LC-MS in Endogenous Metabolite Profiling and Small-Molecule Biomarker Discovery

Mass Spectrometry in Drug Metabolism and Disposition: Basic Principles and Applications

Volumn , Issue , 2011, Pages 685-722

  Reily, Michael D ^a   Shipkova, Petia ^a   Hnatyshyn, Serhiy ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Data processing and analysis goal of LC MS based metabonomics measured signal conversion into a reproducible pattern for fingerprinting, descriptive of physiological responses; LC MS in endogenous metabolite profiling, and small molecule biomarker discovery deduction, perturbation and effected biochemical pathways, and biomarker discovery; Metabonomics, three approaches fingerprinting, nontargeted metabonomics and targeted metabonomics, with practical utility and unique analytical work flows

Indexed keywords

EID: 84870896374     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470929278.ch21     Document Type: Chapter

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