Cholesterol and sphingomyelin drive ligand-independent T-cell antigen receptor nanoclustering

Journal of Biological Chemistry

Volumn 287, Issue 51, 2012, Pages 42664-42674

  Molnár, Eszter ^a,b,i   Swamy, Mahima ^a,b,i   Holzer, Martin ^b   Beck García, Katharina ^a,b   Worch, Remigiusz ^c,j   Thiele, Christoph ^d   Guigas, Gernot ^e   Boye, Kristian ^f   Luescher, Immanuel F ^g   Schwille, Petra ^c   Schubert, Rolf ^b   Schamel, Wolfgang W A ^a,b,h  

^a MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^d UNIVERSITY OF BONN   (Germany)

^e UNIVERSITY OF BAYREUTH   (Germany)

^f GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^g LUDWIG INSTITUTE FOR CANCER RESEARCH   (Switzerland)

^h UNIVERSITY OF FREIBURG   (Germany)

ⁱ KING'S COLLEGE LONDON   (United Kingdom)

^j INSTITUTE OF PHYSICS   (Poland)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN BINDING; CELLULAR MEMBRANES; DISORDERED PHASE; ENHANCED SENSITIVITY; GIANT UNILAMELLAR VESICLES; IN-VIVO; LARGE UNILAMELLAR VESICLES; LIPID COMPOSITION; PROTEIN INTERACTION; SPHINGOMYELIN; SYNTHETIC BIOLOGY; T CELLS; T-CELL ANTIGEN RECEPTORS;

ANTIGENS; CELL MEMBRANES; CHOLESTEROL; DIMERS; LIPOSOMES; PHOSPHOLIPIDS;

CYTOLOGY;

CHOLESTEROL; LIPOSOME; MEMBRANE LIPID; PHOSPHATIDYLCHOLINE; SPHINGOMYELIN; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ARTICLE; CONTROLLED STUDY; DIMERIZATION; HUMAN; HUMAN CELL; IN VIVO STUDY; LIGAND BINDING; LIPID COMPOSITION; LIPID MEMBRANE; MOLECULAR INTERACTION; NANOANALYSIS; NANOCHEMISTRY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RECEPTOR AFFINITY; SENSITIVITY ANALYSIS;

ANIMALS; CELL MEMBRANE; CELL SURVIVAL; CHOLESTEROL; CLUSTER ANALYSIS; CROSS-LINKING REAGENTS; HISTOCOMPATIBILITY ANTIGENS; HUMANS; LIGANDS; MICE; NANOPARTICLES; PEPTIDES; PHOSPHATIDYLCHOLINES; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN SUBUNITS; RECEPTORS, ANTIGEN, B-CELL; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, TRANSFERRIN; SPHINGOMYELINS; UNILAMELLAR LIPOSOMES;

PHOS;

EID: 84871125392     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.386045     Document Type: Article

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