Covalently linked tandem lesions in DNA

Radiation Research

Volumn 178, Issue 6, 2012, Pages 538-542

  Patrzyc, Helen B ^a   Dawidzik, Jean B ^a   Budzinski, Edwin E ^a   Freund, Harold G ^a   Wilton, John H ^a   Box, Harold C ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA;

AQUEOUS SOLUTION; ARTICLE; COVALENT BOND; COVALENTLY LINKED DNA TANDEM LESION; DEOXYGENATION; DNA DAMAGE; DNA STRUCTURE; LIQUID CHROMATOGRAPHY; NONHUMAN; OXYGENATION; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY; X IRRADIATION;

ANIMALS; CATTLE; DNA; DNA DAMAGE; OXYGEN; X-RAYS;

EID: 84870914647     PISSN: 00337587     EISSN: 19385404     Source Type: Journal    
DOI: 10.1667/RR2915.1     Document Type: Article

References (18)

1. Box HC, BudzinskI EE, Dawidzik JD, Wallace JC, Evans MS, Gobey JS. Radiation-induced formation of a crosslink between base moieties of deoxyguanosine and thymidine in deoxygenated solutions of d(CpGpTpA). Radiat Res 1996; 145:641-3.
2. Box HC, Patrzyc HB, Dawidzik JB, Wallace JC, Freund HG, Iijima H, et al. Double base lesions in DNA X-irradiated in the presence and absence of oxygen. Radiat Res 2000; 153:442-6.
3. Box HC, Dawidzik JB, Budzinski EE. Free radical-induced double lesions in DNA. Free Radic Biol Med 2001; 31:856-68.
4. Box HC, Budzinski EE, Dawidzik JB, Wallace JC, Iijima H. Tandem lesions and other products in X-irradiated DNA oligomers. Radiat Res 1998; 149: 433-9.
5. Hong H, Cao H, Wang Y. Formation and genotoxicity of a guanine-cytosine intrastrand cross-link lesion in vivo. Nucleic Acids Res 2007; 35:7118-27.
6. Colis LC, Raychaudhury P, Basu AK. Mutational specificity of γ-radiation-induced guanine-thymine and thymine-guanine intrastrand cross-links in mammalian cells and translesion synthesis past the guanine-thymine lesion by human DNA polymerase η. Biochemistry 2008; 47:8070-9.
7. Iijima H, Patrzyc HB, Budzinski EE, Freund HG, Dawidzik JB, Rodabaugh HJ, et al. A study of pyrimidine base damage in relation to oxidaive stress and cancer. Br J Cancer 2009; 101:452-6.
8. Box HC, Budzinski EE, Freund HG, Evans MS, Patrzyc HB, Wallace JC, et al. Vicinal lesions in X-irradiated DNA? Int J Radiat Biol 1993; 64: 261-3.
9. Box HC, Freund HG, Budzinski EE, Wallace JC, Maccubbin AE. Free radical-induced double base lesions. Radiat Res 1995; 141:91-4.
10. Yang Z, Colis LC, Basu AK, Zou Y. Recognition and incision of γ-radiation-induced cross-linked guanine-thymine tandem lesion G[8,5-Me]T by UvrABC nuclease. Chem Res Toxicol 2005; 18:1339-46.
11. Bellon S, Gasparutto D, Saint-Pierre C, Cadet J. Guanine-thymine intrastrand cross-linked lesion containing oligonucleotides: from chemical synthesis to in vitro enzymatic replication. Org Biomol Chem 2006; 4:3831-7.
12. Bellon S, Ravanat JL, Gasparutto D, Cadet J. Cross-linked thymine-purine base tandem lesions: synthesis, characterization, and measurement in γ-irradiated isolated DNA. Chem Res Toxicol 2002; 15:598-606.
13. Huang H, Imoto S, Greenberg MM. The mutagenicity of thymine glycol in Escherichia coli is increased when it is part of a tandem lesion. Biochemistry 2009; 48:7833-41.
14. Jiang Y, Hong H, Cao H, Wang Y. In vivo formation and in vitro replication of a guanine-thymine intrasrand cross-link lesion. Biochemistry 2007; 46:12757-63.
15. Gentil A, Le Page F, Cadet J, Sarasin A. Mutational spectra induced by replication to two vicinal oxidative DNA lesions in mammalian cells. Mutat Res 2010; 452:51-6.
16. Yuan B, Jiang Y, Wang Y, Wang Y. Efficient formation of the tandem thymine glycol/8-oxo-7,8-dihydroguanine lesion in isolated DNA and the mutagenic and cytotoxic properties of the tandem lesions in Escherichia coli cells. Chem Res Toxicol 2009; 23:11-9.
17. BrCA) and duplex DNA containing a 5-bromocytosine. J Am Chem Soc 2005; 127:13969-77.
18. Wang J, Cao H, You C, Yuan B, Bahde R, Gupta S, et al. Endogenous formation and repair of oxidatively induced G[8-5m]T intrastrand cross-link lesion. Nucl Acids Res 2012. (doi:10. 1093/nar/gks357)