Neuroprotective effects of tert-butylhydroquinone on paraquat-induced dopaminergic cell degeneration in C57BL/6 mice and in PC12 cells

Archives of Toxicology

Volumn 86, Issue 11, 2012, Pages 1729-1740

  Li, Huangyuan ^a   Wu, Siying ^a   Wang, Zhangjing ^a   Lin, Wei ^a   Zhang, Chenzi ^a   Huang, Bin ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Heme oxygenase 1 (HO 1); Neurodegeneration; NF E2 related factor 2 (Nrf2); Paraquat; Tert butylhydroquinone (tBHQ)

Indexed keywords

HEME OXYGENASE 1; PARAQUAT; TERT BUTYLHYDROQUINONE; TRANSCRIPTION FACTOR NRF2; TYROSINE 3 MONOOXYGENASE;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL LEVEL; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVATION; IN VITRO STUDY; IN VIVO STUDY; LOCOMOTION; MALE; MOUSE; NERVE CELL DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PARKINSONISM; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; SUBSTANTIA NIGRA; TASK PERFORMANCE; TRANSCRIPTION INITIATION;

ANIMALS; APOPTOSIS; BASE SEQUENCE; DOPAMINERGIC NEURONS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEME OXYGENASE-1; HYDROQUINONES; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MOTOR ACTIVITY; NEURODEGENERATIVE DISEASES; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; PARAQUAT; PC12 CELLS; RATS; SUBSTANTIA NIGRA; TYROSINE 3-MONOOXYGENASE;

MUS;

EID: 84871212366     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-012-0935-y     Document Type: Article

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