Phosphorylation of PNKP by ATM prevents its proteasomal degradation and enhances resistance to oxidative stress

Nucleic Acids Research

Volumn 40, Issue 22, 2012, Pages 11404-11415

  Parsons, Jason L ^a   Khoronenkova, Svetlana V ^a   Dianova, Irina I ^a   Ternette, Nicola ^b   Kessler, Benedikt M ^b   Datta, Pran K ^c   Dianov, Grigory L ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; PHOSPHATASE; POLYNUCLEOTIDE KINASE PHOSPHATASE; PROTEIN SERINE THREONINE KINASE; SERINE; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE CUL4A; UBIQUITIN PROTEIN LIGASE DDB1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL LEVEL; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; EMBRYO; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME PURIFICATION; ENZYME REGULATION; ENZYME SPECIFICITY; ENZYME STABILITY; ENZYME SUBSTRATE COMPLEX; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; STEADY STATE; UBIQUITINATION;

ANIMALS; CARRIER PROTEINS; CELL CYCLE PROTEINS; CULLIN PROTEINS; DNA DAMAGE; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; ENZYME STABILITY; HELA CELLS; HUMANS; MICE; OXIDATIVE STRESS; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84871184872     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gks909     Document Type: Article

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