A highly sensitive isotope-coded derivatization method and its application for the mass spectrometric analysis of analytes containing the carboxyl group

Analytica Chimica Acta

Volumn 758, Issue , 2013, Pages 114-121

  Leng, Jiapeng ^a   Wang, Haoyang ^a   Zhang, Li ^a   Zhang, Jing ^a   Wang, Hang ^a   Guo, Yinlong ^a  

^a SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

Author keywords

Carboxyl group; Chemical derivatization; Isotope labeling; Mass spectrometry

Indexed keywords

ANALYTES; CARBODIIMIDE CHEMISTRY; CARBOXYL GROUPS; CHEMICAL DERIVATIZATION; DERIVATIZATION METHOD; DERIVATIZATIONS; FAST LABELING; FRAGMENT IONS; FREE FATTY ACID; GAS-PHASE HYDROGENATION; GASPHASE; HIGH SENSITIVITY; HUMAN URINE; ISOTOPE LABELING; LABELING REAGENT; LABELING TECHNIQUES; MALDI MS/MS; MASS SPECTROMETRIC ANALYSIS; MS DETECTION; QUANTITATIVE DETERMINATIONS; REACTION MONITORING; TARGET ANALYTES;

CARBOXYLIC ACIDS; IONS; ISOTOPES; MASS SPECTROMETRY; PEPTIDES;

CHEMICAL ANALYSIS;

1,1 DIMETHYL 4 PHENYLPIPERAZINIUM; CARBOXYL GROUP; CARBOXYLIC ACID; CYANAMIDE;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DERIVATIZATION; ELECTROSPRAY MASS SPECTROMETRY; GAS ANALYSIS; HUMAN; HYDROGENATION; HYDROPHOBICITY; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROCESS OPTIMIZATION; QUANTITATIVE ANALYSIS; REACTION ANALYSIS; SENSITIVITY ANALYSIS; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; URINALYSIS;

CARBOXYLIC ACIDS; FATTY ACIDS; HUMANS; ISOTOPE LABELING; LIMIT OF DETECTION; PIPERAZINES; PYRIMIDINES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84870844232     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2012.11.008     Document Type: Article

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