메뉴 건너뛰기




Volumn 39, Issue 6, 2012, Pages 643-652

Haploidentical hematopoietic stem cell transplantation with a megadose T-cell-depleted graft: Harnessing natural and adaptive immunity

Author keywords

[No Author keywords available]

Indexed keywords

ALEMTUZUMAB; CYCLOPHOSPHAMIDE; FLUDARABINE; HLA ANTIGEN; THIOTEPA; THYMOCYTE ANTIBODY;

EID: 84870723622     PISSN: 00937754     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.seminoncol.2012.09.002     Document Type: Article
Times cited : (21)

References (105)
  • 1
    • 54049147312 scopus 로고    scopus 로고
    • Allogeneic stem cell transplantation in acute myeloid leukemia: A risk-adapted approach
    • T. Lodewyck, J.J. Cornelissen Allogeneic stem cell transplantation in acute myeloid leukemia: a risk-adapted approach Blood Rev 22 2008 293 302
    • (2008) Blood Rev , vol.22 , pp. 293-302
    • Lodewyck, T.1    Cornelissen, J.J.2
  • 2
    • 0036036741 scopus 로고    scopus 로고
    • The value of allogeneic bone marrow transplant in patients with acute myeloid leukaemia at differing risk of relapse: Results of the UK MRC AML 10 trial
    • A.K. Burnett, K. Wheatley, A.H. Goldstone The value of allogeneic bone marrow transplant in patients with acute myeloid leukaemia at differing risk of relapse: results of the UK MRC AML 10 trial Br J Haematol 118 2002 385 400
    • (2002) Br J Haematol , vol.118 , pp. 385-400
    • Burnett, A.K.1    Wheatley, K.2    Goldstone, A.H.3
  • 3
    • 0037114753 scopus 로고    scopus 로고
    • Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: Results from Cancer and Leukemia Group B (CALGB 8461)
    • J.C. Byrd, K. Mrozek, R.K. Dodge Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461) Blood 100 2002 4325 4336
    • (2002) Blood , vol.100 , pp. 4325-4336
    • Byrd, J.C.1    Mrozek, K.2    Dodge, R.K.3
  • 4
    • 0025886212 scopus 로고
    • Allogeneic bone marrow transplantation as therapy for primary induction failure for patients with acute leukemia
    • S.J. Forman, G.M. Schmidt, A.P. Nademanee Allogeneic bone marrow transplantation as therapy for primary induction failure for patients with acute leukemia J Clin Oncol 9 1991 1570 1574
    • (1991) J Clin Oncol , vol.9 , pp. 1570-1574
    • Forman, S.J.1    Schmidt, G.M.2    Nademanee, A.P.3
  • 5
    • 0034672165 scopus 로고    scopus 로고
    • Engraftment and survival after unrelated-donor bone marrow transplantation: A report from the national marrow donor program
    • S.M. Davies, C. Kollman, C. Anasetti Engraftment and survival after unrelated-donor bone marrow transplantation: a report from the national marrow donor program Blood 96 2000 4096 4102
    • (2000) Blood , vol.96 , pp. 4096-4102
    • Davies, S.M.1    Kollman, C.2    Anasetti, C.3
  • 6
    • 0030965047 scopus 로고    scopus 로고
    • Results of allogeneic bone marrow transplants for leukemia using donors other than HLA-identical siblings
    • R. Szydlo, J.M. Goldman, J.P. Klein Results of allogeneic bone marrow transplants for leukemia using donors other than HLA-identical siblings J Clin Oncol 15 1997 1767 1777
    • (1997) J Clin Oncol , vol.15 , pp. 1767-1777
    • Szydlo, R.1    Goldman, J.M.2    Klein, J.P.3
  • 7
    • 77954574035 scopus 로고    scopus 로고
    • The impact of HLA genotyping on survival following unrelated donor haematopoietic stem cell transplantation
    • B.E. Shaw, R. Arguello, C.A. Garcia-Sepulveda, J.A. Madrigal The impact of HLA genotyping on survival following unrelated donor haematopoietic stem cell transplantation Br J Haematol 150 2010 251 258
    • (2010) Br J Haematol , vol.150 , pp. 251-258
    • Shaw, B.E.1    Arguello, R.2    Garcia-Sepulveda, C.A.3    Madrigal, J.A.4
  • 8
    • 9244219607 scopus 로고    scopus 로고
    • Transplants of umbilical cord blood or bone marrow from unrelated donors in adult with leukemia
    • V. Rocha, M. Labopin, G. Sanz Transplants of umbilical cord blood or bone marrow from unrelated donors in adult with leukemia N Engl J Med 351 2004 2276 2285
    • (2004) N Engl J Med , vol.351 , pp. 2276-2285
    • Rocha, V.1    Labopin, M.2    Sanz, G.3
  • 9
    • 33947270363 scopus 로고    scopus 로고
    • Expanding the role of umbilical cord blood transplantation
    • C.G. Brunstein, D.C. Setubal, J.E. Wagner Expanding the role of umbilical cord blood transplantation Br J Haematol 137 2007 20 35
    • (2007) Br J Haematol , vol.137 , pp. 20-35
    • Brunstein, C.G.1    Setubal, D.C.2    Wagner, J.E.3
  • 10
    • 72449148316 scopus 로고    scopus 로고
    • Umbilical cord blood transplantation: The first 20 years
    • J.E. Wagner, E. Gluckman Umbilical cord blood transplantation: the first 20 years Semin Hematol 47 2010 3 12
    • (2010) Semin Hematol , vol.47 , pp. 3-12
    • Wagner, J.E.1    Gluckman, E.2
  • 11
    • 0032558759 scopus 로고    scopus 로고
    • Treatment of high risk acute leukemia with T-cell-depleted stem cells from related donors with one fully mismatched HLA haplotype
    • F. Aversa, A. Tabilio, A. Velardi Treatment of high risk acute leukemia with T-cell-depleted stem cells from related donors with one fully mismatched HLA haplotype N Engl J Med 339 1998 1186 1193
    • (1998) N Engl J Med , vol.339 , pp. 1186-1193
    • Aversa, F.1    Tabilio, A.2    Velardi, A.3
  • 13
    • 20644470338 scopus 로고    scopus 로고
    • Full-haplotype mismatched hematopoietic stem cell transplantation: A phase II study in patients with acute leukemia at high risk or relapse
    • F. Aversa, A. Terenzi, A. Tabilio Full-haplotype mismatched hematopoietic stem cell transplantation: a phase II study in patients with acute leukemia at high risk or relapse J Clin Oncol 23 2005 3447 3454
    • (2005) J Clin Oncol , vol.23 , pp. 3447-3454
    • Aversa, F.1    Terenzi, A.2    Tabilio, A.3
  • 14
    • 53149087795 scopus 로고    scopus 로고
    • Hematopoietic SCT from partially HLA-mismatched (HLA-haploidentical) related donors
    • H.J. Symons, E.J. Fuchs Hematopoietic SCT from partially HLA-mismatched (HLA-haploidentical) related donors Bone Marrow Transplant 42 2008 365 377
    • (2008) Bone Marrow Transplant , vol.42 , pp. 365-377
    • Symons, H.J.1    Fuchs, E.J.2
  • 15
    • 82955217779 scopus 로고    scopus 로고
    • Haploidentical hematopoietic transplantation: Current status and future perspectives
    • Y. Reisner, D. Hagin, M.F. Martelli Haploidentical hematopoietic transplantation: current status and future perspectives Blood 118 2011 6006 6017
    • (2011) Blood , vol.118 , pp. 6006-6017
    • Reisner, Y.1    Hagin, D.2    Martelli, M.F.3
  • 16
    • 14944355535 scopus 로고    scopus 로고
    • MHC class i molecules and KIRs in human history, health and survival
    • P. Parham MHC class I molecules and KIRs in human history, health and survival Nat Rev Immunol 5 2005 201 214
    • (2005) Nat Rev Immunol , vol.5 , pp. 201-214
    • Parham, P.1
  • 17
    • 33645070552 scopus 로고    scopus 로고
    • Roles for HLA and KIR polymorphisms in natural killer cell repertoire selection and modulation of effector function
    • M. Yawata, N. Yawata, M. Draghi, A.M. Little, F. Parteniou, P. Parham Roles for HLA and KIR polymorphisms in natural killer cell repertoire selection and modulation of effector function J Exp Med 203 2006 633 645
    • (2006) J Exp Med , vol.203 , pp. 633-645
    • Yawata, M.1    Yawata, N.2    Draghi, M.3    Little, A.M.4    Parteniou, F.5    Parham, P.6
  • 18
    • 0347994940 scopus 로고    scopus 로고
    • Determinants of antileukemia effects of allogeneic NK cells
    • W. Leung, R. Iyengar, V. Turner Determinants of antileukemia effects of allogeneic NK cells J Immunol 172 2004 644 650
    • (2004) J Immunol , vol.172 , pp. 644-650
    • Leung, W.1    Iyengar, R.2    Turner, V.3
  • 19
    • 0037086131 scopus 로고    scopus 로고
    • Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants
    • L. Ruggeri, M. Capanni, E. Urbani Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants Science 295 2002 2097 2100
    • (2002) Science , vol.295 , pp. 2097-2100
    • Ruggeri, L.1    Capanni, M.2    Urbani, E.3
  • 20
    • 0036716947 scopus 로고    scopus 로고
    • NK cells: A lesson from mismatched hematopoietic transplantation
    • A. Velardi, L. Ruggeri, A. Moretta, L. Moretta NK cells: a lesson from mismatched hematopoietic transplantation Trends Immunol 23 2002 438 444
    • (2002) Trends Immunol , vol.23 , pp. 438-444
    • Velardi, A.1    Ruggeri, L.2    Moretta, A.3    Moretta, L.4
  • 21
    • 4444243490 scopus 로고    scopus 로고
    • Killer immunoglobulin-like receptors
    • L. Moretta, A. Moretta Killer immunoglobulin-like receptors Curr Opin Immunol 16 2004 626 633
    • (2004) Curr Opin Immunol , vol.16 , pp. 626-633
    • Moretta, L.1    Moretta, A.2
  • 22
    • 34347396957 scopus 로고    scopus 로고
    • Donor natural killer cell allorecognition of missing self in haploidentical hematopoietic transplantation for acute myeloid leukemia: Challenging its predictive value
    • L. Ruggeri, A. Mancusi, M. Capanni Donor natural killer cell allorecognition of missing self in haploidentical hematopoietic transplantation for acute myeloid leukemia: challenging its predictive value Blood 110 2007 433 440
    • (2007) Blood , vol.110 , pp. 433-440
    • Ruggeri, L.1    Mancusi, A.2    Capanni, M.3
  • 24
    • 0033168770 scopus 로고    scopus 로고
    • Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation
    • L. Ruggeri, M. Capanni, M. Casucci Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation Blood 94 1999 333 339
    • (1999) Blood , vol.94 , pp. 333-339
    • Ruggeri, L.1    Capanni, M.2    Casucci, M.3
  • 25
    • 53249123609 scopus 로고    scopus 로고
    • Survival after T cell-depleted haploidentical stem cell transplantation is improved using the mother as donor
    • M. Stern, L. Ruggeri, A. Mancusi Survival after T cell-depleted haploidentical stem cell transplantation is improved using the mother as donor Blood 112 2008 2990 2995
    • (2008) Blood , vol.112 , pp. 2990-2995
    • Stern, M.1    Ruggeri, L.2    Mancusi, A.3
  • 26
    • 78751689960 scopus 로고    scopus 로고
    • Killer Ig-like receptor-mediated control of natural killer cell alloreactivity in haploidentical hematopoietic stem cell transplantation
    • L. Moretta, F. Locatelli, D. Pende, E. Marcenaro, M.C. Mingari, A. Moretta Killer Ig-like receptor-mediated control of natural killer cell alloreactivity in haploidentical hematopoietic stem cell transplantation Blood 117 2011 764 771
    • (2011) Blood , vol.117 , pp. 764-771
    • Moretta, L.1    Locatelli, F.2    Pende, D.3    Marcenaro, E.4    Mingari, M.C.5    Moretta, A.6
  • 27
    • 77956563350 scopus 로고    scopus 로고
    • Is there an impact of killer cell immunoglobulin-like receptors and KIR-ligand incompatibilities on outcomes after unrelated cord blood stem cell transplantation?
    • Eurocord and of the European Group of Blood and Marrow Transplantation
    • R. Willemze, A. Ruggeri, D. Purtill Eurocord and of the European Group of Blood and Marrow Transplantation Is there an impact of killer cell immunoglobulin-like receptors and KIR-ligand incompatibilities on outcomes after unrelated cord blood stem cell transplantation? Best Pract Res Clin Haematol 23 2010 283 290
    • (2010) Best Pract Res Clin Haematol , vol.23 , pp. 283-290
    • Willemze, R.1    Ruggeri, A.2    Purtill, D.3
  • 28
    • 0025011798 scopus 로고
    • Effect of HLA incompatibility on graft-versus-host disease, relapse, and survival after marrow transplantation for patients with leukemia or lymphoma
    • C. Anasetti, P.G. Beatty, R. Storb Effect of HLA incompatibility on graft-versus-host disease, relapse, and survival after marrow transplantation for patients with leukemia or lymphoma Hum Immunol 29 1990 79 91
    • (1990) Hum Immunol , vol.29 , pp. 79-91
    • Anasetti, C.1    Beatty, P.G.2    Storb, R.3
  • 29
    • 0022521334 scopus 로고
    • Clonable T lymphocytes in T cell-depleted bone marrow transplants correlate with development of graft-v-host disease
    • N.A. Kernan, N.H. Collins, L. Juliano, T. Cartagena, B. Dupont, R.J. O'Reilly Clonable T lymphocytes in T cell-depleted bone marrow transplants correlate with development of graft-v-host disease Blood 68 1986 770 773
    • (1986) Blood , vol.68 , pp. 770-773
    • Kernan, N.A.1    Collins, N.H.2    Juliano, L.3    Cartagena, T.4    Dupont, B.5    O'Reilly, R.J.6
  • 30
    • 2242420757 scopus 로고
    • Demonstration of clonable alloreactive host T cells in a primate model for bone marrow transplantation
    • Y. Reisner, I. Ben-Bassat, D. Douer, A. Kaploon, E. Schwartz, B. Ramot Demonstration of clonable alloreactive host T cells in a primate model for bone marrow transplantation Proc Natl Acad Sci U S A 83 1986 4012 4015
    • (1986) Proc Natl Acad Sci U S A , vol.83 , pp. 4012-4015
    • Reisner, Y.1    Ben-Bassat, I.2    Douer, D.3    Kaploon, A.4    Schwartz, E.5    Ramot, B.6
  • 31
    • 0023189896 scopus 로고
    • Graft rejection in recipients of T cell depleted HLA-nonidentical marrow transplants for leukemia: Identification of host derived anti-donor allocytotoxic T lymphocytes
    • N.A. Kernan, N. Flomemberg, B. Dupont, R.J. O'Reilly Graft rejection in recipients of T cell depleted HLA-nonidentical marrow transplants for leukemia: identification of host derived anti-donor allocytotoxic T lymphocytes Transplantation 43 1987 482 487
    • (1987) Transplantation , vol.43 , pp. 482-487
    • Kernan, N.A.1    Flomemberg, N.2    Dupont, B.3    O'Reilly, R.J.4
  • 32
    • 0030965273 scopus 로고
    • Use of partially mismatched related donors extends access to allogeneic marrow transplant
    • P.J. Henslee-Downey, S.H. Abhyankar, R.S. Parrish Use of partially mismatched related donors extends access to allogeneic marrow transplant Blood 89 1987 3864 3872
    • (1987) Blood , vol.89 , pp. 3864-3872
    • Henslee-Downey, P.J.1    Abhyankar, S.H.2    Parrish, R.S.3
  • 33
    • 0020691120 scopus 로고
    • Transplantation for severe combined immunodeficiency with HLA-A, B, D, DR incompatible parental marrow cells fractionated by soybean agglutinin and sheep red blood cells
    • Y. Reisner, N. Kapoor, D. Kirkpatrick Transplantation for severe combined immunodeficiency with HLA-A, B, D, DR incompatible parental marrow cells fractionated by soybean agglutinin and sheep red blood cells Blood 61 1983 341 348
    • (1983) Blood , vol.61 , pp. 341-348
    • Reisner, Y.1    Kapoor, N.2    Kirkpatrick, D.3
  • 34
    • 0025817169 scopus 로고
    • Bone marrow transplantation from related donors other than HLA-identical siblings: Effect of T cell depletion
    • R.C. Ash, M.M. Horowitz, R.P. Gale Bone marrow transplantation from related donors other than HLA-identical siblings: effect of T cell depletion Bone Marrow Transplant 7 1991 443 452
    • (1991) Bone Marrow Transplant , vol.7 , pp. 443-452
    • Ash, R.C.1    Horowitz, M.M.2    Gale, R.P.3
  • 35
    • 12144286762 scopus 로고    scopus 로고
    • Bone marrow transplantation from partially HLA-mismatched family donors for acute leukemia: Single-center experience of 201 patients
    • J. Mehta, S. Singhal, A.P. Gee Bone marrow transplantation from partially HLA-mismatched family donors for acute leukemia: single-center experience of 201 patients Bone Marrow Transplant 33 2004 389 396
    • (2004) Bone Marrow Transplant , vol.33 , pp. 389-396
    • Mehta, J.1    Singhal, S.2    Gee, A.P.3
  • 36
    • 0025022248 scopus 로고
    • Engraftment of T-cell-depleted bone marrow in murine models for allogeneic bone marrow transplantation
    • Y. Reisner Engraftment of T-cell-depleted bone marrow in murine models for allogeneic bone marrow transplantation Cancer Treat Res 50 1990 9 25
    • (1990) Cancer Treat Res , vol.50 , pp. 9-25
    • Reisner, Y.1
  • 37
    • 0028789191 scopus 로고
    • Megadose of T cell-depleted bone marrow overcomes MHC barriers in sublethally irradiated mice
    • E. Bachar-Lusting, N. Rachamim, H.W. Li, F. Lan, Y. Reisner Megadose of T cell-depleted bone marrow overcomes MHC barriers in sublethally irradiated mice Nat Med 1 1995 1268 1273
    • (1995) Nat Med , vol.1 , pp. 1268-1273
    • Bachar-Lusting, E.1    Rachamim, N.2    Li, H.W.3    Lan, F.4    Reisner, Y.5
  • 38
    • 0032571946 scopus 로고    scopus 로고
    • Tolerance induction by "megadose" hematopoietic transplants: Donor-type human CD34 stem cells induce potent specific reduction of host anti-donor cytotoxic T lymphocyte precursors in mixed lymphocyte culture
    • N. Rachamin, J. Gan, H. Segall Tolerance induction by "megadose" hematopoietic transplants: donor-type human CD34 stem cells induce potent specific reduction of host anti-donor cytotoxic T lymphocyte precursors in mixed lymphocyte culture Transplantation 65 1998 1386 1393
    • (1998) Transplantation , vol.65 , pp. 1386-1393
    • Rachamin, N.1    Gan, J.2    Segall, H.3
  • 39
    • 0036624744 scopus 로고    scopus 로고
    • Tolerance induction by megadose hematopoietic progenitor cells: Expansion of veto cells by short-term culture of purified human CD34(+) cells
    • H. Gur, R. Krauthgamer, A. Berrebi Tolerance induction by megadose hematopoietic progenitor cells: expansion of veto cells by short-term culture of purified human CD34(+) cells Blood 99 2002 4174 4181
    • (2002) Blood , vol.99 , pp. 4174-4181
    • Gur, H.1    Krauthgamer, R.2    Berrebi, A.3
  • 40
    • 20144373526 scopus 로고    scopus 로고
    • Immune regulatory activity of CD34+ progenitor cells: Evidence for a deletion-based mechanism mediated by TNF-alpha
    • H. Gur, R. Krauthgamer, E. Bachar-Lustig Immune regulatory activity of CD34+ progenitor cells: evidence for a deletion-based mechanism mediated by TNF-alpha Blood 105 2005 2585 2593
    • (2005) Blood , vol.105 , pp. 2585-2593
    • Gur, H.1    Krauthgamer, R.2    Bachar-Lustig, E.3
  • 41
    • 0028125191 scopus 로고
    • Successful engraftment of T-cell-depleted haploidentical "three-loci" incompatible transplants in leukemia patients by addition of recombinant human granulocyte colony-stimulating factor-mobilized peripheral blood progenitor cells to bone marrow inoculum
    • F. Aversa, A. Tabilio, A. Terenzi Successful engraftment of T-cell-depleted haploidentical "three-loci" incompatible transplants in leukemia patients by addition of recombinant human granulocyte colony-stimulating factor-mobilized peripheral blood progenitor cells to bone marrow inoculum Blood 84 1994 3948 3955
    • (1994) Blood , vol.84 , pp. 3948-3955
    • Aversa, F.1    Tabilio, A.2    Terenzi, A.3
  • 42
    • 0029830510 scopus 로고    scopus 로고
    • Efficacy of fludarabine as an immunosuppressor for bone marrow transplantation conditioning: Preliminary results
    • A. Terenzi, C. Aristei, F. Aversa Efficacy of fludarabine as an immunosuppressor for bone marrow transplantation conditioning: preliminary results Transplant Proc 28 1996 3101
    • (1996) Transplant Proc , vol.28 , pp. 3101
    • Terenzi, A.1    Aristei, C.2    Aversa, F.3
  • 43
    • 1542577210 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of anti-thymocyte globulin in recipients of partially HLA-matched blood hematopoietic progenitor cell transplantation
    • E.K. Waller, A.A. Langston, S. Lonial Pharmacokinetics and pharmacodynamics of anti-thymocyte globulin in recipients of partially HLA-matched blood hematopoietic progenitor cell transplantation Biol Blood Marrow Transplant 9 2003 460 471
    • (2003) Biol Blood Marrow Transplant , vol.9 , pp. 460-471
    • Waller, E.K.1    Langston, A.A.2    Lonial, S.3
  • 44
    • 0025100777 scopus 로고
    • Graft-versus-leukemia reactions after bone marrow transplantation
    • M.M. Horowitz, R.P. Gale, P.M. Sondel Graft-versus-leukemia reactions after bone marrow transplantation Blood 75 1990 555 562
    • (1990) Blood , vol.75 , pp. 555-562
    • Horowitz, M.M.1    Gale, R.P.2    Sondel, P.M.3
  • 45
    • 0026049124 scopus 로고
    • T-cell depletion of HLA-identical transplants in leukemia
    • A.M. Marmont, M.M. Horowitz, R.P. Gale T-cell depletion of HLA-identical transplants in leukemia Blood 78 1991 2120 2130
    • (1991) Blood , vol.78 , pp. 2120-2130
    • Marmont, A.M.1    Horowitz, M.M.2    Gale, R.P.3
  • 46
    • 77953373822 scopus 로고    scopus 로고
    • Separating graft-versus-leukemia from graft-versus-host disease in allogeneic hematopoietic stem cell transplantation
    • J.M. Li, C.R. Giver, Y. Lu, M.S. Hossain, M. Akhtari, E.K. Waller Separating graft-versus-leukemia from graft-versus-host disease in allogeneic hematopoietic stem cell transplantation Immunotherapy 1 2009 599 621
    • (2009) Immunotherapy , vol.1 , pp. 599-621
    • Li, J.M.1    Giver, C.R.2    Lu, Y.3    Hossain, M.S.4    Akhtari, M.5    Waller, E.K.6
  • 47
    • 36548999731 scopus 로고    scopus 로고
    • The haploidentical option for high-risk haematological malignancies
    • F. Aversa, Y. Reisner, M.F. Martelli The haploidentical option for high-risk haematological malignancies Blood Cells Mol Dis 40 2008 8 12
    • (2008) Blood Cells Mol Dis , vol.40 , pp. 8-12
    • Aversa, F.1    Reisner, Y.2    Martelli, M.F.3
  • 48
    • 55749091291 scopus 로고    scopus 로고
    • A survey of fully haploidentical hematopoietic stem cell transplantation in adults with high-risk acute leukemia: A risk factor analysis of outcomes for patients in remission at transplantation
    • F. Ciceri, M. Labopin, F. Aversa A survey of fully haploidentical hematopoietic stem cell transplantation in adults with high-risk acute leukemia: a risk factor analysis of outcomes for patients in remission at transplantation Blood 112 2008 3574 3581
    • (2008) Blood , vol.112 , pp. 3574-3581
    • Ciceri, F.1    Labopin, M.2    Aversa, F.3
  • 49
    • 17844362968 scopus 로고    scopus 로고
    • Megadose transplantation of purified peripheral blood CD34+ progenitor cells from HLA-mismatched parental donors in children
    • R. Handgretinger, T. Klingebiel, P. Lang Megadose transplantation of purified peripheral blood CD34+ progenitor cells from HLA-mismatched parental donors in children Bone Marrow Transplant 27 2001 777 783
    • (2001) Bone Marrow Transplant , vol.27 , pp. 777-783
    • Handgretinger, R.1    Klingebiel, T.2    Lang, P.3
  • 50
    • 7444249606 scopus 로고    scopus 로고
    • Long-term outcome after haploidentical stem cell transplantation in children
    • P. Lang, J. Greil, P. Bader Long-term outcome after haploidentical stem cell transplantation in children Blood Cells Mol Dis 33 2004 281 287
    • (2004) Blood Cells Mol Dis , vol.33 , pp. 281-287
    • Lang, P.1    Greil, J.2    Bader, P.3
  • 51
    • 70349762668 scopus 로고    scopus 로고
    • Haploidentical hemopoietic stem cell transplantation for the treatment of high-risk leukemias: How NK cells make the difference
    • F. Locatelli, D. Pende, R. Maccario, M.C. Mingari, A. Moretta, L. Moretta Haploidentical hemopoietic stem cell transplantation for the treatment of high-risk leukemias: how NK cells make the difference Clin Immunol 133 2009 171 178
    • (2009) Clin Immunol , vol.133 , pp. 171-178
    • Locatelli, F.1    Pende, D.2    MacCario, R.3    Mingari, M.C.4    Moretta, A.5    Moretta, L.6
  • 52
    • 77951745554 scopus 로고    scopus 로고
    • Results and factors influencing outcome after fully haploidentical hematopoietic stem cell transplantation in children with very high-risk acute lymphoblastic leukemia: Impact of center size. An analysis on behalf of the Acute Leukemia and Pediatric Disease Working Parties of the European Blood and Marrow Transplant Group
    • T. Klingebiel, J. Cornish, M. Labopin Results and factors influencing outcome after fully haploidentical hematopoietic stem cell transplantation in children with very high-risk acute lymphoblastic leukemia: impact of center size. An analysis on behalf of the Acute Leukemia and Pediatric Disease Working Parties of the European Blood and Marrow Transplant Group Blood 115 2010 3437 3446
    • (2010) Blood , vol.115 , pp. 3437-3446
    • Klingebiel, T.1    Cornish, J.2    Labopin, M.3
  • 53
    • 36549083362 scopus 로고    scopus 로고
    • Haploidentical allogeneic hematopoietic cell transplantation in adults using CD3/CD19 depletion and reduced intensity conditioning: An update
    • W.A. Bethge, M. Haegele, C. Faul Haploidentical allogeneic hematopoietic cell transplantation in adults using CD3/CD19 depletion and reduced intensity conditioning: an update Blood Cells Mol Dis 40 2008 13 19
    • (2008) Blood Cells Mol Dis , vol.40 , pp. 13-19
    • Bethge, W.A.1    Haegele, M.2    Faul, C.3
  • 54
    • 80052979902 scopus 로고    scopus 로고
    • Rapid immune recovery and low TRM in haploidentical stem cell transplantation in children and adolescence using CD3/CD19 depleted stem cells
    • P. Bader, J. Soerensen, A. Jarisch Rapid immune recovery and low TRM in haploidentical stem cell transplantation in children and adolescence using CD3/CD19 depleted stem cells Best Pract Res Clin Haematol 24 2011 331 337
    • (2011) Best Pract Res Clin Haematol , vol.24 , pp. 331-337
    • Bader, P.1    Soerensen, J.2    Jarisch, A.3
  • 55
    • 36849036501 scopus 로고    scopus 로고
    • A large-scale method for the selective depletion of alphabeta T lymphocytes from PBSC for allogeneic transplantation
    • S. Chaleff, M. Otto, R.C. Barfield A large-scale method for the selective depletion of alphabeta T lymphocytes from PBSC for allogeneic transplantation Cytotherapy 9 2007 746 754
    • (2007) Cytotherapy , vol.9 , pp. 746-754
    • Chaleff, S.1    Otto, M.2    Barfield, R.C.3
  • 56
    • 28844459420 scopus 로고    scopus 로고
    • Transferring functional immune responses to pathogens after haploidentical hematopoietic transplantation
    • K. Perruccio, A. Tosti, E. Burchielli Transferring functional immune responses to pathogens after haploidentical hematopoietic transplantation Blood 106 2005 4397 4406
    • (2005) Blood , vol.106 , pp. 4397-4406
    • Perruccio, K.1    Tosti, A.2    Burchielli, E.3
  • 57
    • 78549241330 scopus 로고    scopus 로고
    • Adoptive transfer of pp65-specific T cells for the treatment of chemorefractory cytomegalovirus disease or reactivation after haploidentical and matched unrelated stem cell transplantation
    • T. Feuchtinger, K. Opherk, W.A. Bethge Adoptive transfer of pp65-specific T cells for the treatment of chemorefractory cytomegalovirus disease or reactivation after haploidentical and matched unrelated stem cell transplantation Blood 116 2010 4360 4367
    • (2010) Blood , vol.116 , pp. 4360-4367
    • Feuchtinger, T.1    Opherk, K.2    Bethge, W.A.3
  • 58
    • 74949113395 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantation
    • A.M. Leen, A. Christin, G.D. Myers Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantation Blood 114 2009 4283 4292
    • (2009) Blood , vol.114 , pp. 4283-4292
    • Leen, A.M.1    Christin, A.2    Myers, G.D.3
  • 59
    • 48549101673 scopus 로고    scopus 로고
    • T-cell lines specific for peptides of adenovirus hexon protein and devoid of alloreactivity against recipient cells can be obtained from HLA-haploidentical donors
    • P. Comoli, M.W. Schilham, S. Basso T-cell lines specific for peptides of adenovirus hexon protein and devoid of alloreactivity against recipient cells can be obtained from HLA-haploidentical donors J Immunother 31 2008 529 536
    • (2008) J Immunother , vol.31 , pp. 529-536
    • Comoli, P.1    Schilham, M.W.2    Basso, S.3
  • 60
    • 34248659404 scopus 로고    scopus 로고
    • Preemptive therapy of EBV-related lymphoproliferative disease after pediatric haploidentical stem cell transplantation
    • P. Comoli, S. Basso, M. Zecca Preemptive therapy of EBV-related lymphoproliferative disease after pediatric haploidentical stem cell transplantation Am J Transplant 7 2007 1648 1655
    • (2007) Am J Transplant , vol.7 , pp. 1648-1655
    • Comoli, P.1    Basso, S.2    Zecca, M.3
  • 61
    • 0037441766 scopus 로고    scopus 로고
    • Immunologic potential of donor lymphocytes expressing a suicide gene for early immune reconstitution after hematopoietic T-cell-depleted stem cell transplantation
    • S. Marktel, Z. Magnani, F. Ciceri Immunologic potential of donor lymphocytes expressing a suicide gene for early immune reconstitution after hematopoietic T-cell-depleted stem cell transplantation Blood 101 2003 1290 1298
    • (2003) Blood , vol.101 , pp. 1290-1298
    • Marktel, S.1    Magnani, Z.2    Ciceri, F.3
  • 62
    • 21044453633 scopus 로고    scopus 로고
    • Modulation of GvHD by suicide-gene transduced donor T lymphocytes: Clinical applications in mismatched transplantation
    • F. Ciceri, C. Bonini, C. Gallo-Stampino, C. Bordignon Modulation of GvHD by suicide-gene transduced donor T lymphocytes: clinical applications in mismatched transplantation Cytotherapy 7 2005 144 149
    • (2005) Cytotherapy , vol.7 , pp. 144-149
    • Ciceri, F.1    Bonini, C.2    Gallo-Stampino, C.3    Bordignon, C.4
  • 63
    • 80455162464 scopus 로고    scopus 로고
    • Inducible apoptosis as a safety switch for adoptive cell therapy
    • A. Di Stasi, S.K. Tey, G. Dotti Inducible apoptosis as a safety switch for adoptive cell therapy N Engl J Med 365 2011 1673 1683
    • (2011) N Engl J Med , vol.365 , pp. 1673-1683
    • Di Stasi, A.1    Tey, S.K.2    Dotti, G.3
  • 64
    • 36549052124 scopus 로고    scopus 로고
    • Photodynamic purging of alloreactive T cells for adoptive immunotherapy after haploidentical stem cell transplantation
    • K. Perruccio, F. Topini, A. Tosti Photodynamic purging of alloreactive T cells for adoptive immunotherapy after haploidentical stem cell transplantation Blood Cells Mol Dis 40 2008 76 83
    • (2008) Blood Cells Mol Dis , vol.40 , pp. 76-83
    • Perruccio, K.1    Topini, F.2    Tosti, A.3
  • 65
    • 43249122409 scopus 로고    scopus 로고
    • A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique
    • S. Mielke, R. Nunes, K. Rezvani A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique Blood 111 2008 4392 4402
    • (2008) Blood , vol.111 , pp. 4392-4402
    • Mielke, S.1    Nunes, R.2    Rezvani, K.3
  • 66
    • 78649710409 scopus 로고    scopus 로고
    • Photodepletion differentially affects CD4+ Tregs versus CD4+ effector T cells from patients with chronic graft-versus-host disease
    • J.P. Bastien, G. Krosl, C. Therien Photodepletion differentially affects CD4+ Tregs versus CD4+ effector T cells from patients with chronic graft-versus-host disease Blood 116 2010 4859 4869
    • (2010) Blood , vol.116 , pp. 4859-4869
    • Bastien, J.P.1    Krosl, G.2    Therien, C.3
  • 67
    • 84870682790 scopus 로고    scopus 로고
    • Reduction in incidence of severe infections by transplantation of high doses of haploidentical T cells selectively depleted of alloreactive units
    • [abstract]
    • D.C. Roy, M. Guerin, R.S. Boumedine Reduction in incidence of severe infections by transplantation of high doses of haploidentical T cells selectively depleted of alloreactive units ASH Annual Meeting 118 2011 3020 [abstract]
    • (2011) ASH Annual Meeting , vol.118 , pp. 3020
    • Roy, D.C.1    Guerin, M.2    Boumedine, R.S.3
  • 68
    • 0037025943 scopus 로고    scopus 로고
    • Donor-type CD4+CD25+ regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation
    • P. Hoffmann, J. Ermann, M. Edinger, C.G. Fathman, S. Strober Donor-type CD4+CD25+ regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation J Exp Med 196 2002 389 399
    • (2002) J Exp Med , vol.196 , pp. 389-399
    • Hoffmann, P.1    Ermann, J.2    Edinger, M.3    Fathman, C.G.4    Strober, S.5
  • 69
    • 0141461418 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation
    • M. Edinger, P. Hoffmann, J. Ermann CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation Nat Med 9 2003 1144 1150
    • (2003) Nat Med , vol.9 , pp. 1144-1150
    • Edinger, M.1    Hoffmann, P.2    Ermann, J.3
  • 70
    • 64649098714 scopus 로고    scopus 로고
    • Immunomagnetic isolation of CD4+CD25+FoxP3+ natural T regulatory lymphocytes for clinical applications
    • M. Di Ianni, B. Del Papa, D. Cecchini Immunomagnetic isolation of CD4+CD25+FoxP3+ natural T regulatory lymphocytes for clinical applications Clin Exp Immunol 156 2009 246 253
    • (2009) Clin Exp Immunol , vol.156 , pp. 246-253
    • Di Ianni, M.1    Del Papa, B.2    Cecchini, D.3
  • 71
    • 38349146500 scopus 로고    scopus 로고
    • The impact of regulatory T cells on T-cell immunity following hematopoietic cell transplantation
    • V.H. Nguyen, S. Shashidhar, D.S. Chang The impact of regulatory T cells on T-cell immunity following hematopoietic cell transplantation Blood 111 2008 945 953
    • (2008) Blood , vol.111 , pp. 945-953
    • Nguyen, V.H.1    Shashidhar, S.2    Chang, D.S.3
  • 72
    • 79953809817 scopus 로고    scopus 로고
    • Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation
    • M. Di Ianni, F. Falzetti, A. Carotti Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation Blood 117 2011 3921 3928
    • (2011) Blood , vol.117 , pp. 3921-3928
    • Di Ianni, M.1    Falzetti, F.2    Carotti, A.3
  • 73
    • 78751696183 scopus 로고    scopus 로고
    • Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: Safety profile and detection kinetics
    • C.G. Brunstein, J.S. Miller, Q. Cao Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics Blood 117 2011 1061 1070
    • (2011) Blood , vol.117 , pp. 1061-1070
    • Brunstein, C.G.1    Miller, J.S.2    Cao, Q.3
  • 74
    • 0346690399 scopus 로고    scopus 로고
    • Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia
    • A. Trenado, F. Charlotte, S. Fisson Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia J Clin Invest 112 2003 1688 1696
    • (2003) J Clin Invest , vol.112 , pp. 1688-1696
    • Trenado, A.1    Charlotte, F.2    Fisson, S.3
  • 75
    • 84864144424 scopus 로고    scopus 로고
    • A perspective on the selection of unrelated donors and cord blood units for transplantation
    • S.R. Spellman, M. Eapen, B.R. Logan A perspective on the selection of unrelated donors and cord blood units for transplantation Blood 120 2012 259 265
    • (2012) Blood , vol.120 , pp. 259-265
    • Spellman, S.R.1    Eapen, M.2    Logan, B.R.3
  • 76
    • 0037086191 scopus 로고    scopus 로고
    • A perfect mismatch
    • K. Kärre A perfect mismatch Science 295 2002 2029 2031
    • (2002) Science , vol.295 , pp. 2029-2031
    • Kärre, K.1
  • 77
    • 33750726384 scopus 로고    scopus 로고
    • Allogeneic hematopoietic transplantation and natural killer cell recognition of missing self
    • L. Ruggeri, F. Aversa, M.F. Martelli, A. Velardi Allogeneic hematopoietic transplantation and natural killer cell recognition of missing self Immunol Rev 214 2006 202 218
    • (2006) Immunol Rev , vol.214 , pp. 202-218
    • Ruggeri, L.1    Aversa, F.2    Martelli, M.F.3    Velardi, A.4
  • 78
    • 70349817631 scopus 로고    scopus 로고
    • Natural killer cell allorecognition of missing self in allogeneic hematopoietic transplantation: A tool for immunotherapy of leukemia
    • A. Velardi, L. Ruggeri, A. Mancusi, F. Aversa, F.T. Christiansen Natural killer cell allorecognition of missing self in allogeneic hematopoietic transplantation: a tool for immunotherapy of leukemia Curr Opin Immunol 21 2009 525 530
    • (2009) Curr Opin Immunol , vol.21 , pp. 525-530
    • Velardi, A.1    Ruggeri, L.2    Mancusi, A.3    Aversa, F.4    Christiansen, F.T.5
  • 79
    • 78751693614 scopus 로고    scopus 로고
    • NK-cell education is shaped by donor HLA genotype after unrelated allogeneic hematopoietic stem cell transplantation
    • P. Haas, P. Loiseau, R. Tamouza NK-cell education is shaped by donor HLA genotype after unrelated allogeneic hematopoietic stem cell transplantation Blood 117 2011 1021 1029
    • (2011) Blood , vol.117 , pp. 1021-1029
    • Haas, P.1    Loiseau, P.2    Tamouza, R.3
  • 80
    • 80052649999 scopus 로고    scopus 로고
    • NK cell education after allogeneic transplantation: Dissociation between recovery of cytokine-producing and cytotoxic functions
    • B. Foley, S. Cooley, M.R. Verneris NK cell education after allogeneic transplantation: dissociation between recovery of cytokine-producing and cytotoxic functions Blood 118 2011 2784 2792
    • (2011) Blood , vol.118 , pp. 2784-2792
    • Foley, B.1    Cooley, S.2    Verneris, M.R.3
  • 81
    • 20444394742 scopus 로고    scopus 로고
    • Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia predicted by KIR and HLA genotypes
    • K.C. Hsu, C.A. Keever-Taylor, A. Wilton Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia predicted by KIR and HLA genotypes Blood 105 2005 4878 4884
    • (2005) Blood , vol.105 , pp. 4878-4884
    • Hsu, K.C.1    Keever-Taylor, C.A.2    Wilton, A.3
  • 82
    • 17444428649 scopus 로고    scopus 로고
    • Natural killer cell receptors: Regulating innate immune responses to hematologic malignancies
    • K.C. Hsu, B. Dupont Natural killer cell receptors: regulating innate immune responses to hematologic malignancies Semin Hematol 42 2005 91 103
    • (2005) Semin Hematol , vol.42 , pp. 91-103
    • Hsu, K.C.1    Dupont, B.2
  • 83
    • 77950967504 scopus 로고    scopus 로고
    • NK cells expressing inhibitory KIR for non-self-ligands remain tolerant in HLA-matched sibling stem cell transplantation
    • A.T. Björklund, M. Schaffer, C. Fauriat NK cells expressing inhibitory KIR for non-self-ligands remain tolerant in HLA-matched sibling stem cell transplantation Blood 115 2010 2686 2694
    • (2010) Blood , vol.115 , pp. 2686-2694
    • Björklund, A.T.1    Schaffer, M.2    Fauriat, C.3
  • 84
    • 0037111776 scopus 로고    scopus 로고
    • Evaluation of KIR ligand incompatibility in mismatched unrelated donor hematopoietic transplants Killer immunoglobulin-like receptor
    • S.M. Davies, L. Ruggieri, T. DeFor Evaluation of KIR ligand incompatibility in mismatched unrelated donor hematopoietic transplants Killer immunoglobulin-like receptor Blood 100 2002 3825 3827
    • (2002) Blood , vol.100 , pp. 3825-3827
    • Davies, S.M.1    Ruggieri, L.2    Defor, T.3
  • 85
    • 0142215546 scopus 로고    scopus 로고
    • T-cell alloreactivity dominates natural killer cell alloreactivity in minimally T-cell-depleted HLA-non-identical paediatric bone marrow transplantation
    • E.J. Lowe, V. Turner, R. Handgretinger T-cell alloreactivity dominates natural killer cell alloreactivity in minimally T-cell-depleted HLA-non-identical paediatric bone marrow transplantation Br J Haematol 123 2003 323 326
    • (2003) Br J Haematol , vol.123 , pp. 323-326
    • Lowe, E.J.1    Turner, V.2    Handgretinger, R.3
  • 86
    • 1642377663 scopus 로고    scopus 로고
    • Role of KIR ligand incompatibility in hematopoietic stem cell transplantation using unrelated donors
    • M. Bornhauser, R. Schwerdtfeger, H. Martin, K.H. Frank, C. Theuser, G. Ehninger Role of KIR ligand incompatibility in hematopoietic stem cell transplantation using unrelated donors Blood 103 2004 2860 2861
    • (2004) Blood , vol.103 , pp. 2860-2861
    • Bornhauser, M.1    Schwerdtfeger, R.2    Martin, H.3    Frank, K.H.4    Theuser, C.5    Ehninger, G.6
  • 87
    • 33746096999 scopus 로고    scopus 로고
    • The effect of KIR ligand incompatibility on the outcome of unrelated donor transplantation: A report from the center for International Blood and Marrow Transplant Research, the European Blood and Marrow Transplant Registry, and the Dutch Registry
    • S.S. Farag, A. Bacigalupo, M. Eapen The effect of KIR ligand incompatibility on the outcome of unrelated donor transplantation: a report from the center for International Blood and Marrow Transplant Research, the European Blood and Marrow Transplant Registry, and the Dutch Registry Biol Blood Marrow Transplant 12 2006 876 884
    • (2006) Biol Blood Marrow Transplant , vol.12 , pp. 876-884
    • Farag, S.S.1    Bacigalupo, A.2    Eapen, M.3
  • 88
    • 33750312938 scopus 로고    scopus 로고
    • Low number of donor activating killer immunoglobulin-like receptors (KIR) genes but not KIR-ligand mismatch prevents relapse and improves disease-free survival in leukemia patients after in vivo T-cell depleted unrelated stem cell transplantation
    • N. Kröger, T. Binder, T. Zabelina Low number of donor activating killer immunoglobulin-like receptors (KIR) genes but not KIR-ligand mismatch prevents relapse and improves disease-free survival in leukemia patients after in vivo T-cell depleted unrelated stem cell transplantation Transplantation 82 2006 1024 1030
    • (2006) Transplantation , vol.82 , pp. 1024-1030
    • Kröger, N.1    Binder, T.2    Zabelina, T.3
  • 89
    • 37349058596 scopus 로고    scopus 로고
    • Donor killer immunoglobulin-like receptor (KIR) genotype-patient cognate KIR ligand combination and antithymocyte globulin preadministration are critical factors in outcome of HLA-C-KIR ligand-mismatched T cell-replete unrelated bone marrow transplantation
    • T. Yabe, K. Matsuo, K. Hirayasu Donor killer immunoglobulin-like receptor (KIR) genotype-patient cognate KIR ligand combination and antithymocyte globulin preadministration are critical factors in outcome of HLA-C-KIR ligand-mismatched T cell-replete unrelated bone marrow transplantation Biol Blood Marrow Transplant 14 2008 75 87
    • (2008) Biol Blood Marrow Transplant , vol.14 , pp. 75-87
    • Yabe, T.1    Matsuo, K.2    Hirayasu, K.3
  • 90
    • 10744230735 scopus 로고    scopus 로고
    • Survival advantage with KIR ligand incompatibility in hematopoietic stem cell transplantation from unrelated donors
    • S. Giebel, F. Locatelli, T. Lamparelli Survival advantage with KIR ligand incompatibility in hematopoietic stem cell transplantation from unrelated donors Blood 102 2003 814 819
    • (2003) Blood , vol.102 , pp. 814-819
    • Giebel, S.1    Locatelli, F.2    Lamparelli, T.3
  • 91
    • 15244346488 scopus 로고    scopus 로고
    • Genotypic inhibitory killer immunoglobulin-like receptor ligand incompatibility enhances the long-term antileukemic effect of unmodified allogeneic hematopoietic stem cell transplantation in patients with myeloid leukemias
    • D.W. Beelen, H.D. Ottinger, S. Ferencik Genotypic inhibitory killer immunoglobulin-like receptor ligand incompatibility enhances the long-term antileukemic effect of unmodified allogeneic hematopoietic stem cell transplantation in patients with myeloid leukemias Blood 105 2005 2594 2600
    • (2005) Blood , vol.105 , pp. 2594-2600
    • Beelen, D.W.1    Ottinger, H.D.2    Ferencik, S.3
  • 92
    • 21244462753 scopus 로고    scopus 로고
    • Reduced risk for molecular disease in patients with chronic myeloid leukemia after transplantation from a KIR-mismatched donor
    • A.H. Elmaagacli, H. Ottinger, M. Koldehoff Reduced risk for molecular disease in patients with chronic myeloid leukemia after transplantation from a KIR-mismatched donor Transplantation 79 2005 1741 1747
    • (2005) Transplantation , vol.79 , pp. 1741-1747
    • Elmaagacli, A.H.1    Ottinger, H.2    Koldehoff, M.3
  • 93
    • 20444463165 scopus 로고    scopus 로고
    • Comparison between antithymocyte globulin and alemtuzumab and the possible impact of KIR-ligand mismatch after dose-reduced conditioning and unrelated stem cell transplantation in patients with multiple myeloma
    • N. Kröger, B. Shaw, S. Iacobelli Comparison between antithymocyte globulin and alemtuzumab and the possible impact of KIR-ligand mismatch after dose-reduced conditioning and unrelated stem cell transplantation in patients with multiple myeloma Br J Haematol 129 2005 631 643
    • (2005) Br J Haematol , vol.129 , pp. 631-643
    • Kröger, N.1    Shaw, B.2    Iacobelli, S.3
  • 94
    • 22344450421 scopus 로고    scopus 로고
    • Successful use of haploidentical stem-cell transplantation with KIR mismatch as initial therapy for poor-risk myelodysplastic syndrome
    • M.A. Dawson, A. Spencer Successful use of haploidentical stem-cell transplantation with KIR mismatch as initial therapy for poor-risk myelodysplastic syndrome J Clin Oncol 23 2005 4473 4474
    • (2005) J Clin Oncol , vol.23 , pp. 4473-4474
    • Dawson, M.A.1    Spencer, A.2
  • 95
    • 62549084678 scopus 로고    scopus 로고
    • KIR-ligand incompatibility in the graft-versus-host direction improves outcomes after umbilical cord blood transplantation for acute leukemia
    • R. Willemze, C.A. Rodrigues, M. Labopin KIR-ligand incompatibility in the graft-versus-host direction improves outcomes after umbilical cord blood transplantation for acute leukemia Leukemia 23 2009 492 500
    • (2009) Leukemia , vol.23 , pp. 492-500
    • Willemze, R.1    Rodrigues, C.A.2    Labopin, M.3
  • 96
    • 67049088404 scopus 로고    scopus 로고
    • Negative effect of KIR alloreactivity in recipients of umbilical cord blood transplant depends on transplantation conditioning intensity
    • C.G. Brunstein, J.E. Wagner, D.J. Weisdorf Negative effect of KIR alloreactivity in recipients of umbilical cord blood transplant depends on transplantation conditioning intensity Blood 113 2009 5628 5634
    • (2009) Blood , vol.113 , pp. 5628-5634
    • Brunstein, C.G.1    Wagner, J.E.2    Weisdorf, D.J.3
  • 97
    • 65349157330 scopus 로고    scopus 로고
    • Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): A non-randomised phase I-II study
    • F. Ciceri, C. Bonini, M.T.L. Stanghellini Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study Lancet Oncol 10 2009 489 500
    • (2009) Lancet Oncol , vol.10 , pp. 489-500
    • Ciceri, F.1    Bonini, C.2    Stanghellini, M.T.L.3
  • 98
    • 54049142121 scopus 로고    scopus 로고
    • Temporal, quantitative, and functional characteristics of single-KIR-positive alloreactive natural killer cell recovery account for impaired graft-versus-leukemia activity after haploidentical hematopoietic stem cell transplantation
    • L. Vago, B. Forno, M.P. Sormani Temporal, quantitative, and functional characteristics of single-KIR-positive alloreactive natural killer cell recovery account for impaired graft-versus-leukemia activity after haploidentical hematopoietic stem cell transplantation Blood 112 2008 3488 3499
    • (2008) Blood , vol.112 , pp. 3488-3499
    • Vago, L.1    Forno, B.2    Sormani, M.P.3
  • 99
    • 20144388509 scopus 로고    scopus 로고
    • Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer
    • J.S. Miller, Y. Soignier, A. Panoskaltsis-Mortari Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer Blood 105 2005 3051 3057
    • (2005) Blood , vol.105 , pp. 3051-3057
    • Miller, J.S.1    Soignier, Y.2    Panoskaltsis-Mortari, A.3
  • 100
    • 77949898005 scopus 로고    scopus 로고
    • NKAML: A pilot study to determine the safety and feasibility of haploidentical natural killer cell transplantation in childhood acute myeloid leukemia
    • J.E. Rubnitz, H. Inaba, R.C. Ribeiro NKAML: a pilot study to determine the safety and feasibility of haploidentical natural killer cell transplantation in childhood acute myeloid leukemia J Clin Oncol 28 2010 955 959
    • (2010) J Clin Oncol , vol.28 , pp. 955-959
    • Rubnitz, J.E.1    Inaba, H.2    Ribeiro, R.C.3
  • 101
    • 80053208226 scopus 로고    scopus 로고
    • Successful transfer of alloreactive haploidentical KIR ligand-mismatched natural killer cells after infusion in elderly high risk acute myeloid leukemia patients
    • A. Curti, L. Ruggeri, A. D'Addio Successful transfer of alloreactive haploidentical KIR ligand-mismatched natural killer cells after infusion in elderly high risk acute myeloid leukemia patients Blood 118 2011 3273 3279
    • (2011) Blood , vol.118 , pp. 3273-3279
    • Curti, A.1    Ruggeri, L.2    D'Addio, A.3
  • 102
    • 69249108787 scopus 로고    scopus 로고
    • Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells
    • F. Romagné, P. André, P. Spee Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells Blood 114 2009 2667 2677
    • (2009) Blood , vol.114 , pp. 2667-2677
    • Romagné, F.1    André, P.2    Spee, P.3
  • 103
    • 84858650013 scopus 로고    scopus 로고
    • Natural revenge over cytomegalovirus
    • A. Velardi Natural revenge over cytomegalovirus Blood 119 2012 2438 2439
    • (2012) Blood , vol.119 , pp. 2438-2439
    • Velardi, A.1
  • 104
    • 84863338121 scopus 로고    scopus 로고
    • Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function
    • B. Foley, S. Cooley, M.R. Verneris Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function Blood 119 2012 2665 2674
    • (2012) Blood , vol.119 , pp. 2665-2674
    • Foley, B.1    Cooley, S.2    Verneris, M.R.3
  • 105
    • 80053133221 scopus 로고    scopus 로고
    • NK cell development, homeostasis and function: Parallels with CD8+ T cells
    • J.C. Sun, L.L. Lanier NK cell development, homeostasis and function: parallels with CD8+ T cells Nat Rev Immunol 11 2011 645 657
    • (2011) Nat Rev Immunol , vol.11 , pp. 645-657
    • Sun, J.C.1    Lanier, L.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.