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Volumn 91, Issue 2, 2013, Pages 196-210

SOX2 expression is upregulated in adult spinal cord after contusion injury in both oligodendrocyte lineage and ependymal cells

Author keywords

Gene expression; NG2; Spinal cord injury

Indexed keywords

MESSENGER RNA; TRANSCRIPTION FACTOR SOX2;

EID: 84870929150     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.23151     Document Type: Article
Times cited : (34)

References (68)
  • 1
    • 0034725588 scopus 로고    scopus 로고
    • Modulation of the activity of multiple transcriptional activation domains by the DNA binding domains mediates the synergistic action of Sox2 and Oct-3 on the fibroblast growth factor-4 enhancer
    • Ambrosetti DC, Scholer HR, Dailey L, Basilico C. 2000. Modulation of the activity of multiple transcriptional activation domains by the DNA binding domains mediates the synergistic action of Sox2 and Oct-3 on the fibroblast growth factor-4 enhancer. J Biol Chem 275: 23387-23397.
    • (2000) J Biol Chem , vol.275 , pp. 23387-23397
    • Ambrosetti, D.C.1    Scholer, H.R.2    Dailey, L.3    Basilico, C.4
  • 4
    • 0141756286 scopus 로고    scopus 로고
    • Inflammation, degeneration and regeneration in the injured spinal cord: insights from DNA microarrays
    • Bareyre FM, Schwab ME. 2003. Inflammation, degeneration and regeneration in the injured spinal cord: insights from DNA microarrays. Trends Neurosci 26: 555-563.
    • (2003) Trends Neurosci , vol.26 , pp. 555-563
    • Bareyre, F.M.1    Schwab, M.E.2
  • 5
    • 0037104719 scopus 로고    scopus 로고
    • Long-lasting sprouting and gene expression changes induced by the monoclonal antibody IN-1 in the adult spinal cord
    • Bareyre FM, Haudenschild B, Schwab ME. 2002. Long-lasting sprouting and gene expression changes induced by the monoclonal antibody IN-1 in the adult spinal cord. J Neurosci 22: 7097-7110.
    • (2002) J Neurosci , vol.22 , pp. 7097-7110
    • Bareyre, F.M.1    Haudenschild, B.2    Schwab, M.E.3
  • 9
    • 26944461658 scopus 로고    scopus 로고
    • Sox2 expression defines a heterogeneous population of neurosphere-forming cells in the adult murine brain
    • Brazel CY, Limke TL, Osborne JK, Miura T, Cai J, Pevny L, Rao MS. 2005. Sox2 expression defines a heterogeneous population of neurosphere-forming cells in the adult murine brain. Aging Cell 4: 197-207.
    • (2005) Aging Cell , vol.4 , pp. 197-207
    • Brazel, C.Y.1    Limke, T.L.2    Osborne, J.K.3    Miura, T.4    Cai, J.5    Pevny, L.6    Rao, M.S.7
  • 10
    • 0028306456 scopus 로고
    • Characterization of photochemically induced spinal cord injury in the rat by light and electron microscopy
    • Bunge MB, Holets VR, Bates ML, Clarke TS, Watson BD. 1994. Characterization of photochemically induced spinal cord injury in the rat by light and electron microscopy. Exp Neurol 127: 76-93.
    • (1994) Exp Neurol , vol.127 , pp. 76-93
    • Bunge, M.B.1    Holets, V.R.2    Bates, M.L.3    Clarke, T.S.4    Watson, B.D.5
  • 11
    • 27644545752 scopus 로고    scopus 로고
    • Differential expression of cell fate determinants in neurons and glial cells of adult mouse spinal cord after compression injury
    • Chen J, Leong SY, Schachner M. 2005. Differential expression of cell fate determinants in neurons and glial cells of adult mouse spinal cord after compression injury. Eur J Neurosci 22: 1895-1906.
    • (2005) Eur J Neurosci , vol.22 , pp. 1895-1906
    • Chen, J.1    Leong, S.Y.2    Schachner, M.3
  • 14
    • 25144506952 scopus 로고    scopus 로고
    • Gene expression profiling of experimental traumatic spinal cord injury as a function of distance from impact site and injury severity
    • De Biase A, Knoblach SM, Di Giovanni S, Fan C, Molon A, Hoffman EP, Faden AI. 2005. Gene expression profiling of experimental traumatic spinal cord injury as a function of distance from impact site and injury severity. Physiol Genomics 22: 368-381.
    • (2005) Physiol Genomics , vol.22 , pp. 368-381
    • De Biase, A.1    Knoblach, S.M.2    Di Giovanni, S.3    Fan, C.4    Molon, A.5    Hoffman, E.P.6    Faden, A.I.7
  • 16
    • 13844302847 scopus 로고    scopus 로고
    • SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult
    • Ellis P, Fagan BM, Magness ST, Hutton S, Taranova O, Hayashi S, McMahon A, Rao M, Pevny L. 2004. SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult. Dev Neurosci 26: 148-165.
    • (2004) Dev Neurosci , vol.26 , pp. 148-165
    • Ellis, P.1    Fagan, B.M.2    Magness, S.T.3    Hutton, S.4    Taranova, O.5    Hayashi, S.6    McMahon, A.7    Rao, M.8    Pevny, L.9
  • 18
    • 48749119626 scopus 로고    scopus 로고
    • Regulation of self-renewal and pluripotency by Sox2 in human embryonic stem cells
    • Fong H, Hohenstein KA, Donovan PJ. 2008. Regulation of self-renewal and pluripotency by Sox2 in human embryonic stem cells. Stem Cells 26: 1931-1938.
    • (2008) Stem Cells , vol.26 , pp. 1931-1938
    • Fong, H.1    Hohenstein, K.A.2    Donovan, P.J.3
  • 20
    • 33646577436 scopus 로고    scopus 로고
    • Degenerative and spontaneous regenerative processes after spinal cord injury
    • Hagg T, Oudega M. 2006. Degenerative and spontaneous regenerative processes after spinal cord injury. J Neurotrauma 23: 264-280.
    • (2006) J Neurotrauma , vol.23 , pp. 264-280
    • Hagg, T.1    Oudega, M.2
  • 21
    • 70350619063 scopus 로고    scopus 로고
    • Cellular organization of the central canal ependymal zone, a niche of latent neural stem cells in the adult mammalian spinal cord
    • Hamilton LK, Truong MK, Bednarczyk MR, Aumont A, Fernandes KJ. 2009. Cellular organization of the central canal ependymal zone, a niche of latent neural stem cells in the adult mammalian spinal cord. Neuroscience 164: 1044-1056.
    • (2009) Neuroscience , vol.164 , pp. 1044-1056
    • Hamilton, L.K.1    Truong, M.K.2    Bednarczyk, M.R.3    Aumont, A.4    Fernandes, K.J.5
  • 22
    • 33747157935 scopus 로고    scopus 로고
    • Fate of endogenous stem/progenitor cells following spinal cord injury
    • Horky LL, Galimi F, Gage FH, Horner PJ. 2006. Fate of endogenous stem/progenitor cells following spinal cord injury. J Comp Neurol 498: 525-538.
    • (2006) J Comp Neurol , vol.498 , pp. 525-538
    • Horky, L.L.1    Galimi, F.2    Gage, F.H.3    Horner, P.J.4
  • 24
    • 0033534379 scopus 로고    scopus 로고
    • Identification of a neural stem cell in the adult mammalian central nervous system
    • Johansson CB, Momma S, Clarke DL, Risling M, Lendahl U, Frisen J. 1999. Identification of a neural stem cell in the adult mammalian central nervous system. Cell 96: 25-34.
    • (1999) Cell , vol.96 , pp. 25-34
    • Johansson, C.B.1    Momma, S.2    Clarke, D.L.3    Risling, M.4    Lendahl, U.5    Frisen, J.6
  • 25
    • 43749093843 scopus 로고    scopus 로고
    • Interleukin-6 induces proliferation in adult spinal cord-derived neural progenitors via the JAK2/STAT3 pathway with EGF-induced MAPK phosphorylation
    • Kang MK, Kang SK. 2008. Interleukin-6 induces proliferation in adult spinal cord-derived neural progenitors via the JAK2/STAT3 pathway with EGF-induced MAPK phosphorylation. Cell Prolif 41: 377-392.
    • (2008) Cell Prolif , vol.41 , pp. 377-392
    • Kang, M.K.1    Kang, S.K.2
  • 26
    • 33645455547 scopus 로고    scopus 로고
    • Delayed transplantation of adult neural precursor cells promotes remyelination and functional neurological recovery after spinal cord injury
    • Karimi-Abdolrezaee S, Eftekharpour E, Wang J, Morshead CM, Fehlings MG. 2006. Delayed transplantation of adult neural precursor cells promotes remyelination and functional neurological recovery after spinal cord injury. J Neurosci 26: 3377-3389.
    • (2006) J Neurosci , vol.26 , pp. 3377-3389
    • Karimi-Abdolrezaee, S.1    Eftekharpour, E.2    Wang, J.3    Morshead, C.M.4    Fehlings, M.G.5
  • 27
    • 33745500882 scopus 로고    scopus 로고
    • Early response of endogenous adult neural progenitor cells to acute spinal cord injury in mice
    • Ke Y, Chi L, Xu R, Luo C, Gozal D, Liu R. 2006. Early response of endogenous adult neural progenitor cells to acute spinal cord injury in mice. Stem Cells 24: 1011-1019.
    • (2006) Stem Cells , vol.24 , pp. 1011-1019
    • Ke, Y.1    Chi, L.2    Xu, R.3    Luo, C.4    Gozal, D.5    Liu, R.6
  • 29
    • 5644269242 scopus 로고    scopus 로고
    • Sox-2 is expressed by neural progenitors and astroglia in the adult rat brain
    • Komitova M, Eriksson PS. 2004. Sox-2 is expressed by neural progenitors and astroglia in the adult rat brain. Neurosci Lett 369: 24-27.
    • (2004) Neurosci Lett , vol.369 , pp. 24-27
    • Komitova, M.1    Eriksson, P.S.2
  • 30
    • 34047245282 scopus 로고    scopus 로고
    • Glial cell loss, proliferation and replacement in the contused murine spinal cord
    • Lytle JM, Wrathall JR. 2007. Glial cell loss, proliferation and replacement in the contused murine spinal cord. Eur J Neurosci 25: 1711-1724.
    • (2007) Eur J Neurosci , vol.25 , pp. 1711-1724
    • Lytle, J.M.1    Wrathall, J.R.2
  • 31
    • 65149090344 scopus 로고    scopus 로고
    • NG2 cell response in the CNP-EGFP mouse after contusive spinal cord injury
    • Lytle JM, Chittajallu R, Wrathall JR, Gallo V. 2009. NG2 cell response in the CNP-EGFP mouse after contusive spinal cord injury. Glia 57: 270-285.
    • (2009) Glia , vol.57 , pp. 270-285
    • Lytle, J.M.1    Chittajallu, R.2    Wrathall, J.R.3    Gallo, V.4
  • 32
    • 0018568754 scopus 로고
    • An electron microscopic analysis of abnormal ependymal cell proliferation and envelopment of sprouting axons following spinal cord transection in the rat
    • Matthews MA, St. Onge MF, Faciane CL. 1979. An electron microscopic analysis of abnormal ependymal cell proliferation and envelopment of sprouting axons following spinal cord transection in the rat. Acta Neuropathol 45: 27-36.
    • (1979) Acta Neuropathol , vol.45 , pp. 27-36
    • Matthews, M.A.1    St. Onge, M.F.2    Faciane, C.L.3
  • 33
    • 0035873062 scopus 로고    scopus 로고
    • Proliferation of NG2-positive cells and altered oligodendrocyte numbers in the contused rat spinal cord
    • McTigue DM, Wei P, Stokes BT. 2001. Proliferation of NG2-positive cells and altered oligodendrocyte numbers in the contused rat spinal cord. J Neurosci 21: 3392-3400.
    • (2001) J Neurosci , vol.21 , pp. 3392-3400
    • McTigue, D.M.1    Wei, P.2    Stokes, B.T.3
  • 35
    • 0030249817 scopus 로고    scopus 로고
    • Increased basic fibroblast growth factor expression following contusive spinal cord injury
    • Mocchetti I, Rabin SJ, Colangelo AM, Whittemore SR, Wrathall JR. 1996. Increased basic fibroblast growth factor expression following contusive spinal cord injury. Exp Neurol 141: 154-164.
    • (1996) Exp Neurol , vol.141 , pp. 154-164
    • Mocchetti, I.1    Rabin, S.J.2    Colangelo, A.M.3    Whittemore, S.R.4    Wrathall, J.R.5
  • 37
    • 12844282237 scopus 로고    scopus 로고
    • Proliferation, migration, and differentiation of endogenous ependymal region stem/progenitor cells following minimal spinal cord injury in the adult rat
    • Mothe AJ, Tator CH. 2005. Proliferation, migration, and differentiation of endogenous ependymal region stem/progenitor cells following minimal spinal cord injury in the adult rat. Neuroscience 131: 177-187.
    • (2005) Neuroscience , vol.131 , pp. 177-187
    • Mothe, A.J.1    Tator, C.H.2
  • 38
    • 0032895971 scopus 로고    scopus 로고
    • Cell proliferation and nestin expression in the ependyma of the adult rat spinal cord after injury
    • Namiki J, Tator CH. 1999. Cell proliferation and nestin expression in the ependyma of the adult rat spinal cord after injury. J Neuropathol Exp Neurol 58: 489-498.
    • (1999) J Neuropathol Exp Neurol , vol.58 , pp. 489-498
    • Namiki, J.1    Tator, C.H.2
  • 39
    • 0038015593 scopus 로고    scopus 로고
    • The stem-cell menagerie
    • Pevny L, Rao MS. 2003. The stem-cell menagerie. Trends Neurosci 26: 351-359.
    • (2003) Trends Neurosci , vol.26 , pp. 351-359
    • Pevny, L.1    Rao, M.S.2
  • 40
    • 23844506901 scopus 로고    scopus 로고
    • Cellular transplantation strategies for spinal cord injury and translational neurobiology
    • Reier PJ. 2004. Cellular transplantation strategies for spinal cord injury and translational neurobiology. NeuroRx 1: 424-451.
    • (2004) NeuroRx , vol.1 , pp. 424-451
    • Reier, P.J.1
  • 41
    • 75349094565 scopus 로고    scopus 로고
    • Challenges of stem cell therapy for spinal cord injury: human embryonic stem cells, endogenous neural stem cells, or induced pluripotent stem cells?
    • Ronaghi M, Erceg S, Moreno-Manzano V, Stojkovic M. 2010. Challenges of stem cell therapy for spinal cord injury: human embryonic stem cells, endogenous neural stem cells, or induced pluripotent stem cells? Stem Cells 28: 93-99.
    • (2010) Stem Cells , vol.28 , pp. 93-99
    • Ronaghi, M.1    Erceg, S.2    Moreno-Manzano, V.3    Stojkovic, M.4
  • 42
    • 77954862426 scopus 로고    scopus 로고
    • Stem cell therapies for spinal cord injury
    • Sahni V, Kessler JA. 2010. Stem cell therapies for spinal cord injury. Nat Rev Neurol 6: 363-372.
    • (2010) Nat Rev Neurol , vol.6 , pp. 363-372
    • Sahni, V.1    Kessler, J.A.2
  • 43
    • 73649108566 scopus 로고    scopus 로고
    • Are induced pluripotent stem cells the future of cell-based regenerative therapies for spinal cord injury?
    • Salewski RP, Eftekharpour E, Fehlings MG. 2010. Are induced pluripotent stem cells the future of cell-based regenerative therapies for spinal cord injury? J Cell Physiol 222: 515-521.
    • (2010) J Cell Physiol , vol.222 , pp. 515-521
    • Salewski, R.P.1    Eftekharpour, E.2    Fehlings, M.G.3
  • 44
    • 0037311388 scopus 로고    scopus 로고
    • Apolipoprotein E expression after spinal cord injury in the mouse
    • Seitz A, Kragol M, Aglow E, Showe L, Heber-Katz E. 2003. Apolipoprotein E expression after spinal cord injury in the mouse. J Neurosci Res 71: 417-426.
    • (2003) J Neurosci Res , vol.71 , pp. 417-426
    • Seitz, A.1    Kragol, M.2    Aglow, E.3    Showe, L.4    Heber-Katz, E.5
  • 45
    • 36148930166 scopus 로고    scopus 로고
    • Therapeutic applications of oligodendrocyte precursors derived from human embryonic stem cells
    • Sharp J, Keirstead HS. 2007. Therapeutic applications of oligodendrocyte precursors derived from human embryonic stem cells. Curr Opin Biotechnol 18: 434-440.
    • (2007) Curr Opin Biotechnol , vol.18 , pp. 434-440
    • Sharp, J.1    Keirstead, H.S.2
  • 46
    • 84861857672 scopus 로고    scopus 로고
    • Self-renewal and differentiation of reactive astrocyte-derived neural stem/progenitor cells isolated from the cortical peri-infarct area after stroke
    • Shimada IS, LeComte MD, Granger JC, Quinlan NJ, Spees JL. 2012. Self-renewal and differentiation of reactive astrocyte-derived neural stem/progenitor cells isolated from the cortical peri-infarct area after stroke. J Neurosci 32: 7926-7940.
    • (2012) J Neurosci , vol.32 , pp. 7926-7940
    • Shimada, I.S.1    LeComte, M.D.2    Granger, J.C.3    Quinlan, N.J.4    Spees, J.L.5
  • 47
    • 0037135287 scopus 로고    scopus 로고
    • Analysis of gene expression following spinal cord injury in rat using complementary DNA microarray
    • Tachibana T, Noguchi K, Ruda MA. 2002. Analysis of gene expression following spinal cord injury in rat using complementary DNA microarray. Neurosci Lett 327: 133-137.
    • (2002) Neurosci Lett , vol.327 , pp. 133-137
    • Tachibana, T.1    Noguchi, K.2    Ruda, M.A.3
  • 48
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. 2006. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126: 663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 50
    • 52649083768 scopus 로고    scopus 로고
    • Involvement of acidic fibroblast growth factor in spinal cord injury repair processes revealed by a proteomics approach
    • Tsai MC, Shen LF, Kuo HS, Cheng H, Chak KF. 2008. Involvement of acidic fibroblast growth factor in spinal cord injury repair processes revealed by a proteomics approach. Mol Cell Proteomics 7: 1668-1687.
    • (2008) Mol Cell Proteomics , vol.7 , pp. 1668-1687
    • Tsai, M.C.1    Shen, L.F.2    Kuo, H.S.3    Cheng, H.4    Chak, K.F.5
  • 51
    • 0028909220 scopus 로고
    • Embryonic expression of the chicken Sox2, Sox3 and Sox11 genes suggests an interactive role in neuronal development
    • Uwanogho D, Rex M, Cartwright EJ, Pearl G, Healy C, Scotting PJ, Sharpe PT. 1995. Embryonic expression of the chicken Sox2, Sox3 and Sox11 genes suggests an interactive role in neuronal development. Mech Dev 49: 23-36.
    • (1995) Mech Dev , vol.49 , pp. 23-36
    • Uwanogho, D.1    Rex, M.2    Cartwright, E.J.3    Pearl, G.4    Healy, C.5    Scotting, P.J.6    Sharpe, P.T.7
  • 53
    • 0029860591 scopus 로고    scopus 로고
    • Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis
    • Weiss S, Dunne C, Hewson J, Wohl C, Wheatley M, Peterson AC, Reynolds BA. 1996. Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis. J Neurosci 16: 7599-7609.
    • (1996) J Neurosci , vol.16 , pp. 7599-7609
    • Weiss, S.1    Dunne, C.2    Hewson, J.3    Wohl, C.4    Wheatley, M.5    Peterson, A.C.6    Reynolds, B.A.7
  • 56
    • 47849122782 scopus 로고    scopus 로고
    • Stem cells in spinal cord injury
    • Wrathall JR, Lytle JM. 2008. Stem cells in spinal cord injury. Dis Markers 24: 239-250.
    • (2008) Dis Markers , vol.24 , pp. 239-250
    • Wrathall, J.R.1    Lytle, J.M.2
  • 57
    • 0021917038 scopus 로고
    • Spinal cord contusion in the rat: production of graded, reproducible, injury groups
    • Wrathall JR, Pettegrew RK, Harvey F. 1985. Spinal cord contusion in the rat: production of graded, reproducible, injury groups. Exp Neurol 88: 108-122.
    • (1985) Exp Neurol , vol.88 , pp. 108-122
    • Wrathall, J.R.1    Pettegrew, R.K.2    Harvey, F.3
  • 59
    • 79952528796 scopus 로고    scopus 로고
    • Increased expression of the close homolog of the adhesion molecule L1 in different cell types over time after rat spinal cord contusion
    • Wu J, Leung PY, Sharp A, Lee HJ, Wrathall JR. 2011. Increased expression of the close homolog of the adhesion molecule L1 in different cell types over time after rat spinal cord contusion. J Neurosci Res 89: 628-638.
    • (2011) J Neurosci Res , vol.89 , pp. 628-638
    • Wu, J.1    Leung, P.Y.2    Sharp, A.3    Lee, H.J.4    Wrathall, J.R.5
  • 60
    • 18844367661 scopus 로고    scopus 로고
    • Real-time quantitative PCR analysis of temporal-spatial alterations in gene expression after spinal cord contusion
    • Wu X, Yoo S, Wrathall JR. 2005. Real-time quantitative PCR analysis of temporal-spatial alterations in gene expression after spinal cord contusion. J Neurochem 93: 943-952.
    • (2005) J Neurochem , vol.93 , pp. 943-952
    • Wu, X.1    Yoo, S.2    Wrathall, J.R.3
  • 62
    • 0035214298 scopus 로고    scopus 로고
    • Proliferation of parenchymal neural progenitors in response to injury in the adult rat spinal cord
    • Yamamoto S, Yamamoto N, Kitamura T, Nakamura K, Nakafuku M. 2001b. Proliferation of parenchymal neural progenitors in response to injury in the adult rat spinal cord. Exp Neurol 172: 115-127.
    • (2001) Exp Neurol , vol.172 , pp. 115-127
    • Yamamoto, S.1    Yamamoto, N.2    Kitamura, T.3    Nakamura, K.4    Nakafuku, M.5
  • 65
    • 34447574996 scopus 로고    scopus 로고
    • Mixed primary culture and clonal analysis provide evidence that NG2 proteoglycan-expressing cells after spinal cord injury are glial progenitors
    • Yoo S, Wrathall JR. 2007. Mixed primary culture and clonal analysis provide evidence that NG2 proteoglycan-expressing cells after spinal cord injury are glial progenitors. Dev Neurobiol 67: 860-874.
    • (2007) Dev Neurobiol , vol.67 , pp. 860-874
    • Yoo, S.1    Wrathall, J.R.2
  • 66
    • 20044362061 scopus 로고    scopus 로고
    • Cell proliferation and replacement following contusive spinal cord injury
    • Zai LJ, Wrathall JR. 2005. Cell proliferation and replacement following contusive spinal cord injury. Glia 50: 247-257.
    • (2005) Glia , vol.50 , pp. 247-257
    • Zai, L.J.1    Wrathall, J.R.2
  • 67
    • 23644450196 scopus 로고    scopus 로고
    • Increased growth factor expression and cell proliferation after contusive spinal cord injury
    • Zai LJ, Yoo S, Wrathall JR. 2005. Increased growth factor expression and cell proliferation after contusive spinal cord injury. Brain Res 1052: 147-155.
    • (2005) Brain Res , vol.1052 , pp. 147-155
    • Zai, L.J.1    Yoo, S.2    Wrathall, J.R.3
  • 68
    • 0034044574 scopus 로고    scopus 로고
    • Sox2 regulatory sequences direct expression of a β-geo transgene to telencephalic neural stem cells and precursors of the mouse embryo, revealing regionalization of gene expression in CNS stem cells
    • Zappone MV, Galli R, Catena R, Meani N, De Biasi S, Mattei E, Tiveron C, Vescovi AL, Lovell-Badge R, Ottolenghi S, Nicolis SK. 2000. Sox2 regulatory sequences direct expression of a β-geo transgene to telencephalic neural stem cells and precursors of the mouse embryo, revealing regionalization of gene expression in CNS stem cells. Development 127: 2367-2382.
    • (2000) Development , vol.127 , pp. 2367-2382
    • Zappone, M.V.1    Galli, R.2    Catena, R.3    Meani, N.4    De Biasi, S.5    Mattei, E.6    Tiveron, C.7    Vescovi, A.L.8    Lovell-Badge, R.9    Ottolenghi, S.10    Nicolis, S.K.11


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