptors: Evidence for a role of leptin but not adiponectin in the expression of cartilage-specific markers
    • Francin PJ, Guillaume C, Humbert AC, et al. Association between the chondrocyte phenotype and the expression of adipokines and their receptors: evidence for a role of leptin but not adiponectin in the expression of cartilage-specific markers. J Cell Physiol 2011; 226:2790-2797.
    • (2011) J Cell Physiol , vol.226 , pp. 2790-2797
    • Francin, P.J.1    Guillaume, C.2    Humbert, A.C.3
  • 37
    • 80052026269 scopus 로고    scopus 로고
    • Recent advances in biomarkers in osteoarthritis
    • Patra D, Sandell LJ. Recent advances in biomarkers in osteoarthritis. Curr Opin Rheumatol 2011; 23:465-470.
    • (2011) Curr Opin Rheumatol , vol.23 , pp. 465-470
    • Patra, D.1    Sandell, L.J.2
  • 38
    • 79957629294 scopus 로고    scopus 로고
    • Association between leptin, adiponectin and resistin and long-term progression of hand osteoarthritis
    • Yusuf E, Ioan-Facsinay A, Bijsterbosch J, et al. Association between leptin, adiponectin and resistin and long-term progression of hand osteoarthritis. Ann Rheum Dis 2011; 70:1282-1284.
    • (2011) Ann Rheum Dis , vol.70 , pp. 1282-1284
    • Yusuf, E.1    Ioan-Facsinay, A.2    Bijsterbosch, J.3
  • 39
    • 84856412071 scopus 로고    scopus 로고
    • Serum resistin level is associated with radiographic changes in hand osteoarthritis: Cross-sectional study
    • Choe JY, Bae J, Jung HY, et al. Serum resistin level is associated with radiographic changes in hand osteoarthritis: cross-sectional study. Joint Bone Spine 2012; 79:160-165.
    • (2012) Joint Bone Spine , vol.79 , pp. 160-165
    • Choe, J.Y.1    Bae, J.2    Jung, H.Y.3
  • 40
    • 79953701048 scopus 로고    scopus 로고
    • Temporal relationship between serum adipokines, biomarkers of bone and cartilage turnover, and cartilage volume loss in a population with clinical knee osteoarthritis
    • Berry PA, Jones SW, Cicuttini FM, et al. Temporal relationship between serum adipokines, biomarkers of bone and cartilage turnover, and cartilage volume loss in a population with clinical knee osteoarthritis. Arthritis Rheum 2011; 63:700-707.
    • (2011) Arthritis Rheum , vol.63 , pp. 700-707
    • Berry, P.A.1    Jones, S.W.2    Cicuttini, F.M.3
  • 41
    • 81055126964 scopus 로고    scopus 로고
    • Adiponectin associates with markers of cartilage degradation in osteoarthritis and induces production of pro-inflammatory and catabolic factors through mitogen-activated protein kinase pathways
    • Koskinen A, Juslin S, Nieminen R, et al. Adiponectin associates with markers of cartilage degradation in osteoarthritis and induces production of pro-inflammatory and catabolic factors through mitogen-activated protein kinase pathways. Arthritis Res Ther 2011; 13:R184.
    • (2011) Arthritis Res Ther , vol.13
    • Koskinen, A.1    Juslin, S.2    Nieminen, R.3
  • 42
    • 84863001000 scopus 로고    scopus 로고
    • Serum adipokines in osteo-arthritis; Comparison with controls and relationship with local parameters of synovial inflammation and cartilage damage
    • De Boer TN, van Spil WE, Huisman AM, et al. Serum adipokines in osteo-arthritis; comparison with controls and relationship with local parameters of synovial inflammation and cartilage damage. Osteoarthritis Cartilage 2012; 20:846-853.
    • (2012) Osteoarthritis Cartilage , vol.20 , pp. 846-853
    • De Boer, T.N.1    Van Spil, W.E.2    Huisman, A.M.3
  • 43
    • 77954215796 scopus 로고    scopus 로고
    • The infrapatellar fatpad should beconsidered asanactiveosteoarthriticjointtissue:anarrative review
    • Clockaerts S, Bastiaansen-Jenniskens YM, Runhaar J, et al. The infrapatellar fatpad should beconsidered asanactiveosteoarthriticjointtissue: anarrative review. Osteoarthritis Cartilage 2010; 18:876-882.
    • (2010) Osteoarthritis Cartilage , vol.18 , pp. 876-882
    • Clockaerts, S.1    Bastiaansen-Jenniskens, Y.M.2    Runhaar, J.3
  • 44
    • 79953297921 scopus 로고    scopus 로고
    • The infrapatellar fat pad of patients with osteoarthritis has an inflammatory phenotype
    • Klein-Wieringa IR, Kloppenburg M, Bastiaansen-Jenniskens YM, et al. The infrapatellar fat pad of patients with osteoarthritis has an inflammatory phenotype. Ann Rheum Dis 2011; 70:851-857.
    • (2011) Ann Rheum Dis , vol.70 , pp. 851-857
    • Klein-Wieringa, I.R.1    Kloppenburg, M.2    Bastiaansen-Jenniskens, Y.M.3
  • 45
    • 80052328640 scopus 로고    scopus 로고
    • Microarray analysis of the infra-patellar fat pad in knee osteoarthritis: Relationship with joint inflammation
    • Gandhi R, Takahashi M, Virtanen C, et al. Microarray analysis of the infra-patellar fat pad in knee osteoarthritis: relationship with joint inflammation. J Rheumatol 2011; 38:1966-1972.
    • (2011) J Rheumatol , vol.38 , pp. 1966-1972
    • Gandhi, R.1    Takahashi, M.2    Virtanen, C.3
  • 46
    • 84860919318 scopus 로고    scopus 로고
    • Cytokine production by infrapatellarfat pad can be stimulated by interleukin 1betaand inhibited by peroxisome proliferator activated receptor alpha agonist
    • Clockaerts S, Bastiaansen-Jenniskens YM, Feijt C, et al. Cytokine production by infrapatellarfat pad can be stimulated by interleukin 1betaand inhibited by peroxisome proliferator activated receptor alpha agonist. Ann Rheum Dis 2012; 71:1012-1018.
    • (2012) Ann Rheum Dis , vol.71 , pp. 1012-1018
    • Clockaerts, S.1    Bastiaansen-Jenniskens, Y.M.2    Feijt, C.3
  • 47
    • 84855387118 scopus 로고    scopus 로고
    • Infrapatellarfatpad of patientswith end-stage osteoarthritis inhibits catabolic mediators in cartilage
    • Bastiaansen-Jenniskens YM, Clockaerts S, Feijt C, et al. Infrapatellarfatpad of patientswith end-stage osteoarthritis inhibits catabolic mediators in cartilage. Ann Rheum Dis 2011; 71:288-294.
    • (2011) Ann Rheum Dis , vol.71 , pp. 288-294
    • Bastiaansen-Jenniskens, Y.M.1    Clockaerts, S.2    Feijt, C.3
  • 48
    • 78650676944 scopus 로고    scopus 로고
    • Benefits of massive weight loss on symptoms, systemic inflammation and cartilage turnover in obese patients with knee osteoarthritis
    • Richette P, Poitou C, Garnero P, et al. Benefits of massive weight loss on symptoms, systemic inflammation and cartilage turnover in obese patients with knee osteoarthritis. Ann Rheum Dis 2011; 70:139-144.
    • (2011) Ann Rheum Dis , vol.70 , pp. 139-144
    • Richette, P.1    Poitou, C.2    Garnero, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.