-
1
-
-
2642616988
-
-
Wäspi, U.; Blanc, D.; Winkler, T.; Ruedi, P.; Dudler, R. Mol. Plant-Microbe Interact. 1998, 11, 727
-
(1998)
Mol. Plant-Microbe Interact.
, vol.11
, pp. 727
-
-
Wäspi, U.1
Blanc, D.2
Winkler, T.3
Ruedi, P.4
Dudler, R.5
-
2
-
-
0032952478
-
-
Wäspi, U.; Hassa, P.; Staempfli, A. A.; Molleyres, L. P.; Winker, T.; Dudler, R. Microbiol. Res. 1999, 154, 89
-
(1999)
Microbiol. Res.
, vol.154
, pp. 89
-
-
Wäspi, U.1
Hassa, P.2
Staempfli, A.A.3
Molleyres, L.P.4
Winker, T.5
Dudler, R.6
-
3
-
-
0035107884
-
-
Wäspi, U.; Schweizer, P.; Dudler, R. Plant Cell 2001, 13, 153
-
(2001)
Plant Cell
, vol.13
, pp. 153
-
-
Wäspi, U.1
Schweizer, P.2
Dudler, R.3
-
4
-
-
33751040506
-
-
Coleman, C. S.; Rocetes, J. P.; Park, D. J.; Wallick, C. J.; Warn-Cramer, B. J.; Michel, K.; Dudler, R.; Bachmann, A. S. Cell Proliferation 2006, 39, 599
-
(2006)
Cell Proliferation
, vol.39
, pp. 599
-
-
Coleman, C.S.1
Rocetes, J.P.2
Park, D.J.3
Wallick, C.J.4
Warn-Cramer, B.J.5
Michel, K.6
Dudler, R.7
Bachmann, A.S.8
-
5
-
-
42049085712
-
-
Groll, M.; Schellenberg, B.; Bachmann, A. S.; Archer, C. R.; Huber, R.; Powell, T. K.; Lindow, S.; Kaiser, M.; Dudler, R. Nature 2008, 452, 755
-
(2008)
Nature
, vol.452
, pp. 755
-
-
Groll, M.1
Schellenberg, B.2
Bachmann, A.S.3
Archer, C.R.4
Huber, R.5
Powell, T.K.6
Lindow, S.7
Kaiser, M.8
Dudler, R.9
-
8
-
-
77955159713
-
-
For a discussion of the proteasome as a target for cancer chemotherapy, see
-
For a discussion of the proteasome as a target for cancer chemotherapy, see
-
-
-
-
12
-
-
14544303662
-
-
Rajkumar, S. V.; Richardson, P. G.; Hideshima, T.; Anderson, K. C. J. Clin. Oncol. 2005, 23, 630
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 630
-
-
Rajkumar, S.V.1
Richardson, P.G.2
Hideshima, T.3
Anderson, K.C.4
-
14
-
-
13844320703
-
-
Chauhan, D.; Hideshima, T.; Anderson, K. C. Annu. Rev. Pharmacol. Toxicol. 2005, 45, 465
-
(2005)
Annu. Rev. Pharmacol. Toxicol.
, vol.45
, pp. 465
-
-
Chauhan, D.1
Hideshima, T.2
Anderson, K.C.3
-
15
-
-
66149090781
-
-
Clerc, J.; Groll, M.; Illich, D. J.; Bachmann, A. S.; Huber, R.; Schellenberg, B.; Dudler, R.; Kaiser, M. Proc. Natl. Acad. Sci. U.S.A. 2009, 106, 6507
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 6507
-
-
Clerc, J.1
Groll, M.2
Illich, D.J.3
Bachmann, A.S.4
Huber, R.5
Schellenberg, B.6
Dudler, R.7
Kaiser, M.8
-
16
-
-
77954756715
-
-
published online May 19, 2010; DOI: 10.1002/ejoc.201000317
-
Clerc, J.; Schellenberg, B.; Groll, M.; Bachmann, A. S.; Huber, R.; Dudler, R.; Kaiser, M. Eur. J. Org. Chem. 2010, published online May 19, 2010; DOI: 10.1002/ejoc.201000317.
-
(2010)
Eur. J. Org. Chem.
-
-
Clerc, J.1
Schellenberg, B.2
Groll, M.3
Bachmann, A.S.4
Huber, R.5
Dudler, R.6
Kaiser, M.7
-
17
-
-
77952328393
-
-
Pirrung, M. C.; Biswas, G.; Ibarra-Rivera, T. R. Org. Lett. 2010, 12, 2402
-
(2010)
Org. Lett.
, vol.12
, pp. 2402
-
-
Pirrung, M.C.1
Biswas, G.2
Ibarra-Rivera, T.R.3
-
20
-
-
77955163060
-
-
The stereochemical integrity of the α-stereogenic center and % ee of 7 were determined by HPLC analysis
-
The stereochemical integrity of the α-stereogenic center and % ee of 7 were determined by HPLC analysis.
-
-
-
-
21
-
-
85023346540
-
-
For seminal studies on the preparation and utility of vinylogous amino acids, see
-
For seminal studies on the preparation and utility of vinylogous amino acids, see: Hagihara, M.; Anthony, N. J.; Stout, T. J.; Clardy, J.; Schreiber, S. L. J. Am. Chem. Soc. 1992, 114, 6568
-
(1992)
J. Am. Chem. Soc.
, vol.114
, pp. 6568
-
-
Hagihara, M.1
Anthony, N.J.2
Stout, T.J.3
Clardy, J.4
Schreiber, S.L.5
-
23
-
-
77955124625
-
-
During the preparation of this manuscript, Kaiser and coworkers described a similar approach to fragment 4; see ref 9b
-
During the preparation of this manuscript, Kaiser and coworkers described a similar approach to fragment 4; see ref 9b.
-
-
-
-
24
-
-
77955149807
-
-
1H NMR
-
1H NMR.
-
-
-
-
25
-
-
77955165599
-
-
Decomposition and epimerization were always observed when handling the aldehyde. In contrast, the carboxylic acid was found to be quite stable and did not undergo noticeable epimerization
-
Decomposition and epimerization were always observed when handling the aldehyde. In contrast, the carboxylic acid was found to be quite stable and did not undergo noticeable epimerization.
-
-
-
-
26
-
-
77955152707
-
-
For an example of the lability of the products of oxidation of vinylglycinol derivatives, see
-
For an example of the lability of the products of oxidation of vinylglycinol derivatives, see
-
-
-
-
27
-
-
0033531354
-
-
Campbell, A. D.; Taylor, R. J. K.; Raynham, T. M. Chem. Commum. 1999, 24, 245
-
(1999)
Chem. Commum.
, vol.24
, pp. 245
-
-
Campbell, A.D.1
Taylor, R.J.K.2
Raynham, T.M.3
-
28
-
-
77955169083
-
-
1H NMR as compared with the coupling of 4 with (±)-α- methylbenzylamine. See Supporting Information for further details
-
1H NMR as compared with the coupling of 4 with (±)-α- methylbenzylamine. See Supporting Information for further details.
-
-
-
-
29
-
-
77955137245
-
-
This intermediate was also prepared in the recently reported synthesis by Pirrung and coworkers using a Horner-Wadsworth-Emmons macrocyclization. See ref 10 for details
-
This intermediate was also prepared in the recently reported synthesis by Pirrung and coworkers using a Horner-Wadsworth-Emmons macrocyclization. See ref 10 for details.
-
-
-
-
30
-
-
77955154785
-
-
Analysis of the crude UPLC-MS data indicated that dimeric and trimeric products are also formed during the formation of the strained 12-membered macrocycle
-
Analysis of the crude UPLC-MS data indicated that dimeric and trimeric products are also formed during the formation of the strained 12-membered macrocycle.
-
-
-
-
31
-
-
77955145780
-
-
The isocyanate was prepared using triphosgene; see
-
The isocyanate was prepared using triphosgene; see
-
-
-
-
32
-
-
25844479168
-
-
Sunder-Plassmann, N.; Sarli, V.; Gartner, M.; Utz, M.; Seiler, J.; Huemmer, S.; Mayer, T. U.; Surrey, T.; Giannis, A. Biorg. Med. Chem. 2005, 13, 6094
-
(2005)
Biorg. Med. Chem.
, vol.13
, pp. 6094
-
-
Sunder-Plassmann, N.1
Sarli, V.2
Gartner, M.3
Utz, M.4
Seiler, J.5
Huemmer, S.6
Mayer, T.U.7
Surrey, T.8
Giannis, A.9
-
34
-
-
77955167597
-
-
note
-
+ 494.2979, found 494.3003.
-
-
-
|