APP independent and dependent effects on neurite outgrowth are modulated by the receptor associated protein (RAP)

Journal of Neurochemistry

Volumn 124, Issue 1, 2013, Pages 123-132

  Billnitzer, Andrew J ^a   Barskaya, Irina ^b   Yin, Cailing ^c   Perez, Ruth G ^a,c  

^a MSB 1   (United States)

^b ALLEGHENY GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

axon branching; axon growth; dendritic branching; dendritic growth; low density lipoprotein receptor related protein

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CHAPERONE; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; RECEPTOR ASSOCIATED PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENDRITE; EMBRYO; IN VITRO STUDY; MOUSE; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ASTROCYTES; BUTADIENES; CARRIER PROTEINS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO, MAMMALIAN; ENZYME INHIBITORS; HIPPOCAMPUS; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-1; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURITES; NEURONS; NITRILES; TUBULIN;

EID: 84870906520     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12051     Document Type: Article

References (51)

1. von Bohlen und Halbach O., (2011) Immunohistological markers for proliferative events, gliogenesis, and neurogenesis within the adult hippocampus. Cell Tissue Res. 345, 1-19.
2. Bu G., and, Rennke S., (1996) Receptor-associated protein is a folding chaperone for low density lipoprotein receptor-related protein. J. Biol. Chem. 271, 22218-22224. (Pubitemid 26303856)
3. Chasseigneaux S., Dinc L., Rose C., Chabret C., Coulpier F., Topilko P., Mauger G., and, Allinquant B., (2011) Secreted amyloid precursor protein beta and secreted amyloid precursor protein alpha induce axon outgrowth in vitro through Egr1 signaling pathway. PLoS ONE 6, e16301.
4. Conboy L., Murphy K. J., and, Regan C. M., (2005) Amyloid precursor protein expression in the rat hippocampal dentate gyrus modulates during memory consolidation. J. Neurochem. 95, 1677-1688. (Pubitemid 41804064)
5. Cotman C. W., Geddes J. W., and, Kahle J. S., (1990) Axon sprouting in the rodent and Alzheimer's disease brain: a reactivation of developmental mechanisms? Prog. Brain Res. 83, 427-434. (Pubitemid 20205296)
6. Dawson G. R., Seabrook G. R., Zheng H., et al,. (1999) Age-related cognitive deficits, impaired long-term potentiation and reduction in synaptic marker density in mice lacking the beta-amyloid precursor protein. Neuroscience 90, 1-13. (Pubitemid 29096448)
7. De Strooper B., and, Annaert W., (2000) Proteolytic processing and cell biological functions of the amyloid precursor protein. J. Cell Sci. 113 (Pt 11), 1857-1870. (Pubitemid 30386490)
8. DeKosky S. T., and, Scheff S. W., (1990) Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity. Ann. Neurol. 27, 457-464. (Pubitemid 20149963)
9. Eriksson P. S., Perfilieva E., Bjork-Eriksson T., Alborn A. M., Nordborg C., Peterson D. A., and, Gage F. H., (1998) Neurogenesis in the adult human hippocampus. Nat. Med. 4, 1313-1317. (Pubitemid 28512114)
10. Glenner G. G., and, Wong C. W., (1984) Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem. Biophys. Res. Commun. 120, 885-890. (Pubitemid 14104991)
11. Goslin K., and, Banker G., (1991) Culturing nerve cells, in Cellular and Molecular Neuroscience Series (, Banker G., and, Goslin K., eds), pp. 251-281. MIT Press, Cambridge.
12. Gralle M., and, Ferreira S. T., (2007) Structure and functions of the human amyloid precursor protein: the whole is more than the sum of its parts. Prog. Neurobiol. 82, 11-32. (Pubitemid 46719589)
13. Herz J., (2001) The LDL receptor gene family: (un)expected signal transducers in the brain. Neuron 29, 571-581. (Pubitemid 32323932)
14. Ho V. M., Lee J. A., and, Martin K. C., (2011) The cell biology of synaptic plasticity. Science 334, 623-628.
15. Hui Z., and, Koo E. H., (2006) The amyloid precursor protein: beyond amyloid. Mol. Neurodegener. 1, 5-12.
16. Hui Z., and, Koo E. H., (2011) Biology and pathophysiology of the amyloid precursor protein. Mol. Neurodegener. 6, 27-42.
17. Ikin A. F., Sabo S. L., Lanier L. M., and, Buxbaum J. D., (2007) A macromolecular complex involving the amyloid precursor protein (APP) and the cytosolic adapter FE65 is a negative regulator of axon branching. Mol. Cell. Neurosci. 35, 57-63. (Pubitemid 46636301)
18. Johnson S. A., McNeill T., Cordell B., and, Finch C. E., (1990) Relation of neuronal APP-751/APP-695 mRNA ratio and neuritic plaque density in Alzheimer's disease. Science 248, 854-857.
19. Jordan J., Galindo M. F., Miller R. J., Reardon C. A., Getz G. S., and, LaDu M. J., (1998) Isoform-specific effect of apolipoprotein E on cell survival and beta-amyloid-induced toxicity in rat hippocampal pyramidal neuronal cultures. J. Neurosci. 18, 195-204. (Pubitemid 28046781)
20. Kametani F., Tanaka K., Ishii T., Ikeda S., Kennedy H. E., and, Allsop D., (1993) Secretory form of Alzheimer amyloid precursor protein 695 in human brain lacks beta/A4 amyloid immunoreactivity. Biochem. Biophys. Res. Commun. 191, 392-398. (Pubitemid 23222648)
21. Kang D. E., Saitoh T., Chen X., Xia Y., Masliah E., Hansen L. A., Thomas R. G., Thal L. J., and, Katzman R., (1997) Genetic association of the low-density lipoprotein receptor-related protein gene (LRP), an apolipoprotein E receptor, with late-onset Alzheimer's disease. Neurology 49, 56-61. (Pubitemid 27328682)
22. Kimmel C. B., (1993) Patterning the brain of the zebrafish embryo. Annu. Rev. Neurosci. 16, 707-732. (Pubitemid 23074024)
23. Kounnas M. Z., Moir R. D., Rebeck G. W., Bush A. I., Argraves W. S., Tanzi R. E., Hyman B. T., and, Strickland D. K., (1995) LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted beta-amyloid precursor protein and mediates its degradation. Cell 82, 331-340.
24. Li H. L., Roch J. M., Sundsmo M., Otero D., Sisodia S., Thomas R., and, Saitoh T., (1997) Defective neurite extension is caused by a mutation in amyloid beta/A4 (A beta) protein precursor found in familial Alzheimer's disease. J. Neurobiol. 32, 469-480. (Pubitemid 27172933)
25. Lillis A. P., Van Duyn L. B., Murphy-Ullrich J. E., and, Strickland D. K., (2008) LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies. Physiol. Rev. 88, 887-918.
26. Lin E., Cavanaugh J. E., Leak R. K., Perez R. G., and, Zigmond M. J., (2008) Rapid activation of ERK by 6-hydroxydopamine promotes survival of dopaminergic cells. J. Neurosci. Res. 86, 108-117.
27. Löffler J., and, Huber G., (1992) Beta-amyloid precursor protein isoforms in various rat brain regions and during brain development. J. Neurochem. 59, 1316-1324.
28. Masliah E., Mallory M., Hansen L., Alford M., Albright T., DeTeresa R., Terry R., Baudier J., and, Saitoh T., (1991) Patterns of aberrant sprouting in Alzheimer's disease. Neuron 6, 729-739.
29. Mattson M. P., (1997) Cellular actions of...-Amyloid precursor protein and its soluble and fibrillogenic derivatives. Physiol. Rev. 77, 1081.
30. Perez R. G., Zheng H., Van der Ploeg L. H., and, Koo E. H., (1997) The beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity. J. Neurosci. 17, 9407-9414. (Pubitemid 28006385)
31. Perez R. G., Soriano S., Hayes J. D., Ostaszewski B., Xia W., Selkoe D. J., Chen X., Stokin G. B., and, Koo E. H., (1999) Mutagenesis identifies new signals for beta-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Abeta42. J. Biol. Chem. 274, 18851-18856.
32. Perron J. C., and, Bixby J. L., (1999) Distinct neurite outgrowth signaling pathways converge on ERK activation. Mol. Cell. Neurosci. 13, 362-378. (Pubitemid 29256876)
33. Qiu Z., Hyman B. T., and, Rebeck G. W., (2004) Apolipoprotein E receptors mediate neurite outgrowth through activation of p44/42 mitogen-activated protein kinase in primary neurons. J. Biol. Chem. 279, 34948-34956. (Pubitemid 39318131)
34. Reyes-Reyes M., Mora N., Gonzalez G., and, Rosales C., (2002) Beta1 and beta2 integrins activate different signalling pathways in monocytes. Biochem. J. 363, 273-280. (Pubitemid 34415763)
35. Ring S., Weyer S. W., Kilian S. B., et al,. (2007) The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice. J. Neurosci. 27, 7817-7826. (Pubitemid 47093823)
36. Seabrook G. R., Smith D. W., Bowery B. J., et al,. (1999) Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein. Neuropharmacology 38, 349-359. (Pubitemid 29097718)
37. Selkoe D. J., (2012) Preventing Alzheimer's disease. Science 337, 1488-1492.
38. Selkoe D. J., Yamazaki T., Citron M., Podlisny M. B., Koo E. H., Teplow D. B., and, Haass C., (1996) The role of APP processing and trafficking pathways in the formation of amyloid beta-protein. Ann. N. Y. Acad. Sci. 777, 57-64. (Pubitemid 26149170)
39. Suzuki W. A., (2007) Making new memories. Ann. N. Y. Acad. Sci. 1097, 1-11.
40. Thinakaran G., and, Koo E. H., (2008) Amyloid precursor protein trafficking, processing, and function. J. Biol. Chem. 283, 29615-29619.
41. Ugarte S. D., Lin E., Klann E., Zigmond M. J., and, Perez R. G., (2003) Effects of GDNF on 6-OHDA-induced death in a dopaminergic cell line: Modulation by inhibitors of PI3 kinase and MEK. J. Neurosci. Res. 73, 105-112. (Pubitemid 36791375)
42. Ulery P. G., Beers J., Mikhailenko I., Tanzi R. E., Rebeck G. W., Hyman B. T., and, Strickland D. K., (2000) Modulation of beta-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP). Evidence that LRP contributes to the pathogenesis of Alzheimer's disease. J. Biol. Chem. 275, 7410-7415. (Pubitemid 30146296)
43. Van Uden E., Kang D. E., Koo E. H., and, Masliah E., (2000) LDL receptor-related protein (LRP) in Alzheimer's disease: towards a unified theory of pathogenesis. Microsc. Res. Tech. 50, 268-272. (Pubitemid 30651164)
44. Vana K., Zuber C., Pflanz H., Kolodziejczak D., Zemora G., Bergmann A.-K., and, Weiss S., (2009) LRP/LR as an alternative promising target in therapy of prion diseases, Alzheimer's disease and cancer. Infect. Disord. Drug Targets 9, 69-80.
45. Wallace W. C., Akar C. A., and, Lyons W. E., (1997) Amyloid precursor protein potentiates the neurotrophic activity of NGF. Brain Res. Mol. Brain Res. 52, 201-212. (Pubitemid 28043463)
46. Wang X., Wang Z., Yao Y., Li J., Zhang X., Li C., Cheng Y., Ding G., Liu L., and, Ding Z., (2011) Essential role of ERK activation in neurite outgrowth induced by α-lipoic acid. BBA-Mol. Cell Res. 1813, 827-838.
47. Willnow T. E., (1998) Receptor-associated protein (RAP): a specialized chaperone for endocytic receptors. Biol. chem. 379, 1025-1031. (Pubitemid 28456813)
48. Young-Pearse T. L., Bai J., Chang R., Zheng J. B., LoTurco J. J., and, Selkoe D. J., (2007) A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference. J. Neurosci. 27, 14459-14469.
49. Young-Pearse T. L., Chen A. C., Chang R., Marquez C., and, Selkoe D. J., (2008) Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1. Neural Dev. 3, 15.
50. Zheng H., Jiang M., Trumbauer M. E., et al,. (1995) beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity. Cell 81, 525-531.
51. Zlokovic B. V., Deane R., Sagare A. P., Bell R. D., and, Winkler E. A., (2010) Low-density lipoprotein receptor-related protein-1: a serial clearance homeostatic mechanism controlling Alzheimer's amyloid β-peptide elimination from the brain B. V. Zlokovic et al. LRP1: a key regulator of Aβ homeostasis. J. Neurochem. 115, 1077-1089.