Epigenetic screen of human DNA repair genes identifies aberrant promoter methylation of NEIL1 in head and neck squamous cell carcinoma

Oncogene

Volumn 31, Issue 49, 2012, Pages 5108-5116

  Chaisaingmongkol, J ^a   Popanda, O ^a   Warta, R ^b   Dyckhoff, G ^b   Herpel, E ^c   Geiselhart, L ^a   Claus, R ^a   Lasitschka, F ^c   Campos, B ^b   Oakes, C C ^a   Bermejo, J L ^c   Herold Mende, C ^b   Plass, C ^a   Schmezer, P ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

DNA glycosylase; DNA methylation; HNSCC; NEIL1 expression

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; DNA; DNA GLYCOSYLASE NEIL1; DNA GLYCOSYLTRANSFERASE; DNA METHYLTRANSFERASE 1; MESSENGER RNA; UNCLASSIFIED DRUG;

ARTICLE; CANCER PATIENT; CANCER TISSUE; CONTROLLED STUDY; CPG ISLAND; DIAGNOSTIC TEST ACCURACY STUDY; DNA METHYLATION; DNA REPAIR; EPIGENETICS; FROZEN SECTION; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC SCREENING; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; LASER MICRODISSECTION; MASSARRAY TECHNOLOGY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MICROARRAY; QUANTITATIVE ANALYSIS; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN; TISSUE SECTION; TUMOR CELL LINE;

AGED; AZACITIDINE; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CPG ISLANDS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA GLYCOSYLASES; DNA METHYLATION; DNA REPAIR; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HEAD AND NECK NEOPLASMS; HUMANS; KERATINOCYTES; MALE; MIDDLE AGED; PROMOTER REGIONS, GENETIC; REFERENCE VALUES;

EID: 84870790796     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.660     Document Type: Article

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