-
1
-
-
34347222589
-
Roles of epidermal growth factor family in the regulation of postnatal somatic growth
-
Xian, C.J. (2007) Roles of epidermal growth factor family in the regulation of postnatal somatic growth. Endocr. Rev., 28, 284-296.
-
(2007)
Endocr. Rev.
, vol.28
, pp. 284-296
-
-
Xian, C.J.1
-
2
-
-
0027964261
-
Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia
-
Shiang, R., Thompson, L.M., Zhu, Y.Z., Church, D.M., Fielder, T.J., Bocian, M., Winokur, S.T. and Wasmuth, J.J. (1994) Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia. Cell, 78, 335-342.
-
(1994)
Cell
, vol.78
, pp. 335-342
-
-
Shiang, R.1
Thompson, L.M.2
Zhu, Y.Z.3
Church, D.M.4
Fielder, T.J.5
Bocian, M.6
Winokur, S.T.7
Wasmuth, J.J.8
-
3
-
-
0030773251
-
Fibroblast growth factor receptor 3 and the human chondrodysplasias
-
Horton, W.A. (1997) Fibroblast growth factor receptor 3 and the human chondrodysplasias. Curr. Opin. Pediatr., 9, 437-442.
-
(1997)
Curr. Opin. Pediatr.
, vol.9
, pp. 437-442
-
-
Horton, W.A.1
-
4
-
-
0029912958
-
Common mutations in the fibroblast growth factor receptor 3 (FGFR 3) gene account for achondroplasia, hypochondroplasia, and thanatophoric dwarfism
-
Bonaventure, J., Rousseau, F., Legeai-Mallet, L., Le Merrer, M., Munnich, A. and Maroteaux, P. (1996) Common mutations in the fibroblast growth factor receptor 3 (FGFR 3) gene account for achondroplasia, hypochondroplasia, and thanatophoric dwarfism. Am. J. Med. Genet., 63, 148-154.
-
(1996)
Am. J. Med. Genet.
, vol.63
, pp. 148-154
-
-
Bonaventure, J.1
Rousseau, F.2
Legeai-Mallet, L.3
Le Merrer, M.4
Munnich, A.5
Maroteaux, P.6
-
5
-
-
0029937714
-
Missense FGFR3 mutations create cysteine residues in thanatophoric dwarfism type I (TD1)
-
Rousseau, F., el Ghouzzi, V., Delezoide, A.L., Legeai-Mallet, L., Le Merrer, M., Munnich, A. and Bonaventure, J. (1996) Missense FGFR3 mutations create cysteine residues in thanatophoric dwarfism type I (TD1). Hum. Mol. Genet., 5, 509-512.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 509-512
-
-
Rousseau, F.1
el Ghouzzi, V.2
Delezoide, A.L.3
Legeai-Mallet, L.4
Le Merrer, M.5
Munnich, A.6
Bonaventure, J.7
-
6
-
-
33751082112
-
A novel mutation in FGFR3 causes camptodactyly, tall stature, and hearing loss (CATSHL) syndrome
-
Toydemir, R.M., Brassington, A.E., Bayrak-Toydemir, P., Krakowiak, P.A., Jorde, L.B., Whitby, F.G., Longo, N., Viskochil, D.H., Carey, J.C. and Bamshad, M.J. (2006) A novel mutation in FGFR3 causes camptodactyly, tall stature, and hearing loss (CATSHL) syndrome. Am. J. Hum. Genet., 79, 935-941.
-
(2006)
Am. J. Hum. Genet.
, vol.79
, pp. 935-941
-
-
Toydemir, R.M.1
Brassington, A.E.2
Bayrak-Toydemir, P.3
Krakowiak, P.A.4
Jorde, L.B.5
Whitby, F.G.6
Longo, N.7
Viskochil, D.H.8
Carey, J.C.9
Bamshad, M.J.10
-
7
-
-
0032413011
-
Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3
-
Naski, M.C., Colvin, J.S., Coffin, J.D. and Ornitz, D.M. (1998) Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3. Development, 125, 4977-4988.
-
(1998)
Development
, vol.125
, pp. 4977-4988
-
-
Naski, M.C.1
Colvin, J.S.2
Coffin, J.D.3
Ornitz, D.M.4
-
8
-
-
0033456159
-
Gly369Cys mutation in mouse FGFR3 causes achondroplasia by affecting both chondrogenesis and osteogenesis
-
Chen, L., Adar, R., Yang, X., Monsonego, E.O., Li, C., Hauschka, P.V., Yayon, A. and Deng, C.X. (1999) Gly369Cys mutation in mouse FGFR3 causes achondroplasia by affecting both chondrogenesis and osteogenesis. J. Clin. Invest., 104, 1517-1525.
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 1517-1525
-
-
Chen, L.1
Adar, R.2
Yang, X.3
Monsonego, E.O.4
Li, C.5
Hauschka, P.V.6
Yayon, A.7
Deng, C.X.8
-
9
-
-
0037097976
-
FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease
-
Ornitz, D.M. and Marie, P.J. (2002) FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease. Genes. Dev., 16, 1446-1465.
-
(2002)
Genes. Dev.
, vol.16
, pp. 1446-1465
-
-
Ornitz, D.M.1
Marie, P.J.2
-
10
-
-
0032938128
-
A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors
-
Li, C., Chen, L., Iwata, T., Kitagawa, M., Fu, X.Y. and Deng, C.X. (1999) A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors. Hum. Mol. Genet., 8, 35-44.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 35-44
-
-
Li, C.1
Chen, L.2
Iwata, T.3
Kitagawa, M.4
Fu, X.Y.5
Deng, C.X.6
-
11
-
-
0030896404
-
Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism
-
Su, W.C., Kitagawa, M., Xue, N., Xie, B., Garofalo, S., Cho, J., Deng, C., Horton, W.A. and Fu, X.Y. (1997) Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism. Nature, 386, 288-292.
-
(1997)
Nature
, vol.386
, pp. 288-292
-
-
Su, W.C.1
Kitagawa, M.2
Xue, N.3
Xie, B.4
Garofalo, S.5
Cho, J.6
Deng, C.7
Horton, W.A.8
Fu, X.Y.9
-
12
-
-
0033151612
-
FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway
-
Sahni, M., Ambrosetti, D.C., Mansukhani, A., Gertner, R., Levy, D. and Basilico, C. (1999) FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway. Genes. Dev., 13, 1361-1366.
-
(1999)
Genes. Dev.
, vol.13
, pp. 1361-1366
-
-
Sahni, M.1
Ambrosetti, D.C.2
Mansukhani, A.3
Gertner, R.4
Levy, D.5
Basilico, C.6
-
13
-
-
1042289662
-
Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype
-
Murakami, S., Balmes, G., McKinney, S., Zhang, Z., Givol, D. and de Crombrugghe, B. (2004) Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype. Genes. Dev., 18, 290-305.
-
(2004)
Genes. Dev.
, vol.18
, pp. 290-305
-
-
Murakami, S.1
Balmes, G.2
McKinney, S.3
Zhang, Z.4
Givol, D.5
de Crombrugghe, B.6
-
14
-
-
0033951768
-
FGFs, heparan sulfate and FGFRs: complex interactions essential for development
-
Ornitz, D.M. (2000) FGFs, heparan sulfate and FGFRs: complex interactions essential for development. Bioessays, 22, 108-112.
-
(2000)
Bioessays
, vol.22
, pp. 108-112
-
-
Ornitz, D.M.1
-
15
-
-
66349135677
-
Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice
-
Qing, J., Du, X., Chen, Y., Chan, P., Li, H., Wu, P., Marsters, S., Stawicki, S., Tien, J., Totpal, K. et al. (2009) Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice. J. Clin. Invest., 119, 1216-1229.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1216-1229
-
-
Qing, J.1
Du, X.2
Chen, Y.3
Chan, P.4
Li, H.5
Wu, P.6
Marsters, S.7
Stawicki, S.8
Tien, J.9
Totpal, K.10
-
16
-
-
0035815704
-
A novel alternatively spliced fibroblast growth factor receptor 3 isoform lacking the acid box domain is expressed during chondrogenic differentiation of ATDC5 cells
-
Shimizu, A., Tada, K., Shukunami, C., Hiraki, Y., Kurokawa, T., Magane, N. and Kurokawa-Seo, M. (2001) A novel alternatively spliced fibroblast growth factor receptor 3 isoform lacking the acid box domain is expressed during chondrogenic differentiation of ATDC5 cells. J. Biol. Chem., 276, 11031-11040.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 11031-11040
-
-
Shimizu, A.1
Tada, K.2
Shukunami, C.3
Hiraki, Y.4
Kurokawa, T.5
Magane, N.6
Kurokawa-Seo, M.7
-
17
-
-
33845439885
-
Ascorbate-enhanced chondrogenesis of ATDC5 cells
-
64-69; discussion
-
Altaf, F.M., Hering, T.M., Kazmi, N.H., Yoo, J.U. and Johnstone, B. (2006) Ascorbate-enhanced chondrogenesis of ATDC5 cells. Eur. Cell Mater., 12, 64-69; discussion 69-70.
-
(2006)
Eur. Cell Mater.
, vol.12
, pp. 69-70
-
-
Altaf, F.M.1
Hering, T.M.2
Kazmi, N.H.3
Yoo, J.U.4
Johnstone, B.5
-
18
-
-
0034234569
-
A neonatal lethal mutation in FGFR3 uncouples proliferation and differentiation of growth plate chondrocytes in embryos
-
Iwata, T., Chen, L., Li, C., Ovchinnikov, D.A., Behringer, R.R., Francomano, C.A. and Deng, C.X. (2000) A neonatal lethal mutation in FGFR3 uncouples proliferation and differentiation of growth plate chondrocytes in embryos. Hum. Mol. Genet., 9, 1603-1613.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 1603-1613
-
-
Iwata, T.1
Chen, L.2
Li, C.3
Ovchinnikov, D.A.4
Behringer, R.R.5
Francomano, C.A.6
Deng, C.X.7
-
19
-
-
0028093135
-
Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia
-
Rousseau, F., Bonaventure, J., Legeai-Mallet, L., Pelet, A., Rozet, J.M., Maroteaux, P., Le Merrer, M. and Munnich, A. (1994) Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia. Nature, 371, 252-254.
-
(1994)
Nature
, vol.371
, pp. 252-254
-
-
Rousseau, F.1
Bonaventure, J.2
Legeai-Mallet, L.3
Pelet, A.4
Rozet, J.M.5
Maroteaux, P.6
Le Merrer, M.7
Munnich, A.8
-
20
-
-
0028890851
-
Achondroplasia is defined by recurrent G380R mutations of FGFR3
-
Bellus, G.A., Hefferon, T.W., Ortiz de Luna, R.I., Hecht, J.T., Horton, W.A., Machado, M., Kaitila, I., McIntosh, I. and Francomano, C.A. (1995) Achondroplasia is defined by recurrent G380R mutations of FGFR3. Am. J. Hum. Genet., 56, 368-373.
-
(1995)
Am. J. Hum. Genet.
, vol.56
, pp. 368-373
-
-
Bellus, G.A.1
Hefferon, T.W.2
Ortiz de Luna, R.I.3
Hecht, J.T.4
Horton, W.A.5
Machado, M.6
Kaitila, I.7
McIntosh, I.8
Francomano, C.A.9
-
21
-
-
0032774475
-
Clinical spectrum of fibroblast growth factor receptor mutations
-
Passos-Bueno, M.R., Wilcox, W.R., Jabs, E.W., Sertie, A.L., Alonso, L.G. and Kitoh, H. (1999) Clinical spectrum of fibroblast growth factor receptor mutations. Hum. Mutat., 14, 115-125.
-
(1999)
Hum. Mutat.
, vol.14
, pp. 115-125
-
-
Passos-Bueno, M.R.1
Wilcox, W.R.2
Jabs, E.W.3
Sertie, A.L.4
Alonso, L.G.5
Kitoh, H.6
-
22
-
-
0028872752
-
Thanatophoric dysplasia (types I and II) caused by distinct mutations in fibroblast growth factor receptor 3
-
Tavormina, P.L., Shiang, R., Thompson, L.M., Zhu, Y.Z., Wilkin, D.J., Lachman, R.S., Wilcox, W.R., Rimoin, D.L., Cohn, D.H. and Wasmuth, J.J. (1995) Thanatophoric dysplasia (types I and II) caused by distinct mutations in fibroblast growth factor receptor 3. Nat. Genet., 9, 321-328.
-
(1995)
Nat. Genet.
, vol.9
, pp. 321-328
-
-
Tavormina, P.L.1
Shiang, R.2
Thompson, L.M.3
Zhu, Y.Z.4
Wilkin, D.J.5
Lachman, R.S.6
Wilcox, W.R.7
Rimoin, D.L.8
Cohn, D.H.9
Wasmuth, J.J.10
-
23
-
-
0029794956
-
Short-term recombinant human growth hormone treatment increases growth rate in achondroplasia
-
Shohat, M., Tick, D., Barakat, S., Bu, X., Melmed, S. and Rimoin, D.L. (1996) Short-term recombinant human growth hormone treatment increases growth rate in achondroplasia. J. Clin. Endocrinol. Metab., 81, 4033-4037.
-
(1996)
J. Clin. Endocrinol. Metab.
, vol.81
, pp. 4033-4037
-
-
Shohat, M.1
Tick, D.2
Barakat, S.3
Bu, X.4
Melmed, S.5
Rimoin, D.L.6
-
24
-
-
0030928105
-
Growth and growth hormone therapy in children with achondroplasia: a two-year experience
-
Stamoyannou, L., Karachaliou, F., Neou, P., Papataxiarchou, K., Pistevos, G. and Bartsocas, C.S. (1997) Growth and growth hormone therapy in children with achondroplasia: a two-year experience. Am. J. Med. Genet., 72, 71-76.
-
(1997)
Am. J. Med. Genet.
, vol.72
, pp. 71-76
-
-
Stamoyannou, L.1
Karachaliou, F.2
Neou, P.3
Papataxiarchou, K.4
Pistevos, G.5
Bartsocas, C.S.6
-
25
-
-
0030020454
-
Human growth hormone treatment in prepubertal children with achondroplasia
-
Weber, G., Prinster, C., Meneghel, M., Russo, F., Mora, S., Puzzovio, M., Del Maschio, M. and Chiumello, G. (1996) Human growth hormone treatment in prepubertal children with achondroplasia. Am. J. Med. Genet., 61, 396-400.
-
(1996)
Am. J. Med. Genet.
, vol.61
, pp. 396-400
-
-
Weber, G.1
Prinster, C.2
Meneghel, M.3
Russo, F.4
Mora, S.5
Puzzovio, M.6
Del Maschio, M.7
Chiumello, G.8
-
26
-
-
0034909417
-
Limb lengthening in short stature patients
-
Aldegheri, R. and Dall'Oca, C. (2001) Limb lengthening in short stature patients. J. Pediatr. Orthop. B, 10, 238-247.
-
(2001)
J. Pediatr. Orthop. B
, vol.10
, pp. 238-247
-
-
Aldegheri, R.1
Dall'Oca, C.2
-
27
-
-
0023841755
-
Lengthening of the lower limbs in achondroplastic patients. A comparative study of four techniques
-
Aldegheri, R., Trivella, G., Renzi-Brivio, L., Tessari, G., Agostini, S. and Lavini, F. (1988) Lengthening of the lower limbs in achondroplastic patients. A comparative study of four techniques. J. Bone Joint Surg. Br., 70, 69-73.
-
(1988)
J. Bone Joint Surg. Br.
, vol.70
, pp. 69-73
-
-
Aldegheri, R.1
Trivella, G.2
Renzi-Brivio, L.3
Tessari, G.4
Agostini, S.5
Lavini, F.6
-
28
-
-
0037861955
-
Fibroblast growth factor receptor-3 as a therapeutic target for Achondroplasia-genetic short limbed dwarfism
-
Aviezer, D., Golembo, M. and Yayon, A. (2003) Fibroblast growth factor receptor-3 as a therapeutic target for Achondroplasia-genetic short limbed dwarfism. Curr. Drug Targets, 4, 353-365.
-
(2003)
Curr. Drug Targets
, vol.4
, pp. 353-365
-
-
Aviezer, D.1
Golembo, M.2
Yayon, A.3
-
29
-
-
11144358656
-
Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathway
-
Yasoda, A., Komatsu, Y., Chusho, H., Miyazawa, T., Ozasa, A., Miura, M., Kurihara, T., Rogi, T., Tanaka, S., Suda, M. et al. (2004) Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathway. Nat. Med., 10, 80-86.
-
(2004)
Nat. Med.
, vol.10
, pp. 80-86
-
-
Yasoda, A.1
Komatsu, Y.2
Chusho, H.3
Miyazawa, T.4
Ozasa, A.5
Miura, M.6
Kurihara, T.7
Rogi, T.8
Tanaka, S.9
Suda, M.10
-
30
-
-
20444414924
-
Complementary antagonistic actions between C-type natriuretic peptide and the MAPK pathway through FGFR-3 in ATDC5 cells
-
Ozasa, A., Komatsu, Y., Yasoda, A., Miura, M., Sakuma, Y., Nakatsuru, Y., Arai, H., Itoh, N. and Nakao, K. (2005) Complementary antagonistic actions between C-type natriuretic peptide and the MAPK pathway through FGFR-3 in ATDC5 cells. Bone, 36, 1056-1064.
-
(2005)
Bone
, vol.36
, pp. 1056-1064
-
-
Ozasa, A.1
Komatsu, Y.2
Yasoda, A.3
Miura, M.4
Sakuma, Y.5
Nakatsuru, Y.6
Arai, H.7
Itoh, N.8
Nakao, K.9
-
31
-
-
0035263614
-
A Ser(365)- Cys mutation of fibroblast growth factor receptor 3 in mouse downregulates Ihh/PTHrP signals and causes severe achondroplasia
-
Chen, L., Li, C., Qiao, W., Xu, X. and Deng, C. (2001) A Ser(365)-Cys mutation of fibroblast growth factor receptor 3 in mouse downregulates Ihh/PTHrP signals and causes severe achondroplasia. Hum. Mol. Genet., 10, 457-465.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 457-465
-
-
Chen, L.1
Li, C.2
Qiao, W.3
Xu, X.4
Deng, C.5
-
32
-
-
0036198395
-
Human PTH (1-34) induces longitudinal bone growth in rats
-
Ogawa, T., Yamagiwa, H., Hayami, T., Liu, Z., Huang, K.Y., Tokunaga, K., Murai, T. and Endo, N. (2002) Human PTH (1-34) induces longitudinal bone growth in rats. J. Bone Miner. Metab., 20, 83-90.
-
(2002)
J. Bone Miner. Metab.
, vol.20
, pp. 83-90
-
-
Ogawa, T.1
Yamagiwa, H.2
Hayami, T.3
Liu, Z.4
Huang, K.Y.5
Tokunaga, K.6
Murai, T.7
Endo, N.8
-
33
-
-
34250018251
-
PTH has the potential to rescue disturbed bone growth in achondroplasia
-
Ueda, K., Yamanaka, Y., Harada, D., Yamagami, E., Tanaka, H. and Seino, Y. (2007) PTH has the potential to rescue disturbed bone growth in achondroplasia. Bone, 41, 13-18.
-
(2007)
Bone
, vol.41
, pp. 13-18
-
-
Ueda, K.1
Yamanaka, Y.2
Harada, D.3
Yamagami, E.4
Tanaka, H.5
Seino, Y.6
-
34
-
-
34548371795
-
RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis
-
Shukla, V., Coumoul, X., Wang, R.H., Kim, H.S. and Deng, C.X. (2007) RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis. Nat. Genet., 39, 1145-1150.
-
(2007)
Nat. Genet.
, vol.39
, pp. 1145-1150
-
-
Shukla, V.1
Coumoul, X.2
Wang, R.H.3
Kim, H.S.4
Deng, C.X.5
-
35
-
-
22244488749
-
Oral delivery of peptide drugs: barriers and developments
-
Hamman, J.H., Enslin, G.M. and Kotze, A.F. (2005) Oral delivery of peptide drugs: barriers and developments. BioDrugs, 19, 165-177.
-
(2005)
BioDrugs
, vol.19
, pp. 165-177
-
-
Hamman, J.H.1
Enslin, G.M.2
Kotze, A.F.3
-
36
-
-
28044461993
-
Strategies to improve oral drug bioavailability
-
Gomez-Orellana, I. (2005) Strategies to improve oral drug bioavailability. Expert Opin. Drug Deliv., 2, 419-433.
-
(2005)
Expert Opin. Drug Deliv.
, vol.2
, pp. 419-433
-
-
Gomez-Orellana, I.1
-
37
-
-
0034921323
-
Immunogenicity of well-characterized synthetic Plasmodium falciparum multiple antigen peptide conjugates
-
Joshi, M.B., Gam, A.A., Boykins, R.A., Kumar, S., Sacci, J., Hoffman, S.L., Nakhasi, H.L. and Kenney, R.T. (2001) Immunogenicity of well-characterized synthetic Plasmodium falciparum multiple antigen peptide conjugates. Infect. Immun., 69, 4884-4890.
-
(2001)
Infect. Immun.
, vol.69
, pp. 4884-4890
-
-
Joshi, M.B.1
Gam, A.A.2
Boykins, R.A.3
Kumar, S.4
Sacci, J.5
Hoffman, S.L.6
Nakhasi, H.L.7
Kenney, R.T.8
-
38
-
-
0031596591
-
Efficacy of thymosin alpha1 in patients with chronic hepatitis B: a randomized, controlled trial
-
Chien, R.N., Liaw, Y.F., Chen, T.C., Yeh, C.T. and Sheen, I.S. (1998) Efficacy of thymosin alpha1 in patients with chronic hepatitis B: a randomized, controlled trial. Hepatology, 27, 1383-1387.
-
(1998)
Hepatology
, vol.27
, pp. 1383-1387
-
-
Chien, R.N.1
Liaw, Y.F.2
Chen, T.C.3
Yeh, C.T.4
Sheen, I.S.5
-
39
-
-
0029880651
-
Toward cell-targeting gene therapy vectors: selection of cell-binding peptides from random peptide-presenting phage libraries
-
Barry, M.A., Dower, W.J. and Johnston, S.A. (1996) Toward cell-targeting gene therapy vectors: selection of cell-binding peptides from random peptide-presenting phage libraries. Nat. Med., 2, 299-305.
-
(1996)
Nat. Med.
, vol.2
, pp. 299-305
-
-
Barry, M.A.1
Dower, W.J.2
Johnston, S.A.3
-
40
-
-
0025112794
-
Searching for peptide ligands with an epitope library
-
Scott, J.K. and Smith, G.P. (1990) Searching for peptide ligands with an epitope library. Science, 249, 386-390.
-
(1990)
Science
, vol.249
, pp. 386-390
-
-
Scott, J.K.1
Smith, G.P.2
-
41
-
-
0032557555
-
Fibroblast growth factor receptor 3 mutations promote apoptosis but do not alter chondrocyte proliferation in thanatophoric dysplasia
-
Legeai-Mallet, L., Benoist-Lasselin, C., Delezoide, A.L., Munnich, A. and Bonaventure, J. (1998) Fibroblast growth factor receptor 3 mutations promote apoptosis but do not alter chondrocyte proliferation in thanatophoric dysplasia. J. Biol. Chem., 273, 13007-13014.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13007-13014
-
-
Legeai-Mallet, L.1
Benoist-Lasselin, C.2
Delezoide, A.L.3
Munnich, A.4
Bonaventure, J.5
-
42
-
-
14644394929
-
Cell responses to FGFR3 signalling: growth, differentiation and apoptosis
-
L'Hote, C.G. and Knowles, M.A. (2005) Cell responses to FGFR3 signalling: growth, differentiation and apoptosis. Exp. Cell Res., 304, 417-431.
-
(2005)
Exp. Cell Res.
, vol.304
, pp. 417-431
-
-
L'Hote, C.G.1
Knowles, M.A.2
-
43
-
-
38449096256
-
FGF signaling: its role in bone development and human skeleton diseases
-
Su, N., Du, X. and Chen, L. (2008) FGF signaling: its role in bone development and human skeleton diseases. Front. Biosci., 13, 2842-2865.
-
(2008)
Front. Biosci.
, vol.13
, pp. 2842-2865
-
-
Su, N.1
Du, X.2
Chen, L.3
-
44
-
-
0029917507
-
Fibroblast growth factor receptor 3 is a negative regulator of bone growth
-
Deng, C., Wynshaw-Boris, A., Zhou, F., Kuo, A. and Leder, P. (1996) Fibroblast growth factor receptor 3 is a negative regulator of bone growth. Cell, 84, 911-921.
-
(1996)
Cell
, vol.84
, pp. 911-921
-
-
Deng, C.1
Wynshaw-Boris, A.2
Zhou, F.3
Kuo, A.4
Leder, P.5
-
45
-
-
0029928791
-
Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3
-
Colvin, J.S., Bohne, B.A., Harding, G.W., McEwen, D.G. and Ornitz, D.M. (1996) Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3. Nat. Genet., 12, 390-397.
-
(1996)
Nat. Genet.
, vol.12
, pp. 390-397
-
-
Colvin, J.S.1
Bohne, B.A.2
Harding, G.W.3
McEwen, D.G.4
Ornitz, D.M.5
-
46
-
-
0030922231
-
Frequent translocation t(4;14)(p16 3;q32. 3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3
-
Chesi, M., Nardini, E., Brents, L.A., Schrock, E., Ried, T., Kuehl, W.M. and Bergsagel, P.L. (1997) Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3. Nat. Genet., 16, 260-264.
-
(1997)
Nat. Genet.
, vol.16
, pp. 260-264
-
-
Chesi, M.1
Nardini, E.2
Brents, L.A.3
Schrock, E.4
Ried, T.5
Kuehl, W.M.6
Bergsagel, P.L.7
-
47
-
-
0034888840
-
Analysis of FGFR3 gene mutations in multiple myeloma patients with t(4;14)
-
Intini, D., Baldini, L., Fabris, S., Lombardi, L., Ciceri, G., Maiolo, A.T. and Neri, A. (2001) Analysis of FGFR3 gene mutations in multiple myeloma patients with t(4;14). Br. J. Haematol., 114, 362-364.
-
(2001)
Br. J. Haematol.
, vol.114
, pp. 362-364
-
-
Intini, D.1
Baldini, L.2
Fabris, S.3
Lombardi, L.4
Ciceri, G.5
Maiolo, A.T.6
Neri, A.7
-
48
-
-
0032841519
-
Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas
-
Cappellen, D., De Oliveira, C., Ricol, D., de Medina, S., Bourdin, J., Sastre-Garau, X., Chopin, D., Thiery, J.P. and Radvanyi, F. (1999) Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas. Nat. Genet., 23, 18-20.
-
(1999)
Nat. Genet.
, vol.23
, pp. 18-20
-
-
Cappellen, D.1
De Oliveira, C.2
Ricol, D.3
de Medina, S.4
Bourdin, J.5
Sastre-Garau, X.6
Chopin, D.7
Thiery, J.P.8
Radvanyi, F.9
-
49
-
-
67349105009
-
FGFR3 mutations in prostate cancer: association with low-grade tumors
-
Hernandez, S., de Muga, S., Agell, L., Juanpere, N., Esgueva, R., Lorente, J.A., Mojal, S., Serrano, S. and Lloreta, J. (2009) FGFR3 mutations in prostate cancer: association with low-grade tumors. Mod. Pathol., 22, 848-856.
-
(2009)
Mod. Pathol.
, vol.22
, pp. 848-856
-
-
Hernandez, S.1
de Muga, S.2
Agell, L.3
Juanpere, N.4
Esgueva, R.5
Lorente, J.A.6
Mojal, S.7
Serrano, S.8
Lloreta, J.9
-
50
-
-
16944367030
-
A unique point mutation in the fibroblast growth factor receptor 3 gene (FGFR3) defines a new craniosynostosis syndrome
-
Muenke, M., Gripp, K.W., McDonald-McGinn, D.M., Gaudenz, K., Whitaker, L.A., Bartlett, S.P., Markowitz, R.I., Robin, N.H., Nwokoro, N., Mulvihill, J.J. et al. (1997) A unique point mutation in the fibroblast growth factor receptor 3 gene (FGFR3) defines a new craniosynostosis syndrome. Am. J. Hum. Genet., 60, 555-564.
-
(1997)
Am. J. Hum. Genet.
, vol.60
, pp. 555-564
-
-
Muenke, M.1
Gripp, K.W.2
McDonald-McGinn, D.M.3
Gaudenz, K.4
Whitaker, L.A.5
Bartlett, S.P.6
Markowitz, R.I.7
Robin, N.H.8
Nwokoro, N.9
Mulvihill, J.J.10
-
51
-
-
33746754183
-
Mosaicism of activating FGFR3 mutations in human skin causes epidermal nevi
-
Hafner, C., van Oers, J.M., Vogt, T., Landthaler, M., Stoehr, R., Blaszyk, H., Hofstaedter, F., Zwarthoff, E.C. and Hartmann, A. (2006) Mosaicism of activating FGFR3 mutations in human skin causes epidermal nevi. J. Clin. Invest., 116, 2201-2207.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2201-2207
-
-
Hafner, C.1
van Oers, J.M.2
Vogt, T.3
Landthaler, M.4
Stoehr, R.5
Blaszyk, H.6
Hofstaedter, F.7
Zwarthoff, E.C.8
Hartmann, A.9
-
52
-
-
60449111332
-
FGFR3 and PIK3CA mutations are involved in the molecular pathogenesis of solar lentigo
-
Hafner, C., Stoehr, R., van Oers, J.M., Zwarthoff, E.C., Hofstaedter, F., Landthaler, M., Hartmann, A. and Vogt, T. (2009) FGFR3 and PIK3CA mutations are involved in the molecular pathogenesis of solar lentigo. Br. J. Dermatol., 160, 546-551.
-
(2009)
Br. J. Dermatol.
, vol.160
, pp. 546-551
-
-
Hafner, C.1
Stoehr, R.2
van Oers, J.M.3
Zwarthoff, E.C.4
Hofstaedter, F.5
Landthaler, M.6
Hartmann, A.7
Vogt, T.8
-
53
-
-
70350646899
-
Activating mutations in FGFR3 and HRAS reveal a shared genetic origin for congenital disorders and testicular tumors
-
Goriely, A., Hansen, R.M., Taylor, I.B., Olesen, I.A., Jacobsen, G.K., McGowan, S.J., Pfeifer, S.P., McVean, G.A., Rajpert-De Meyts, E. and Wilkie, A.O. (2009) Activating mutations in FGFR3 and HRAS reveal a shared genetic origin for congenital disorders and testicular tumors. Nat. Genet., 41, 1247-1252.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1247-1252
-
-
Goriely, A.1
Hansen, R.M.2
Taylor, I.B.3
Olesen, I.A.4
Jacobsen, G.K.5
McGowan, S.J.6
Pfeifer, S.P.7
McVean, G.A.8
Rajpert-De Meyts, E.9
Wilkie, A.O.10
-
54
-
-
77952523094
-
Gain-of-function mutation in FGFR3 in mice leads to decreased bone mass by affecting both osteoblastogenesis and osteoclastogenesis
-
Su, N., Sun, Q., Li, C., Lu, X., Qi, H., Chen, S., Yang, J., Du, X., Zhao, L., He, Q. et al. (2010) Gain-of-function mutation in FGFR3 in mice leads to decreased bone mass by affecting both osteoblastogenesis and osteoclastogenesis. Hum. Mol. Genet., 19, 1199-1210.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 1199-1210
-
-
Su, N.1
Sun, Q.2
Li, C.3
Lu, X.4
Qi, H.5
Chen, S.6
Yang, J.7
Du, X.8
Zhao, L.9
He, Q.10
-
55
-
-
0029875398
-
Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor
-
Shukunami, C., Shigeno, C., Atsumi, T., Ishizeki, K., Suzuki, F. and Hiraki, Y. (1996) Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor. J. Cell Biol., 133, 457-468.
-
(1996)
J. Cell Biol.
, vol.133
, pp. 457-468
-
-
Shukunami, C.1
Shigeno, C.2
Atsumi, T.3
Ishizeki, K.4
Suzuki, F.5
Hiraki, Y.6
-
56
-
-
33646789792
-
Novel early target genes of parathyroid hormone-related peptide in chondrocytes
-
Hoogendam, J., Parlevliet, E., Miclea, R., Lowik, C.W., Wit, J.M. and Karperien, M. (2006) Novel early target genes of parathyroid hormone-related peptide in chondrocytes. Endocrinology, 147, 3141-3152.
-
(2006)
Endocrinology
, vol.147
, pp. 3141-3152
-
-
Hoogendam, J.1
Parlevliet, E.2
Miclea, R.3
Lowik, C.W.4
Wit, J.M.5
Karperien, M.6
-
57
-
-
0022552896
-
Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue
-
Farndale, R.W., Buttle, D.J. and Barrett, A.J. (1986) Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim. Biophys. Acta, 883, 173-177.
-
(1986)
Biochim. Biophys. Acta
, vol.883
, pp. 173-177
-
-
Farndale, R.W.1
Buttle, D.J.2
Barrett, A.J.3
-
58
-
-
0030008349
-
Efficient in vivo manipulation of mouse genomic sequences at the zygote stage
-
Lakso, M., Pichel, J.G., Gorman, J.R., Sauer, B., Okamoto, Y., Lee, E., Alt, F.W. and Westphal, H. (1996) Efficient in vivo manipulation of mouse genomic sequences at the zygote stage. Proc. Natl Acad. Sci. USA, 93, 5860-5865.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 5860-5865
-
-
Lakso, M.1
Pichel, J.G.2
Gorman, J.R.3
Sauer, B.4
Okamoto, Y.5
Lee, E.6
Alt, F.W.7
Westphal, H.8
-
59
-
-
0019126423
-
Differential staining of cartilage and bone in whole mouse fetuses by Alcian blue and alizarin red S
-
McLeod, M.J. (1980) Differential staining of cartilage and bone in whole mouse fetuses by Alcian blue and alizarin red S. Teratology, 22, 299-301.
-
(1980)
Teratology
, vol.22
, pp. 299-301
-
-
McLeod, M.J.1
|