Rezymogenation of active urokinase induced by an inhibitory antibody

Biochemical Journal

Volumn 449, Issue 1, 2013, Pages 161-166

  Jiang, Longguang ^a   Botkjaer, Kenneth A ^b   Andersen, Lisbeth M ^b   Yuan, Cai ^a   Andreasen, Peter A ^b   Huang, Mingdong ^a  

^a FUJIAN INSTITUTE OF RESEARCH ON THE STRUCTURE OF MATTER   (China)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

Antibody; Autolysis loop; Crystal structure; Protease; Urokinase; Zymogen

Indexed keywords

ANTIBODY; ENZYME PRECURSOR; PROUROKINASE; SERINE PROTEINASE; UROKINASE;

ALLOSTERISM; ANIMAL CELL; ANIMAL TISSUE; ANTIGEN BINDING; ARTICLE; AUTOLYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HUMAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; REGULATORY MECHANISM; REZYMOGENATION; STRUCTURE ANALYSIS;

ANTIBODIES, MONOCLONAL; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; ENZYME INDUCTION; ENZYME PRECURSORS; ENZYME STABILITY; HUMANS; PROTEOLYSIS; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 84870933336     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20121132     Document Type: Article

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