Kinetic characterization of the critical step in HIV-1 protease maturation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 50, 2012, Pages 20449-20454

  Sadiq, S Kashif ^a   Noé, Frank ^b   De Fabritiis, Gianni ^a  

^a UNIVERSITAT POMPEU FABRA   (Spain)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Conformational kinetics; High throughput molecular dynamics; Markov state model

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE; MONOMER;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROCESSING; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; ENZYME PRECURSORS; HIV PROTEASE; HIV-1; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; PROTEIN PROCESSING, POST-TRANSLATIONAL;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84870912649     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1210983109     Document Type: Article

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