Transcriptome correlation analysis identifies two unique craniosynostosis subtypes associated with IRS1 activation

Physiological Genomics

Volumn 44, Issue 23, 2012, Pages 1154-1163

  Stamper, B D ^a   Mecham, B ^b   Park, S S ^a   Wilkerson, H ^c   Farin, F M ^c   Beyer, R P ^c   Bammler, T K ^c   Mangravite, L M ^b   Cunningham, M L ^a,d  

^a SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

^b SAGE BIONETWORKS   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Craniosynostosis; IGF1; IRS1; Metagenomics; Subtyping

Indexed keywords

ALPHA5 INTEGRIN; BETA1 INTEGRIN; BETA3 INTEGRIN; FIBROBLAST GROWTH FACTOR 9; GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN RECEPTOR SUBSTRATE 1; INTEGRIN; KERATINOCYTE GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PROTEIN KINASE B; SOMATOMEDIN; SOMATOMEDIN C RECEPTOR; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTOME;

ARTICLE; CONTROLLED STUDY; CRANIOFACIAL SYNOSTOSIS; ENZYME ACTIVATION; GENE EXPRESSION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

CELL LINE; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; CLUSTER ANALYSIS; CRANIOSYNOSTOSES; GLYCOGEN SYNTHASE KINASE 3; HUMANS; INFANT; INSULIN RECEPTOR SUBSTRATE PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSTEOBLASTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, IGF TYPE 1; RIBOSOMAL PROTEIN S6; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION; TRANSCRIPTOME;

EID: 84870707631     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00085.2012     Document Type: Article

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