Enantioselective synthesis of axially chiral tetrasubstituted allenes via lipase-catalyzed desymmetrization

Synthesis (Germany)

Volumn 44, Issue 24, 2012, Pages 3789-3796

  Hammel, Matthias ^a   Deska, Jan ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

5 endo trig cyclization; allenes; axial chirality; biocatalysis; desymmetrization

Indexed keywords

ALLENES; ALLENYL; AXIAL CHIRALITY; BIOCATALYSIS; CYCLIZATIONS; DESYM-METRIZATION; DIHYDROFURANS; ENANTIOSELECTIVE SYNTHESIS; LIPASE-CATALYZED; MONOESTERS; OPTICAL PURITY; PSEUDOMONAS FLUORESCENS;

CATALYSIS; CYCLIZATION;

HYDROCARBONS;

2 ACETOXY 5,5 DIMETHYL 2 (PROP 1 YNYL) 1,3 DIOXANE; 2 ACETOXY 5,5 DIMETHYL 2 PHENYLETHYNYL 1,3 DIOXANE; 2 HYDROXYMETHYL 4 (2 NAPHTHYL)PENTA 2,3 DIEN 1 YL BUTYRIC ACID; 2 HYDROXYMETHYL 4 (4 METHOXYPHENYL)PENTA 2,3 DIEN 1 OL; 2 HYDROXYMETHYL 4 (4 METHOXYPHENYL)PENTA 2,3 DIEN 1 YL BUTYRIC ACID; 2 HYDROXYMETHYL 4 METHYLUNDECA 2,3 DIEN 5 YN 1 OL; 2 HYDROXYMETHYL 4 METHYLUNDECA 2,3 DIEN 5 YN 1 YL BUTYRIC ACID; 2 HYDROXYMETHYL 4 PHENYLHEPTA 2,3 DIEN 1 OL; 2 HYDROXYMETHYL 4 PHENYLHEPTA 2,3 DIEN 1 YL BUTYRIC ACID; 2 HYDROXYMETHYL 4 PHENYLHEXA 2,3 DIEN 1 OL; 2 HYDROXYMETHYL 4 PHENYLHEXA 2,3 DIEN 1 YL BUTYRIC ACID; 2 HYDROXYMETHYL 4 PHENYLOCTA 2, DIEN 1 OL; 2 HYDROXYMETHYL 4 PHENYLOCTA 2,3 DIEN 1 YL BUTYRIC ACID; 2 HYDROXYMETHYL 4 PHENYLPENTA 2,3 DIEN 1 OL; 2 HYDROXYMETHYL 4 PHENYLPENTA 2,3 DIEN 1 YL BUTYRIC ACID; 3 IODO 2 METHYL 2 PHENYL 2,5 DIHYDROFURAN 4 YLMETHYL BUTYRIC ACID; 4 (4 CHLOROPHENYL) 2 HYDROXYMETHYLPENTA 2,3 DIEN 1 OL; 4 (4 CHLOROPHENYL) 2 HYDROXYMETHYLPENTA 2,3 DIEN 1 YL BUTYRIC ACID; 4 HYDROXYMETHYL 2 ,ETHYL 2 PHENYL 2,5 DIHYDROFURAN; ALLENE DERIVATIVE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ARTICLE; ASYMMETRIC SYNTHESIS; BIOCATALYSIS; CANDIDA ANTARCTICA; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; CHIRALITY; CYCLIZATION; ENANTIOSELECTIVITY; INFRARED SPECTROSCOPY; ISOMERIZATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS FLUORESCENS; REACTION TIME; STEREOCHEMISTRY; SYNTHESIS; TRANSESTERIFICATION;

EID: 84870929133     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0032-1317524     Document Type: Article

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