Tandem nucleophilic addition/oxy-2-azonia-cope rearrangement for the formation of homoallylic amides and lactams: Total synthesis and structural verification of motuporamine G

Journal of the American Chemical Society

Volumn 134, Issue 49, 2012, Pages 20009-20012

  Zhou, Lijun ^a,c   Li, Zhiming ^a   Zou, Yue ^c   Wang, Quanrui ^a   Sanhueza, Italo A ^b   Schoenebeck, Franziska ^b   Goeke, Andreas ^c  

^a FUDAN UNIVERSITY   (China)

^b ETH ZURICH   (Switzerland)

^c Givaudan Fragrances (Shanghai) Ltd   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH ENERGY; LEWIS ACID; MACROCYCLICS; NOVEL ROUTE; NUCLEOPHILIC ADDITIONS; RING ENLARGEMENT; STRUCTURAL VERIFICATION; TOTAL SYNTHESIS; TRANSITION STATE; UNSATURATED KETONES; ZWITTERIONIC INTERMEDIATE;

ADDITION REACTIONS; KETONES; NITROGEN COMPOUNDS; STEREOCHEMISTRY;

AMIDES;

ALKALOID DERIVATIVE; CYCLOALKANONE; KETONE DERIVATIVE; LACTAM; MACROCYCLIC COMPOUND; MOTUPORAMINE G; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; EQUILIBRIUM CONSTANT; NUCLEOPHILICITY; STEREOCHEMISTRY; SYNTHESIS;

ALKALOIDS; AMIDES; AZO COMPOUNDS; LACTAMS; MOLECULAR STRUCTURE;

EID: 84870905821     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja310002m     Document Type: Article

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