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Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 1, 2013, Pages 132-137

Synthesis and evaluation of novel ligands for the histamine H4 receptor based on a pyrrolo[2,3-d]pyrimidine scaffold

(6) Gao, Ling Jie a Schwed, J Stephan b Weizel, Lilia b De Jonghe, Steven a Stark, Holger b Herdewijn, Piet a

a REGA INSTITUTE FOR MEDICAL RESEARCH (Belgium)

b GOETHE UNIVERSITY (Germany)

Author keywords

Histamine 4 receptor; Pyrimidine; Pyrrolo 2,3 d pyrimidine

Indexed keywords

1 (5 CHLORO 2 INDOLYLCARBONYL) 4 METHYLPIPERAZINE; 2 AMINO 4 N PIPERAZINYL 6 METHYL PYRROLO[2,3 D]PYRIMIDINE; 2,6 DIAMINO 4 (N METHYL PIPERAZIN 1 YL)PYRIMIDINE; 6 (4 FLUOROPHENYL)PYRROLO[2,3 D]PYRIMIDINE; 6 PHENYL PYRROLO[2,3 D]PYRIMIDINE; BENZO[6,7]CYCLOHEPTA[1,2 D]PYRIMIDINE; BENZOFURO[3,2 D]PYRIMIDINE; BENZOTHIENOL[3,2 D]PYRIMIDINE; FURO[3,2 D]PYRIMIDINE; HISTAMINE H4 RECEPTOR; HISTAMINE H4 RECEPTOR ANTAGONIST; LIGAND; PURINE; PYRAZOLO[4,3 D]PYRIMIDINE; PYRROLO[2,3 D]PYRIMIDINE DERIVATIVE; QUINAZOLINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL;

HUMANS; LIGANDS; PROTEIN BINDING; PYRIMIDINES; PYRROLES; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84870987858 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.10.139 Document Type: Article

Times cited : (16)

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