-
1
-
-
0034670162
-
Inhibition of cellular action of thrombin by N3-cyclopropyl-7-[[4-(1-methylethyl)phenyl]methyl]-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine (SCH 79797), a nonpeptide thrombin receptorantagonist
-
Ahn, H. S., Foster, C., Boykow, G., Stamford, A., Manna, M., and Graziano, M. (2000). Inhibition of cellular action of thrombin by N3-cyclopropyl-7-[[4-(1-methylethyl)phenyl]methyl]-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine (SCH 79797), a nonpeptide thrombin receptorantagonist. Biochem. Pharmacol. 60, 1425-1434
-
(2000)
Biochem. Pharmacol.
, vol.60
, pp. 1425-1434
-
-
Ahn, H.S.1
Foster, C.2
Boykow, G.3
Stamford, A.4
Manna, M.5
Graziano, M.6
-
2
-
-
0028825940
-
Detection of functional receptors for the proteinase-activated-receptor-2-activating polypeptide, SLIGRL-NH2, in rat vascular and gastric smooth muscle
-
Al Ani, B., Saifeddine, M., and Hol-lenberg, M. D. (1995). Detection of functional receptors for the proteinase-activated-receptor-2-activating polypeptide, SLIGRL-NH2, in rat vascular and gastric smooth muscle. Can. J. Physiol. Pharmacol. 73, 1203-1207.
-
(1995)
Can. J. Physiol. Pharmacol.
, vol.73
, pp. 1203-1207
-
-
Al Ani, B.1
Saifeddine, M.2
Hol-lenberg, M.D.3
-
3
-
-
66049093837
-
Fecal proteases from diarrheic-IBS and ulcerative colitis patients exert opposite effect on visceral sensitivity in mice
-
Annahazi, A., Gecse, K., Dabek, M., Ait-Belgnaoui, A., Rosztoczy, A., Roka, R., Molnar, T., Theodorou, V., Wittmann, T., Bueno, L., and Eutamene, H. (2009). Fecal proteases from diarrheic-IBS and ulcerative colitis patients exert opposite effect on visceral sensitivity in mice. Pain 144, 209-217.
-
(2009)
Pain
, vol.144
, pp. 209-217
-
-
Annahazi, A.1
Gecse, K.2
Dabek, M.3
Ait-Belgnaoui, A.4
Rosztoczy, A.5
Roka, R.6
Molnar, T.7
Theodorou, V.8
Wittmann, T.9
Bueno, L.10
Eutamene, H.11
-
4
-
-
10744225624
-
Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome
-
Barbara, G., Stanghellini, V., De Giorgio, R., Cremon, C., Cottrell, G. S., Santini, D., Pasquinelli, G., Morselli-Labate, A. M., Grady, E. F., Bun-nett, N. W., Collins, S. M., and Cori-naldesi, R. (2004). Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome. Gastroen-terology 126, 693-702.
-
(2004)
Gastroen-terology
, vol.126
, pp. 693-702
-
-
Barbara, G.1
Stanghellini, V.2
De Giorgio, R.3
Cremon, C.4
Cottrell, G.S.5
Santini, D.6
Pasquinelli, G.7
Morselli-Labate, A.M.8
Grady, E.F.9
Bun-nett, N.W.10
Collins, S.M.11
Cori-naldesi, R.12
-
5
-
-
33846193703
-
Mast cell-dependent excitation of visceral-nociceptive sensory neurons in irritable bowel syndrome
-
Barbara, G., Wang, B., Stanghellini, V., De Giorgio, R., Cremon, C., Di Nardo, G., Trevisani, M., Campi, B., Geppetti, P., Tonini, M., Bunnett, N. W., Grundy, D., and Corinaldesi, R. (2007). Mast cell-dependent excitation of visceral-nociceptive sensory neurons in irritable bowel syndrome. Gastroenterology 132, 26-37.
-
(2007)
Gastroenterology
, vol.132
, pp. 26-37
-
-
Barbara, G.1
Wang, B.2
Stanghellini, V.3
De Giorgio, R.4
Cremon, C.5
Di Nardo, G.6
Trevisani, M.7
Campi, B.8
Geppetti, P.9
Tonini, M.10
Bunnett, N.W.11
Grundy, D.12
Corinaldesi, R.13
-
6
-
-
34548319667
-
Histamine excites neurones in the human submucous plexus through activation of H1, H2
-
Breunig, E., Michel, K., Zeller, F., Seidl, S., Weyhern, C. W., and Schemann, M. (2007). Histamine excites neurones in the human submucous plexus through activation of H1, H2, H3 and H4 receptors. J. Physiol. (Lond.) 583, 731-742.
-
(2007)
H3 and H4 receptors. J. Physiol. (Lond.)
, vol.583
, pp. 731-742
-
-
Breunig, E.1
Michel, K.2
Zeller, F.3
Seidl, S.4
Weyhern, C.W.5
Schemann, M.6
-
7
-
-
70349423402
-
Activation of human enteric neurons by super-natants of colonic biopsy specimens from patients with irritable bowel syndrome
-
Buhner, S., Li, Q., Vignali, S., Barbara, G., De Giorgio, R., Stanghellini, V., Cremon, C., Zeller, F., Langer, R., Daniel, H., Michel, K., and Sche-mann, M. (2009). Activation of human enteric neurons by super-natants of colonic biopsy specimens from patients with irritable bowel syndrome. Gastroenterology 137, 1425-1434.
-
(2009)
Gastroenterology
, vol.137
, pp. 1425-1434
-
-
Buhner, S.1
Li, Q.2
Vignali, S.3
Barbara, G.4
De Giorgio, R.5
Stanghellini, V.6
Cremon, C.7
Zeller, F.8
Langer, R.9
Daniel, H.10
Michel, K.11
Sche-mann, M.12
-
8
-
-
82955163063
-
Mast cell-nerve axis with a focus on the human gut
-
Buhner, S., and Schemann, M. (2012). Mast cell-nerve axis with a focus on the human gut. Biochim. Biophys. Acta 1822, 85-92.
-
(2012)
Biochim. Biophys. Acta
, vol.1822
, pp. 85-92
-
-
Buhner, S.1
Schemann, M.2
-
9
-
-
0034890077
-
Protease-activated receptor-1 stimulates Ca(2+)-dependent Cl(-) secretion in human intestinal epithelial cells
-
Buresi, M. C., Schleihauf, E., Vergnolle, N., Buret, A., Wallace, J. L., Hol-lenberg, M. D., and MacNaughton, W. K. (2001). Protease-activated receptor-1 stimulates Ca(2+)-dependent Cl(-) secretion in human intestinal epithelial cells. Am. J. Physiol. Gastrointest. Liver Physiol. 281, G323-G332.
-
(2001)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.281
-
-
Buresi, M.C.1
Schleihauf, E.2
Vergnolle, N.3
Buret, A.4
Wallace, J.L.5
Hol-lenberg, M.D.6
MacNaughton, W.K.7
-
10
-
-
0031613754
-
Colonic proteinases: increased activity in patients with ulcerative colitis
-
Bustos, D., Negri, G., De Paula, J. A., Di Carlo, M., Yapur, V., Facente, A., and De Paula, A. (1998). Colonic proteinases: increased activity in patients with ulcerative colitis. Med-icina (B Aires) 58, 262-264.
-
(1998)
Med-icina (B Aires)
, vol.58
, pp. 262-264
-
-
Bustos, D.1
Negri, G.2
De Paula, J.A.3
Di Carlo, M.4
Yapur, V.5
Facente, A.6
De Paula, A.7
-
11
-
-
33847342529
-
Role for protease activity in visceral pain in irritable bowel syndrome
-
Cenac, N., Andrews, C. N., Holzhausen, M., Chapman, K., Cottrell, G., Andrade-Gordon, P., Steinhoff, M., Barbara, G., Beck, P., Bunnett, N. W., Sharkey, K. A., Ferraz, J. G., Shaffer, E., and Vergnolle, N. (2007). Role for protease activity in visceral pain in irritable bowel syndrome. J. Clin. Invest. 117, 636-647.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 636-647
-
-
Cenac, N.1
Andrews, C.N.2
Holzhausen, M.3
Chapman, K.4
Cottrell, G.5
Andrade-Gordon, P.6
Steinhoff, M.7
Barbara, G.8
Beck, P.9
Bunnett, N.W.10
Sharkey, K.A.11
Ferraz, J.G.12
Shaffer, E.13
Vergnolle, N.14
-
12
-
-
0036840275
-
Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2
-
Cenac, N., Coelho, A. M., Nguyen, C., Compton, S., Andrade-Gordon, P., MacNaughton, W. K., Wallace, J. L., Hollenberg, M. D., Bunnett, N. W., Garcia-Villar, R., Bueno, L., and Vergnolle, N. (2002). Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2. Am. J. Pathol. 161, 1903-1915.
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 1903-1915
-
-
Cenac, N.1
Coelho, A.M.2
Nguyen, C.3
Compton, S.4
Andrade-Gordon, P.5
MacNaughton, W.K.6
Wallace, J.L.7
Hollenberg, M.D.8
Bunnett, N.W.9
Garcia-Villar, R.10
Bueno, L.11
Vergnolle, N.12
-
13
-
-
0141816690
-
Differential expression and regulation of protease-activated receptors in human peripheral mono-cytes and monocyte-derived antigen-presenting cells
-
Colognato, R., Slupsky, J. R., Jen-drach, M., Burysek, L., Syrovets,T., and Simmet, T. (2003). Differential expression and regulation of protease-activated receptors in human peripheral mono-cytes and monocyte-derived antigen-presenting cells. Blood 102, 2645-2652.
-
(2003)
Blood
, vol.102
, pp. 2645-2652
-
-
Colognato, R.1
Slupsky, J.R.2
Jen-drach, M.3
Burysek, L.4
Syrovets, T.5
Simmet, T.6
-
14
-
-
0345004978
-
Thrombin and mast cell tryptase regulate guinea-pig myenteric neurons through proteinase-activated receptors-1 and -2
-
Corvera, C. U., Dery, O., McCona-logue, K., Gamp, P., Thoma, M., Al Ani, B., Caughey, G. H., Hollenberg, M. D., and Bunnett, N. W. (1999). Thrombin and mast cell tryptase regulate guinea-pig myenteric neurons through proteinase-activated receptors-1 and -2.J. Physiol. (Lond.) 517, 741-756.
-
(1999)
J. Physiol. (Lond.)
, vol.517
, pp. 741-756
-
-
Corvera, C.U.1
Dery, O.2
McCona-logue, K.3
Gamp, P.4
Thoma, M.5
Al Ani, B.6
Caughey, G.H.7
Hollenberg, M.D.8
Bunnett, N.W.9
-
15
-
-
0036828264
-
Serine proteases excite myenteric neurons through protease-activated receptors in guinea pig small intestine
-
Gao, C., Liu, S., Hu, H. Z., Gao, N., Kim, G. Y., Xia, Y., and Wood, J. D. (2002). Serine proteases excite myenteric neurons through protease-activated receptors in guinea pig small intestine. Gastroenterology 123, 1554-1564.
-
(2002)
Gastroenterology
, vol.123
, pp. 1554-1564
-
-
Gao, C.1
Liu, S.2
Hu, H.Z.3
Gao, N.4
Kim, G.Y.5
Xia, Y.6
Wood, J.D.7
-
16
-
-
0036830286
-
Presence of functionally active protease-activated receptors 1 and 2 in myen-teric glia
-
Garrido, R., Segura, B., Zhang, W., and Mulholland, M. (2002). Presence of functionally active protease-activated receptors 1 and 2 in myen-teric glia. J. Neurochem. 83, 556-564.
-
(2002)
J. Neurochem.
, vol.83
, pp. 556-564
-
-
Garrido, R.1
Segura, B.2
Zhang, W.3
Mulholland, M.4
-
17
-
-
77951863416
-
Getting the message across: pathophysiol-ogy and signaling via receptors for polypeptide hormones and pro-teinases
-
Hollenberg, M. D. (2010). Getting the message across: pathophysiol-ogy and signaling via receptors for polypeptide hormones and pro-teinases. Clin. Invest. Med. 33, E133.
-
(2010)
Clin. Invest. Med.
, vol.33
-
-
Hollenberg, M.D.1
-
19
-
-
47549113638
-
Kallikreins and proteinase-mediated signaling: proteinase-activated receptors (PARs) and the pathophysiology of inflammatory diseases and cancer
-
Hollenberg, M. D., Oikonomopoulou, K., Hansen, K. K., Saifeddine, M., Ramachandran, R., and Dia-mandis, E. P. (2008). Kallikreins and proteinase-mediated signaling: proteinase-activated receptors (PARs) and the pathophysiology of inflammatory diseases and cancer. Biol. Chem. 389, 643-651.
-
(2008)
Biol. Chem.
, vol.389
, pp. 643-651
-
-
Hollenberg, M.D.1
Oikonomopoulou, K.2
Hansen, K.K.3
Saifeddine, M.4
Ramachandran, R.5
Dia-mandis, E.P.6
-
20
-
-
0030979972
-
Protease-activated receptor 3 is a second thrombin receptor in humans
-
Ishihara, H., Connolly, A. J., Zeng, D., Kahn,M. L., Zheng,Y.W., Timmons, C., Tram, T., and Coughlin, S. R. (1997). Protease-activated receptor 3 is a second thrombin receptor in humans. Nature 386, 502-506.
-
(1997)
Nature
, vol.386
, pp. 502-506
-
-
Ishihara, H.1
Connolly, A.J.2
Zeng, D.3
Kahn, M.L.4
Zheng, Y.W.5
Timmons, C.6
Tram, T.7
Coughlin, S.R.8
-
21
-
-
0032483456
-
Gene and locus structure and chromosomal localization of the protease-activated receptor gene family
-
Kahn, M. L., Hammes, S. R., Botka, C., and Coughlin, S. R. (1998). Gene and locus structure and chromosomal localization of the protease-activated receptor gene family. J. Biol. Chem. 273, 23290-23296.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 23290-23296
-
-
Kahn, M.L.1
Hammes, S.R.2
Botka, C.3
Coughlin, S.R.4
-
22
-
-
40349089742
-
Gastrointestinal roles for proteinase-activated receptors in health and disease
-
Kawabata, A., Matsunami, M., and Sekiguchi, F. (2008). Gastrointestinal roles for proteinase-activated receptors in health and disease. Br. J. Pharmacol. 153(Suppl. 1), S230- S240.
-
(2008)
Br. J. Pharmacol.
, vol.153
, Issue.SUPPL. 1
-
-
Kawabata, A.1
Matsunami, M.2
Sekiguchi, F.3
-
23
-
-
9144246209
-
A protective role of protease-activated receptor 1 in rat gastric mucosa
-
Kawabata, A., Nishikawa, H., Saitoh, H., Nakaya, Y., Hiramatsu, K., Kubo, S., Nishida, M., Kawao, N., Kuroda, R.,Sekiguchi, F., Kinoshita, M., Kakehi, K., Arizono, N., Yamagishi, H., and Kawai, K. (2004). A protective role of protease-activated receptor 1 in rat gastric mucosa. Gastroenterology 126, 208-219.
-
(2004)
Gastroenterology
, vol.126
, pp. 208-219
-
-
Kawabata, A.1
Nishikawa, H.2
Saitoh, H.3
Nakaya, Y.4
Hiramatsu, K.5
Kubo, S.6
Nishida, M.7
Kawao, N.8
Kuroda, R.9
Sekiguchi, F.10
Kinoshita, M.11
Kakehi, K.12
Arizono, N.13
Yamagishi, H.14
Kawai, K.15
-
24
-
-
49049086355
-
Mature dendritic cells express functional thrombin receptors triggering chemotaxis and CCL18/pulmonary and activation-regulated chemokine induction
-
Li, X., Syrovets, T., Paskas, S., Lau-monnier, Y., and Simmet, T. (2008). Mature dendritic cells express functional thrombin receptors triggering chemotaxis and CCL18/pulmonary and activation-regulated chemokine induction. J. Immunol. 181, 1215-1223.
-
(2008)
J. Immunol.
, vol.181
, pp. 1215-1223
-
-
Li, X.1
Syrovets, T.2
Paskas, S.3
Lau-monnier, Y.4
Simmet, T.5
-
25
-
-
0035941170
-
Agonists of proteinase-activated receptor 2 excite guinea pig ilealmyen-teric neurons
-
Linden, D. R., Manning, B. P., Bunnett, N.W.,and Mawe,G.M.(2001). Agonists of proteinase-activated receptor 2 excite guinea pig ilealmyen-teric neurons. Eur. J. Pharmacol. 431, 311-314.
-
(2001)
Eur. J. Pharmacol.
, vol.431
, pp. 311-314
-
-
Linden, D.R.1
Manning, B.P.2
Bunnett, N.W.3
Mawe, G.M.4
-
26
-
-
0036080438
-
Activation of ion secretion via proteinase-activated receptor-2 in human colon
-
Mall, M., Gonska, T., Thomas, J., Hirtz, S.,Schreiber,R.,andKunzelmann,K. (2002). Activation of ion secretion via proteinase-activated receptor-2 in human colon. Am. J. Physiol. Gas-trointest. Liver Physiol. 282, G200-G210.
-
(2002)
Am. J. Physiol. Gas-trointest. Liver Physiol.
, vol.282
-
-
Mall, M.1
Gonska, T.2
Thomas, J.3
Hirtz, S.4
Schreiber, R.5
Kunzelmann, K.6
-
27
-
-
0029670360
-
Thrombin and trypsin-induced Ca(2+) mobilization in human T cell lines through interaction with different protease-activated receptors
-
Mari, B., Guerin, S., Far, D. F., Bre-itmayer, J. P., Belhacene, N., Pey-ron, J. F., Rossi, B., and Auberger, P. (1996). Thrombin and trypsin-induced Ca(2+) mobilization in human T cell lines through interaction with different protease-activated receptors. FASEB J. 10, 309-316.
-
(1996)
FASEB J
, vol.10
, pp. 309-316
-
-
Mari, B.1
Guerin, S.2
Far, D.F.3
Bre-itmayer, J.P.4
Belhacene, N.5
Pey-ron, J.F.6
Rossi, B.7
Auberger, P.8
-
28
-
-
83455259766
-
Fast calcium and voltage sensitive dye imaging in enteric neurons reveal calcium peaks associated with single action potential discharge
-
Michel, K., Michaelis, M., Mazzuoli, G., Mueller, K., Vanden Berghe, P., and Schemann, M. (2011). Fast calcium and voltage sensitive dye imaging in enteric neurons reveal calcium peaks associated with single action potential discharge. J. Physiol. 589, 5941-5947.
-
(2011)
J. Physiol.
, vol.589
, pp. 5941-5947
-
-
Michel, K.1
Michaelis, M.2
Mazzuoli, G.3
Mueller, K.4
Vanden Berghe, P.5
Schemann, M.6
-
29
-
-
19044363544
-
Serotonin excites neurons in the human sub-mucous plexus via 5-HT3 receptors
-
Michel, K., Zeller, F., Langer, R., Nekarda, H., Kruger, D., Dover, T. J., Brady, C. A., Barnes, N. M., and Schemann, M. (2005). Serotonin excites neurons in the human sub-mucous plexus via 5-HT3 receptors. Gastroenterology 128, 1317-1326.
-
(2005)
Gastroenterology
, vol.128
, pp. 1317-1326
-
-
Michel, K.1
Zeller, F.2
Langer, R.3
Nekarda, H.4
Kruger, D.5
Dover, T.J.6
Brady, C.A.7
Barnes, N.M.8
Schemann, M.9
-
30
-
-
81855185567
-
Activity of protease-activated receptors in the human submucous plexus
-
Mueller, K., Michel, K., Krueger, D., Demir, I. E., Ceyhan, G. O., Zeller, F., Kreis, M. E., and Schemann, M. (2011). Activity of protease-activated receptors in the human submucous plexus. Gastroenterology 141, 2088-2097.
-
(2011)
Gastroenterology
, vol.141
, pp. 2088-2097
-
-
Mueller, K.1
Michel, K.2
Krueger, D.3
Demir, I.E.4
Ceyhan, G.O.5
Zeller, F.6
Kreis, M.E.7
Schemann, M.8
-
31
-
-
0032841773
-
Multisite optical recording of excitability in the enteric nervous system
-
Neunlist, M., Peters, S., and Schemann, M. (1999). Multisite optical recording of excitability in the enteric nervous system. Neurogastroenterol. Motil. 11, 393-402.
-
(1999)
Neurogastroenterol. Motil.
, vol.11
, pp. 393-402
-
-
Neunlist, M.1
Peters, S.2
Schemann, M.3
-
32
-
-
0029113121
-
Molecular cloning and functional expression of the gene encoding the human proteinase-activatedreceptor 2
-
Nystedt, S., Emilsson, K., Larsson, A. K., Strombeck, B., and Sundelin, J. (1995). Molecular cloning and functional expression of the gene encoding the human proteinase-activatedreceptor 2. Eur. J. Biochem. 232, 84-89.
-
(1995)
Eur. J. Biochem.
, vol.232
, pp. 84-89
-
-
Nystedt, S.1
Emilsson, K.2
Larsson, A.K.3
Strombeck, B.4
Sundelin, J.5
-
33
-
-
85027946204
-
Safety and tolerability of atopaxar in the treat-mentof patientswithacute coronary syndromes: the lessons from antagonizing the cellular effects of Thrombin-Acute Coronary Syndromes Trial
-
O'Donoghue, M. L., Bhatt, D. L., Wiviott, S. D., Goodman, S. G., Fitzgerald, D. J., Angiolillo, D. J., Goto, S., Montalescot, G., Zeymer, U., Aylward, P. E., Guetta, V., Dudek, D., Ziecina, R., Contant, C. F., and Flather, M. D. (2011). Safety and tolerability of atopaxar in the treat-mentof patientswithacute coronary syndromes: the lessons from antagonizing the cellular effects of Thrombin-Acute Coronary Syndromes Trial. Circulation 123, 1843-1853.
-
(2011)
Circulation
, vol.123
, pp. 1843-1853
-
-
O'Donoghue, M.L.1
Bhatt, D.L.2
Wiviott, S.D.3
Goodman, S.G.4
Fitzgerald, D.J.5
Angiolillo, D.J.6
Goto, S.7
Montalescot, G.8
Zeymer, U.9
Aylward, P.E.10
Guetta, V.11
Dudek, D.12
Ziecina, R.13
Contant, C.F.14
Flather, M.D.15
-
34
-
-
1642279517
-
Protease-activated receptors: contribution to physiology and disease
-
Ossovskaya, V. S., and Bunnett, N. W. (2004). Protease-activated receptors: contribution to physiology and disease. Physiol. Rev. 84, 579-621.
-
(2004)
Physiol. Rev.
, vol.84
, pp. 579-621
-
-
Ossovskaya, V.S.1
Bunnett, N.W.2
-
35
-
-
84855376225
-
Targeting proteinase-activated receptors: therapeutic potential and challenges
-
Ramachandran, R., Noorbakhsh, F., Defea, K., and Hollenberg, M. D. (2012). Targeting proteinase-activated receptors: therapeutic potential and challenges. Nat. Rev. Drug Discov. 11, 69-86.
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 69-86
-
-
Ramachandran, R.1
Noorbakhsh, F.2
Defea, K.3
Hollenberg, M.D.4
-
36
-
-
0037335786
-
Mast cell tryptase and proteinase-activated receptor 2 induce hyperexcitability of guinea-pig submucosal neurons
-
Reed, D. E., Barajas-Lopez, C., Cottrell, G., Velazquez-Rocha, S., Dery, O., Grady,E.F.,Bunnett,N.W.,andVan-ner, S. J. (2003). Mast cell tryptase and proteinase-activated receptor 2 induce hyperexcitability of guinea-pig submucosal neurons. J. Physiol. (Lond.) 547, 531-542.
-
(2003)
J. Physiol. (Lond.)
, vol.547
, pp. 531-542
-
-
Reed, D.E.1
Barajas-Lopez, C.2
Cottrell, G.3
Velazquez-Rocha, S.4
Dery, O.5
Grady, E.F.6
Bunnett, N.W.7
Van-ner, S.J.8
-
37
-
-
34247539019
-
A pilot study of fecal serine-protease activity: a pathophysiologic factor in diarrhea-predominant irritable bowel syndrome
-
Roka, R., Rosztoczy, A., Leveque, M., Izbeki, F., Nagy, F., Molnar, T., Lonovics, J., Garcia-Villar, R., Fio-ramonti, J., Wittmann, T., and Bueno, L. (2007). A pilot study of fecal serine-protease activity: a pathophysiologic factor in diarrhea-predominant irritable bowel syndrome. Clin. Gastroenterol. Hepatol. 5, 550-555.
-
(2007)
Clin. Gastroenterol. Hepatol.
, vol.5
, pp. 550-555
-
-
Roka, R.1
Rosztoczy, A.2
Leveque, M.3
Izbeki, F.4
Nagy, F.5
Molnar, T.6
Lonovics, J.7
Garcia-Villar, R.8
Fio-ramonti, J.9
Wittmann, T.10
Bueno, L.11
-
38
-
-
33745012669
-
Impairment of PAR-2-mediated relaxation system in colonic smooth muscle after intestinal inflammation
-
Sato, K., Ninomiya, H., Ohkura, S., Ozaki, H., and Nasu, T. (2006). Impairment of PAR-2-mediated relaxation system in colonic smooth muscle after intestinal inflammation. Br. J. Pharmacol. 148, 200-207.
-
(2006)
Br. J. Pharmacol.
, vol.148
, pp. 200-207
-
-
Sato, K.1
Ninomiya, H.2
Ohkura, S.3
Ozaki, H.4
Nasu, T.5
-
39
-
-
0036083283
-
Cutting-edge technology
-
Schemann, M., Michel, K., Peters, S., Bischoff, S. C., and Neunlist, M. (2002). Cutting-edge technology. III. Imaging and the gastrointestinal tract: mapping the human enteric nervous system. Am. J. Physiol. Gas-trointest. Liver Physiol. 282, G919- G925.
-
(2002)
III. Imaging and the gastrointestinal tract: mapping the human enteric nervous system. Am. J. Physiol. Gas-trointest. Liver Physiol.
, vol.282
-
-
Schemann, M.1
Michel, K.2
Peters, S.3
Bischoff, S.C.4
Neunlist, M.5
-
40
-
-
27744480379
-
Expression of proteinase-activated receptor 2 on human primary gastrointestinal myofibroblasts and stimulationof prostaglandin synthesis
-
Seymour, M. L., Binion, D. G., Comp-ton, S. J., Hollenberg, M. D., and MacNaughton, W. K. (2005). Expression of proteinase-activated receptor 2 on human primary gastrointestinal myofibroblasts and stimulationof prostaglandin synthesis. Can. J. Physiol. Pharmacol. 83, 605-616.
-
(2005)
Can. J. Physiol. Pharmacol.
, vol.83
, pp. 605-616
-
-
Seymour, M.L.1
Binion, D.G.2
Comp-ton, S.J.3
Hollenberg, M.D.4
MacNaughton, W.K.5
-
41
-
-
84860134566
-
Safety of the novel protease-activated receptor-1 antagonist vorapaxar in Japanese patients with a history of ischemic stroke
-
Shinohara, Y., Goto, S., Doi, M., and Jensen, P. (2012). Safety of the novel protease-activated receptor-1 antagonist vorapaxar in Japanese patients with a history of ischemic stroke. J. Stroke Cerebrovasc. Dis. 21, 318-324.
-
(2012)
J. Stroke Cerebrovasc. Dis.
, vol.21
, pp. 318-324
-
-
Shinohara, Y.1
Goto, S.2
Doi, M.3
Jensen, P.4
-
42
-
-
55549136709
-
PAR2 triggers IL-8 release via MEK/ERK and PI3-kinase/Akt pathways in GI epithelial cells
-
Tanaka, Y., Sekiguchi, F., Hong, H., and Kawabata, A. (2008). PAR2 triggers IL-8 release via MEK/ERK and PI3-kinase/Akt pathways in GI epithelial cells. Biochem. Biophys. Res. Com-mun. 377, 622-626.
-
(2008)
Biochem. Biophys. Res. Com-mun.
, vol.377
, pp. 622-626
-
-
Tanaka, Y.1
Sekiguchi, F.2
Hong, H.3
Kawabata, A.4
-
43
-
-
19544392708
-
Clinical relevance of proteinase activated receptors (pars) in the gut
-
Vergnolle, N. (2005). Clinical relevance of proteinase activated receptors (pars) in the gut. Gut 54, 867-874.
-
(2005)
Gut
, vol.54
, pp. 867-874
-
-
Vergnolle, N.1
-
44
-
-
77956764992
-
Recordings from human myen-teric neurons using voltage-sensitive dyes
-
Vignali, S., Peter, N., Ceyhan, G., Demir, I. E., Zeller, F., Senseman, D., Michel, K., and Schemann, M. (2010). Recordings from human myen-teric neurons using voltage-sensitive dyes. J. Neurosci. Methods 192, 240-248.
-
(2010)
J. Neurosci. Methods
, vol.192
, pp. 240-248
-
-
Vignali, S.1
Peter, N.2
Ceyhan, G.3
Demir, I.E.4
Zeller, F.5
Senseman, D.6
Michel, K.7
Schemann, M.8
-
45
-
-
0026035523
-
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
-
Vu, T. K., Hung, D. T., Wheaton, V. I., and Coughlin,S. R. (1991). Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64, 1057-1068.
-
(1991)
Cell
, vol.64
, pp. 1057-1068
-
-
Vu, T.K.1
Hung, D.T.2
Wheaton, V.I.3
Coughlin, S.R.4
-
46
-
-
0032499696
-
Cloning andcharacterizationof human protease-activated receptor 4
-
Xu, W. F., Andersen, H., Whitmore, T. E., Presnell, S. R., Yee, D. P., Ching, A., Gilbert, T., Davie, E. W., and Foster, D. C. (1998). Cloning andcharacterizationof human protease-activated receptor 4. Proc. Natl. Acad. Sci. U.S.A. 95, 6642-6646.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 6642-6646
-
-
Xu, W.F.1
Andersen, H.2
Whitmore, T.E.3
Presnell, S.R.4
Yee, D.P.5
Ching, A.6
Gilbert, T.7
Davie, E.W.8
Foster, D.C.9
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