메뉴 건너뛰기




Volumn 27, Issue 7, 2011, Pages 579-590

The pesticide deltamethrin increases free radical production and promotes nuclear translocation of the stress response transcription factor Nrf2 in rat brain

Author keywords

Deltamethrin; free radical; in vivo; neurotoxicity; Nrf2; oxidative stress

Indexed keywords

BETA ACTIN; DELTAMETHRIN; FREE RADICAL; HEME OXYGENASE 1; NEUROTOXIN; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2;

EID: 79960957451     PISSN: 07482337     EISSN: None     Source Type: Journal    
DOI: 10.1177/0748233710393400     Document Type: Article
Times cited : (45)

References (44)
  • 4
    • 26844537386 scopus 로고    scopus 로고
    • Increased nuclear factor-erythroid 2 p45-related factor 2 activity protects SH-SY5Y cells against oxidative damage
    • Cao TT, Ma L., Kandpal G., Warren L., Hess JF, and Seabrook GR (2005) Increased nuclear factor-erythroid 2 p45-related factor 2 activity protects SH-SY5Y cells against oxidative damage. Journal of Neurochemistry, 95: 406-417.
    • (2005) Journal of Neurochemistry , vol.95 , pp. 406-417
    • Cao, T.T.1    Ma, L.2    Kandpal, G.3    Warren, L.4    Hess, J.F.5    Seabrook, G.R.6
  • 7
    • 40049088820 scopus 로고    scopus 로고
    • The Nrf2-Keap1 defence pathway, Role in protection against drug-induced toxicity
    • Copple IM, Goldring CE, Kitteringham NR, and Park BK (2008) The Nrf2-Keap1 defence pathway, Role in protection against drug-induced toxicity. Toxicology, 246: 24-33.
    • (2008) Toxicology , vol.246 , pp. 24-33
    • Copple, I.M.1    Goldring, C.E.2    Kitteringham, N.R.3    Park, B.K.4
  • 9
    • 2442542312 scopus 로고    scopus 로고
    • PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress
    • Cullinan SB and Diehl JA (2004) PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress. Journal of Biological Chemistry, 279: 20108-20117.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 20108-20117
    • Cullinan, S.B.1    Diehl, J.A.2
  • 11
  • 12
    • 2442535969 scopus 로고    scopus 로고
    • Nitric oxide-induced transcriptional up-regulation of protective genes by Nrf2 via the antioxidant response element counteracts apoptosis of neuroblastoma cells
    • Dhakshinamoorthy S. and Porter AG (2004) Nitric oxide-induced transcriptional up-regulation of protective genes by Nrf2 via the antioxidant response element counteracts apoptosis of neuroblastoma cells. Journal of Biological Chemistry, 279: 20096-20107.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 20096-20107
    • Dhakshinamoorthy, S.1    Porter, A.G.2
  • 13
    • 0036371485 scopus 로고    scopus 로고
    • Roles of Nrf2 in activation of antioxidant enzyme genes via antioxidant responsive elements
    • Ishii T., Itoh K., and Yamamoto M. (2002) Roles of Nrf2 in activation of antioxidant enzyme genes via antioxidant responsive elements. Methods in Enzymology, 348: 182-190.
    • (2002) Methods in Enzymology , vol.348 , pp. 182-190
    • Ishii, T.1    Itoh, K.2    Yamamoto, M.3
  • 15
    • 0032805772 scopus 로고    scopus 로고
    • In vivo effects of deltamethrin on dopamine neurochemistry and the role of augmented neurotransmitter release
    • Kirby ML, Castagnoli K., and Bloomquist JR (1999) In vivo effects of deltamethrin on dopamine neurochemistry and the role of augmented neurotransmitter release. Pesticide Biochemistry and Physiology, 65: 160-168.
    • (1999) Pesticide Biochemistry and Physiology , vol.65 , pp. 160-168
    • Kirby, M.L.1    Castagnoli, K.2    Bloomquist, J.R.3
  • 16
    • 3543008924 scopus 로고    scopus 로고
    • Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2
    • Kobayashi A., Kang MI, Okawa H., Ohtsuji M., Zenke Y., Chiba T., et al. (2004) Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2. Molecular Cell Biology, 24,7130 -7139.
    • (2004) Molecular Cell Biology , vol.24 , pp. 7130-7139
    • Kobayashi, A.1    Kang, M.I.2    Okawa, H.3    Ohtsuji, M.4    Zenke, Y.5    Chiba, T.6
  • 17
    • 0037434737 scopus 로고    scopus 로고
    • Nrf2 is an inhibitor of the Fas pathway as identified by Achilles’ Heel Method, a new function-based approach to gene identification in human cells
    • Kotlo KU, Yehiely F., Efimova E., Harasty H., Hesabi B., Shchors K., et al. (2003) Nrf2 is an inhibitor of the Fas pathway as identified by Achilles’ Heel Method, a new function-based approach to gene identification in human cells. Oncogene, 22: 797-806.
    • (2003) Oncogene , vol.22 , pp. 797-806
    • Kotlo, K.U.1    Yehiely, F.2    Efimova, E.3    Harasty, H.4    Hesabi, B.5    Shchors, K.6
  • 18
    • 0842304134 scopus 로고    scopus 로고
    • Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult
    • Kraft AD, Johnson DA, and Johnson JA (2004) Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult. Journal of Neurosciences, 24: 1101-1112.
    • (2004) Journal of Neurosciences , vol.24 , pp. 1101-1112
    • Kraft, A.D.1    Johnson, D.A.2    Johnson, J.A.3
  • 19
    • 0038146898 scopus 로고    scopus 로고
    • Identification of the NF-E2-related factor-2dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis
    • Lee JM, Calkins MJ, Chan K., Kan YW, and Johnson JA (2003a) Identification of the NF-E2-related factor-2dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis. Journal of Biological Chemistry, 278: 12029-12038.
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 12029-12038
    • Lee, J.M.1    Calkins, M.J.2    Chan, K.3    Kan, Y.W.4    Johnson, J.A.5
  • 20
    • 0141621061 scopus 로고    scopus 로고
    • NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons
    • Lee JM, Shih AY, Murphy TH, and Johnson JA (2003b) NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons. Journal of Biological Chemistry, 278: 37948-37956.
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 37948-37956
    • Lee, J.M.1    Shih, A.Y.2    Murphy, T.H.3    Johnson, J.A.4
  • 22
    • 33748310792 scopus 로고    scopus 로고
    • Peroxynitrite induces HO-1 expression via PI3K/Akt-dependent activation of NF-E2-related factor 2 in PC12 cells
    • Li MH, Cha YN, and Surh YJ (2006a) Peroxynitrite induces HO-1 expression via PI3K/Akt-dependent activation of NF-E2-related factor 2 in PC12 cells. Free Radical Biology and Medicine, 41: 1079- 1091.
    • (2006) Free Radical Biology and Medicine , vol.41 , pp. 1079-1091
    • Li, M.H.1    Cha, Y.N.2    Surh, Y.J.3
  • 23
    • 79960946685 scopus 로고    scopus 로고
    • Effects of deltamethrin on the activation or expression of Nrf2 and on the GCS-HS protein level in primary astrocytes with laser scanning confocal microscope
    • Li HY, Shi N., Zhong YF, and Liu LL (2006b) Effects of deltamethrin on the activation or expression of Nrf2 and on the GCS-HS protein level in primary astrocytes with laser scanning confocal microscope. Journal of Nanjing Medical University, 20: 1-7.
    • (2006) Journal of Nanjing Medical University , vol.20 , pp. 1-7
    • Li, H.Y.1    Shi, N.2    Zhong, Y.F.3    Liu, L.L.4
  • 24
    • 35148835788 scopus 로고    scopus 로고
    • NF-E2 related factor 2 activation and Heme oxygenase-1 induction by tert-butylhydroquinone protect against deltamethrin mediated oxidative stress in PC12 cells
    • Li HY, Zhong YF, Wu SY, and Shi N. (2007a) NF-E2 related factor 2 activation and Heme oxygenase-1 induction by tert-butylhydroquinone protect against deltamethrin mediated oxidative stress in PC12 cells. Chemical Research in Toxicology, 20: 1242-1251.
    • (2007) Chemical Research in Toxicology , vol.20 , pp. 1242-1251
    • Li, H.Y.1    Zhong, Y.F.2    Wu, S.Y.3    Shi, N.4
  • 25
    • 34347273429 scopus 로고    scopus 로고
    • Transcription factor Nrf2 activation by deltamethrin in PC12 cells: involvement of ROS
    • Li HY, Wu SY, and Shi N. (2007b) Transcription factor Nrf2 activation by deltamethrin in PC12 cells: involvement of ROS. Toxicology Letters, 171: 87-98.
    • (2007) Toxicology Letters , vol.171 , pp. 87-98
    • Li, H.Y.1    Wu, S.Y.2    Shi, N.3
  • 26
    • 4344688670 scopus 로고    scopus 로고
    • Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals
    • Li N., Alam J., Venkatesan MI, Eiguren-Fernandez A., Schmitz D., Di Stefano, et al. (2004) Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals. Journal of Immunology, 173: 3467-3481.
    • (2004) Journal of Immunology , vol.173 , pp. 3467-3481
    • Li, N.1    Alam, J.2    Venkatesan, M.I.3    Eiguren-Fernandez, A.4    Schmitz, D.5    Di Stefano6
  • 27
    • 31344467317 scopus 로고    scopus 로고
    • The inhibitory effects of deltamethrin on dopamine biosynthesis in rat PC12 cells
    • Liu GP and Shi N. (2006a) The inhibitory effects of deltamethrin on dopamine biosynthesis in rat PC12 cells. Toxicology Letters, 161: 195-199.
    • (2006) Toxicology Letters , vol.161 , pp. 195-199
    • Liu, G.P.1    Shi, N.2
  • 28
    • 33646002364 scopus 로고    scopus 로고
    • Tyrosine hydroxylase as a target for deltamethrin in the nigrostriatal dopaminergic pathway
    • Liu GP, Ma Q., and Shi N. (2006b) Tyrosine hydroxylase as a target for deltamethrin in the nigrostriatal dopaminergic pathway. Biochemical Envrionmental Science, 19: 27-34.
    • (2006) Biochemical Envrionmental Science , vol.19 , pp. 27-34
    • Liu, G.P.1    Ma, Q.2    Shi, N.3
  • 29
    • 1542335553 scopus 로고    scopus 로고
    • Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol
    • Martin D., Rojo AI, Salinas M., Diaz R., Gallardo G., Alam J., De Galarreta CM, and Cuadrado A. (2004) Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol. Journal of Biological Chemistry, 279: 8919-8929.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 8919-8929
    • Martin, D.1    Rojo, A.I.2    Salinas, M.3    Diaz, R.4    Gallardo, G.5    Alam, J.6    De Galarreta, C.M.7    Cuadrado, A.8
  • 31
    • 0028061444 scopus 로고
    • Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region
    • Moi P., Chan K., Asunis I., Cao A., and Kan YW (1994) Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region. Proceedings of the National Academy of Sciences USA, 91: 9926-9930.
    • (1994) Proceedings of the National Academy of Sciences USA , vol.91 , pp. 9926-9930
    • Moi, P.1    Chan, K.2    Asunis, I.3    Cao, A.4    Kan, Y.W.5
  • 32
    • 0037763721 scopus 로고    scopus 로고
    • Regulatory mechanisms controlling gene expression mediated by the antioxidant response element
    • Nguyen T., Sherratt PJ, and Pickett CB (2003) Regulatory mechanisms controlling gene expression mediated by the antioxidant response element. Annual Review of Pharmacology and Toxicology, 43: 233-260.
    • (2003) Annual Review of Pharmacology and Toxicology , vol.43 , pp. 233-260
    • Nguyen, T.1    Sherratt, P.J.2    Pickett, C.B.3
  • 33
    • 3142570440 scopus 로고    scopus 로고
    • The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress
    • Nguyen T., Yang CS, and Pickett CB (2004) The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress. Free Radical Biology and Medicine, 37,433- 441.
    • (2004) Free Radical Biology and Medicine , vol.37 , pp. 433-441
    • Nguyen, T.1    Yang, C.S.2    Pickett, C.B.3
  • 34
    • 84865344407 scopus 로고    scopus 로고
    • Effect of deltamethrin on the activity of nitric oxide synthase in the central nervous system of rat
    • Niu Y., Shi N., Wu A., Yan H., and Liu YG (1997) Effect of deltamethrin on the activity of nitric oxide synthase in the central nervous system of rat. Journal of Health and Toxicology, 11: 75-77.
    • (1997) Journal of Health and Toxicology , vol.11 , pp. 75-77
    • Niu, Y.1    Shi, N.2    Wu, A.3    Yan, H.4    Liu, Y.G.5
  • 35
    • 0032829602 scopus 로고    scopus 로고
    • Identification of NRF2, a member of the NF-E2 family of transcription factors, as a substrate for caspase-3(-like) proteases
    • Ohtsubo T., Kamada S., Mikami T., Murakami H., and Tsujimoto Y. (1999) Identification of NRF2, a member of the NF-E2 family of transcription factors, as a substrate for caspase-3(-like) proteases. Cell Death and Differentiation, 6: 6865-6872.
    • (1999) Cell Death and Differentiation , vol.6 , pp. 6865-6872
    • Ohtsubo, T.1    Kamada, S.2    Mikami, T.3    Murakami, H.4    Tsujimoto, Y.5
  • 36
    • 37149039327 scopus 로고    scopus 로고
    • Investigation of the effect of a panel of model hepatotoxins on the Nrf2-Keap1 defence response pathway in CD-1 mice
    • Randle LE, Goldring CEP, Benson CA, Metcalfe PN, Kitteringham NR, et al. (2008) Investigation of the effect of a panel of model hepatotoxins on the Nrf2-Keap1 defence response pathway in CD-1 mice. Toxicology, 243: 249-260.
    • (2008) Toxicology , vol.243 , pp. 249-260
    • Randle, L.E.1    Goldring, C.E.P.2    Benson, C.A.3    Metcalfe, P.N.4    Kitteringham, N.R.5
  • 37
    • 49749117926 scopus 로고    scopus 로고
    • Functional interference between glycogen synthase kinase-3 beta and the transcription factor Nrf2 in protection against kainate-induced hippocampal cell death
    • Rojo AI, Rada P., Egea J., Rosa AO, López MG, and Cuadrado A. (2008) Functional interference between glycogen synthase kinase-3 beta and the transcription factor Nrf2 in protection against kainate-induced hippocampal cell death. Molecular and Cellular Neuroscience, 39: 125-132.
    • (2008) Molecular and Cellular Neuroscience , vol.39 , pp. 125-132
    • Rojo, A.I.1    Rada, P.2    Egea, J.3    Rosa, A.O.4    López, M.G.5    Cuadrado, A.6
  • 38
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins with ‘mini-extracts’, prepared from a small number of cells
    • Schreiber E., Matthias P., Mūller MM, and Schaffner W. (1989) Rapid detection of octamer binding proteins with ‘mini-extracts’, prepared from a small number of cells. Nucleic Acids Research, 17: 6419.
    • (1989) Nucleic Acids Research , vol.17 , pp. 6419
    • Schreiber, E.1    Matthias, P.2    Mūller, M.M.3    Schaffner, W.4
  • 39
    • 0029892645 scopus 로고    scopus 로고
    • Detection of elevated reactive oxygen species level in cultured rat hepatocytes treated with aflatoxin B1
    • Shen HM, Shi CY, Shen Y., Shen Y., and Ong CN (1996) Detection of elevated reactive oxygen species level in cultured rat hepatocytes treated with aflatoxin B1. Free Radical Biology and Medicine, 21: 139-146.
    • (1996) Free Radical Biology and Medicine , vol.21 , pp. 139-146
    • Shen, H.M.1    Shi, C.Y.2    Shen, Y.3    Shen, Y.4    Ong, C.N.5
  • 40
    • 0037996661 scopus 로고    scopus 로고
    • Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress
    • Shih AY, Johnson DA, Wong G., Kraft AD, Jiang L., Erb H., et al. (2003) Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress. Journal Neuroscience, 23: 3394-3406.
    • (2003) Journal Neuroscience , vol.23 , pp. 3394-3406
    • Shih, A.Y.1    Johnson, D.A.2    Wong, G.3    Kraft, A.D.4    Jiang, L.5    Erb, H.6
  • 42
    • 0033979159 scopus 로고    scopus 로고
    • Apoptotic cell death in rat brain following deltamethrin treatment
    • Wu AG and Liu YG (2000a) Apoptotic cell death in rat brain following deltamethrin treatment. Neuroscience Letters, 279: 85-88.
    • (2000) Neuroscience Letters , vol.279 , pp. 85-88
    • Wu, A.G.1    Liu, Y.G.2
  • 43
    • 0033928213 scopus 로고    scopus 로고
    • Deltamethrin induces delayed apoptosis and altered expression of p53 and bax in rat brain
    • Wu AG and Liu YG (2000b) Deltamethrin induces delayed apoptosis and altered expression of p53 and bax in rat brain. Environmental and Toxicology and Pharmacology, 8: 183-189.
    • (2000) Environmental and Toxicology and Pharmacology , vol.8 , pp. 183-189
    • Wu, A.G.1    Liu, Y.G.2
  • 44
    • 0034697373 scopus 로고    scopus 로고
    • Deltamethrin induces altered expression of P53, Bax and Bcl-2 in rat brain
    • Wu AG, Hu QS, Ren TL, and Liu YG (2000) Deltamethrin induces altered expression of P53, Bax and Bcl-2 in rat brain. Neuroscience Letters, 284: 29-32.
    • (2000) Neuroscience Letters , vol.284 , pp. 29-32
    • Wu, A.G.1    Hu, Q.S.2    Ren, T.L.3    Liu, Y.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.