-
2
-
-
38049156705
-
Semaphorin regulation of cellular morphology
-
Tran, T.S., Kolodkin, A.L. & Bharadwaj, R. Semaphorin regulation of cellular morphology. Annu. Rev. Cell Dev. Biol. 23, 263-292 (2007).
-
(2007)
Annu. Rev. Cell Dev. Biol.
, vol.23
, pp. 263-292
-
-
Tran, T.S.1
Kolodkin, A.L.2
Bharadwaj, R.3
-
3
-
-
41549099965
-
Semaphorin signaling: Progress made and promises ahead
-
Zhou, Y., Gunput, R.A. & Pasterkamp, R.J. Semaphorin signaling: progress made and promises ahead. Trends Biochem. Sci. 33, 161-170 (2008).
-
(2008)
Trends Biochem. Sci.
, vol.33
, pp. 161-170
-
-
Zhou, Y.1
Gunput, R.A.2
Pasterkamp, R.J.3
-
4
-
-
84857686973
-
Diverse roles for semaphorin-plexin signaling in the immune system
-
Takamatsu, H. & Kumanogoh, A. Diverse roles for semaphorin-plexin signaling in the immune system. Trends Immunol. 33, 127-135 (2012).
-
(2012)
Trends Immunol.
, vol.33
, pp. 127-135
-
-
Takamatsu, H.1
Kumanogoh, A.2
-
5
-
-
84860821068
-
Semaphorin signals tweaking the tumor microenvironment
-
Muratori, C. & Tamagnone, L. Semaphorin signals tweaking the tumor microenvironment. Adv. Cancer Res. 114, 59-85 (2012).
-
(2012)
Adv. Cancer Res.
, vol.114
, pp. 59-85
-
-
Muratori, C.1
Tamagnone, L.2
-
6
-
-
78049406651
-
Structural basis of semaphorin-plexin signalling
-
Janssen, B.J. et al. Structural basis of semaphorin-plexin signalling. Nature 467, 1118-1122 (2010).
-
(2010)
Nature
, vol.467
, pp. 1118-1122
-
-
Janssen, B.J.1
-
7
-
-
78049370988
-
Structural basis for semaphorin signalling through the plexin receptor
-
Nogi, T. et al. Structural basis for semaphorin signalling through the plexin receptor. Nature 467, 1123-1127 (2010).
-
(2010)
Nature
, vol.467
, pp. 1123-1127
-
-
Nogi, T.1
-
8
-
-
0030847193
-
Neuropilin is a receptor for the axonal chemorepellent Semaphorin III
-
He, Z. & Tessier-Lavigne, M. Neuropilin is a receptor for the axonal chemorepellent Semaphorin III. Cell 90, 739-751 (1997).
-
(1997)
Cell
, vol.90
, pp. 739-751
-
-
He, Z.1
Tessier-Lavigne, M.2
-
9
-
-
0030829388
-
Neuropilin is a semaphorin III receptor
-
Kolodkin, A.L. et al. Neuropilin is a semaphorin III receptor. Cell 90, 753-762 (1997).
-
(1997)
Cell
, vol.90
, pp. 753-762
-
-
Kolodkin, A.L.1
-
10
-
-
20244364929
-
Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates
-
Tamagnone, L. et al. Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates. Cell 99, 71-80 (1999).
-
(1999)
Cell
, vol.99
, pp. 71-80
-
-
Tamagnone, L.1
-
11
-
-
0033214312
-
Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors
-
Takahashi, T. et al. Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors. Cell 99, 59-69 (1999).
-
(1999)
Cell
, vol.99
, pp. 59-69
-
-
Takahashi, T.1
-
12
-
-
0032549799
-
Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
-
Soker, S., Takashima, S., Miao, H.Q., Neufeld, G. & Klagsbrun, M. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92, 735-745 (1998).
-
(1998)
Cell
, vol.92
, pp. 735-745
-
-
Soker, S.1
Takashima, S.2
Miao, H.Q.3
Neufeld, G.4
Klagsbrun, M.5
-
13
-
-
0041520529
-
Structure of the semaphorin-3A receptor binding module
-
Antipenko, A. et al. Structure of the semaphorin-3A receptor binding module. Neuron 39, 589-598 (2003).
-
(2003)
Neuron
, vol.39
, pp. 589-598
-
-
Antipenko, A.1
-
14
-
-
0141507038
-
The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D
-
Love, C.A. et al. The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D. Nat. Struct. Biol. 10, 843-848 (2003).
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 843-848
-
-
Love, C.A.1
-
15
-
-
77956216424
-
Structural basis of semaphorin-plexin recognition and viral mimicry from Sema7A and A39R complexes with PlexinC1
-
Liu, H. et al. Structural basis of semaphorin-plexin recognition and viral mimicry from Sema7A and A39R complexes with PlexinC1. Cell 142, 749-761 (2010).
-
(2010)
Cell
, vol.142
, pp. 749-761
-
-
Liu, H.1
-
16
-
-
72149087958
-
Structure and function of the intracellular region of the plexin-b1 transmembrane receptor
-
Tong, Y. et al. Structure and function of the intracellular region of the plexin-b1 transmembrane receptor. J. Biol. Chem. 284, 35962-35972 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 35962-35972
-
-
Tong, Y.1
-
17
-
-
70349453563
-
Crystal structure of the plexin A3 intracellular region reveals an autoinhibited conformation through active site sequestration
-
He, H., Yang, T., Terman, J.R. & Zhang, X. Crystal structure of the plexin A3 intracellular region reveals an autoinhibited conformation through active site sequestration. Proc. Natl. Acad. Sci. USA 106, 15610-15615 (2009).
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 15610-15615
-
-
He, H.1
Yang, T.2
Terman, J.R.3
Zhang, X.4
-
18
-
-
80052339290
-
A dual binding mode for RhoGTPases in plexin signalling
-
Bell, C.H., Aricescu, A.R., Jones, E.Y. & Siebold, C. A dual binding mode for RhoGTPases in plexin signalling. PLoS Biol. 9, e1001134 (2011).
-
(2011)
PLoS Biol.
, vol.9
-
-
Bell, C.H.1
Aricescu, A.R.2
Jones, E.Y.3
Siebold, C.4
-
19
-
-
84856070985
-
Plexins are GTPase-activating proteins for Rap and are activated by induced dimerization
-
Wang, Y. et al. Plexins are GTPase-activating proteins for Rap and are activated by induced dimerization. Sci. Signal. 5, ra6 (2012).
-
(2012)
Sci. Signal.
, vol.5
-
-
Wang, Y.1
-
20
-
-
0032408496
-
Semaphorin-neuropilin interactions underlying sympathetic axon responses to class III semaphorins
-
Chen, H., He, Z., Bagri, A. & Tessier-Lavigne, M. Semaphorin-neuropilin interactions underlying sympathetic axon responses to class III semaphorins. Neuron 21, 1283-1290 (1998).
-
(1998)
Neuron
, vol.21
, pp. 1283-1290
-
-
Chen, H.1
He, Z.2
Bagri, A.3
Tessier-Lavigne, M.4
-
21
-
-
0032215144
-
Neuropilin-2 is a receptor for semaphorin IV: Insight into the structural basis of receptor function and specificity
-
Giger, R.J. et al. Neuropilin-2 is a receptor for semaphorin IV: insight into the structural basis of receptor function and specificity. Neuron 21, 1079-1092 (1998).
-
(1998)
Neuron
, vol.21
, pp. 1079-1092
-
-
Giger, R.J.1
-
22
-
-
0032215735
-
Neuropilin-1 extracellular domains mediate semaphorin D/III-induced growth cone collapse
-
Nakamura, F., Tanaka, M., Takahashi, T., Kalb, R.G. & Strittmatter, S.M. Neuropilin-1 extracellular domains mediate semaphorin D/III-induced growth cone collapse. Neuron 21, 1093-1100 (1998).
-
(1998)
Neuron
, vol.21
, pp. 1093-1100
-
-
Nakamura, F.1
Tanaka, M.2
Takahashi, T.3
Kalb, R.G.4
Strittmatter, S.M.5
-
23
-
-
36549056078
-
Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
-
Appleton, B.A. et al. Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding. EMBO J. 26, 4902-4912 (2007).
-
(2007)
EMBO J.
, vol.26
, pp. 4902-4912
-
-
Appleton, B.A.1
-
24
-
-
72549108629
-
Role of class 3 semaphorins and their receptors in tumor growth and angiogenesis
-
Gaur, P. et al. Role of class 3 semaphorins and their receptors in tumor growth and angiogenesis. Clin. Cancer Res. 15, 6763-6770 (2009).
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 6763-6770
-
-
Gaur, P.1
-
25
-
-
0034191927
-
Plexin/neuropilin complexes mediate repulsion by the axonal guidance signal semaphorin 3A
-
Rohm, B., Ottemeyer, A., Lohrum, M. & Puschel, A.W. Plexin/neuropilin complexes mediate repulsion by the axonal guidance signal semaphorin 3A. Mech. Dev. 93, 95-104 (2000).
-
(2000)
Mech. Dev.
, vol.93
, pp. 95-104
-
-
Rohm, B.1
Ottemeyer, A.2
Lohrum, M.3
Puschel, A.W.4
-
26
-
-
37549050866
-
Semaphorin-3A guides radial migration of cortical neurons during development
-
Chen, G. et al. Semaphorin-3A guides radial migration of cortical neurons during development. Nat. Neurosci. 11, 36-44 (2008).
-
(2008)
Nat. Neurosci.
, vol.11
, pp. 36-44
-
-
Chen, G.1
-
27
-
-
0035105491
-
PlexinA1 autoinhibition by the plexin sema domain
-
Takahashi, T. & Strittmatter, S.M. PlexinA1 autoinhibition by the plexin sema domain. Neuron 29, 429-439 (2001).
-
(2001)
Neuron
, vol.29
, pp. 429-439
-
-
Takahashi, T.1
Strittmatter, S.M.2
-
28
-
-
34447508216
-
Phaser crystallographic software
-
McCoy, A.J. et al. Phaser crystallographic software. J. Appl. Crystallogr. 40, 658-674 (2007).
-
(2007)
J. Appl. Crystallogr.
, vol.40
, pp. 658-674
-
-
McCoy, A.J.1
-
29
-
-
49049093981
-
Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells
-
Toyofuku, T. et al. Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells. Dev. Biol. 321, 251-262 (2008).
-
(2008)
Dev. Biol.
, vol.321
, pp. 251-262
-
-
Toyofuku, T.1
-
30
-
-
0030722135
-
The chemorepulsive activity of secreted semaphorins is regulated by furin-dependent proteolytic processing
-
Adams, R.H., Lohrum, M., Klostermann, A., Betz, H. & Puschel, A.W. The chemorepulsive activity of secreted semaphorins is regulated by furin-dependent proteolytic processing. EMBO J. 16, 6077-6086 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 6077-6086
-
-
Adams, R.H.1
Lohrum, M.2
Klostermann, A.3
Betz, H.4
Puschel, A.W.5
-
31
-
-
77952341533
-
Furin processing of semaphorin 3F determines its anti-angiogenic activity by regulating direct binding and competition for neuropilin
-
Parker, M.W., Hellman, L.M., Xu, P., Fried, M.G. & Vander Kooi, C.W. Furin processing of semaphorin 3F determines its anti-angiogenic activity by regulating direct binding and competition for neuropilin. Biochemistry 49, 4068-4075 (2010).
-
(2010)
Biochemistry
, vol.49
, pp. 4068-4075
-
-
Parker, M.W.1
Hellman, L.M.2
Xu, P.3
Fried, M.G.4
Vander Kooi, C.W.5
-
32
-
-
77951619146
-
A forward genetic screen in mice identifies Sema3A(K108N), which binds to neuropilin-1 but cannot signal
-
Merte, J. et al. A forward genetic screen in mice identifies Sema3A(K108N), which binds to neuropilin-1 but cannot signal. J. Neurosci. 30, 5767-5775 (2010).
-
(2010)
J. Neurosci.
, vol.30
, pp. 5767-5775
-
-
Merte, J.1
-
33
-
-
80054053850
-
Semaphorin 3A lytic hybrid peptide binding to neuropilin-1 as a novel anti-cancer agent in pancreatic cancer
-
Ueyama, H. et al. Semaphorin 3A lytic hybrid peptide binding to neuropilin-1 as a novel anti-cancer agent in pancreatic cancer. Biochem. Biophys. Res. Commun. 414, 60-66 (2011).
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.414
, pp. 60-66
-
-
Ueyama, H.1
-
34
-
-
0032817550
-
Semaphorins as mediators of neuronal apoptosis
-
Shirvan, A. et al. Semaphorins as mediators of neuronal apoptosis. J. Neurochem. 73, 961-971 (1999).
-
(1999)
J. Neurochem.
, vol.73
, pp. 961-971
-
-
Shirvan, A.1
-
35
-
-
0347155577
-
Anti-semaphorin 3A antibodies rescue retinal ganglion cells from cell death following optic nerve axotomy
-
Shirvan, A. et al. Anti-semaphorin 3A antibodies rescue retinal ganglion cells from cell death following optic nerve axotomy. J. Biol. Chem. 277, 49799-49807 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 49799-49807
-
-
Shirvan, A.1
-
36
-
-
0037124068
-
Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165
-
Gu, C. et al. Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165. J. Biol. Chem. 277, 18069-18076 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18069-18076
-
-
Gu, C.1
-
37
-
-
84860501566
-
Osteoprotection by semaphorin 3A
-
Hayashi, M. et al. Osteoprotection by semaphorin 3A. Nature 485, 69-74 (2012).
-
(2012)
Nature
, vol.485
, pp. 69-74
-
-
Hayashi, M.1
-
38
-
-
39449093684
-
Transmembrane domain interactions control biological functions of neuropilin-1
-
Roth, L. et al. Transmembrane domain interactions control biological functions of neuropilin-1. Mol. Biol. Cell 19, 646-654 (2008).
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 646-654
-
-
Roth, L.1
-
39
-
-
33745912405
-
A time-and cost-efficient system for high-level protein production in mammalian cells
-
Aricescu, A.R., Lu, W. & Jones, E.Y. A time-and cost-efficient system for high-level protein production in mammalian cells. Acta Crystallogr. D Biol. Crystallogr. 62, 1243-1250 (2006).
-
(2006)
Acta Crystallogr. D Biol. Crystallogr.
, vol.62
, pp. 1243-1250
-
-
Aricescu, A.R.1
Lu, W.2
Jones, E.Y.3
-
40
-
-
0032924825
-
BirA enzyme: Production and application in the study of membrane receptor-ligand interactions by site-specific biotinylation
-
O'Callaghan, C.A. et al. BirA enzyme: production and application in the study of membrane receptor-ligand interactions by site-specific biotinylation. Anal. Biochem. 266, 9-15 (1999).
-
(1999)
Anal. Biochem.
, vol.266
, pp. 9-15
-
-
O'Callaghan, C.A.1
-
41
-
-
0030886550
-
A 70 amino acid region within the semaphorin domain activates specific cellular response of semaphorin family members
-
Koppel, A.M., Feiner, L., Kobayashi, H. & Raper, J.A. A 70 amino acid region within the semaphorin domain activates specific cellular response of semaphorin family members. Neuron 19, 531-537 (1997).
-
(1997)
Neuron
, vol.19
, pp. 531-537
-
-
Koppel, A.M.1
Feiner, L.2
Kobayashi, H.3
Raper, J.A.4
-
42
-
-
0037109074
-
Structure and function in rhodopsin: High-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line
-
Reeves, P.J., Callewaert, N., Contreras, R. & Khorana, H.G. Structure and function in rhodopsin: high-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N- acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line. Proc. Natl. Acad. Sci. USA 99, 13419-13424 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 13419-13424
-
-
Reeves, P.J.1
Callewaert, N.2
Contreras, R.3
Khorana, H.G.4
-
43
-
-
33847653747
-
Glycoprotein structural genomics: Solving the glycosylation problem
-
Chang, V.T. et al. Glycoprotein structural genomics: solving the glycosylation problem. Structure 15, 267-273 (2007).
-
(2007)
Structure
, vol.15
, pp. 267-273
-
-
Chang, V.T.1
-
44
-
-
23844515485
-
A procedure for setting up high-throughput nanolitre crystallization experiments. Crystallization workflow for initial screening, automated storage, imaging and optimization
-
Walter, T.S. et al. A procedure for setting up high-throughput nanolitre crystallization experiments. Crystallization workflow for initial screening, automated storage, imaging and optimization. Acta Crystallogr. D Biol. Crystallogr. 61, 651-657 (2005).
-
(2005)
Acta Crystallogr. D Biol. Crystallogr.
, vol.61
, pp. 651-657
-
-
Walter, T.S.1
-
45
-
-
13844266400
-
Benefits of automated crystallization plate tracking, imaging, and analysis
-
Mayo, C.J. et al. Benefits of automated crystallization plate tracking, imaging, and analysis. Structure 13, 175-182 (2005).
-
(2005)
Structure
, vol.13
, pp. 175-182
-
-
Mayo, C.J.1
-
47
-
-
0028103275
-
The CCP4 suite: Programs for protein crystallography
-
CCP4
-
CCP4. The CCP4 suite: programs for protein crystallography. Acta Crystallogr. D Biol. Crystallogr. 50, 760-763 (1994).
-
(1994)
Acta Crystallogr. D Biol. Crystallogr.
, vol.50
, pp. 760-763
-
-
-
49
-
-
0030924992
-
Refinement of macromolecular structures by the maximum-likelihood method
-
Murshudov, G.N., Vagin, A.A. & Dodson, E.J. Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr. D Biol. Crystallogr. 53, 240-255 (1997).
-
(1997)
Acta Crystallogr. D Biol. Crystallogr.
, vol.53
, pp. 240-255
-
-
Murshudov, G.N.1
Vagin, A.A.2
Dodson, E.J.3
-
50
-
-
14244272868
-
PHENIX: Building new software for automated crystallographic structure determination
-
Adams, P.D. et al. PHENIX: building new software for automated crystallographic structure determination. Acta Crystallogr. D Biol. Crystallogr. 58, 1948-1954 (2002).
-
(2002)
Acta Crystallogr. D Biol. Crystallogr.
, vol.58
, pp. 1948-1954
-
-
Adams, P.D.1
-
51
-
-
34547592557
-
MolProbity: All-atom contacts and structure validation for proteins and nucleic acids
-
Davis, I.W. et al. MolProbity: all-atom contacts and structure validation for proteins and nucleic acids. Nucleic Acids Res. 35, W375-W383 (2007).
-
(2007)
Nucleic Acids Res.
, vol.35
-
-
Davis, I.W.1
-
52
-
-
3242886771
-
PDB2PQR: An automated pipeline for the setup of Poisson-Boltzmann electrostatics calculations
-
Dolinsky, T.J., Nielsen, J.E., McCammon, J.A. & Baker, N.A. PDB2PQR: an automated pipeline for the setup of Poisson-Boltzmann electrostatics calculations. Nucleic Acids Res. 32, W665-W667 (2004).
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Dolinsky, T.J.1
Nielsen, J.E.2
McCammon, J.A.3
Baker, N.A.4
-
53
-
-
0035964342
-
Electrostatics of nanosystems: Application to microtubules and the ribosome
-
Baker, N.A., Sept, D., Joseph, S., Holst, M.J. & McCammon, J.A. Electrostatics of nanosystems: application to microtubules and the ribosome. Proc. Natl. Acad. Sci. USA 98, 10037-10041 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 10037-10041
-
-
Baker, N.A.1
Sept, D.2
Joseph, S.3
Holst, M.J.4
McCammon, J.A.5
-
54
-
-
36448991500
-
Clustal W and Clustal X version 2
-
Larkin, M.A. et al. Clustal W and Clustal X version 2. Bioinformatics 23, 2947-2948 (2007).
-
(2007)
Bioinformatics
, vol.23
, pp. 2947-2948
-
-
Larkin, M.A.1
-
55
-
-
23144448512
-
ConSurf 2005: The projection of evolutionary conservation scores of residues on protein structures
-
Landau, M. et al. ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures. Nucleic Acids Res. 33, W299-W302 (2005).
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Landau, M.1
-
56
-
-
34548232365
-
Inference of macromolecular assemblies from crystalline state
-
Krissinel, E. & Henrick, K. Inference of macromolecular assemblies from crystalline state. J. Mol. Biol. 372, 774-797 (2007).
-
(2007)
J. Mol. Biol.
, vol.372
, pp. 774-797
-
-
Krissinel, E.1
Henrick, K.2
-
57
-
-
0043122944
-
ExPASy: The proteomics server for in-depth protein knowledge and analysis
-
Gasteiger, E. et al. ExPASy: the proteomics server for in-depth protein knowledge and analysis. Nucleic Acids Res. 31, 3784-3788 (2003).
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 3784-3788
-
-
Gasteiger, E.1
-
58
-
-
34347207265
-
Production of dissociated sensory neuron cultures and considerations for their use in studying neuronal function and plasticity
-
Malin, S.A., Davis, B.M. & Molliver, D.C. Production of dissociated sensory neuron cultures and considerations for their use in studying neuronal function and plasticity. Nat. Protoc. 2, 152-160 (2007).
-
(2007)
Nat. Protoc.
, vol.2
, pp. 152-160
-
-
Malin, S.A.1
Davis, B.M.2
Molliver, D.C.3
-
59
-
-
34548162209
-
The detection and quantification of growth cone collapsing activities
-
Kapfhammer, J.P., Xu, H. & Raper, J.A. The detection and quantification of growth cone collapsing activities. Nat. Protoc. 2, 2005-2011 (2007).
-
(2007)
Nat. Protoc.
, vol.2
, pp. 2005-2011
-
-
Kapfhammer, J.P.1
Xu, H.2
Raper, J.A.3
|